MY142589A - Benzimidazole derivatives : preparation and pharmaceutical applications - Google Patents
Benzimidazole derivatives : preparation and pharmaceutical applicationsInfo
- Publication number
- MY142589A MY142589A MYPI20043871A MY142589A MY 142589 A MY142589 A MY 142589A MY PI20043871 A MYPI20043871 A MY PI20043871A MY 142589 A MY142589 A MY 142589A
- Authority
- MY
- Malaysia
- Prior art keywords
- preparation
- pharmaceutical applications
- benzimidazole derivatives
- compounds
- relates
- Prior art date
Links
- 229940058303 antinematodal benzimidazole derivative Drugs 0.000 title 1
- 125000003785 benzimidazolyl group Chemical class N1=C(NC2=C1C=CC=C2)* 0.000 title 1
- 102000003964 Histone deacetylase Human genes 0.000 abstract 3
- 108090000353 Histone deacetylase Proteins 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- HYZJCKYKOHLVJF-UHFFFAOYSA-N 1H-benzimidazole Chemical compound C1=CC=C2NC=NC2=C1 HYZJCKYKOHLVJF-UHFFFAOYSA-N 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000008482 dysregulation Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
Classifications
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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| TWI343377B (en) | 2002-03-13 | 2011-06-11 | Array Biopharma Inc | N3 alkylated benzimidazole derivatives as mek inhibitors |
| WO2003077855A2 (en) * | 2002-03-13 | 2003-09-25 | Array Biopharma, Inc | N3 alkylated benzimidazole derivatives as mek inhibitors |
| CA2484261A1 (en) * | 2002-04-16 | 2003-10-23 | Teijin Limited | Piperidine derivatives having ccr3 antagonism |
| DE10239042A1 (de) | 2002-08-21 | 2004-03-04 | Schering Ag | Makrozyclische Pyrimidine, deren Herstellung und Verwendung als Arzneimittel |
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| SMT202000168T1 (it) | 2012-10-30 | 2020-05-08 | Mei Pharma Inc | Terapie di combinazione per il trattamento dei tumori chemioresistenti |
-
2004
- 2004-09-21 KR KR20067005698A patent/KR101127201B1/ko not_active Expired - Fee Related
- 2004-09-21 DK DK04775628T patent/DK1673349T3/da active
- 2004-09-21 NZ NZ545864A patent/NZ545864A/en not_active IP Right Cessation
- 2004-09-21 DE DE200460027932 patent/DE602004027932D1/de not_active Expired - Lifetime
- 2004-09-21 AR ARP040103390 patent/AR046411A1/es active IP Right Grant
- 2004-09-21 AT AT04775628T patent/ATE472534T1/de active
- 2004-09-21 MY MYPI20043871 patent/MY142589A/en unknown
- 2004-09-21 TW TW093128611A patent/TWI349664B/zh not_active IP Right Cessation
- 2004-09-21 WO PCT/SG2004/000307 patent/WO2005028447A1/en not_active Ceased
- 2004-09-21 JP JP2006527948A patent/JP5042626B2/ja not_active Expired - Fee Related
- 2004-09-21 BR BRPI0414581A patent/BRPI0414581C1/pt not_active IP Right Cessation
- 2004-09-21 CA CA 2539766 patent/CA2539766C/en not_active Expired - Fee Related
- 2004-09-21 US US10/572,958 patent/US7781595B2/en not_active Expired - Fee Related
- 2004-09-21 PT PT04775628T patent/PT1673349E/pt unknown
-
2010
- 2010-06-14 US US12/814,964 patent/US8551988B2/en not_active Expired - Fee Related
-
2013
- 2013-09-03 US US14/016,990 patent/US9024029B2/en not_active Expired - Fee Related
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2015
- 2015-02-20 US US14/627,418 patent/US9402829B2/en not_active Expired - Fee Related
-
2016
- 2016-06-10 US US15/178,742 patent/US9717713B2/en not_active Expired - Fee Related
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2017
- 2017-06-02 US US15/612,670 patent/US10201527B2/en not_active Expired - Fee Related
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2018
- 2018-12-14 US US16/221,186 patent/US10736881B2/en not_active Expired - Fee Related
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