ATE206119T1 - Thiacyclische piperidinylderivate - Google Patents

Thiacyclische piperidinylderivate

Info

Publication number
ATE206119T1
ATE206119T1 AT93904527T AT93904527T ATE206119T1 AT E206119 T1 ATE206119 T1 AT E206119T1 AT 93904527 T AT93904527 T AT 93904527T AT 93904527 T AT93904527 T AT 93904527T AT E206119 T1 ATE206119 T1 AT E206119T1
Authority
AT
Austria
Prior art keywords
thiacyclic
piperidinyl derivatives
treatment
derivatives
piperidinyl
Prior art date
Application number
AT93904527T
Other languages
English (en)
Inventor
Albert A Carr
John M Kane
George D Maynard
Hsien C Cheng
Mark W Dudley
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Application granted granted Critical
Publication of ATE206119T1 publication Critical patent/ATE206119T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT93904527T 1992-02-13 1993-01-15 Thiacyclische piperidinylderivate ATE206119T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83565892A 1992-02-13 1992-02-13
PCT/US1993/000448 WO1993016081A1 (en) 1992-02-13 1993-01-15 Piperidinyl thiacyclic derivatives

Publications (1)

Publication Number Publication Date
ATE206119T1 true ATE206119T1 (de) 2001-10-15

Family

ID=25270117

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93904527T ATE206119T1 (de) 1992-02-13 1993-01-15 Thiacyclische piperidinylderivate

Country Status (17)

Country Link
US (8) US5371093A (de)
EP (1) EP0626968B1 (de)
JP (1) JP3357879B2 (de)
KR (1) KR100269756B1 (de)
AT (1) ATE206119T1 (de)
AU (1) AU669156B2 (de)
CA (1) CA2129995C (de)
DE (1) DE69330823T2 (de)
DK (1) DK0626968T3 (de)
ES (1) ES2163407T3 (de)
FI (1) FI943727A (de)
HU (1) HUT71097A (de)
MX (1) MX9300603A (de)
NO (1) NO305247B1 (de)
NZ (1) NZ249286A (de)
PT (1) PT626968E (de)
WO (1) WO1993016081A1 (de)

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US6194406B1 (en) 1995-12-20 2001-02-27 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
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US5922737A (en) * 1996-02-21 1999-07-13 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
US5998439A (en) * 1996-02-21 1999-12-07 Hoescht Marion Roussel, Inc. Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
US5869497A (en) * 1996-03-15 1999-02-09 Eli Lilly And Company Method of treating or ameliorating the symptoms of common cold or allergic rhinitis
EA199800858A1 (ru) * 1996-03-15 1999-02-25 Эли Лилли Энд Компани Способ лечения насморка или аллергического ринита
US5886003A (en) * 1996-03-25 1999-03-23 Eli Lilly And Company Methods of treating or ameliorating the symptoms of venomous bites and stings
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US20100317697A1 (en) * 2007-06-20 2010-12-16 Baldwin John J Renin Inhibitors
KR101062376B1 (ko) * 2008-04-10 2011-09-06 한국화학연구원 신규 인돌 카르복실산 비스피리딜 카르복사마이드 유도체,이의 제조방법 및 이를 유효성분으로 함유하는 조성물
MX2010014146A (es) * 2008-06-20 2011-01-21 Vitae Pharmaceuticals Inc Inhibidores de renina y metodo de uso de los mismos.
CN102088850A (zh) * 2008-06-26 2011-06-08 生命医药公司 甲基2-((r)-(3-氯苯基)((r)-1-((s)-2-(甲氨基)-3((r)-四氢-2h-吡喃-3-基)丙基氨甲酰基)哌啶-3-基)甲氧基)氨基甲酸乙酯的盐
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Also Published As

Publication number Publication date
NO942993L (no) 1994-08-12
KR950700309A (ko) 1995-01-16
US5631268A (en) 1997-05-20
US5371093A (en) 1994-12-06
JPH07506346A (ja) 1995-07-13
HU9402352D0 (en) 1994-10-28
NZ249286A (en) 1996-02-27
EP0626968B1 (de) 2001-09-26
JP3357879B2 (ja) 2002-12-16
HUT71097A (en) 1995-11-28
US5739150A (en) 1998-04-14
NO942993D0 (no) 1994-08-12
DK0626968T3 (da) 2001-12-31
NO305247B1 (no) 1999-04-26
FI943727A0 (fi) 1994-08-12
KR100269756B1 (ko) 2000-10-16
MX9300603A (es) 1993-09-01
US5476861A (en) 1995-12-19
US5602147A (en) 1997-02-11
US5650416A (en) 1997-07-22
AU669156B2 (en) 1996-05-30
EP0626968A1 (de) 1994-12-07
PT626968E (pt) 2002-03-28
AU3585593A (en) 1993-09-03
DE69330823D1 (en) 2001-10-31
CA2129995C (en) 2000-04-11
EP0626968A4 (de) 1995-01-04
DE69330823T2 (de) 2002-05-02
US5541200A (en) 1996-07-30
US5596003A (en) 1997-01-21
ES2163407T3 (es) 2002-02-01
WO1993016081A1 (en) 1993-08-19
CA2129995A1 (en) 1993-08-19
FI943727A (fi) 1994-08-12

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