MXPA02008789A - Compuestos de 1-(-(hetero)aril-1-perhidroxialquilmetil)-piperazina, procedimientos para su preparacion y medicamentos que contienen estos compuestos. - Google Patents
Compuestos de 1-(-(hetero)aril-1-perhidroxialquilmetil)-piperazina, procedimientos para su preparacion y medicamentos que contienen estos compuestos.Info
- Publication number
- MXPA02008789A MXPA02008789A MXPA02008789A MXPA02008789A MXPA02008789A MX PA02008789 A MXPA02008789 A MX PA02008789A MX PA02008789 A MXPA02008789 A MX PA02008789A MX PA02008789 A MXPA02008789 A MX PA02008789A MX PA02008789 A MXPA02008789 A MX PA02008789A
- Authority
- MX
- Mexico
- Prior art keywords
- compounds
- butyl
- dichlorophenyl
- piperazinyl
- optionally substituted
- Prior art date
Links
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- 238000000034 method Methods 0.000 claims abstract description 14
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- 125000000217 alkyl group Chemical group 0.000 claims description 26
- -1 {4 - [(2S) -2,3-dihydroxy-1- (2-furyl) propyl] -1-piperazinyl} -butyl Chemical group 0.000 claims description 25
- 239000002253 acid Substances 0.000 claims description 22
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Indole Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10145044A DE10145044A1 (de) | 2001-09-13 | 2001-09-13 | Neue 1-[1-(Hetero)aryl-1-perhydroxyalkylmethyl]-Piperazinverbindungen, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA02008789A true MXPA02008789A (es) | 2003-03-18 |
Family
ID=7698848
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA02008789A MXPA02008789A (es) | 2001-09-13 | 2002-09-09 | Compuestos de 1-(-(hetero)aril-1-perhidroxialquilmetil)-piperazina, procedimientos para su preparacion y medicamentos que contienen estos compuestos. |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6770649B2 (en:Method) |
| EP (1) | EP1293506B1 (en:Method) |
| JP (1) | JP4353684B2 (en:Method) |
| KR (1) | KR100909746B1 (en:Method) |
| CN (1) | CN1232513C (en:Method) |
| AR (1) | AR036487A1 (en:Method) |
| AT (1) | ATE305464T1 (en:Method) |
| AU (1) | AU2002301141B2 (en:Method) |
| BR (1) | BR0203716A (en:Method) |
| CA (1) | CA2403139C (en:Method) |
| DE (2) | DE10145044A1 (en:Method) |
| DK (1) | DK1293506T3 (en:Method) |
| DZ (1) | DZ3292A1 (en:Method) |
| ES (1) | ES2250561T3 (en:Method) |
| HU (1) | HU227612B1 (en:Method) |
| IL (1) | IL151497A (en:Method) |
| MX (1) | MXPA02008789A (en:Method) |
| NO (1) | NO324867B1 (en:Method) |
| NZ (1) | NZ521154A (en:Method) |
| PL (1) | PL356018A1 (en:Method) |
| PT (1) | PT1293506E (en:Method) |
| RU (1) | RU2301807C2 (en:Method) |
| SI (1) | SI1293506T1 (en:Method) |
| TW (1) | TWI254046B (en:Method) |
| UA (1) | UA75590C2 (en:Method) |
| ZA (1) | ZA200206731B (en:Method) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2603030C (en) | 2005-03-31 | 2013-11-19 | Nippon Zoki Pharmaceutical Co., Ltd. | Benzyloxypropylamine derivative |
| RU2419609C2 (ru) * | 2005-11-30 | 2011-05-27 | Зольвай Фармасьютиклз Гмбх | Новые антагонисты nk1 и nk2 |
| US7592344B2 (en) | 2005-11-30 | 2009-09-22 | Solvay Pharmaceuticals Gmbh | NK1 and NK2-antagonists and compositions and methods of using the same |
| CN103387549A (zh) * | 2012-05-10 | 2013-11-13 | 广州医学院 | 三个苯并三氮唑类芳基哌嗪化合物的消旋体和光学异构体及其制备方法和用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1575904A (en) * | 1976-04-23 | 1980-10-01 | Lilly Industries Ltd | Phenyl piperazines |
| IE903957A1 (en) * | 1989-11-06 | 1991-05-08 | Sanofi Sa | Aromatic amine compounds, their method of preparation and¹pharmaceutical compositions in which they are present |
| IL99320A (en) * | 1990-09-05 | 1995-07-31 | Sanofi Sa | Arylalkylamines, their preparation and pharmaceutical compositions containing them |
| DE69534213T2 (de) * | 1994-10-25 | 2006-01-12 | Astrazeneca Ab | Therapeutisch wirksame Heterocyclen |
| JP2003530381A (ja) * | 2000-04-06 | 2003-10-14 | アストラゼネカ・アクチエボラーグ | 化合物 |
-
2000
- 2000-09-14 DZ DZ020227A patent/DZ3292A1/fr active
-
2001
- 2001-09-13 DE DE10145044A patent/DE10145044A1/de not_active Withdrawn
-
2002
- 2002-08-15 TW TW091118380A patent/TWI254046B/zh not_active IP Right Cessation
- 2002-08-22 ZA ZA200206731A patent/ZA200206731B/xx unknown
- 2002-08-22 AR ARP020103153A patent/AR036487A1/es active IP Right Grant
- 2002-08-27 IL IL151497A patent/IL151497A/en not_active IP Right Cessation
- 2002-09-03 NZ NZ521154A patent/NZ521154A/en not_active IP Right Cessation
- 2002-09-06 KR KR1020020053771A patent/KR100909746B1/ko not_active Expired - Fee Related
- 2002-09-07 ES ES02020115T patent/ES2250561T3/es not_active Expired - Lifetime
- 2002-09-07 EP EP02020115A patent/EP1293506B1/de not_active Expired - Lifetime
- 2002-09-07 AT AT02020115T patent/ATE305464T1/de active
- 2002-09-07 DE DE50204379T patent/DE50204379D1/de not_active Expired - Lifetime
- 2002-09-07 SI SI200230195T patent/SI1293506T1/sl unknown
- 2002-09-07 DK DK02020115T patent/DK1293506T3/da active
- 2002-09-07 PT PT02020115T patent/PT1293506E/pt unknown
- 2002-09-09 MX MXPA02008789A patent/MXPA02008789A/es active IP Right Grant
- 2002-09-09 HU HU0202967A patent/HU227612B1/hu not_active IP Right Cessation
- 2002-09-11 CN CNB021315566A patent/CN1232513C/zh not_active Expired - Fee Related
- 2002-09-11 UA UA2002097386A patent/UA75590C2/uk unknown
- 2002-09-11 JP JP2002265969A patent/JP4353684B2/ja not_active Expired - Fee Related
- 2002-09-12 AU AU2002301141A patent/AU2002301141B2/en not_active Ceased
- 2002-09-12 BR BR0203716-5A patent/BR0203716A/pt not_active IP Right Cessation
- 2002-09-12 RU RU2002124199/04A patent/RU2301807C2/ru not_active IP Right Cessation
- 2002-09-12 PL PL02356018A patent/PL356018A1/xx not_active Application Discontinuation
- 2002-09-12 NO NO20024351A patent/NO324867B1/no not_active IP Right Cessation
- 2002-09-13 US US10/242,678 patent/US6770649B2/en not_active Expired - Lifetime
- 2002-09-13 CA CA2403139A patent/CA2403139C/en not_active Expired - Fee Related
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