MY153871A - Isoprene synthase variants for improved microbial production of isoprene - Google Patents

Isoprene synthase variants for improved microbial production of isoprene

Info

Publication number
MY153871A
MY153871A MYPI2010004990A MYPI20104990A MY153871A MY 153871 A MY153871 A MY 153871A MY PI2010004990 A MYPI2010004990 A MY PI2010004990A MY PI20104990 A MYPI20104990 A MY PI20104990A MY 153871 A MY153871 A MY 153871A
Authority
MY
Malaysia
Prior art keywords
isoprene
present
microbial production
synthase variants
improved microbial
Prior art date
Application number
MYPI2010004990A
Other languages
English (en)
Inventor
Marguerite A Cervin
James T Kellis
Gregory M Whited
Miasnikov Andrei
Caroline M Peres
Weyler Walter
Derek H Wells
Richard R Bott
Rife Christopher Lee
Joseph C Mcauliffe
Original Assignee
Danisco Us Inc
Goodyear Tire & Rubber
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc, Goodyear Tire & Rubber filed Critical Danisco Us Inc
Publication of MY153871A publication Critical patent/MY153871A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/25—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving enzymes not classifiable in groups C12Q1/26 - C12Q1/66
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03027—Isoprene synthase (4.2.3.27)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
MYPI2010004990A 2008-04-23 2009-04-23 Isoprene synthase variants for improved microbial production of isoprene MY153871A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12533608P 2008-04-23 2008-04-23

Publications (1)

Publication Number Publication Date
MY153871A true MY153871A (en) 2015-03-31

Family

ID=40810540

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2010004990A MY153871A (en) 2008-04-23 2009-04-23 Isoprene synthase variants for improved microbial production of isoprene

Country Status (14)

Country Link
US (3) US8173410B2 (enExample)
EP (1) EP2279251A2 (enExample)
JP (2) JP2011518564A (enExample)
KR (1) KR20110020234A (enExample)
CN (1) CN102171335A (enExample)
AU (1) AU2009240505B2 (enExample)
BR (1) BRPI0911667A2 (enExample)
CA (1) CA2722440A1 (enExample)
MX (1) MX2010011706A (enExample)
MY (1) MY153871A (enExample)
RU (2) RU2516343C2 (enExample)
SG (2) SG192545A1 (enExample)
WO (1) WO2009132220A2 (enExample)
ZA (2) ZA201007564B (enExample)

