MXPA02000404A - Formulaciones de hormona de crecimiento. - Google Patents
Formulaciones de hormona de crecimiento.Info
- Publication number
- MXPA02000404A MXPA02000404A MXPA02000404A MXPA02000404A MXPA02000404A MX PA02000404 A MXPA02000404 A MX PA02000404A MX PA02000404 A MXPA02000404 A MX PA02000404A MX PA02000404 A MXPA02000404 A MX PA02000404A MX PA02000404 A MXPA02000404 A MX PA02000404A
- Authority
- MX
- Mexico
- Prior art keywords
- growth hormone
- temperatures
- formulation
- formulations
- hormone formulations
- Prior art date
Links
- 239000000122 growth hormone Substances 0.000 title abstract 5
- 102000018997 Growth Hormone Human genes 0.000 title abstract 4
- 108010051696 Growth Hormone Proteins 0.000 title abstract 4
- 238000009472 formulation Methods 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 4
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 1
- 229930195725 Mannitol Natural products 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 238000004220 aggregation Methods 0.000 abstract 1
- 230000002776 aggregation Effects 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 238000011109 contamination Methods 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 235000010355 mannitol Nutrition 0.000 abstract 1
- 239000000594 mannitol Substances 0.000 abstract 1
- 239000002736 nonionic surfactant Substances 0.000 abstract 1
- 239000008363 phosphate buffer Substances 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 238000005057 refrigeration Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9916252.1A GB9916252D0 (en) | 1999-07-12 | 1999-07-12 | Growth hormone formulation |
| GBGB9918902.9A GB9918902D0 (en) | 1999-08-12 | 1999-08-12 | Growth hormone formulation |
| PCT/GB2000/002664 WO2001003741A1 (en) | 1999-07-12 | 2000-07-11 | Growth hormone formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA02000404A true MXPA02000404A (es) | 2004-05-21 |
Family
ID=26315757
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA02000404A MXPA02000404A (es) | 1999-07-12 | 2000-07-11 | Formulaciones de hormona de crecimiento. |
Country Status (25)
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030162711A1 (en) * | 1996-04-24 | 2003-08-28 | Soren Bjorn | Pharmaceutical formulation |
| US20070179096A1 (en) * | 1996-04-24 | 2007-08-02 | Novo Nordisk A/S | Pharmaceutical Formulation |
| GB2371227A (en) * | 2001-01-10 | 2002-07-24 | Grandis Biotech Gmbh | Crystallisation - resistant aqueous growth hormone formulations |
| US20060165733A1 (en) * | 2002-07-09 | 2006-07-27 | Michael Betz | Liquid formulations with high concentration of hunan growth hormone (hgh) comprising phenol |
| US20060252682A1 (en) * | 2003-03-18 | 2006-11-09 | Ares Trading S.A. | Liquid growth hormone formulation and process of preparation thereof |
| US20090029911A1 (en) * | 2003-09-25 | 2009-01-29 | Ashley Martin Williams | Liquid Human Growth Hormone Formulation Containing Polyethylene Glycol |
| US8338374B2 (en) | 2003-12-23 | 2012-12-25 | Pharmacia Corporation | Stable growth hormone liquid formulation |
| MXPA06011029A (es) * | 2004-04-07 | 2007-01-25 | Ares Trading Sa | Formulacion liquida de hormona del crecimiento. |
