NO942993L - Piperidinyltiasykliske derivater - Google Patents

Piperidinyltiasykliske derivater

Info

Publication number
NO942993L
NO942993L NO942993A NO942993A NO942993L NO 942993 L NO942993 L NO 942993L NO 942993 A NO942993 A NO 942993A NO 942993 A NO942993 A NO 942993A NO 942993 L NO942993 L NO 942993L
Authority
NO
Norway
Prior art keywords
derivatives
piperidinylthiazyclic
treatment
diseases
antagonism
Prior art date
Application number
NO942993A
Other languages
English (en)
Other versions
NO305247B1 (no
NO942993D0 (no
Inventor
Albert Anthony Carr
John Michael Kane
George David Maynard
Hsien Chang Cheng
Mark William Dudley
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of NO942993L publication Critical patent/NO942993L/no
Publication of NO942993D0 publication Critical patent/NO942993D0/no
Publication of NO305247B1 publication Critical patent/NO305247B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
NO942993A 1992-02-13 1994-08-12 Piperidinyltiasykliske derivater NO305247B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83565892A 1992-02-13 1992-02-13
PCT/US1993/000448 WO1993016081A1 (en) 1992-02-13 1993-01-15 Piperidinyl thiacyclic derivatives

Publications (3)

Publication Number Publication Date
NO942993L true NO942993L (no) 1994-08-12
NO942993D0 NO942993D0 (no) 1994-08-12
NO305247B1 NO305247B1 (no) 1999-04-26

Family

ID=25270117

Family Applications (1)

Application Number Title Priority Date Filing Date
NO942993A NO305247B1 (no) 1992-02-13 1994-08-12 Piperidinyltiasykliske derivater

Country Status (17)

Country Link
US (8) US5371093A (no)
EP (1) EP0626968B1 (no)
JP (1) JP3357879B2 (no)
KR (1) KR100269756B1 (no)
AT (1) ATE206119T1 (no)
AU (1) AU669156B2 (no)
CA (1) CA2129995C (no)
DE (1) DE69330823T2 (no)
DK (1) DK0626968T3 (no)
ES (1) ES2163407T3 (no)
FI (1) FI943727A0 (no)
HU (1) HUT71097A (no)
MX (1) MX9300603A (no)
NO (1) NO305247B1 (no)
NZ (1) NZ249286A (no)
PT (1) PT626968E (no)
WO (1) WO1993016081A1 (no)

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US6194406B1 (en) 1995-12-20 2001-02-27 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
US5932571A (en) * 1996-02-21 1999-08-03 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
US5998439A (en) * 1996-02-21 1999-12-07 Hoescht Marion Roussel, Inc. Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
US5922737A (en) * 1996-02-21 1999-07-13 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
WO1997035480A1 (en) * 1996-03-15 1997-10-02 Eli Lilly And Company Method of treating common cold or allergic rhinitis
US5869497A (en) * 1996-03-15 1999-02-09 Eli Lilly And Company Method of treating or ameliorating the symptoms of common cold or allergic rhinitis
US5886003A (en) * 1996-03-25 1999-03-23 Eli Lilly And Company Methods of treating or ameliorating the symptoms of venomous bites and stings
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DE19939756A1 (de) * 1999-08-21 2001-02-22 Merck Patent Gmbh Piperidinalkohole
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ES2172436B1 (es) * 2000-10-31 2004-01-16 Almirall Prodesfarma Sa Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
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TWI411607B (zh) * 2005-11-14 2013-10-11 Vitae Pharmaceuticals Inc 天門冬胺酸蛋白酶抑制劑
WO2008036216A1 (en) * 2006-09-18 2008-03-27 Vitae Pharmaceuticals, Inc. Piperidine derivatives as renin inhibitors
CL2007002689A1 (es) 2006-09-18 2008-04-18 Vitae Pharmaceuticals Inc Compuestos derivados de piperidin-1-carboxamida, inhibidores de la renina; compuestos intermediarios; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como hipertension, insuficiencia cardiaca, fibrosis cardiaca, entre otras.
US20100160424A1 (en) * 2007-06-20 2010-06-24 Baldwin John J Renin inhibitors
EP2167609A1 (en) * 2007-06-20 2010-03-31 Vitae Pharmaceuticals, Inc. Renin inhibitors
KR101062376B1 (ko) * 2008-04-10 2011-09-06 한국화학연구원 신규 인돌 카르복실산 비스피리딜 카르복사마이드 유도체,이의 제조방법 및 이를 유효성분으로 함유하는 조성물
EP2307396A1 (en) * 2008-06-20 2011-04-13 Vitae Pharmaceuticals, Inc. Renin inhibitors and method of use thereof
CA2729052A1 (en) * 2008-06-26 2009-12-30 Vitae Pharmaceuticals, Inc. Salts of methyl 2-((r)-(3-chlorophenyl)((r)-1-((s)-2-(methylamino)-3((r)-tetrahydro-2h-pyran-3-yl)propylcarbamoyl)piperidin-3-yl)methoxy)ethylcarbamate
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Also Published As

Publication number Publication date
US5739150A (en) 1998-04-14
FI943727A (fi) 1994-08-12
EP0626968B1 (en) 2001-09-26
US5650416A (en) 1997-07-22
US5541200A (en) 1996-07-30
US5602147A (en) 1997-02-11
NZ249286A (en) 1996-02-27
US5596003A (en) 1997-01-21
CA2129995C (en) 2000-04-11
HUT71097A (en) 1995-11-28
DE69330823T2 (de) 2002-05-02
JPH07506346A (ja) 1995-07-13
WO1993016081A1 (en) 1993-08-19
NO305247B1 (no) 1999-04-26
US5631268A (en) 1997-05-20
DK0626968T3 (da) 2001-12-31
PT626968E (pt) 2002-03-28
HU9402352D0 (en) 1994-10-28
US5371093A (en) 1994-12-06
NO942993D0 (no) 1994-08-12
KR100269756B1 (ko) 2000-10-16
KR950700309A (ko) 1995-01-16
JP3357879B2 (ja) 2002-12-16
AU3585593A (en) 1993-09-03
ATE206119T1 (de) 2001-10-15
EP0626968A4 (no) 1995-01-04
AU669156B2 (en) 1996-05-30
EP0626968A1 (en) 1994-12-07
MX9300603A (es) 1993-09-01
CA2129995A1 (en) 1993-08-19
FI943727A0 (fi) 1994-08-12
ES2163407T3 (es) 2002-02-01
US5476861A (en) 1995-12-19
DE69330823D1 (en) 2001-10-31

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