GB923398A - Diphenyl mono-and bis-formyl guanylhydrazones - Google Patents
Diphenyl mono-and bis-formyl guanylhydrazonesInfo
- Publication number
- GB923398A GB923398A GB2884561A GB2884561A GB923398A GB 923398 A GB923398 A GB 923398A GB 2884561 A GB2884561 A GB 2884561A GB 2884561 A GB2884561 A GB 2884561A GB 923398 A GB923398 A GB 923398A
- Authority
- GB
- United Kingdom
- Prior art keywords
- diphenylsulphide
- reacting
- guanylhydrazones
- formyl
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
- C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
Abstract
The invention comprises mono- and bisformyl guanylhydrazones of the formula <FORM:0923398/IV(a)/1> where R represents the group C6H5CH2-; C6H5CH2CH2-; C6H5-CH=CH-; ZC6H4 CH2; ZC6H4CH2CH2-; ZC6H4CH=CH-; ZC6H4S-; where Z represents a -CH= NNH-C(:NH)NH2 group, together with their acid addition salts and the preparation thereof by reacting an aminoguanidine with a monoer di-aldehyde of the general formula <FORM:0923398/IV(a)/2> (in which R1 represents the group C6H5CH2-; C6H5CH2CH2; C6H5CH=CH-; OHC6H4 CH2-; OCHC6H4CH2CH2-; OHCC6H4CH2 =CH-; OHCC6H4CH=CH-; or OHCC6 H4S-) or a functional derivative thereof. 4,41-Diphenylsulphide-dialdehyde is prepared by reacting diphenylsulphide with formaldehyde in the presence of aluminium chloride and hydrochloric acid to give 4,4-bischloromethyl-diphenylsulphide and reacting this with hexamethylenetetramine. 4,41-Stilbene-dialdehyde is prepared by treating diazotised p-aminobenzaldehyde with p-formyl-cinnamic acid.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1426560 | 1960-08-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB923398A true GB923398A (en) | 1963-04-10 |
Family
ID=11144942
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2884561A Expired GB923398A (en) | 1960-08-09 | 1961-08-09 | Diphenyl mono-and bis-formyl guanylhydrazones |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB923398A (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0746312A1 (en) * | 1994-01-21 | 1996-12-11 | The Picower Institute For Medical Research | Guanylhydrazones for treating inflammatory conditions |
WO2002000613A2 (en) * | 2000-06-27 | 2002-01-03 | Axxima Pharmaceuticals Ag | Inhibitors of hepatitis b virus infection |
WO2005039494A2 (en) * | 2003-10-21 | 2005-05-06 | Message Pharmaceuticals, Inc. | Inhibitors of rnase p proteins as antibacterial compounds |
US8148429B2 (en) | 2000-08-07 | 2012-04-03 | Anamar Ab | Use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands |
US8372878B2 (en) | 2006-12-14 | 2013-02-12 | Anamar Ab | Aminoguanidines as melanocortin receptor ligands |
-
1961
- 1961-08-09 GB GB2884561A patent/GB923398A/en not_active Expired
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0746312A1 (en) * | 1994-01-21 | 1996-12-11 | The Picower Institute For Medical Research | Guanylhydrazones for treating inflammatory conditions |
EP0746312A4 (en) * | 1994-01-21 | 1999-05-26 | Picower Inst Med Res | Guanylhydrazones for treating inflammatory conditions |
EP1160240A1 (en) * | 1994-01-21 | 2001-12-05 | The Picower Institute For Medical Research | Guanylhydrazones for treating inflammatory conditions |
WO2002000613A2 (en) * | 2000-06-27 | 2002-01-03 | Axxima Pharmaceuticals Ag | Inhibitors of hepatitis b virus infection |
WO2002000613A3 (en) * | 2000-06-27 | 2002-11-07 | Axxima Pharmaceuticals Ag | Inhibitors of hepatitis b virus infection |
US8148429B2 (en) | 2000-08-07 | 2012-04-03 | Anamar Ab | Use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands |
US8309609B2 (en) | 2000-08-07 | 2012-11-13 | Anamar Ab | Use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands |
US8410174B2 (en) | 2000-08-07 | 2013-04-02 | Anamar Ab | Method for treating arthritis |
US9227927B2 (en) | 2000-08-07 | 2016-01-05 | Anamar Ab | Method of treating inflammation |
WO2005039494A2 (en) * | 2003-10-21 | 2005-05-06 | Message Pharmaceuticals, Inc. | Inhibitors of rnase p proteins as antibacterial compounds |
WO2005039494A3 (en) * | 2003-10-21 | 2005-07-21 | Message Pharmaceuticals Inc | Inhibitors of rnase p proteins as antibacterial compounds |
US8372878B2 (en) | 2006-12-14 | 2013-02-12 | Anamar Ab | Aminoguanidines as melanocortin receptor ligands |
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