MX9300603A - Derivados tiaciclicos de piperidinilo. - Google Patents

Derivados tiaciclicos de piperidinilo.

Info

Publication number
MX9300603A
MX9300603A MX9300603A MX9300603A MX9300603A MX 9300603 A MX9300603 A MX 9300603A MX 9300603 A MX9300603 A MX 9300603A MX 9300603 A MX9300603 A MX 9300603A MX 9300603 A MX9300603 A MX 9300603A
Authority
MX
Mexico
Prior art keywords
derivatives
piperidinyl
thiaciclic
treatment
diseases
Prior art date
Application number
MX9300603A
Other languages
English (en)
Inventor
Albert A Carr
John M Kane
George D Maynard
Hsien C Cheng
Mark W Dudley
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of MX9300603A publication Critical patent/MX9300603A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Derivados tiacíclicos de piperidinilo útiles en el tratamiento de enfermedades alérgicas y de enfermedades que responden al antagonismo de 5HT2, composiciones farmacéuticas y método para el tratamiento mediante el uso de estos compuestos.
MX9300603A 1992-02-13 1993-02-04 Derivados tiaciclicos de piperidinilo. MX9300603A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83565892A 1992-02-13 1992-02-13

Publications (1)

Publication Number Publication Date
MX9300603A true MX9300603A (es) 1993-09-01

Family

ID=25270117

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9300603A MX9300603A (es) 1992-02-13 1993-02-04 Derivados tiaciclicos de piperidinilo.

Country Status (17)

Country Link
US (8) US5371093A (es)
EP (1) EP0626968B1 (es)
JP (1) JP3357879B2 (es)
KR (1) KR100269756B1 (es)
AT (1) ATE206119T1 (es)
AU (1) AU669156B2 (es)
CA (1) CA2129995C (es)
DE (1) DE69330823T2 (es)
DK (1) DK0626968T3 (es)
ES (1) ES2163407T3 (es)
FI (1) FI943727A0 (es)
HU (1) HUT71097A (es)
MX (1) MX9300603A (es)
NO (1) NO305247B1 (es)
NZ (1) NZ249286A (es)
PT (1) PT626968E (es)
WO (1) WO1993016081A1 (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW263504B (es) * 1991-10-03 1995-11-21 Pfizer
US5523308A (en) * 1995-06-07 1996-06-04 Costanzo; Michael J. Peptidyl heterocycles useful in the treatment of thrombin related disorders
US6211199B1 (en) 1995-11-17 2001-04-03 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases
US6194406B1 (en) 1995-12-20 2001-02-27 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
US6423704B2 (en) 1995-12-20 2002-07-23 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
US5922737A (en) * 1996-02-21 1999-07-13 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
US5932571A (en) * 1996-02-21 1999-08-03 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
US5998439A (en) 1996-02-21 1999-12-07 Hoescht Marion Roussel, Inc. Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
US5869497A (en) * 1996-03-15 1999-02-09 Eli Lilly And Company Method of treating or ameliorating the symptoms of common cold or allergic rhinitis
CN1218368A (zh) * 1996-03-15 1999-06-02 伊莱利利公司 治疗感冒或过敏性鼻炎的方法
US5886003A (en) * 1996-03-25 1999-03-23 Eli Lilly And Company Methods of treating or ameliorating the symptoms of venomous bites and stings
GB9725541D0 (en) * 1997-12-02 1998-02-04 Pharmacia & Upjohn Spa Amino-benzothiazole derivatives
ES2165274B1 (es) 1999-06-04 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
DE19939756A1 (de) * 1999-08-21 2001-02-22 Merck Patent Gmbh Piperidinalkohole
JP4859324B2 (ja) * 2000-02-29 2012-01-25 田辺三菱製薬株式会社 新規環状アミド誘導体
ES2172436B1 (es) * 2000-10-31 2004-01-16 Almirall Prodesfarma Sa Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
ES2201907B1 (es) * 2002-05-29 2005-06-01 Almirall Prodesfarma, S.A. Nuevos derivados de indolilpiperidina como potentes agentes antihistaminicos y antialergicos.
GB0306604D0 (en) * 2003-03-21 2003-04-30 Curidium Ltd Second medical use
US7302990B2 (en) * 2004-05-06 2007-12-04 General Electric Company Method of forming concavities in the surface of a metal component, and related processes and articles
NZ554374A (en) * 2004-10-07 2010-11-26 Vitae Pharmaceuticals Inc Diaminoalkane aspartic protease inhibitors
TWI411607B (zh) * 2005-11-14 2013-10-11 Vitae Pharmaceuticals Inc 天門冬胺酸蛋白酶抑制劑
ATE520690T1 (de) * 2006-09-18 2011-09-15 Vitae Pharmaceuticals Inc Piperidinderivate als renin-inhibitoren
CL2007002689A1 (es) 2006-09-18 2008-04-18 Vitae Pharmaceuticals Inc Compuestos derivados de piperidin-1-carboxamida, inhibidores de la renina; compuestos intermediarios; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como hipertension, insuficiencia cardiaca, fibrosis cardiaca, entre otras.
US20100160424A1 (en) * 2007-06-20 2010-06-24 Baldwin John J Renin inhibitors
WO2009096996A1 (en) * 2007-06-20 2009-08-06 Smithkline Beecham Corporation Renin inhibitors
KR101062376B1 (ko) 2008-04-10 2011-09-06 한국화학연구원 신규 인돌 카르복실산 비스피리딜 카르복사마이드 유도체,이의 제조방법 및 이를 유효성분으로 함유하는 조성물
EP2307396A1 (en) * 2008-06-20 2011-04-13 Vitae Pharmaceuticals, Inc. Renin inhibitors and method of use thereof
CA2729052A1 (en) * 2008-06-26 2009-12-30 Vitae Pharmaceuticals, Inc. Salts of methyl 2-((r)-(3-chlorophenyl)((r)-1-((s)-2-(methylamino)-3((r)-tetrahydro-2h-pyran-3-yl)propylcarbamoyl)piperidin-3-yl)methoxy)ethylcarbamate
AR077692A1 (es) * 2009-08-06 2011-09-14 Vitae Pharmaceuticals Inc Sales de 2-((r)-(3-clorofenil) ((r)-1-((s) -2-(metilamino)-3-((r)-tetrahidro-2h-piran-3-il) propilcarbamoil) piperidin -3-il) metoxi) etilcarbamato de metilo

