MY108350A - Novel acylals of imidazole-5-carboxylic acid derivative process for their preparation and their use. - Google Patents

Novel acylals of imidazole-5-carboxylic acid derivative process for their preparation and their use.

Info

Publication number
MY108350A
MY108350A MYPI92001717A MYPI19921717A MY108350A MY 108350 A MY108350 A MY 108350A MY PI92001717 A MYPI92001717 A MY PI92001717A MY PI19921717 A MYPI19921717 A MY PI19921717A MY 108350 A MY108350 A MY 108350A
Authority
MY
Malaysia
Prior art keywords
acylals
carboxylic acid
imidazole
novel
preparation
Prior art date
Application number
MYPI92001717A
Other languages
English (en)
Inventor
Dieter Binder Dr
Josef Wienberger Dr
Original Assignee
Chemisch Pharmazeutische
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemisch Pharmazeutische filed Critical Chemisch Pharmazeutische
Publication of MY108350A publication Critical patent/MY108350A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MYPI92001717A 1991-10-04 1992-09-25 Novel acylals of imidazole-5-carboxylic acid derivative process for their preparation and their use. MY108350A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0198791A AT398202B (de) 1991-10-04 1991-10-04 Neue imidazolderivate, verfahren zu ihrer herstellung und ihre verwendung

Publications (1)

Publication Number Publication Date
MY108350A true MY108350A (en) 1996-09-30

Family

ID=3525398

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI92001717A MY108350A (en) 1991-10-04 1992-09-25 Novel acylals of imidazole-5-carboxylic acid derivative process for their preparation and their use.

Country Status (22)

Country Link
US (1) US5298519A (ref)
EP (1) EP0535420A1 (ref)
JP (1) JP2544565B2 (ref)
CN (1) CN1032856C (ref)
AT (1) AT398202B (ref)
AU (1) AU649357B2 (ref)
CA (1) CA2079735A1 (ref)
CZ (1) CZ301992A3 (ref)
FI (1) FI924353L (ref)
HR (1) HRP920817A2 (ref)
HU (1) HUT62291A (ref)
IL (1) IL103329A (ref)
LV (1) LV10256B (ref)
MY (1) MY108350A (ref)
NO (1) NO923798L (ref)
NZ (1) NZ244320A (ref)
RU (1) RU2105764C1 (ref)
SI (1) SI9200240A (ref)
SK (1) SK301992A3 (ref)
TW (1) TW223073B (ref)
YU (1) YU48290B (ref)
ZA (1) ZA927205B (ref)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2105939B1 (es) * 1994-08-02 1998-07-01 Uriach & Cia Sa J Nuevos pirazoles con actividad antagonista de la angiotensina ii.
WO2005011646A2 (en) * 2003-07-31 2005-02-10 Nicox S.A. Nitrooxy derivatives of losartan, valsatan, candesartan, telmisartan, eprosartan and olmesartan as angiotensin-ii receptor blockers for the treatment of cardiovascular diseases
CN101024643A (zh) * 2006-02-20 2007-08-29 上海艾力斯医药科技有限公司 咪唑－5－羧酸类衍生物、制备方法及其应用
WO2008067687A1 (en) * 2006-12-06 2008-06-12 Shanghai Allist Pharmaceutical., Inc. The salts of imidazol-5-carboxylic acid derivatives, preparation methods and use therrof
CN101195615B (zh) * 2006-12-06 2013-03-27 深圳市信立泰资产管理有限公司 咪唑-5-羧酸衍生物的盐、制备方法及其药物组合物
CN101214242A (zh) * 2007-01-05 2008-07-09 上海艾力斯医药科技有限公司 新的药用组合物
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US7879802B2 (en) 2007-06-04 2011-02-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CN101317842A (zh) * 2007-06-07 2008-12-10 上海艾力斯医药科技有限公司 一种咪唑-5-羧酸衍生物的治疗用途
CN101367795B (zh) * 2007-08-17 2012-05-02 上海艾力斯生物医药有限公司 一种咪唑-5-羧酸衍生物及其制备方法
CN101407511B (zh) * 2007-10-11 2013-01-09 上海艾力斯生物医药有限公司 一种结晶型的咪唑-5-羧酸衍生物
AU2009256157B2 (en) 2008-06-04 2014-12-18 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
JP2011528375A (ja) 2008-07-16 2011-11-17 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CN103012377A (zh) * 2011-09-27 2013-04-03 江苏艾力斯生物医药有限公司 一种咪唑-5-羧酸酯的重结晶方法
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
JP2016514671A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
AU2014274812B2 (en) 2013-06-05 2018-09-27 Bausch Health Ireland Limited Ultra-pure agonists of guanylate cyclase C, method of making and using same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
US5064825A (en) * 1989-06-01 1991-11-12 Merck & Co., Inc. Angiotensin ii antagonists
WO1991000281A2 (en) * 1989-06-30 1991-01-10 E.I. Du Pont De Nemours And Company Fused-ring aryl substituted imidazoles
DE69013607T2 (de) * 1989-08-02 1995-03-02 Takeda Chemical Industries Ltd Pyrazol-Derivate, Verfahren zu deren Herstellung und Anwendung.
DE4132631A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Imidazolyl-propensaeurederivate
DE4132632A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Substituierte imidazolyl-propensaeurederivate
PT573218E (pt) * 1992-06-02 2001-06-29 Sankyo Co 4-carbonilimidazoles como antagonistas de angiotensina ii e sua utilizacao terapeutica

Also Published As

Publication number Publication date
IL103329A (en) 1996-10-31
YU87592A (sh) 1995-10-03
US5298519A (en) 1994-03-29
SI9200240A (en) 1993-06-30
AU2617692A (en) 1993-04-08
HUT62291A (en) 1993-04-28
JP2544565B2 (ja) 1996-10-16
ZA927205B (en) 1993-03-23
RU2105764C1 (ru) 1998-02-27
CN1032856C (zh) 1996-09-25
CZ301992A3 (en) 1993-08-11
LV10256B (en) 1995-04-20
FI924353A7 (fi) 1993-04-05
CA2079735A1 (en) 1993-04-05
AU649357B2 (en) 1994-05-19
YU48290B (sh) 1998-05-15
JPH05310731A (ja) 1993-11-22
LV10256A (lv) 1994-10-20
EP0535420A1 (de) 1993-04-07
NO923798L (no) 1993-04-05
SK301992A3 (en) 1995-10-11
TW223073B (ref) 1994-05-01
NO923798D0 (no) 1992-09-30
IL103329A0 (en) 1993-03-15
CN1071426A (zh) 1993-04-28
FI924353L (fi) 1993-04-05
FI924353A0 (fi) 1992-09-29
HRP920817A2 (en) 1996-08-31
NZ244320A (en) 1995-01-27
HU9203149D0 (en) 1992-12-28
AT398202B (de) 1994-10-25
ATA198791A (de) 1994-02-15

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