Families Citing this family (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101772570B (zh) * 2007-06-08 2015-03-18 丹尼斯科美国公司 异源和同源纤维素酶表达体系
BRPI0823506A8 (pt) 2007-12-13 2018-05-15 Danisco Us Inc Genencor Div composições e métodos para a produção de isoprene
JP2011518564A (ja) * 2008-04-23 2011-06-30 ダニスコ・ユーエス・インク 改良された微生物によるイソプレン産出用のイソプレンシンターゼ変異体
SG167485A1 (en) * 2008-06-30 2011-01-28 Danisco Us Inc Polymers of isoprene from renewable resources
CA2737082A1 (en) * 2008-09-15 2010-03-18 Danisco Us Inc. Increased isoprene production using mevalonate kinase and isoprene synthase
CA2737223A1 (en) * 2008-09-15 2010-03-18 Danisco Us Inc. Reduction of carbon dioxide emission during isoprene production by fermentation
MY156562A (en) 2008-09-15 2016-02-26 Danisco Us Inc Increased isoprene production using the archaeal lower mevalonate pathway
BRPI1015250B1 (pt) 2009-04-02 2019-04-24 Amyris, Inc. Métodos de estabilização e de hidrogenação para olefinas micróbio-derivadas
EP2421966A2 (en) * 2009-04-23 2012-02-29 Danisco US Inc. Three-dimensional structure of isoprene synthase and its use thereof for generating variants
TW201120213A (en) 2009-06-17 2011-06-16 Danisco Us Inc Polymerization of isoprene from renewable resources
TW201412988A (zh) 2009-06-17 2014-04-01 Danisco Us Inc 使用ｄｘｐ及ｍｖａ途徑之改良之異戊二烯製造
TWI434921B (zh) 2009-06-17 2014-04-21 Danisco Us Inc 從生物異戊二烯組合物製造燃料成分之方法及系統
US20110039323A1 (en) * 2009-08-14 2011-02-17 Eric Lawrence Singsaas Isoprene Production
CA2785530A1 (en) 2009-12-22 2011-06-23 Danisco Us Inc. Membrane bioreactor for increased production of isoprene gas
AU2010336342B2 (en) 2009-12-23 2015-02-26 Danisco Us Inc. Compositions and methods for the increased production of isoprene and other products with 6 - phosphogluconolactonase (PGL)
MX336229B (es) * 2010-05-05 2016-01-08 Genomatica Inc Microorganismos y metodos para la biosintesis de butadieno.
US20130158106A1 (en) * 2010-06-02 2013-06-20 The United States Of America As Represented By The Department Of Veteran Affairs Tocopherol derivatives and methods of use
BR112012032276A2 (pt) 2010-06-17 2016-11-16 Danisco Us Inc composições de combustível compreendendo derivados de isopreno
WO2012019169A1 (en) 2010-08-06 2012-02-09 Danisco Us Inc. Production of isoprene under neutral ph conditions
EP2444415A1 (en) * 2010-10-20 2012-04-25 Genoplante-Valor 1-Deoxy-D-xylulose 5-phosphate synthase alleles responsible for enhanced terpene biosynthesis
JP2014502148A (ja) * 2010-10-27 2014-01-30 ダニスコ・ユーエス・インク イソプレン生産の向上を目的としたイソプレン合成酵素変異体
EP2655606A1 (en) 2010-12-22 2013-10-30 Danisco US Inc. Compositions and methods for improved isoprene production using two types of ispg enzymes
WO2012088450A1 (en) 2010-12-22 2012-06-28 Danisco Us Inc. Biological production of pentose sugars using recombinant cells
MX348334B (es) 2011-02-02 2017-06-07 Genomatica Inc Microorganismo y metodos para la biosintesis de butadieno.
MX346518B (es) 2011-02-02 2017-03-23 Amyris Inc Metodos de desarrollo de variantes de terpeno sintasa.
US9121038B2 (en) 2011-04-29 2015-09-01 The Goodyear Tire & Rubber Company Recombinant microorganisms for enhanced production of mevalonate, isoprene, and isoprenoids
JP2014519811A (ja) 2011-04-29 2014-08-21 ダニスコ・ユーエス・インク チオラーゼ、ＨＭＧ−ＣｏＡ合成酵素及びＨＭＧ−ＣｏＡ還元酵素活性を有するポリペプチドをコードしている遺伝子を使用するメバロン酸、イソプレン、及びイソプレノイドの生産
US9169486B2 (en) 2011-06-22 2015-10-27 Genomatica, Inc. Microorganisms for producing butadiene and methods related thereto
WO2013016591A1 (en) * 2011-07-26 2013-01-31 Zuvachem, Inc. High efficiency isoprene synthases produced by protein engineering
AU2012289886A1 (en) 2011-08-04 2014-02-20 Danisco Us Inc. Production of isoprene, isoprenoid precursors, and isoprenoids using acetoacetyl-CoA synthase
US8951764B2 (en) 2011-08-05 2015-02-10 Danisco Us Inc. Production of isoprenoids under neutral pH conditions
WO2013040383A1 (en) 2011-09-16 2013-03-21 Genomatica, Inc. Microorganisms and methods for producing alkenes