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2526319A (en) * 1946-07-27 1950-10-17 Sprague Electric Co Thienyl ethylene compounds
NL88235C (es) * 1950-12-05
US2739969A (en) * 1952-06-09 1956-03-27 Schering Corp Substituted alkyl piperidines
NL89969C (es) * 1954-02-05
US3122561A (en) * 1959-10-19 1964-02-25 Tuskegee Inst 1-(2-thenyl)-2-di-lower alkylaminoethyl diphenylacetate and related compounds
JPS4831886B1 (es) * 1970-06-11 1973-10-02
DE2131888A1 (de) * 1971-06-24 1972-12-28 Schering Ag 5-Nitrothiazolderivate und Verfahren zu ihrer Herstellung
US3878217A (en) * 1972-01-28 1975-04-15 Richardson Merrell Inc Alpha-aryl-4-substituted piperidinoalkanol derivatives
US3806526A (en) * 1972-01-28 1974-04-23 Richardson Merrell Inc 1-aroylalkyl-4-diphenylmethyl piperidines
US3951998A (en) * 1974-06-17 1976-04-20 Sumitomo Chemical Company, Limited Benzothiazole derivatives
US3966748A (en) * 1975-05-08 1976-06-29 American Cyanamid Company Para-fluorophenyl-N-heterocyclic substituted butanes
US4310465A (en) * 1977-05-17 1982-01-12 Hoffmann-La Roche Inc. Synthesis of vitamin E and quinone intermediates
US4168315A (en) * 1977-09-28 1979-09-18 The Upjohn Company Dianisyl thiazole compound, compositions and method of antithrombotic treatment
US4219559A (en) * 1979-01-10 1980-08-26 Janssen Pharmaceutica N.V. N-Heterocyclyl-4-piperidinamines
JPS6045639B2 (ja) * 1978-05-04 1985-10-11 北陸製薬株式会社 4−(ジチエン−2−イルメチレン)ピペリジン誘導体
US4335127A (en) * 1979-01-08 1982-06-15 Janssen Pharmaceutica, N.V. Piperidinylalkyl quinazoline compounds, composition and method of use
DE3000915A1 (de) * 1979-01-17 1980-07-31 Degussa Neue dithienylpiperidine
DE3000923A1 (de) * 1979-01-17 1980-07-31 Degussa Neue n-alkoxy-dithienylpiperidine
US4254129A (en) * 1979-04-10 1981-03-03 Richardson-Merrell Inc. Piperidine derivatives
US4285957A (en) * 1979-04-10 1981-08-25 Richardson-Merrell Inc. 1-Piperidine-alkanol derivatives, pharmaceutical compositions thereof, and method of use thereof
US4310435A (en) * 1979-12-06 1982-01-12 The Dow Chemical Co. Method and composition for removing sulfide-containing scale from metal surfaces
US4342870A (en) * 1980-03-28 1982-08-03 Janssen Pharmaceutica N.V. Novel 3-(1-piperidinylalkyl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives
JPS6045639A (ja) * 1983-08-19 1985-03-12 日産自動車株式会社 空気噴射式織機の緯入れ装置
DK159420C (da) * 1983-03-09 1991-03-11 Ciba Geigy Ag N-(piperidinyl-alkyl)-carboxamider og salte deraf, farmaceutiske praeparater indeholdende disse forbindelser samt anvendelsen af forbindelserne til fremstilling af antipsykotiske farmaceutiske praeparater
PH23995A (en) * 1984-01-09 1990-02-09 Janssen Pharmaceutica Nv 4((bicycle heterocyclyl)-methyl and hetero)piperidines
US4695575A (en) * 1984-11-13 1987-09-22 Janssen Pharmaceutica, N.V. 4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines
DE3563964D1 (en) * 1984-10-16 1988-09-01 Synthelabo Piperidine derivatives, their preparation and their therapeutical application
