MX9302202A - Nueva proteasa fungica. - Google Patents

Nueva proteasa fungica.

Info

Publication number
MX9302202A
MX9302202A MX9302202A MX9302202A MX9302202A MX 9302202 A MX9302202 A MX 9302202A MX 9302202 A MX9302202 A MX 9302202A MX 9302202 A MX9302202 A MX 9302202A MX 9302202 A MX9302202 A MX 9302202A
Authority
MX
Mexico
Prior art keywords
new
protease
subtilisin
serine protease
fungic
Prior art date
Application number
MX9302202A
Other languages
English (en)
Inventor
Frank Buston
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939305097A external-priority patent/GB9305097D0/en
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of MX9302202A publication Critical patent/MX9302202A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/62—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from Aspergillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Detergent Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La presente invención se refiere a una nueva codificación de secuencia de DNA para una proteasa de serina de Aspergillus tipo subtilisina, a la propia proteasa de serina de Aspergillus del tipo de la subtilisina, y a un método para la preparación de la misma. La invención además se refiere a una nueva cepa mutante Aspergillus que carece de una proteasa de serina tipo subtilisina, que es útil para la expresión de proteína heteróloga, y un método para la preparación de esta cepa mutante.
MX9302202A 1992-04-15 1993-04-15 Nueva proteasa fungica. MX9302202A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP92810281 1992-04-15
GB939305097A GB9305097D0 (en) 1993-03-12 1993-03-12 Noval fungal protease

Publications (1)

Publication Number Publication Date
MX9302202A true MX9302202A (es) 1994-04-29

Family

ID=26132501

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9302202A MX9302202A (es) 1992-04-15 1993-04-15 Nueva proteasa fungica.

Country Status (17)

Country Link
EP (1) EP0574347B1 (es)
JP (2) JP3424840B2 (es)
KR (1) KR100270644B1 (es)
AT (1) ATE252156T1 (es)
AU (1) AU663173B2 (es)
CA (1) CA2093950C (es)
CY (1) CY2507B1 (es)
DE (1) DE69333249T2 (es)
DK (1) DK0574347T3 (es)
ES (1) ES2208637T3 (es)
FI (1) FI112667B (es)
HU (1) HU219809B (es)
IL (2) IL170763A (es)
MX (1) MX9302202A (es)
NO (1) NO315379B1 (es)
NZ (1) NZ247397A (es)
PT (1) PT574347E (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5821350A (en) * 1995-11-01 1998-10-13 Nexia Biotechnologies, Inc. Aspergillus niger beta-galactosidase gene
WO1997022705A1 (en) * 1995-12-15 1997-06-26 Novo Nordisk A/S A FUNGUNS WHEREIN THE areA, pepC AND/OR pepE GENES HAVE BEEN INACTIVATED
AU2152897A (en) 1996-03-27 1997-10-17 Novo Nordisk A/S Alkaline protease deficient filamentous fungi
JP2000511429A (ja) * 1996-06-05 2000-09-05 ギスト ブロカデス ベスローテン フェンノートシャップ 真菌メタロプロテアーゼ遺伝子
JPH1016992A (ja) * 1996-07-04 1998-01-20 Toagosei Co Ltd 接着剤用容器
US6806062B1 (en) 1998-10-05 2004-10-19 Novozymes A/S Fungal transcriptional activator useful in methods for producing polypeptides
DE60142226D1 (de) 2000-03-14 2010-07-08 Novozymes As Pilz transkriptionsaktivator zur verwendung in verfahren zur herstellung von polypeptiden
EP1941025B1 (en) 2005-10-17 2011-06-29 Novozymes A/S Use of fungal mutants for expression of antibodies
WO2009071530A1 (en) 2007-12-06 2009-06-11 Novozymes A/S Fungal pepc inhibitor
DK2513290T3 (en) 2009-12-18 2016-01-25 Novozymes Inc Methods for Preparation of Polypeptides in Trichoderma Mutants with Protease Deficiency
MD4186C1 (ro) * 2012-02-20 2013-06-30 Институт Микробиологии И Биотехнологии Академии Наук Молдовы Tulpină de fungi Fusarium gibbosum - producătoare de proteaze acide şi neutre, xilanaze şi b-glucozidaze
KR20160035587A (ko) 2013-07-10 2016-03-31 노파르티스 아게 복수개의 프로테아제 결핍 사상형 진균 세포들 및 그의 이용방법
WO2015025055A1 (en) * 2013-08-23 2015-02-26 Novozymes A/S Regulated pepc expression
CN108064266A (zh) 2014-07-21 2018-05-22 格利科斯芬兰公司 在丝状真菌中具有哺乳动物样n-聚糖的糖蛋白的制备
CN116121151A (zh) * 2023-03-20 2023-05-16 广东溢多利生物科技股份有限公司 黑曲霉突变株anpep15m1及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1333777C (en) * 1988-07-01 1995-01-03 Randy M. Berka Aspartic proteinase deficient filamentous fungi