SG11201401249PA (en) 2011-10-07 2014-05-29 Danisco Us Inc Utilization of phosphoketolase in the production of mevalonate, isoprenoid precursors, and isoprene
WO2013063528A2 (en) 2011-10-27 2013-05-02 Danisco Us Inc. Isoprene synthase variants with improved solubility for production of isoprene
US8975051B2 (en) 2011-12-23 2015-03-10 Danisco Us Inc. Enhanced production of isoprene using host cells having decreased ispA activity
EP2794876A1 (en) 2011-12-23 2014-10-29 Danisco US Inc. Production of isoprene under reduced oxygen inlet levels
EP2794851A2 (en) * 2011-12-23 2014-10-29 Danisco US Inc. Enhanced production of isoprene using marine bacterial cells
WO2013130481A1 (en) * 2012-03-02 2013-09-06 Codexis, Inc. Recombinant host cells and processes for producing 1,3-butadiene through a crotonol intermediate
US9315831B2 (en) 2012-03-30 2016-04-19 Danisco Us Inc. Direct starch to fermentable sugar as feedstock for the production of isoprene, isoprenoid precursor molecules, and/or isoprenoids
US8895277B2 (en) 2012-05-02 2014-11-25 Danisco Us Inc. Legume isoprene synthase for production of isoprene
US9163263B2 (en) 2012-05-02 2015-10-20 The Goodyear Tire & Rubber Company Identification of isoprene synthase variants with improved properties for the production of isoprene
US8962296B2 (en) 2012-05-30 2015-02-24 Bridgestone Corporation Isoprene synthase and gene encoding the same, and method for producing isoprene monomer
JP6169073B2 (ja) * 2012-05-30 2017-07-26 株式会社ブリヂストン イソプレンシンターゼおよびそれをコードするポリヌクレオチド、ならびにイソプレンモノマーの製造方法
WO2013181647A2 (en) 2012-06-01 2013-12-05 Danisco Us Inc. Compositions and methods of producing isoprene and/or industrrial bio-products using anaerobic microorganisms
US9382554B2 (en) 2012-07-27 2016-07-05 Wisys Technology Foundation, Inc. Methods for isoprene and pinene production in cyanobacteria
CN111621453A (zh) 2012-10-23 2020-09-04 积水化学工业株式会社 重组细胞以及异戊二烯的生产方法
WO2014066892A1 (en) * 2012-10-26 2014-05-01 Coelho Pedro S De novo metabolic pathways for isoprene biosynthesis
BR112015014843A2 (pt) 2012-12-21 2017-10-10 Danisco Us Inc produção de isopreno, isoprenoide, e precursores de isoprenoide usando uma via de mevalonato inferior alternativa
US9695447B2 (en) 2012-12-27 2017-07-04 Sekisui Chemical Co., Ltd. Recombinant cell and method for producing isoprene
US9175330B2 (en) * 2013-02-20 2015-11-03 Korea Research Institute Of Bioscience And Biotechnology Method for screening and quantifying isoprene biosynthesis enzyme activity
EP2971021A4 (en) 2013-03-15 2016-12-21 Genomatica Inc MICROORGANISMS AND METHOD FOR THE PRODUCTION OF BUTADIENE AND RELATED COMPOUNDS BY FORMATASSIMILATION
US9850512B2 (en) 2013-03-15 2017-12-26 The Research Foundation For The State University Of New York Hydrolysis of cellulosic fines in primary clarified sludge of paper mills and the addition of a surfactant to increase the yield
ES2735331T3 (es) 2013-04-10 2019-12-18 Goodyear Tire & Rubber Fosfocetolasas para mejorar la producción de metabolitos derivados de acetil-coenzima A, isopreno, precursores de isoprenoides e isoprenoides
CN103215315B (zh) * 2013-04-15 2015-05-20 上海工业生物技术研发中心 利用蓝藻生产异戊二烯
ES2728307T3 (es) 2013-06-21 2019-10-23 Danisco Us Inc Composiciones y métodos para la transformación clostridial
CA2916759C (en) 2013-08-08 2023-02-28 Knipbio Methylotrophs for aquaculture and animal feed
KR20160068776A (ko) 2013-09-13 2016-06-15 더 보드 오브 트러스티스 오브 더 유니버시티 오브 아칸소 방사선 효과의 완화 및 예방을 위한 조성물의 제조 및 용도
MY172689A (en) 2013-11-22 2019-12-10 Ajinomoto Kk Modified isoprene synthase
EP3075843B1 (en) 2013-11-28 2019-07-03 Ajinomoto Co., Inc. Method for producing isoprene monomer
PL3077501T3 (pl) 2013-12-03 2022-01-31 Genomatica, Inc. Mikroorganizmy i sposoby poprawy wydajności produktu na metanolu z użyciem syntezy acetylo-coa
US10648004B2 (en) 2014-02-20 2020-05-12 Danisco Us Inc. Recombinant microorganisms for the enhanced production of mevalonate, isoprene, isoprenoid precursors, isoprenoids, and acetyl-CoA-derived products
