MX9606459A - MANIPULACION DE ACTIVIDAD DE ENZIMA OXIDASA DE PROTOPORFIRINOGENO EN ORGANISMOS EUCARIaTICOS. - Google Patents

MANIPULACION DE ACTIVIDAD DE ENZIMA OXIDASA DE PROTOPORFIRINOGENO EN ORGANISMOS EUCARIaTICOS.

Info

Publication number
MX9606459A
MX9606459A MX9606459A MX9606459A MX9606459A MX 9606459 A MX9606459 A MX 9606459A MX 9606459 A MX9606459 A MX 9606459A MX 9606459 A MX9606459 A MX 9606459A MX 9606459 A MX9606459 A MX 9606459A
Authority
MX
Mexico
Prior art keywords
protox
plants
native
protoporphyrinogen oxidase
eukaryotic
Prior art date
Application number
MX9606459A
Other languages
English (en)
Other versions
MX237061B (es
Inventor
Eric Russell Ward
Sandra Volrath
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX9606459A publication Critical patent/MX9606459A/es
Publication of MX237061B publication Critical patent/MX237061B/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
    • C12Y103/03—Oxidoreductases acting on the CH-CH group of donors (1.3) with oxygen as acceptor (1.3.3)
    • C12Y103/03004—Protoporphyrinogen oxidase (1.3.3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8274—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/04—Plant cells or tissues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invencion proporciona secuencias de ADN eucarioticas novedosas que codifican para oxidasa de protoporfirinogeno (protox) nativa, o formas modificadas de la enzima que son tolerantes a herbicidas. También se proporcionan plantas que tienen actividad de protox alterada que confiere tolerancia a herbicidas. Estas plantas se pueden reproducir o diseñar para la resistencia a los inhibidores de protoxi por medio de mutacion del gen de protox nativo a una forma resistente, o a través de niveles incrementados de expresion del gen de protox nativo, o se pueden transformar con secuencias de codificacion de protox eucarioticas modificadas, o secuencias de protox procarioticas de tipo silvestre que sean tolerantes a herbicidas. También se describen el diagnostico y otros usos para la secuencia de protox eucariotica novedosa. También se describen genes de plantas que codifican protox de tipo silvestre y alterado, protox de planta purificada, métodos para aislar protox a partir de plantas, y métodos para utilizar los genes codificadores de protox.
MX9606459A 1994-06-16 1995-06-08 MANIPULACION DE ACTIVIDAD DE ENZIMA OXIDASA DE PROTOPORFIRINOGENO EN ORGANISMOS EUCARIaTICOS. MX237061B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26119894A 1994-06-16 1994-06-16
PCT/IB1995/000452 WO1995034659A1 (en) 1994-06-16 1995-06-08 Manipulation of protoporphyrinogen oxidase enzyme activity in eukaryotic organisms

Publications (2)

Publication Number Publication Date
MX9606459A true MX9606459A (es) 1997-03-29
MX237061B MX237061B (es) 2006-05-22

Family

ID=22992309

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9606459A MX237061B (es) 1994-06-16 1995-06-08 MANIPULACION DE ACTIVIDAD DE ENZIMA OXIDASA DE PROTOPORFIRINOGENO EN ORGANISMOS EUCARIaTICOS.

Country Status (24)

Country Link
US (5) US5767373A (es)
EP (1) EP0769059B1 (es)
JP (1) JP3673925B2 (es)
CN (3) CN100432229C (es)
AT (1) ATE296888T1 (es)
AU (2) AU706763B2 (es)
BG (1) BG64394B1 (es)
BR (1) BR9508030A (es)
CA (1) CA2189349C (es)
CZ (2) CZ296023B6 (es)
DE (1) DE69534247T2 (es)
DK (1) DK0769059T3 (es)
ES (1) ES2239757T3 (es)
FI (1) FI964958A0 (es)
HK (1) HK1039794B (es)
HU (1) HUT76353A (es)
MX (1) MX237061B (es)
PL (3) PL183091B1 (es)
PT (1) PT769059E (es)
RO (3) RO122046B1 (es)
RU (2) RU2192468C2 (es)
SK (1) SK284895B6 (es)
UA (1) UA71536C2 (es)
WO (1) WO1995034659A1 (es)

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