US4810713A (en) * 1985-12-20 1989-03-07 A. H. Robins Company, Incorporated Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl groups used in a method for allergy treatment
JPS6393779A (ja) * 1986-10-09 1988-04-25 Toyo Pharma- Kk 4,9−ジヒドロ−4−(1−メチル−4−ピペリジリデン)−10H−ベンゾ〔4,5〕シクロヘプタ〔1,2−b〕チオフエン−10−オン又はその塩の製造方法
DE3877406T2 (de) * 1987-04-28 1993-06-09 Fujisawa Astra Ltd Benzothiazolinon-derivate, ihre herstellung und pharmazeutische zusammensetzung.
JPS63270661A (ja) * 1987-04-28 1988-11-08 Taki Chem Co Ltd 1−〔2−(4−ヒドロキシベンゾイル)エタノイル〕−2−ピペリドン及びその製造法並びにそれを有効成分とするアルコ−ル発酵促進剤
JPS6452776A (en) * 1987-05-18 1989-02-28 Hoe Yakukou Kk Benzothiazolinone derivative
US4876257A (en) * 1988-03-03 1989-10-24 Ortho Pharmaceutical Corporation 6-Substituted purinyl piperazine derivatives useful as cardiotonic and antiarrhythmic agents
JPH01227987A (ja) * 1988-03-08 1989-09-12 Matsushita Electric Ind Co Ltd 人体位置検出装置
ZA894913B (en) * 1988-07-12 1990-03-28 Ici Pharma Heterocyclic compounds
US4908372A (en) * 1988-10-13 1990-03-13 Merrell Dow Pharmaceuticals Inc. Antihistaminic piperidinyl benzimidazoles
JP3003148B2 (ja) * 1989-01-05 2000-01-24 藤沢薬品工業株式会社 チアゾール化合物、その製造法およびそれを含有する医薬組成物
US5089495A (en) * 1989-01-30 1992-02-18 Imperial Chemical Industries Plc Heterocyclic thiazole derivatives and pharmaceutical compositions comprising said derivatives
US5070087A (en) * 1989-05-08 1991-12-03 A. H. Robins Company, Incorporated Aryl(alkyland alkylene)-N-((phenoxy and phenylthio)alkyl) aminoheterocyclics as cardiovascular, anthihistaminic, antisecretory and antiallergy agents
US5064840A (en) * 1989-08-03 1991-11-12 Merrell Dow Pharmaceuticals Anti-psychotic piperidylbenzimidazole compounds
IE903957A1 (en) * 1989-11-06 1991-05-08 Sanofi Sa Aromatic amine compounds, their method of preparation and¹pharmaceutical compositions in which they are present
US5032598A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Nitrogens containing heterocyclic compounds as class III antiarrhythmic agents
US5006536A (en) * 1989-12-26 1991-04-09 Hoechst-Roussel Pharmaceuticals Inc. Thienobenzoxepins and analgesic compositions thereof
JPH03227987A (ja) * 1990-01-30 1991-10-08 Taisho Pharmaceut Co Ltd チアゾール誘導体
CA2093798C (en) * 1990-10-10 2000-02-01 John J. Piwinski Pyridine and pyridine n-oxide derivatives of diaryl methyl piperidines or piperazines, and compositions and methods of use thereof
US5147881A (en) * 1990-11-14 1992-09-15 Pfizer Inc 4-(1,2-benzisoxazolyl)piperidine antipsychotic agents
KR100226954B1 (ko) * 1990-12-14 1999-10-15 슈테펜엘.네스비트 피페리디닐 벤즈이미다졸 유도체, 이를 함유하는 약제학적 조성물 및 이의 제조방법
ES2089815T3 (es) * 1992-03-27 1996-10-01 Schering Corp Derivados de bis-aril-carbinol sin enlaces de puente, composiciones y metodos de uso.
FR2702214B1 (fr) * 1993-03-05 1995-04-14 Adir Nouveaux composés (aryl(alkyl)carbonyl)-hétérocycliques, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
US5384315A (en) * 1994-02-14 1995-01-24 Uniroyal Chemical Company, Inc. Thiophene substituted cycloamines, compositions and use
JPH1052776A (ja) * 1996-08-06 1998-02-24 Toshiba Corp 缶体の溶接方法およびその装置

