JP2010514751A - オレキシン受容体拮抗薬としての２−アザ−ビシクロ［３．１．０］ヘキサン誘導体 - Google Patents

オレキシン受容体拮抗薬としての２−アザ−ビシクロ［３．１．０］ヘキサン誘導体 Download PDF

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Publication number
JP2010514751A
JP2010514751A JP2009543566A JP2009543566A JP2010514751A JP 2010514751 A JP2010514751 A JP 2010514751A JP 2009543566 A JP2009543566 A JP 2009543566A JP 2009543566 A JP2009543566 A JP 2009543566A JP 2010514751 A JP2010514751 A JP 2010514751A
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thiazole
aza
bicyclo
methyl
carboxylic acid
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JP2009543566A
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Japanese (ja)
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JP2010514751A5 (cg-RX-API-DMAC7.html
Inventor
アイサオウイ ハメッド
ボス クリストフ
グード マーカス
コバースタイン ラルフ
セィファーレン ティエリー
トラッシェル ダニエル
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Actelion Pharmaceuticals Ltd
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Actelion Pharmaceuticals Ltd
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Publication of JP2010514751A publication Critical patent/JP2010514751A/ja
Publication of JP2010514751A5 publication Critical patent/JP2010514751A5/ja
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    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Emergency Medicine (AREA)
  • Reproductive Health (AREA)
  • Immunology (AREA)
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  • Dermatology (AREA)
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JP2009543566A 2006-12-28 2007-12-28 オレキシン受容体拮抗薬としての２−アザ−ビシクロ［３．１．０］ヘキサン誘導体 Pending JP2010514751A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2006055042 2006-12-28
PCT/IB2007/055326 WO2008081399A2 (en) 2006-12-28 2007-12-28 2-aza-bicyclo[3.1.0]hexane derivatives as orexin receptor antagonists

Publications (2)

Publication Number Publication Date
JP2010514751A true JP2010514751A (ja) 2010-05-06
JP2010514751A5 JP2010514751A5 (cg-RX-API-DMAC7.html) 2011-02-17

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JP2009543566A Pending JP2010514751A (ja) 2006-12-28 2007-12-28 オレキシン受容体拮抗薬としての２−アザ−ビシクロ［３．１．０］ヘキサン誘導体

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US (1) US8288435B2 (cg-RX-API-DMAC7.html)
EP (1) EP2094690B1 (cg-RX-API-DMAC7.html)
JP (1) JP2010514751A (cg-RX-API-DMAC7.html)
KR (1) KR20090094168A (cg-RX-API-DMAC7.html)
CN (1) CN101568536B (cg-RX-API-DMAC7.html)
AR (1) AR064561A1 (cg-RX-API-DMAC7.html)
AT (1) ATE505467T1 (cg-RX-API-DMAC7.html)
AU (1) AU2007340944B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0720876A2 (cg-RX-API-DMAC7.html)
CA (1) CA2669821A1 (cg-RX-API-DMAC7.html)
CL (1) CL2007003827A1 (cg-RX-API-DMAC7.html)
CY (1) CY1111705T1 (cg-RX-API-DMAC7.html)
DE (1) DE602007013937D1 (cg-RX-API-DMAC7.html)
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ES (1) ES2364297T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20110509T1 (cg-RX-API-DMAC7.html)
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MY (1) MY157344A (cg-RX-API-DMAC7.html)
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PT (1) PT2094690E (cg-RX-API-DMAC7.html)
RU (1) RU2460732C2 (cg-RX-API-DMAC7.html)
SI (1) SI2094690T1 (cg-RX-API-DMAC7.html)
TW (1) TW200833328A (cg-RX-API-DMAC7.html)
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010504957A (ja) * 2006-09-29 2010-02-18 アクテリオン ファーマシューティカルズ リミテッド ３−アザ−ビシクロ［３．１．０］ヘキサン誘導体
JP2015502385A (ja) * 2011-12-21 2015-01-22 ロッタファーム・バイオテック・ソチエタ・ア・レスポンサビリタ・リミタータＲＯＴＴＡＰＨＡＲＭ ＢＩＯＴＥＣＨ Ｓ．ｒ．ｌ． 化学化合物
JP2015510909A (ja) * 2012-03-19 2015-04-13 ロッタファーム・バイオテック・ソチエタ・ア・レスポンサビリタ・リミタータＲＯＴＴＡＰＨＡＲＭ ＢＩＯＴＥＣＨ Ｓ．ｒ．ｌ． 化合物
JP2015522622A (ja) * 2012-07-18 2015-08-06 モラスキ，ギャレット ５，５−ヘテロ芳香族抗感染症化合物
JP2024504854A (ja) * 2021-02-02 2024-02-01 メッドシャイン ディスカバリー インコーポレイテッド テトラヒドロピロロ環化合物及びその使用

Families Citing this family (40)

* Cited by examiner, † Cited by third party
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