SI1293506T1 - Nove 1-(1-(hetero)aril-1-perhidroksialkilmetil)-piperazinove spojine, postopek za njihovo izdelavo in zdravila, ki te spojine vsebujejo - Google Patents
Nove 1-(1-(hetero)aril-1-perhidroksialkilmetil)-piperazinove spojine, postopek za njihovo izdelavo in zdravila, ki te spojine vsebujejoInfo
- Publication number
- SI1293506T1 SI1293506T1 SI200230195T SI200230195T SI1293506T1 SI 1293506 T1 SI1293506 T1 SI 1293506T1 SI 200230195 T SI200230195 T SI 200230195T SI 200230195 T SI200230195 T SI 200230195T SI 1293506 T1 SI1293506 T1 SI 1293506T1
- Authority
- SI
- Slovenia
- Prior art keywords
- perhydroxyalkylmethyl
- hetero
- aryl
- preparation
- new
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10145044A DE10145044A1 (de) | 2001-09-13 | 2001-09-13 | Neue 1-[1-(Hetero)aryl-1-perhydroxyalkylmethyl]-Piperazinverbindungen, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| EP02020115A EP1293506B1 (de) | 2001-09-13 | 2002-09-07 | Neue 1-(1-(Hetero)aryl-1-perhydroxyalkylmethyl)-Piperazinverbindungen, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1293506T1 true SI1293506T1 (sl) | 2005-12-31 |
Family
ID=7698848
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200230195T SI1293506T1 (sl) | 2001-09-13 | 2002-09-07 | Nove 1-(1-(hetero)aril-1-perhidroksialkilmetil)-piperazinove spojine, postopek za njihovo izdelavo in zdravila, ki te spojine vsebujejo |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US6770649B2 (sl) |
| EP (1) | EP1293506B1 (sl) |
| JP (1) | JP4353684B2 (sl) |
| KR (1) | KR100909746B1 (sl) |
| CN (1) | CN1232513C (sl) |
| AR (1) | AR036487A1 (sl) |
| AT (1) | ATE305464T1 (sl) |
| AU (1) | AU2002301141B2 (sl) |
| BR (1) | BR0203716A (sl) |
| CA (1) | CA2403139C (sl) |
| DE (2) | DE10145044A1 (sl) |
| DK (1) | DK1293506T3 (sl) |
| DZ (1) | DZ3292A1 (sl) |
| ES (1) | ES2250561T3 (sl) |
| HK (1) | HK1053648A1 (sl) |
| HU (1) | HU227612B1 (sl) |
| IL (1) | IL151497A (sl) |
| MX (1) | MXPA02008789A (sl) |
| NO (1) | NO324867B1 (sl) |
| NZ (1) | NZ521154A (sl) |
| PL (1) | PL356018A1 (sl) |
| PT (1) | PT1293506E (sl) |
| RU (1) | RU2301807C2 (sl) |
| SI (1) | SI1293506T1 (sl) |
| TW (1) | TWI254046B (sl) |
| UA (1) | UA75590C2 (sl) |
| ZA (1) | ZA200206731B (sl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2396557T3 (es) | 2005-03-31 | 2013-02-22 | Nippon Zoki Pharmaceutical Co. Ltd. | Derivado de benciloxipropilamina |
| US7592344B2 (en) | 2005-11-30 | 2009-09-22 | Solvay Pharmaceuticals Gmbh | NK1 and NK2-antagonists and compositions and methods of using the same |
| ATE550324T1 (de) * | 2005-11-30 | 2012-04-15 | Abbott Products Gmbh | Neue nk1- und nk2-antagonisten |
| CN103387549A (zh) * | 2012-05-10 | 2013-11-13 | 广州医学院 | 三个苯并三氮唑类芳基哌嗪化合物的消旋体和光学异构体及其制备方法和用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE903957A1 (en) * | 1989-11-06 | 1991-05-08 | Sanofi Sa | Aromatic amine compounds, their method of preparation and¹pharmaceutical compositions in which they are present |
| IL99320A (en) * | 1990-09-05 | 1995-07-31 | Sanofi Sa | Arylalkylamines, their preparation and pharmaceutical preparations containing them |
| DE69534213T2 (de) * | 1994-10-25 | 2006-01-12 | Astrazeneca Ab | Therapeutisch wirksame Heterocyclen |
| ATE308513T1 (de) * | 2000-04-06 | 2005-11-15 | Naphthamid-neurokinin antagonisten zur verwendung als medikamente |
-
2000
- 2000-09-14 DZ DZ020227A patent/DZ3292A1/fr active
-
2001
- 2001-09-13 DE DE10145044A patent/DE10145044A1/de not_active Withdrawn
-
2002
- 2002-08-15 TW TW091118380A patent/TWI254046B/zh not_active IP Right Cessation
- 2002-08-22 ZA ZA200206731A patent/ZA200206731B/xx unknown
- 2002-08-22 AR ARP020103153A patent/AR036487A1/es active IP Right Grant
- 2002-08-27 IL IL151497A patent/IL151497A/en not_active IP Right Cessation
- 2002-09-03 NZ NZ521154A patent/NZ521154A/en not_active IP Right Cessation
- 2002-09-06 KR KR1020020053771A patent/KR100909746B1/ko not_active IP Right Cessation
- 2002-09-07 EP EP02020115A patent/EP1293506B1/de not_active Expired - Lifetime
- 2002-09-07 SI SI200230195T patent/SI1293506T1/sl unknown
- 2002-09-07 ES ES02020115T patent/ES2250561T3/es not_active Expired - Lifetime
- 2002-09-07 PT PT02020115T patent/PT1293506E/pt unknown
- 2002-09-07 DK DK02020115T patent/DK1293506T3/da active
- 2002-09-07 DE DE50204379T patent/DE50204379D1/de not_active Expired - Lifetime
- 2002-09-07 AT AT02020115T patent/ATE305464T1/de active
- 2002-09-09 MX MXPA02008789A patent/MXPA02008789A/es active IP Right Grant
- 2002-09-09 HU HU0202967A patent/HU227612B1/hu not_active IP Right Cessation
- 2002-09-11 CN CNB021315566A patent/CN1232513C/zh not_active Expired - Fee Related
- 2002-09-11 JP JP2002265969A patent/JP4353684B2/ja not_active Expired - Fee Related
- 2002-09-11 UA UA2002097386A patent/UA75590C2/uk unknown
- 2002-09-12 RU RU2002124199/04A patent/RU2301807C2/ru not_active IP Right Cessation
- 2002-09-12 NO NO20024351A patent/NO324867B1/no not_active IP Right Cessation
- 2002-09-12 PL PL02356018A patent/PL356018A1/xx not_active Application Discontinuation
- 2002-09-12 BR BR0203716-5A patent/BR0203716A/pt not_active IP Right Cessation
- 2002-09-12 AU AU2002301141A patent/AU2002301141B2/en not_active Ceased
- 2002-09-13 CA CA2403139A patent/CA2403139C/en not_active Expired - Fee Related
- 2002-09-13 US US10/242,678 patent/US6770649B2/en not_active Expired - Lifetime
-
2003
- 2003-08-08 HK HK03105680A patent/HK1053648A1/xx not_active IP Right Cessation
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