US9951363B2 (en) 2014-03-14 2018-04-24 The Research Foundation for the State University of New York College of Environmental Science and Forestry Enzymatic hydrolysis of old corrugated cardboard (OCC) fines from recycled linerboard mill waste rejects
RU2014112066A (ru) 2014-03-28 2015-10-10 Адзиномото Ко., Инк. Способ получения мономерного изопрена
WO2016004334A1 (en) 2014-07-03 2016-01-07 Genomatica, Inc. Microorganisms for producing 4c-5c compounds with unsaturation and methods related thereto
KR101582259B1 (ko) 2014-07-04 2016-01-04 명지대학교 산학협력단 이소프렌을 생산하는 대장균 균주 fmis2 및 이의 용도
WO2016015021A1 (en) 2014-07-24 2016-01-28 The Regents Of The University Of California Oxidative starch degradation by a new family of pmos
KR102330593B1 (ko) * 2014-07-28 2021-11-26 에스케이이노베이션 주식회사 신규 이소프렌 신타아제 및 이를 이용한 이소프렌의 제조방법
RO130063A8 (ro) 2014-08-28 2017-06-30 Romvac Company S.A. Producerea şi utilizarea ovotransferinei moderne ()
EP3741865B1 (en) 2014-09-18 2024-03-13 Genomatica, Inc. Non-natural microbial organisms with improved energetic efficiency
CN105985977B (zh) * 2015-02-10 2020-12-25 中国科学院微生物研究所 异戊二烯合成酶基因及其应用
CN105985976A (zh) * 2015-02-10 2016-10-05 中国科学院微生物研究所 异戊二烯合成酶基因及其应用
CN105985972A (zh) * 2015-02-10 2016-10-05 中国科学院微生物研究所 异戊二烯合成酶基因及其应用
CN105985973A (zh) * 2015-02-10 2016-10-05 中国科学院微生物研究所 异戊二烯合成酶基因及其应用
CN105985975A (zh) * 2015-02-10 2016-10-05 中国科学院微生物研究所 异戊二烯合成酶基因及其应用
WO2016129637A1 (ja) * 2015-02-13 2016-08-18 積水化学工業株式会社 核酸、融合タンパク質、組換え細胞、並びに、イソプレン又は環式テルペンの生産方法
US20160324914A1 (en) 2015-05-05 2016-11-10 Tocol Pharmaceuticals, Llc Use of rice bran oil distillate extract for prevention and mitigation of the effects of radiation
KR102546640B1 (ko) * 2016-01-26 2023-06-22 에스케이이노베이션 주식회사 재조합 호염성 메탄균주를 이용한 이소프렌의 제조방법
CN107991399B (zh) * 2016-10-27 2022-03-08 天士力医药集团股份有限公司 一种同时测定复方丹参提取物或相关药材中31种成分的方法
JP2020513790A (ja) 2017-02-06 2020-05-21 ザイマージェン インコーポレイテッド 発酵によりチラミンを生成させるための遺伝子操作型生合成経路
CN117402799A (zh) 2017-02-27 2024-01-16 积水化学工业株式会社 重组细胞、重组细胞的制备方法以及异戊二烯或萜烯的生产方法
EP3615667B1 (en) 2017-04-27 2021-08-11 The Regents of The University of California Microorganisms and methods for producing cannabinoids and cannabinoid derivatives
CN111032855A (zh) * 2017-06-01 2020-04-17 尼普生物股份有限公司 微生物体中异源类胡萝卜素的产生
US11634733B2 (en) 2017-06-30 2023-04-25 Inv Nylon Chemicals Americas, Llc Methods, materials, synthetic hosts and reagents for the biosynthesis of hydrocarbons and derivatives thereof
WO2019006257A1 (en) * 2017-06-30 2019-01-03 Invista North America .S.A.R.L. METHODS, SYNTHETIC HOSTS AND REAGENTS FOR HYDROCARBON BIOSYNTHESIS
US11452967B2 (en) 2017-07-17 2022-09-27 Zymergen Inc. Metal-organic framework materials
KR101965210B1 (ko) * 2017-09-26 2019-04-04 한국생명공학연구원 신규 이소프렌 합성 효소 및 이를 이용한 이소프렌 생산 방법
US11505809B2 (en) 2017-09-28 2022-11-22 Inv Nylon Chemicals Americas Llc Organisms and biosynthetic processes for hydrocarbon synthesis
WO2019156717A2 (en) 2017-10-05 2019-08-15 Zymergen Inc. Optically transparent polyimides
CA3084263A1 (en) 2017-12-07 2019-06-13 Zymergen Inc. Engineered biosynthetic pathways for production of (6e)-8-hydroxygeraniol by fermentation
CN111868047A (zh) 2017-12-21 2020-10-30 齐默尔根公司 荆芥内半缩醛氧化还原酶、荆芥内半缩醛合酶和能够产生荆芥内酯的微生物
WO2020069142A1 (en) 2018-09-26 2020-04-02 Demetrix, Inc. Optimized expression systems for expressing berberine bridge enzyme and berberine bridge enzyme-like polypeptides
WO2020071538A1 (en) 2018-10-05 2020-04-09 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
SG11202111975UA (en) 2019-05-22 2021-11-29 Demetrix Inc Optimized cannabinoid synthase polypeptides
CN110241103B (zh) * 2019-07-04 2021-01-19 江西邦泰绿色生物合成生态产业园发展有限公司 一种生物酶法生产异戊二烯的方法
BR112022004797A2 (pt) 2019-09-18 2022-06-21 Demetrix Inc Polipeptídeos otimizados de ácido tetra-hidrocanabinólico (thca) sintase
WO2021183448A1 (en) 2020-03-09 2021-09-16 Demetrix, Inc. Optimized olivetolic acid cyclase polypeptides
WO2024259559A1 (en) 2023-06-19 2024-12-26 Hangzhou Enhe Biotechnology Co., Ltd. Fusion polypeptides for production of 7-dehydrocholesterol and methods of use thereof

