MX2009009690A - Derivados de tiazolidina como antagonistas del receptor de orexina. - Google Patents

Derivados de tiazolidina como antagonistas del receptor de orexina.

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Publication number
MX2009009690A
MX2009009690A MX2009009690A MX2009009690A MX2009009690A MX 2009009690 A MX2009009690 A MX 2009009690A MX 2009009690 A MX2009009690 A MX 2009009690A MX 2009009690 A MX2009009690 A MX 2009009690A MX 2009009690 A MX2009009690 A MX 2009009690A
Authority
MX
Mexico
Prior art keywords
receptor antagonists
orexin receptor
thiazolidine derivatives
derivatives
thiazolidine
Prior art date
Application number
MX2009009690A
Other languages
English (en)
Inventor
Ralf Koberstein
Thierry Sifferlen
Hamed Aissaoui
Christoph Boss
Markus Gude
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of MX2009009690A publication Critical patent/MX2009009690A/es

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    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Abstract

La invención se relaciona con derivados tiazolidina de fórmula (I) (ver fórmula I) en donde A y R1 son tal como se describe en la descripción y su uso como medicamentos, en especial como antagonistas del receptor de orexina.
MX2009009690A 2007-03-26 2008-03-25 Derivados de tiazolidina como antagonistas del receptor de orexina. MX2009009690A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IB2007051048 2007-03-26
IB2008050620 2008-02-21
PCT/IB2008/051110 WO2008117241A2 (en) 2007-03-26 2008-03-25 Thiazolidine derivatives as orexin receptor antagonists

Publications (1)

Publication Number Publication Date
MX2009009690A true MX2009009690A (es) 2009-12-14

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Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009009690A MX2009009690A (es) 2007-03-26 2008-03-25 Derivados de tiazolidina como antagonistas del receptor de orexina.

Country Status (17)

Country Link
US (1) US8236964B2 (es)
EP (1) EP2125760A2 (es)
JP (1) JP2010522737A (es)
KR (1) KR20090125195A (es)
CN (1) CN101641342B (es)
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AU2008231441A1 (en) 2008-10-02
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CN101641342A (zh) 2010-02-03
IL201112A0 (en) 2010-05-17
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TW200901988A (en) 2009-01-16
KR20090125195A (ko) 2009-12-03
CL2008000836A1 (es) 2008-11-07
EP2125760A2 (en) 2009-12-02
MA31289B1 (fr) 2010-04-01
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