MX9700890A - 1, 4-benzotiazepina-1, 1-dioxidos hipolipidemicos. - Google Patents

1, 4-benzotiazepina-1, 1-dioxidos hipolipidemicos.

Info

Publication number
MX9700890A
MX9700890A MX9700890A MX9700890A MX9700890A MX 9700890 A MX9700890 A MX 9700890A MX 9700890 A MX9700890 A MX 9700890A MX 9700890 A MX9700890 A MX 9700890A MX 9700890 A MX9700890 A MX 9700890A
Authority
MX
Mexico
Prior art keywords
hypolipidemic
benzothiazepine
dioxides
novel
prophylaxis
Prior art date
Application number
MX9700890A
Other languages
English (en)
Inventor
Lawrence Edward Brieaddy
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of MX9700890A publication Critical patent/MX9700890A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La invencion se refiere a los compuestos hipolipidémicos nuevos de la formula (I), con los procesos y los intermediarios nuevos para su preparacion, las composiciones farmacéuticas que los contienen y con su uso en la medicina, en forma particular en la profilaxis y en el tratamiento de las condiciones hiperlipidémicas, tales como la aterosclerosis.
MX9700890A 1994-08-10 1995-08-09 1, 4-benzotiazepina-1, 1-dioxidos hipolipidemicos. MX9700890A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28852794A 1994-08-10 1994-08-10
PCT/GB1995/001884 WO1996005188A1 (en) 1994-08-10 1995-08-09 Hypolipidemic 1,4-benzothiazepine-1,1-dioxides

Publications (1)

Publication Number Publication Date
MX9700890A true MX9700890A (es) 1997-04-30

Family

ID=23107516

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9700890A MX9700890A (es) 1994-08-10 1995-08-09 1, 4-benzotiazepina-1, 1-dioxidos hipolipidemicos.

Country Status (31)

Country Link
US (1) US5910494A (es)
EP (2) EP0775126B1 (es)
JP (1) JP2935756B2 (es)
KR (1) KR100354288B1 (es)
CN (1) CN1059673C (es)
AP (1) AP720A (es)
AT (1) ATE226946T1 (es)
AU (1) AU696073B2 (es)
BG (1) BG62048B1 (es)
BR (1) BR9508586A (es)
CA (1) CA2197099A1 (es)
CZ (1) CZ37397A3 (es)
DE (1) DE69528704T2 (es)
DK (1) DK0775126T3 (es)
EE (1) EE9700028A (es)
ES (1) ES2185711T3 (es)
FI (1) FI970531A0 (es)
HK (1) HK1003936A1 (es)
HU (1) HUT77129A (es)
IL (1) IL114877A (es)
IS (1) IS4418A (es)
MX (1) MX9700890A (es)
NO (1) NO308131B1 (es)
NZ (1) NZ290911A (es)
OA (1) OA10597A (es)
PL (1) PL184512B1 (es)
PT (1) PT775126E (es)
RU (1) RU2156245C2 (es)
SK (1) SK17797A3 (es)
WO (1) WO1996005188A1 (es)
ZA (1) ZA956647B (es)

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US5276025A (en) * 1992-09-09 1994-01-04 Merck & Co., Inc. Heterobicyclic sulfonamides
IL108634A0 (en) * 1993-02-15 1994-05-30 Wellcome Found Hypolipidaemic heterocyclic compounds, their prepatation and pharmaceutical compositions containing them
ZA941003B (en) * 1993-02-15 1995-08-14 Wellcome Found Hypolipidaemic compounds
PT781278E (pt) * 1994-09-13 2001-08-30 Monsanto Co Novas benzotiepinas com actividade inibidora do transporte de acido biliar ileal e da remocao do taurocolato
GB9423172D0 (en) * 1994-11-17 1995-01-04 Wellcom Foundation The Limited Hypolipidemic benzothiazepines

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IL114877A (en) 1999-07-14
JPH10504035A (ja) 1998-04-14
IL114877A0 (en) 1995-12-08
BR9508586A (pt) 1998-07-14
CN1059673C (zh) 2000-12-20
AP720A (en) 1999-01-08
CA2197099A1 (en) 1996-02-22
NO970585D0 (no) 1997-02-07
PT775126E (pt) 2003-02-28
HUT77129A (hu) 1998-03-02
FI970531A (fi) 1997-02-07
US5910494A (en) 1999-06-08
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ES2185711T3 (es) 2003-05-01
BG62048B1 (bg) 1999-01-29
EP0775126B1 (en) 2002-10-30
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NO308131B1 (no) 2000-07-31
DE69528704D1 (de) 2002-12-05
KR100354288B1 (ko) 2003-01-06
AU4426096A (en) 1996-03-07
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CN1161035A (zh) 1997-10-01

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