Family Cites Families (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1344713A (en) * 1915-12-02 1920-06-29 Westinghouse Electric & Mfg Co Reactance-coil
DE1793254A1 (de) * 1968-08-23 1971-12-16 Bayer Ag Verfahren zur Gewinnung von Cyclopenten,Isopren und einem Diolefinstrom aus C?-Crackbenzinschnitten
US5380831A (en) * 1986-04-04 1995-01-10 Mycogen Plant Science, Inc. Synthetic insecticidal crystal protein gene
DE3338269A1 (de) * 1983-10-21 1985-05-02 Basf Ag, 6700 Ludwigshafen Verfahren zur gewinnung von isopren aus einem c(pfeil abwaerts)5(pfeil abwaerts)-kohlenwasserstoffgemisch
GB8407828D0 (en) * 1984-03-27 1984-05-02 Ontario Research Foundation In situ preparation
US4570029A (en) * 1985-03-04 1986-02-11 Uop Inc. Process for separating isoprene
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4965188A (en) * 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
AU607398B2 (en) 1985-08-29 1991-03-07 Genencor Inc. Heterologous polypeptides expressed in filamentous fungi, processes for making same, and vectors for making same
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
GB8610600D0 (en) 1986-04-30 1986-06-04 Novo Industri As Transformation of trichoderma
US4846872A (en) * 1986-08-11 1989-07-11 Fujisawa Pharmaceutical Co., Ltd. Herbicide
US5322770A (en) * 1989-12-22 1994-06-21 Hoffman-Laroche Inc. Reverse transcription with thermostable DNA polymerases - high temperature reverse transcription
US5545816A (en) * 1990-03-02 1996-08-13 Amoco Corporation Phytoene biosynthesis in genetically engineered hosts
US5306862A (en) * 1990-10-12 1994-04-26 Amoco Corporation Method and composition for increasing sterol accumulation in higher plants
DK1225227T3 (da) * 1990-12-10 2009-06-22 Genencor Int Forbedret forsukring af cellulose ved kloning og amplifikation af beta-glucosidase genet af trichoderma
TW261517B (enExample) * 1991-11-29 1995-11-01 Mitsubishi Shozi Kk
WO1995004134A1 (en) 1993-08-02 1995-02-09 Genencor International, Inc. Method of reducing complex carbohydrates in fermentation products
CA2118071C (en) 1993-10-28 2004-09-14 Rodney B. Croteau Dna encoding limonene synthase from mentha spicata
US5861271A (en) * 1993-12-17 1999-01-19 Fowler; Timothy Cellulase enzymes and systems for their expressions
US5686276A (en) 1995-05-12 1997-11-11 E. I. Du Pont De Nemours And Company Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
US5849970A (en) * 1995-06-23 1998-12-15 The Regents Of The University Of Colorado Materials and methods for the bacterial production of isoprene
US8106260B2 (en) * 1996-04-12 2012-01-31 The Board Of Trustees Of The University Of Kentucky Chimeric isoprenoid synthases and uses thereof
DE19629568C1 (de) 1996-07-15 1998-01-08 Fraunhofer Ges Forschung Verfahren zur Herstellung von Isopren
CA2278523C (en) * 1997-01-17 2013-06-18 The Scripps Research Institute Rna binding protein and binding site useful for expression of recombinant molecules
KR100657388B1 (ko) * 1998-04-14 2006-12-13 교와 학꼬 고교 가부시키가이샤 미생물에 의한 이소프레노이드 화합물의 제조 방법
US6176176B1 (en) * 1998-04-30 2001-01-23 Board Of Trustees Operating Michigan State University Apparatus for treating cellulosic materials
AR022383A1 (es) 1998-09-18 2002-09-04 Univ Kentucky Res Found Sintasas
US6268328B1 (en) * 1998-12-18 2001-07-31 Genencor International, Inc. Variant EGIII-like cellulase compositions
US6442536B1 (en) 2000-01-18 2002-08-27 Praxair Technology, Inc. Method for predicting flammability limits of complex mixtures
