MXPA03001072A - El uso de bencilidenaminoguanidinas e hidroxiguanidinas como ligandos de receptor de melanocortina. - Google Patents
El uso de bencilidenaminoguanidinas e hidroxiguanidinas como ligandos de receptor de melanocortina.Info
- Publication number
- MXPA03001072A MXPA03001072A MXPA03001072A MXPA03001072A MXPA03001072A MX PA03001072 A MXPA03001072 A MX PA03001072A MX PA03001072 A MXPA03001072 A MX PA03001072A MX PA03001072 A MXPA03001072 A MX PA03001072A MX PA03001072 A MXPA03001072 A MX PA03001072A
- Authority
- MX
- Mexico
- Prior art keywords
- benzylideneaminoguanidines
- hydroxyguanidines
- receptor ligands
- melanocortin receptor
- carbon atoms
- Prior art date
Links
- 102000004378 Melanocortin Receptors Human genes 0.000 title abstract 2
- 108090000950 Melanocortin Receptors Proteins 0.000 title abstract 2
- 239000003446 ligand Substances 0.000 title abstract 2
- WNPXUCYRKHVMAD-UHFFFAOYSA-N 2-(benzylideneamino)guanidine Chemical class NC(N)=NN=CC1=CC=CC=C1 WNPXUCYRKHVMAD-UHFFFAOYSA-N 0.000 title 1
- WFBHRSAKANVBKH-UHFFFAOYSA-N N-hydroxyguanidine Chemical class NC(=N)NO WFBHRSAKANVBKH-UHFFFAOYSA-N 0.000 title 1
- -1 benzoyloxy, nitroxy, phenyl Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 108010008364 Melanocortins Proteins 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000002865 melanocortin Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000004950 trifluoroalkyl group Chemical group 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
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- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- C07C309/01—Sulfonic acids
- C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/45—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
- C07C309/46—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton having the sulfo groups bound to carbon atoms of non-condensed six-membered aromatic rings
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- C07C53/08—Acetic acid
- C07C53/10—Salts thereof
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- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
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- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0019357A GB0019357D0 (en) | 2000-08-07 | 2000-08-07 | Novel phenyl guanidines |
| PCT/GB2001/003534 WO2002011715A2 (en) | 2000-08-07 | 2001-08-07 | The use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA03001072A true MXPA03001072A (es) | 2004-03-10 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA03001072A MXPA03001072A (es) | 2000-08-07 | 2001-08-07 | El uso de bencilidenaminoguanidinas e hidroxiguanidinas como ligandos de receptor de melanocortina. |
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| EP (1) | EP1313461A2 (enExample) |
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| CA (1) | CA2417098A1 (enExample) |
| GB (1) | GB0019357D0 (enExample) |
| IL (2) | IL154272A0 (enExample) |
| MX (1) | MXPA03001072A (enExample) |
| WO (1) | WO2002011715A2 (enExample) |
| ZA (1) | ZA200300829B (enExample) |
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| GB0119172D0 (en) | 2001-08-06 | 2001-09-26 | Melacure Therapeutics Ab | Phenyl pyrrole derivatives |
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| WO2010075069A1 (en) | 2008-12-16 | 2010-07-01 | Schering Corporation | Bicyclic pyranone derivatives as nicotinic acid receptor agonists |
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| GB201300435D0 (en) * | 2013-01-10 | 2013-02-27 | Medical Res Council | Benzylideneguanidine Derivatives and Therapeutic Use for the Treatment of Protein Misfolding Diseases |
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-
2000
- 2000-08-07 GB GB0019357A patent/GB0019357D0/en not_active Ceased
-
2001
- 2001-08-07 MX MXPA03001072A patent/MXPA03001072A/es active IP Right Grant
- 2001-08-07 AU AU2001276522A patent/AU2001276522A1/en not_active Abandoned
- 2001-08-07 EP EP20010954176 patent/EP1313461A2/en not_active Withdrawn
- 2001-08-07 CA CA 2417098 patent/CA2417098A1/en not_active Abandoned
- 2001-08-07 US US10/343,325 patent/US20040024060A1/en not_active Abandoned
- 2001-08-07 BR BR0113053A patent/BR0113053A/pt not_active Application Discontinuation
- 2001-08-07 JP JP2002517052A patent/JP5654190B2/ja not_active Expired - Fee Related
- 2001-08-07 KR KR20037001846A patent/KR100929363B1/ko not_active Expired - Fee Related
- 2001-08-07 IL IL15427201A patent/IL154272A0/xx unknown
- 2001-08-07 WO PCT/GB2001/003534 patent/WO2002011715A2/en not_active Ceased
-
2003
- 2003-01-30 ZA ZA200300829A patent/ZA200300829B/xx unknown
- 2003-02-03 IL IL15427203A patent/IL154272A/en not_active IP Right Cessation
-
2006
- 2006-12-15 US US11/639,190 patent/US8148429B2/en not_active Expired - Fee Related
-
2007
- 2007-05-16 US US11/798,669 patent/US20070231267A1/en not_active Abandoned
-
2010
- 2010-09-28 US US12/892,402 patent/US8309609B2/en not_active Expired - Fee Related
-
2011
- 2011-07-04 JP JP2011148414A patent/JP5683396B2/ja not_active Expired - Fee Related
-
2012
- 2012-03-21 US US13/426,096 patent/US8410174B2/en not_active Expired - Fee Related
-
2013
- 2013-03-14 US US13/803,555 patent/US9227927B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20070088085A1 (en) | 2007-04-19 |
| JP2011246471A (ja) | 2011-12-08 |
| EP1313461A2 (en) | 2003-05-28 |
| ZA200300829B (en) | 2004-02-25 |
| GB0019357D0 (en) | 2000-09-27 |
| JP5654190B2 (ja) | 2015-01-14 |
| IL154272A (en) | 2010-12-30 |
| CA2417098A1 (en) | 2002-02-14 |
| US9227927B2 (en) | 2016-01-05 |
| WO2002011715A3 (en) | 2003-01-16 |
| IL154272A0 (en) | 2003-09-17 |
| JP2004505912A (ja) | 2004-02-26 |
| WO2002011715A2 (en) | 2002-02-14 |
| US8309609B2 (en) | 2012-11-13 |
| US8410174B2 (en) | 2013-04-02 |
| KR20030022371A (ko) | 2003-03-15 |
| US20040024060A1 (en) | 2004-02-05 |
| BR0113053A (pt) | 2003-07-08 |
| JP5683396B2 (ja) | 2015-03-11 |
| US20110015437A1 (en) | 2011-01-20 |
| US20130295009A1 (en) | 2013-11-07 |
| US8148429B2 (en) | 2012-04-03 |
| US20120178820A1 (en) | 2012-07-12 |
| KR100929363B1 (ko) | 2009-12-02 |
| US20070231267A1 (en) | 2007-10-04 |
| AU2001276522A1 (en) | 2002-02-18 |
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