PL2069332T3 - Związki azetydynowe jako antagoniści receptorów oreksynowych - Google Patents

Związki azetydynowe jako antagoniści receptorów oreksynowych

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Publication number
PL2069332T3
PL2069332T3 PL07826034T PL07826034T PL2069332T3 PL 2069332 T3 PL2069332 T3 PL 2069332T3 PL 07826034 T PL07826034 T PL 07826034T PL 07826034 T PL07826034 T PL 07826034T PL 2069332 T3 PL2069332 T3 PL 2069332T3
Authority
PL
Poland
Prior art keywords
receptor antagonists
orexin receptor
azetidine compounds
compounds
azetidine
Prior art date
Application number
PL07826034T
Other languages
English (en)
Inventor
Hamed Aissaoui
Christoph Boss
Markus Gude
Ralf Koberstein
Thierry Sifferlen
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of PL2069332T3 publication Critical patent/PL2069332T3/pl

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    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
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PL07826034T 2006-08-15 2007-08-15 Związki azetydynowe jako antagoniści receptorów oreksynowych PL2069332T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IB2006052814 2006-08-15
EP07826034A EP2069332B1 (en) 2006-08-15 2007-08-15 Azetidine compounds as orexin receptor antagonists
PCT/IB2007/053244 WO2008020405A2 (en) 2006-08-15 2007-08-15 Azetidine compounds as orexin receptor antagonists

Publications (1)

Publication Number Publication Date
PL2069332T3 true PL2069332T3 (pl) 2011-07-29

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PL07826034T PL2069332T3 (pl) 2006-08-15 2007-08-15 Związki azetydynowe jako antagoniści receptorów oreksynowych

Country Status (15)

Country Link
US (1) US7994336B2 (pl)
EP (1) EP2069332B1 (pl)
JP (1) JP2010500401A (pl)
KR (1) KR101113626B1 (pl)
CN (1) CN101506199A (pl)
AT (1) ATE500250T1 (pl)
AU (1) AU2007285371A1 (pl)
BR (1) BRPI0715893A2 (pl)
CA (1) CA2659299A1 (pl)
DE (1) DE602007012910D1 (pl)
ES (1) ES2360376T3 (pl)
MX (1) MX2009001432A (pl)
PL (1) PL2069332T3 (pl)
RU (1) RU2447070C2 (pl)
WO (1) WO2008020405A2 (pl)

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WO2008038251A2 (en) * 2006-09-29 2008-04-03 Actelion Pharmaceuticals Ltd 3-aza-bicyclo[3.1.0]hexane derivatives
ES2357992T3 (es) 2006-12-01 2011-05-04 Actelion Pharmaceuticals Ltd. Derivados de 3-heteroaril(amino o amido)-1-(bifenil o feniltiazolil)carbonilpiperidina como inhibidores del receptor de orexina.
AR064561A1 (es) * 2006-12-28 2009-04-08 Actelion Pharmaceuticals Ltd Derivados de 2-aza-biciclo[3.1.0]hexano y su uso en la preparacion de un medicamento para el tratamiento de enfermedades relacionadas con disfunciones generales del sistema de la orexina.
CL2008000836A1 (es) * 2007-03-26 2008-11-07 Actelion Pharmaceuticals Ltd Compuestos derivados de tiazolidina, antagonistas del receptor de orexina; composicion farmaceutica que los comprende; y su uso en el tratamiento de neurosis emocional, depresion grave, trastornos psicoticos, alzheimer, parkinson, dolor, entre otras.
EP2152690B1 (en) 2007-05-23 2012-01-11 Merck Sharp & Dohme Corp. Pyridyl piperidine orexin receptor antagonists
JP2010531871A (ja) * 2007-07-03 2010-09-30 アクテリオン ファーマシューティカルズ リミテッド ３−アザ−ビシクロ［３．３．０］オクタン化合物
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
EP2207778A2 (en) * 2007-09-24 2010-07-21 Actelion Pharmaceuticals Ltd. Pyrrolidines and piperidines as orexin receptor antagonists
ES2385699T3 (es) * 2008-02-21 2012-07-30 Actelion Pharmaceuticals Ltd. Derivados de 2-aza-biciclo-[2,2,1]heptano
EP2318367B1 (en) * 2008-04-30 2013-03-20 Actelion Pharmaceuticals Ltd. Piperidine and pyrrolidine compounds
EP2161266A1 (en) 2008-08-22 2010-03-10 EVOTEC Neurosciences GmbH Benzofuran derivatives as orexin receptor antagonists
AU2009305005A1 (en) * 2008-10-14 2010-04-22 Actelion Pharmaceuticals Ltd Phenethylamide derivatives and their heterocyclic analogues
US8796297B2 (en) 2009-06-30 2014-08-05 Abbvie Inc. 4-substituted-2-amino-pyrimidine derivatives
PL2491038T3 (pl) 2009-10-23 2016-10-31 Dwupodstawione oktahydropirolo[3,4-c]pirole jako modulatory receptora oreksyny
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RU2447070C2 (ru) 2012-04-10
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