WO2001058839A1 (en) 2000-02-07 2001-08-16 Eastman Chemical Company Process to recover condensable gases from oxygen containing mixtures
KR20010084864A (ko) 2000-02-29 2001-09-06 김수언 개똥쑥의 아모파-4,11-디엔 합성효소, 이를 코딩하는유전자, 이 유전자를 포함하는 발현벡터 및, 이발현벡터로 형질전환된 대장균 및 식물체
US6270739B1 (en) * 2000-06-16 2001-08-07 Eastman Chemical Company Process for the removal of carbon dioxide from 3,4-epoxy-1-butene process recycle streams
US20030033626A1 (en) * 2000-07-31 2003-02-13 Hahn Frederick M. Manipulation of genes of the mevalonate and isoprenoid pathways to create novel traits in transgenic organisms
AU2001286528A1 (en) * 2000-08-18 2002-03-04 Integrigen, Inc. Methods and compositions for directed molecular evolution using DNA-end modification
US6553689B2 (en) * 2000-09-24 2003-04-29 3M Innovative Properties Company Vapor collection method and apparatus
US6582914B1 (en) * 2000-10-26 2003-06-24 Genencor International, Inc. Method for generating a library of oligonucleotides comprising a controlled distribution of mutations
AU2002233614B2 (en) 2001-03-22 2007-05-24 Scentgene Pollination Ltd. Method of enhancing entomophilous
DE60230971D1 (de) * 2001-04-04 2009-03-12 Genencor Int Entkoppelte anabole und katabole stoffwechselwege in wirtszellen
RU2197461C2 (ru) * 2001-04-05 2003-01-27 Общество с ограниченной ответственностью "Еврохим-СПб-Трейдинг" Способ получения изопрена
AU2002316966B2 (en) * 2001-06-06 2007-05-17 Dsm Ip Assets B.V. Improved isoprenoid production
US6998471B2 (en) 2001-07-25 2006-02-14 E.I. Du Pont De Nemours And Company Polynucleotides encoding an acetyl-CoA acetyltransferase from Hevea brasiliensis, related products, and methods
US7192751B2 (en) * 2001-12-06 2007-03-20 The Regents Of The University Of California Biosynthesis of amorpha-4,11-diene
US7172886B2 (en) * 2001-12-06 2007-02-06 The Regents Of The University Of California Biosynthesis of isopentenyl pyrophosphate
CA2481414C (en) 2002-04-22 2013-04-09 E.I. Du Pont De Nemours And Company Promoter and plasmid system for genetic engineering
US20050287655A1 (en) * 2002-05-10 2005-12-29 Kyowa Hakko Kogyo Co., Ltd. Process for producing mevalonic acid
AU2003287028B2 (en) 2002-10-04 2008-09-04 E.I. Du Pont De Nemours And Company Process for the biological production of 1,3-propanediol with high yield
US20040219629A1 (en) * 2002-12-19 2004-11-04 Qiong Cheng Increasing carotenoid production in bacteria via chromosomal integration
FR2850101B1 (fr) * 2003-01-22 2007-03-02 Michelin Soc Tech Procede d'obtention d'une coupe c5 "fcc" enrichie en isoprene et polymerisation selective de l'isoprene a partir de cette coupe
DK1862539T3 (da) 2003-05-29 2012-05-14 Danisco Us Inc Nye trichodermagener
KR101190897B1 (ko) 2003-06-12 2012-10-12 디에스엠 아이피 어셋츠 비.브이. 피드백 내성 메발로네이트 키나아제
PL202927B1 (pl) 2003-07-20 2009-08-31 Carr Daniel R Peptyd i kompozycja farmaceutyczna oraz ich zastosowania medyczne
ATE550424T1 (de) * 2003-11-21 2012-04-15 Danisco Us Inc Expression granuläre stärke hydrolysierender enzyme in trichoderma und verfahren zur herstellung von glucose aus granulären stärkesubstraten
US20070281332A1 (en) 2004-02-13 2007-12-06 Allan Svendsen Protease Variants
ES2379368T3 (es) * 2004-05-21 2012-04-25 The Regents Of The University Of California Método para aumentar la producción de compuestos isoprenoides
CN100572370C (zh) * 2004-06-18 2009-12-23 国际壳牌研究有限公司 生产烯烃氧化物、1,2-二醇、1,2-二醇醚或链烷醇胺的方法