Also Published As

Publication number Publication date
US5541200A (en) 1996-07-30
AU669156B2 (en) 1996-05-30
FI943727A (fi) 1994-08-12
EP0626968A4 (es) 1995-01-04
US5650416A (en) 1997-07-22
US5602147A (en) 1997-02-11
EP0626968B1 (en) 2001-09-26
ES2163407T3 (es) 2002-02-01
HU9402352D0 (en) 1994-10-28
DE69330823T2 (de) 2002-05-02
HUT71097A (en) 1995-11-28
NZ249286A (en) 1996-02-27
US5371093A (en) 1994-12-06
US5739150A (en) 1998-04-14
US5596003A (en) 1997-01-21
NO942993D0 (no) 1994-08-12
NO942993L (no) 1994-08-12
US5631268A (en) 1997-05-20
CA2129995A1 (en) 1993-08-19
CA2129995C (en) 2000-04-11
AU3585593A (en) 1993-09-03
KR950700309A (ko) 1995-01-16
WO1993016081A1 (en) 1993-08-19
KR100269756B1 (ko) 2000-10-16
EP0626968A1 (en) 1994-12-07
DK0626968T3 (da) 2001-12-31
NO305247B1 (no) 1999-04-26
US5476861A (en) 1995-12-19
FI943727A0 (fi) 1994-08-12
JPH07506346A (ja) 1995-07-13
ATE206119T1 (de) 2001-10-15
JP3357879B2 (ja) 2002-12-16
DE69330823D1 (en) 2001-10-31
PT626968E (pt) 2002-03-28

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