Also Published As

Publication number Publication date
DK0574347T3 (da) 2004-01-26
DE69333249T2 (de) 2004-07-29
NZ247397A (en) 1995-08-28
IL170763A (en) 2007-10-31
HU9301087D0 (en) 1993-06-28
CA2093950A1 (en) 1993-10-16
FI931634A0 (fi) 1993-04-08
NO315379B1 (no) 2003-08-25
AU3695993A (en) 1993-10-21
JPH0646863A (ja) 1994-02-22
HUT67800A (en) 1995-05-29
NO931368L (no) 1993-10-18
FI112667B (fi) 2003-12-31
AU663173B2 (en) 1995-09-28
JP2003235591A (ja) 2003-08-26
ES2208637T3 (es) 2004-06-16
ATE252156T1 (de) 2003-11-15
EP0574347A2 (en) 1993-12-15
FI931634L (fi) 1993-10-16
KR930021783A (ko) 1993-11-23
JP3424840B2 (ja) 2003-07-07
CA2093950C (en) 2006-05-09
PT574347E (pt) 2004-02-27
EP0574347B1 (en) 2003-10-15
IL105383A0 (en) 1993-08-18
KR100270644B1 (ko) 2000-11-01
DE69333249D1 (de) 2003-11-20
HU219809B (hu) 2001-08-28
CY2507B1 (en) 2005-12-23
NO931368D0 (no) 1993-04-14
JP3636455B2 (ja) 2005-04-06
EP0574347A3 (es) 1994-04-13

Similar Documents

Publication Publication Date Title
MX9302202A (es) Nueva proteasa fungica.
ES2061929T3 (es) Nuevas enzimas proteoliticas y su utilizacion en los detergentes.
DE3686217D1 (de) Alkalische protease, verfahren zur herstellung von hybridvektoren und genetisch transformierte mikroorganismen.
MX9606013A (es) Lacasas purificadas de myceliophthora y acidos nucleicos que codifican para las mismas.
BG49049A3 (bg) Метод за клониране и експресия на гени, кодиращи протеолитични ензими
SG47797A1 (en) Multiply mutated subtilisins
ES2093624T3 (es) Nuevas proteasas muy alcalinas.
ES8800347A1 (es) Metodo para preparar uroquinasa de una sola cadena resistente a proteasas
DE68923123D1 (de) Herstellung von Proteinen.
ES2104596T3 (es) Nuevos polipeptidos, secuencias de adn que permiten su expresion, metodo de preparacion, y utilizacion.
MX9304825A (es) Polipeptidos que poseen una actividad de nitrilasa, codificacion de la secuencia de adn para dichos polipeptidos, cassettes de expresion y microorganismos huesped que les permiten ser obtenidos, y metodo para convertir nitrilos a carboxilatos por med
DK0655497T3 (da) Svampeprotease
DE69737500D1 (de) Von willebrand-faktor multimerase
BR9909147A (pt) Variantes de serina protease com deleções e substituições de aminoácidos
CA2166063A1 (en) Production of trehalose in plants
NZ322796A (en) An apoptotic cysteine protease, mch3 which is a member of ice proteases and nucleic acids encoding mch3
AU4333793A (en) Modified kluyveromyces yeasts, their preparation and use
ES2073174T3 (es) Nuevas proteasas.
DE69834046D1 (de) Extrazelluläre serinprotease
HUP0001284A2 (hu) Humán prohormon konvertáz 4
EP0945512A3 (en) Novel serine proteases
MX9401068A (es) Mejoras en proteasa muy alcalinas que presentan una secuencia de aminoacidos.