WO2006063752A1 (en) 2004-12-14 2006-06-22 Dsm Ip Assets B.V. Improved mevalonate kinase
JP4117350B2 (ja) * 2005-03-03 2008-07-16 富山県 機能改変フェニルアラニン脱水素酵素、およびこの酵素を用いた生体試料中のアミノ酸の分析方法
JP4446482B2 (ja) 2005-08-10 2010-04-07 独立行政法人産業技術総合研究所 ユーカリ・モノテルペン合成酵素遺伝子
WO2007093962A2 (en) * 2006-02-14 2007-08-23 Firmenich Sa Method for producing terpenes and mep-transformed microorganisms therefore
US8114645B2 (en) 2006-05-19 2012-02-14 The Regents Of The University Of California Methods for increasing isoprenoid and isoprenoid precursor production by modulating fatty acid levels
CA2651747C (en) * 2006-05-26 2017-10-24 Amyris Biotechnologies, Inc. Production of isoprenoids
EP2032698B1 (en) 2006-06-23 2012-06-27 Danisco US Inc. Systematic evaluation of sequence and activity relationships using site evaluation libraries for engineering multiple properties
US7947478B2 (en) * 2006-06-29 2011-05-24 The Regents Of The University Of California Short chain volatile hydrocarbon production using genetically engineered microalgae, cyanobacteria or bacteria
JP2008035831A (ja) 2006-08-09 2008-02-21 Nitta Ind Corp 有用部分の生産性が高められた植物及びその作製方法
JP4986547B2 (ja) 2006-09-04 2012-07-25 株式会社Ａｄｅｋａ 新規なアセトアセチルＣｏＡ合成酵素、それをコードするＤＮＡ配列、当該酵素の製造方法および当該酵素を利用したメバロン酸の製造方法
JP2008182950A (ja) 2007-01-30 2008-08-14 Hamamatsu Kagaku Gijutsu Kenkyu Shinkokai 柑橘類酵素遺伝子調製方法
CN101784653A (zh) * 2007-05-01 2010-07-21 嗜酸细胞有限责任公司 利用代谢改造的光合微生物将二氧化碳直接转化为烃的方法
JP5594895B2 (ja) 2007-06-06 2014-09-24 ダニスコ・ユーエス・インク、ジェネンコー・ディビジョン タンパク質の能力の改良方法
NZ598302A (en) 2007-09-11 2013-08-30 Sapphire Energy Inc Molecule production by photosynthetic organisms
BRPI0823506A8 (pt) * 2007-12-13 2018-05-15 Danisco Us Inc Genencor Div composições e métodos para a produção de isoprene
WO2009100231A2 (en) 2008-02-06 2009-08-13 The Regents Of The University Of California Short chain volatile isoprene hydrocarbon production using the mevalonic acid pathway in genetically engineered yeast and fungi
JP2009207402A (ja) 2008-03-04 2009-09-17 Shizuokaken Koritsu Daigaku Hojin 組換えサビネン合成酵素及びその利用
JP2011518564A (ja) * 2008-04-23 2011-06-30 ダニスコ・ユーエス・インク 改良された微生物によるイソプレン産出用のイソプレンシンターゼ変異体
SG167485A1 (en) 2008-06-30 2011-01-28 Danisco Us Inc Polymers of isoprene from renewable resources
EP2310490B1 (en) * 2008-07-02 2019-01-02 Danisco US Inc. Methods for producing isoprene
CA2737082A1 (en) 2008-09-15 2010-03-18 Danisco Us Inc. Increased isoprene production using mevalonate kinase and isoprene synthase
WO2010031079A1 (en) 2008-09-15 2010-03-18 Danisco Us Inc. Systems using cell culture for production of isoprene
BRPI0918936A2 (pt) * 2008-09-15 2019-09-24 Danisco Us Inc conversão de derivados de prenila em isopreno
MY156562A (en) 2008-09-15 2016-02-26 Danisco Us Inc Increased isoprene production using the archaeal lower mevalonate pathway
CA2737223A1 (en) 2008-09-15 2010-03-18 Danisco Us Inc. Reduction of carbon dioxide emission during isoprene production by fermentation
CN102333866B (zh) 2008-12-30 2015-04-29 丹尼斯科美国公司 生产异戊二烯和共同产物的方法
EP2421966A2 (en) 2009-04-23 2012-02-29 Danisco US Inc. Three-dimensional structure of isoprene synthase and its use thereof for generating variants
JP4760951B2 (ja) 2009-05-08 2011-08-31 トヨタ自動車株式会社 ブタノール生産能を有する組換え微生物及びブタノールの製造方法
TW201412988A (zh) 2009-06-17 2014-04-01 Danisco Us Inc 使用ｄｘｐ及ｍｖａ途徑之改良之異戊二烯製造
CA2766810C (en) 2009-06-29 2017-10-10 The University Of Western Australia Terpene synthases from santalum
JP2014502148A (ja) 2010-10-27 2014-01-30 ダニスコ・ユーエス・インク イソプレン生産の向上を目的としたイソプレン合成酵素変異体

