GB923398A - Diphenyl mono-and bis-formyl guanylhydrazones - Google Patents

Diphenyl mono-and bis-formyl guanylhydrazones

Info

Publication number
GB923398A
GB923398A GB2884561A GB2884561A GB923398A GB 923398 A GB923398 A GB 923398A GB 2884561 A GB2884561 A GB 2884561A GB 2884561 A GB2884561 A GB 2884561A GB 923398 A GB923398 A GB 923398A
Authority
GB
United Kingdom
Prior art keywords
diphenylsulphide
reacting
guanylhydrazones
formyl
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2884561A
Inventor
Guido Cavallini
Elena Massarani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Francesco Vismara SpA
Original Assignee
Francesco Vismara SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Francesco Vismara SpA filed Critical Francesco Vismara SpA
Publication of GB923398A publication Critical patent/GB923398A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)

Abstract

The invention comprises mono- and bisformyl guanylhydrazones of the formula <FORM:0923398/IV(a)/1> where R represents the group C6H5CH2-; C6H5CH2CH2-; C6H5-CH=CH-; ZC6H4 CH2; ZC6H4CH2CH2-; ZC6H4CH=CH-; ZC6H4S-; where Z represents a -CH= NNH-C(:NH)NH2 group, together with their acid addition salts and the preparation thereof by reacting an aminoguanidine with a monoer di-aldehyde of the general formula <FORM:0923398/IV(a)/2> (in which R1 represents the group C6H5CH2-; C6H5CH2CH2; C6H5CH=CH-; OHC6H4 CH2-; OCHC6H4CH2CH2-; OHCC6H4CH2 =CH-; OHCC6H4CH=CH-; or OHCC6 H4S-) or a functional derivative thereof. 4,41-Diphenylsulphide-dialdehyde is prepared by reacting diphenylsulphide with formaldehyde in the presence of aluminium chloride and hydrochloric acid to give 4,4-bischloromethyl-diphenylsulphide and reacting this with hexamethylenetetramine. 4,41-Stilbene-dialdehyde is prepared by treating diazotised p-aminobenzaldehyde with p-formyl-cinnamic acid.
GB2884561A 1960-08-09 1961-08-09 Diphenyl mono-and bis-formyl guanylhydrazones Expired GB923398A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1426560 1960-08-09

Publications (1)

Publication Number Publication Date
GB923398A true GB923398A (en) 1963-04-10

Family

ID=11144942

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2884561A Expired GB923398A (en) 1960-08-09 1961-08-09 Diphenyl mono-and bis-formyl guanylhydrazones

Country Status (1)

Country Link
GB (1) GB923398A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0746312A1 (en) * 1994-01-21 1996-12-11 The Picower Institute For Medical Research Guanylhydrazones for treating inflammatory conditions
WO2002000613A2 (en) * 2000-06-27 2002-01-03 Axxima Pharmaceuticals Ag Inhibitors of hepatitis b virus infection
WO2005039494A2 (en) * 2003-10-21 2005-05-06 Message Pharmaceuticals, Inc. Inhibitors of rnase p proteins as antibacterial compounds
US8148429B2 (en) 2000-08-07 2012-04-03 Anamar Ab Use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands
US8372878B2 (en) 2006-12-14 2013-02-12 Anamar Ab Aminoguanidines as melanocortin receptor ligands

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0746312A1 (en) * 1994-01-21 1996-12-11 The Picower Institute For Medical Research Guanylhydrazones for treating inflammatory conditions
EP0746312A4 (en) * 1994-01-21 1999-05-26 Picower Inst Med Res Guanylhydrazones for treating inflammatory conditions
EP1160240A1 (en) * 1994-01-21 2001-12-05 The Picower Institute For Medical Research Guanylhydrazones for treating inflammatory conditions
WO2002000613A2 (en) * 2000-06-27 2002-01-03 Axxima Pharmaceuticals Ag Inhibitors of hepatitis b virus infection
WO2002000613A3 (en) * 2000-06-27 2002-11-07 Axxima Pharmaceuticals Ag Inhibitors of hepatitis b virus infection
US8148429B2 (en) 2000-08-07 2012-04-03 Anamar Ab Use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands
US8309609B2 (en) 2000-08-07 2012-11-13 Anamar Ab Use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands
US8410174B2 (en) 2000-08-07 2013-04-02 Anamar Ab Method for treating arthritis
US9227927B2 (en) 2000-08-07 2016-01-05 Anamar Ab Method of treating inflammation
WO2005039494A2 (en) * 2003-10-21 2005-05-06 Message Pharmaceuticals, Inc. Inhibitors of rnase p proteins as antibacterial compounds
WO2005039494A3 (en) * 2003-10-21 2005-07-21 Message Pharmaceuticals Inc Inhibitors of rnase p proteins as antibacterial compounds
US8372878B2 (en) 2006-12-14 2013-02-12 Anamar Ab Aminoguanidines as melanocortin receptor ligands

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