MX9703546A - Benzotiazepinas hipolipidemicas. - Google Patents

Benzotiazepinas hipolipidemicas.

Info

Publication number
MX9703546A
MX9703546A MX9703546A MX9703546A MX9703546A MX 9703546 A MX9703546 A MX 9703546A MX 9703546 A MX9703546 A MX 9703546A MX 9703546 A MX9703546 A MX 9703546A MX 9703546 A MX9703546 A MX 9703546A
Authority
MX
Mexico
Prior art keywords
benzothiazepines
hypolipidemic
arteriosclerosis
prophylaxis
intermediates
Prior art date
Application number
MX9703546A
Other languages
English (en)
Other versions
MXPA97003546A (es
Inventor
Lawrence Edward Brieaddy
Anthony Louis Handlon
Gordon Lewis Hodgson Jr
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of MXPA97003546A publication Critical patent/MXPA97003546A/es
Publication of MX9703546A publication Critical patent/MX9703546A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)

Abstract

La invencion está relacionada con compuestos hipolipidémicos novedosos de la formula (I), con los procesos y los intermediarios originales para su preparacion, con composiciones farmacéuticamente conteniédoles y con su uso en medicina, particularmente en la profilaxis y tratamiento de condiciones hiperlipidémicas y enfermedades asociadas, tales como la arteriosclerosis.
MX9703546A 1994-11-17 1995-11-16 Benzotiazepinas hipolipidemicas. MX9703546A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9423172.7 1994-11-17
GB9423172A GB9423172D0 (en) 1994-11-17 1994-11-17 Hypolipidemic benzothiazepines
PCT/GB1995/002700 WO1996016051A1 (en) 1994-11-17 1995-11-16 Hypolipidemic benzothiazepines

Publications (2)

Publication Number Publication Date
MXPA97003546A MXPA97003546A (es) 1997-08-01
MX9703546A true MX9703546A (es) 1997-08-30

Family

ID=10764525

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9703546A MX9703546A (es) 1994-11-17 1995-11-16 Benzotiazepinas hipolipidemicas.

Country Status (22)

Country Link
US (1) US5998400A (es)
EP (1) EP0792268B1 (es)
JP (1) JP2868623B2 (es)
KR (1) KR970707111A (es)
CN (1) CN1059674C (es)
AT (1) ATE189891T1 (es)
AU (1) AU706325B2 (es)
BR (1) BR9509683A (es)
CZ (1) CZ147397A3 (es)
DE (1) DE69515183T2 (es)
DK (1) DK0792268T3 (es)
ES (1) ES2144151T3 (es)
FI (1) FI972085A7 (es)
GB (1) GB9423172D0 (es)
GR (1) GR3033450T3 (es)
HU (1) HUT77412A (es)
MX (1) MX9703546A (es)
NO (1) NO308470B1 (es)
NZ (1) NZ295426A (es)
PL (1) PL320093A1 (es)
PT (1) PT792268E (es)
WO (1) WO1996016051A1 (es)

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Also Published As

Publication number Publication date
GR3033450T3 (en) 2000-09-29
DK0792268T3 (da) 2000-07-31
FI972085L (fi) 1997-05-15
FI972085A0 (fi) 1997-05-15
ES2144151T3 (es) 2000-06-01
NZ295426A (en) 1997-10-24
US5998400A (en) 1999-12-07
BR9509683A (pt) 1997-09-16
JP2868623B2 (ja) 1999-03-10
EP0792268B1 (en) 2000-02-23
DE69515183D1 (de) 2000-03-30
JPH11500102A (ja) 1999-01-06
CN1164230A (zh) 1997-11-05
FI972085A7 (fi) 1997-05-15
NO972261D0 (no) 1997-05-16
NO972261L (no) 1997-07-16
WO1996016051A1 (en) 1996-05-30
PL320093A1 (en) 1997-09-15
DE69515183T2 (de) 2000-08-17
ATE189891T1 (de) 2000-03-15
CN1059674C (zh) 2000-12-20
EP0792268A1 (en) 1997-09-03
CZ147397A3 (en) 1997-11-12
NO308470B1 (no) 2000-09-18
KR970707111A (ko) 1997-12-01
PT792268E (pt) 2000-06-30
HUT77412A (hu) 1998-04-28
AU706325B2 (en) 1999-06-17
AU3876295A (en) 1996-06-17
GB9423172D0 (en) 1995-01-04

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