Also Published As

Publication number Publication date
AU2009240505A1 (en) 2009-10-29
AU2009240505A2 (en) 2010-11-25
WO2009132220A9 (en) 2010-05-06
RU2010147659A (ru) 2012-05-27
RU2516343C2 (ru) 2014-05-20
ZA201007564B (en) 2012-01-25
BRPI0911667A2 (pt) 2019-04-24
US8916370B2 (en) 2014-12-23
ZA201108569B (en) 2014-10-29
CA2722440A1 (en) 2009-10-29
CN102171335A (zh) 2011-08-31
EP2279251A2 (en) 2011-02-02
AU2009240505B2 (en) 2013-09-05
KR20110020234A (ko) 2011-03-02
US8173410B2 (en) 2012-05-08
JP2011518564A (ja) 2011-06-30
SG165884A1 (en) 2010-11-29
US20100003716A1 (en) 2010-01-07
US20150191712A1 (en) 2015-07-09
WO2009132220A2 (en) 2009-10-29
JP2014158489A (ja) 2014-09-04
MX2010011706A (es) 2011-03-15
RU2014108776A (ru) 2015-09-20
WO2009132220A3 (en) 2010-01-21
SG192545A1 (en) 2013-08-30
US20130260432A1 (en) 2013-10-03

Similar Documents

Publication Publication Date Title
MY153871A (en) Isoprene synthase variants for improved microbial production of isoprene
WO2012058494A3 (en) Isoprene synthase variants for improved production of isoprene
MY187676A (en) Microorganisms for the production of 1,4-butanediol and related methods
WO2010030711A3 (en) Microorganisms for the production of 1,4-butanediol
WO2009135074A3 (en) Microorganisms for the production of methacrylic acid
WO2010124146A3 (en) Three-dimensional structure of isoprene synthase and its use thereof for generating variants
EP4413994A3 (en) Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof
UA103364C2 (ru) Способ ферментативного производства четырехатомных спиртов
SG196782A1 (en) Compositions and methods for the increased production of isoprene and other products with 6 - phosphogluconolactonase (pgl)
PH12012500729A1 (en) Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-coa, putrescine and related compounds and methods related thereto
WO2010111344A3 (en) Methods and microorganisms for production of c4-dicarboxylic acids
WO2013022881A8 (en) Compositions and methods for the biosynthesis of vanillin or vanillin beta-d-glucoside
IN2012DN03825A (enExample)
IN2012DN02878A (enExample)
IN2012DN00568A (enExample)
EP4559918A3 (en) Glucosylceramide synthase inhibitors
EP4032538A3 (en) Methods and products for in vivo enzyme profiling
MX341838B (es) Producción de una n-acetilgalactosamina-6-sulfatasa humana activa altamente fosforilada y sus usos.
MY182946A (en) Production of organic acids by fermentation at low ph
EA201171364A1 (ru) Ферментный комплекс
WO2011005289A3 (en) Methods and kits for measuring enzyme activity
MY197970A (en) Microorganisms and methods for the production of caprolactone
WO2012177983A3 (en) Microorganisms for producing ethylene glycol and methods related thereto
WO2010022194A3 (en) Compositions and methods for generation of pluripotent stem cells
WO2011021177A3 (en) Compositions and methods for prognosis and treatment of prostate cancer