| US8293532B2 (en) | 2009-03-26 | 2012-10-23 | Dow AgroSciences, L.L.C. | Method and apparatus for tissue transfer |
| IN2012DN02861A (cg-RX-API-DMAC7.html) * | 2009-11-17 | 2015-07-24 | Ipsen Pharma Sas | |
| BR112014001921B1 (pt) | 2011-07-25 | 2022-05-10 | Sandoz Ag | Formulação aquosa farmaceuticamente aceitável, método para aumentar a estabilidade de uma formulação aquosa farmaceuticamente aceitável e embalagem principal |
| JP2013231030A (ja) * | 2012-04-30 | 2013-11-14 | Sun Pharmaceutical Industries Ltd | リュープロリド注射剤 |
| JP6001401B2 (ja) * | 2012-09-28 | 2016-10-05 | ユニ・チャーム株式会社 | ウェットティッシュ用薬液及びウェットティッシュ |
| CN107735429B (zh) | 2015-12-10 | 2021-05-07 | 三菱瓦斯化学株式会社 | 光固化性组合物和光学材料 |
| JP6172880B1 (ja) * | 2017-02-01 | 2017-08-02 | 協和発酵キリン株式会社 | ダルベポエチンを含む液体医薬組成物 |
| EP3811962A4 (en) * | 2018-06-25 | 2022-03-16 | JCR Pharmaceuticals Co., Ltd. | Protein-containing aqueous liquid formulation |
| KR20230109655A (ko) * | 2020-11-16 | 2023-07-20 | 더블유.엘. 고어 앤드 어소시에이트스, 인코포레이티드 | 흐림점이 없는 사전 충전 다회 투여 주입 디바이스, 방법 및 제형 |
| CN112494638B (zh) * | 2020-12-22 | 2023-12-19 | 深圳科兴药业有限公司 | 一种人生长激素注射剂组合物及其制备方法 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4783441A (en) * | 1979-04-30 | 1988-11-08 | Hoechst Aktiengesellschaft | Aqueous protein solutions stable to denaturation |
| DE3325223A1 (de) * | 1983-07-13 | 1985-01-24 | Hoechst Ag, 6230 Frankfurt | Gegen denaturierung bestaendige, waessrige proteinloesungen, verfahren zu ihrer herstellung und ihre verwendung |
| IL79552A0 (en) * | 1985-07-30 | 1986-10-31 | Int Minerals & Chem Corp | Stabilization of growth promoting hormones |
| US4857505A (en) * | 1987-03-09 | 1989-08-15 | American Cyanamid Company | Sustained release compositions for parenteral administration and their use |
| IL86799A (en) * | 1987-07-02 | 1993-03-15 | Kabi Pharmacia Ab | Method and device for injection |
| US5151265A (en) * | 1987-11-03 | 1992-09-29 | Genentech, Inc. | Gamma interferon formulation |
| CA1331133C (en) * | 1988-03-01 | 1994-08-02 | Michael Jon Pikal | Pharmaceutical growth hormone formulations |
| US5763394A (en) * | 1988-04-15 | 1998-06-09 | Genentech, Inc. | Human growth hormone aqueous formulation |
| US5096885A (en) * | 1988-04-15 | 1992-03-17 | Genentech, Inc. | Human growth hormone formulation |
| JPH0383931A (ja) * | 1989-08-29 | 1991-04-09 | Sumitomo Pharmaceut Co Ltd | 低刺激性grf経鼻投与製剤 |
| US5126324A (en) * | 1990-06-07 | 1992-06-30 | Genentech, Inc. | Method of enhancing growth in patients using combination therapy |
| US5681814A (en) * | 1990-06-07 | 1997-10-28 | Genentech, Inc. | Formulated IGF-I Composition |
| DE69110290T2 (de) * | 1990-09-21 | 1995-10-19 | Novonordisk As | Adaptor. |
| SE9201073D0 (sv) * | 1992-04-03 | 1992-04-03 | Kabi Pharmacia Ab | Protein formulation |
| DE69334134T2 (de) * | 1992-07-31 | 2007-12-20 | Genentech, Inc., South San Francisco | Wässrige Formulierung enthaltend Menschliches Wachstumshormon |
| US5334162A (en) * | 1993-03-15 | 1994-08-02 | Eli Lilly And Company | Cartridge assembly for a lyophilized compound forming a disposable portion of an injector pen and method for same |
