FI943727A0 - Piperidinyylitiasyklisiä johdannaisia - Google Patents

Piperidinyylitiasyklisiä johdannaisia

Info

Publication number
FI943727A0
FI943727A0 FI943727A FI943727A FI943727A0 FI 943727 A0 FI943727 A0 FI 943727A0 FI 943727 A FI943727 A FI 943727A FI 943727 A FI943727 A FI 943727A FI 943727 A0 FI943727 A0 FI 943727A0
Authority
FI
Finland
Prior art keywords
derivatives
piperidinylthiacyclic
treatment
diseases
antagonism
Prior art date
Application number
FI943727A
Other languages
English (en)
Swedish (sv)
Other versions
FI943727A (fi
Inventor
Albert Anthony Carr
John Michael Kane
George David Maynard
Hsien Chang Cheng
Mark William Dudley
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of FI943727A0 publication Critical patent/FI943727A0/fi
Publication of FI943727A publication Critical patent/FI943727A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
FI943727A 1992-02-13 1994-08-12 Piperidinyylitiasyklisiä johdannaisia FI943727A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83565892A 1992-02-13 1992-02-13
PCT/US1993/000448 WO1993016081A1 (en) 1992-02-13 1993-01-15 Piperidinyl thiacyclic derivatives

Publications (2)

Publication Number Publication Date
FI943727A0 true FI943727A0 (fi) 1994-08-12
FI943727A FI943727A (fi) 1994-08-12

Family

ID=25270117

Family Applications (1)

Application Number Title Priority Date Filing Date
FI943727A FI943727A (fi) 1992-02-13 1994-08-12 Piperidinyylitiasyklisiä johdannaisia

Country Status (17)

Country Link
US (8) US5371093A (fi)
EP (1) EP0626968B1 (fi)
JP (1) JP3357879B2 (fi)
KR (1) KR100269756B1 (fi)
AT (1) ATE206119T1 (fi)
AU (1) AU669156B2 (fi)
CA (1) CA2129995C (fi)
DE (1) DE69330823T2 (fi)
DK (1) DK0626968T3 (fi)
ES (1) ES2163407T3 (fi)
FI (1) FI943727A (fi)
HU (1) HUT71097A (fi)
MX (1) MX9300603A (fi)
NO (1) NO305247B1 (fi)
NZ (1) NZ249286A (fi)
PT (1) PT626968E (fi)
WO (1) WO1993016081A1 (fi)

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US6423704B2 (en) 1995-12-20 2002-07-23 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
US6194406B1 (en) 1995-12-20 2001-02-27 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
US5922737A (en) * 1996-02-21 1999-07-13 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
US5932571A (en) * 1996-02-21 1999-08-03 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
US5998439A (en) 1996-02-21 1999-12-07 Hoescht Marion Roussel, Inc. Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
US5869497A (en) * 1996-03-15 1999-02-09 Eli Lilly And Company Method of treating or ameliorating the symptoms of common cold or allergic rhinitis
CA2249652A1 (en) * 1996-03-15 1997-10-02 Eli Lilly And Company Method of treating common cold or allergic rhinitis
US5886003A (en) * 1996-03-25 1999-03-23 Eli Lilly And Company Methods of treating or ameliorating the symptoms of venomous bites and stings
GB9725541D0 (en) * 1997-12-02 1998-02-04 Pharmacia & Upjohn Spa Amino-benzothiazole derivatives
ES2165274B1 (es) 1999-06-04 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
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ES2172436B1 (es) 2000-10-31 2004-01-16 Almirall Prodesfarma Sa Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
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TWI411607B (zh) * 2005-11-14 2013-10-11 Vitae Pharmaceuticals Inc 天門冬胺酸蛋白酶抑制劑
JP2010503682A (ja) * 2006-09-18 2010-02-04 ビテ ファーマシューティカルズ, インコーポレイテッド レニン阻害剤としてのピペリジン誘導体
CL2007002689A1 (es) 2006-09-18 2008-04-18 Vitae Pharmaceuticals Inc Compuestos derivados de piperidin-1-carboxamida, inhibidores de la renina; compuestos intermediarios; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como hipertension, insuficiencia cardiaca, fibrosis cardiaca, entre otras.
US20100317697A1 (en) * 2007-06-20 2010-12-16 Baldwin John J Renin Inhibitors
US20100160424A1 (en) * 2007-06-20 2010-06-24 Baldwin John J Renin inhibitors
KR101062376B1 (ko) * 2008-04-10 2011-09-06 한국화학연구원 신규 인돌 카르복실산 비스피리딜 카르복사마이드 유도체,이의 제조방법 및 이를 유효성분으로 함유하는 조성물
JP2011525488A (ja) * 2008-06-20 2011-09-22 ヴァイティー ファーマシューティカルズ,インコーポレイテッド レニン阻害剤およびその使用方法
US20110112145A1 (en) * 2008-06-26 2011-05-12 Nicole Marie Deschamps Salts Of Methyl 2-((R))-(3-Chlorophenyl)((R)-1-((S)-2-(Methylamino)-3((R)-tetrahydro-2H-Pyran-3-YL)Propylcarbamoyl)Piperidin-3-YL)Methoxy)Ethylcarbamate
AR077692A1 (es) * 2009-08-06 2011-09-14 Vitae Pharmaceuticals Inc Sales de 2-((r)-(3-clorofenil) ((r)-1-((s) -2-(metilamino)-3-((r)-tetrahidro-2h-piran-3-il) propilcarbamoil) piperidin -3-il) metoxi) etilcarbamato de metilo

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Also Published As

Publication number Publication date
ES2163407T3 (es) 2002-02-01
HUT71097A (en) 1995-11-28
NZ249286A (en) 1996-02-27
US5541200A (en) 1996-07-30
JPH07506346A (ja) 1995-07-13
HU9402352D0 (en) 1994-10-28
US5631268A (en) 1997-05-20
US5371093A (en) 1994-12-06
CA2129995C (en) 2000-04-11
MX9300603A (es) 1993-09-01
NO942993L (no) 1994-08-12
US5476861A (en) 1995-12-19
US5602147A (en) 1997-02-11
AU3585593A (en) 1993-09-03
EP0626968B1 (en) 2001-09-26
DK0626968T3 (da) 2001-12-31
WO1993016081A1 (en) 1993-08-19
DE69330823D1 (en) 2001-10-31
DE69330823T2 (de) 2002-05-02
FI943727A (fi) 1994-08-12
KR950700309A (ko) 1995-01-16
AU669156B2 (en) 1996-05-30
NO305247B1 (no) 1999-04-26
KR100269756B1 (ko) 2000-10-16
US5739150A (en) 1998-04-14
EP0626968A1 (en) 1994-12-07
CA2129995A1 (en) 1993-08-19
NO942993D0 (no) 1994-08-12
US5596003A (en) 1997-01-21
PT626968E (pt) 2002-03-28
ATE206119T1 (de) 2001-10-15
JP3357879B2 (ja) 2002-12-16
EP0626968A4 (fi) 1995-01-04
US5650416A (en) 1997-07-22

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