| US5496801A (en) * | 1993-12-23 | 1996-03-05 | Allelix Biopharmaceuticals Inc. | Parathyroid hormone formulation |
| US5610134A (en) * | 1994-04-15 | 1997-03-11 | Genentech, Inc. | Treatment of congestive heart failure |
| JPH0892125A (ja) * | 1994-09-21 | 1996-04-09 | Nippon Chem Res Kk | 水性医薬組成物 |
| SE9502927D0 (sv) * | 1995-08-24 | 1995-08-24 | Pharmacia Ab | Solution containing IGF-I |
| AUPN801296A0 (en) * | 1996-02-12 | 1996-03-07 | Csl Limited | Stabilised growth hormone formulation and method of preparation thereof |
| ES2169351T3 (es) * | 1996-02-13 | 2002-07-01 | Searle & Co | Combinaciones que tienen efectos inmunosupresores, que contienen inhibidores de ciclooxigenasa-2 y 5-lipoxigenasa. |
| ZA9711731B (en) * | 1996-12-31 | 1998-07-01 | Monsanto Co | Aqueous glycerol formulations of somatotropin |
| IL122732A0 (en) * | 1997-01-15 | 1998-08-16 | Akzo Nobel Nv | Liquid gonadotropin-containing formulation its preparation and a device containing same |
| JP3723857B2 (ja) * | 1998-02-04 | 2005-12-07 | 日本ケミカルリサーチ株式会社 | ヒト成長ホルモン含有水性医薬組成物 |
-
2000
- 2000-07-11 NZ NZ516507A patent/NZ516507A/xx unknown
- 2000-07-11 DE DE60038118T patent/DE60038118T2/de not_active Expired - Lifetime
- 2000-07-11 SK SK25-2002A patent/SK252002A3/sk unknown
- 2000-07-11 SI SI200030992T patent/SI1194170T1/sl unknown
- 2000-07-11 AT AT00946088T patent/ATE386501T1/de active
- 2000-07-11 BR BR0013162-8A patent/BR0013162A/pt not_active IP Right Cessation
- 2000-07-11 PL PL00353238A patent/PL353238A1/xx not_active Application Discontinuation
- 2000-07-11 MX MXPA02000404A patent/MXPA02000404A/es active IP Right Grant
- 2000-07-11 HK HK02106653.3A patent/HK1046358A1/zh unknown
- 2000-07-11 AU AU59975/00A patent/AU775107C/en not_active Expired
- 2000-07-11 EP EP00946088A patent/EP1194170B1/en not_active Expired - Lifetime
- 2000-07-11 CZ CZ200260A patent/CZ200260A3/cs unknown
- 2000-07-11 ES ES00946088T patent/ES2300268T3/es not_active Expired - Lifetime
- 2000-07-11 WO PCT/GB2000/002664 patent/WO2001003741A1/en not_active Ceased
- 2000-07-11 KR KR1020027000416A patent/KR20020031388A/ko not_active Ceased
- 2000-07-11 CN CN00810174A patent/CN1360506A/zh active Pending
- 2000-07-11 IL IL14725300A patent/IL147253A0/xx not_active IP Right Cessation
- 2000-07-11 JP JP2001509214A patent/JP2003504346A/ja active Pending
- 2000-07-11 TR TR2002/00034T patent/TR200200034T2/xx unknown
- 2000-07-11 HU HU0202189A patent/HUP0202189A3/hu unknown
- 2000-07-11 CA CA2378949A patent/CA2378949C/en not_active Expired - Lifetime
- 2000-07-13 AR ARP000103593A patent/AR024728A1/es unknown
- 2000-08-24 TW TW089117050A patent/TWI247608B/zh not_active IP Right Cessation
-
2001
- 2001-12-24 IL IL147253A patent/IL147253A/en unknown
-
2002
- 2002-01-11 NO NO20020151A patent/NO20020151L/no not_active Application Discontinuation
-
2005
- 2005-10-03 US US11/242,499 patent/US20060029635A1/en not_active Abandoned
-
2011
- 2011-09-26 JP JP2011208852A patent/JP2012051891A/ja active Pending
-
2014
- 2014-06-02 JP JP2014113773A patent/JP5941496B2/ja not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |