NO305247B1 - Piperidinyltiasykliske derivater - Google Patents

Piperidinyltiasykliske derivater

Info

Publication number
NO305247B1
NO305247B1 NO942993A NO942993A NO305247B1 NO 305247 B1 NO305247 B1 NO 305247B1 NO 942993 A NO942993 A NO 942993A NO 942993 A NO942993 A NO 942993A NO 305247 B1 NO305247 B1 NO 305247B1
Authority
NO
Norway
Prior art keywords
derivatives
piperidinylthiazyclic
treatment
diseases
antagonism
Prior art date
Application number
NO942993A
Other languages
English (en)
Other versions
NO942993D0 (no
NO942993L (no
Inventor
Albert Anthony Carr
John Michael Kane
George David Maynard
Hsien Chang Cheng
Mark William Dudley
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of NO942993D0 publication Critical patent/NO942993D0/no
Publication of NO942993L publication Critical patent/NO942993L/no
Publication of NO305247B1 publication Critical patent/NO305247B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
NO942993A 1992-02-13 1994-08-12 Piperidinyltiasykliske derivater NO305247B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83565892A 1992-02-13 1992-02-13
PCT/US1993/000448 WO1993016081A1 (en) 1992-02-13 1993-01-15 Piperidinyl thiacyclic derivatives

Publications (3)

Publication Number Publication Date
NO942993D0 NO942993D0 (no) 1994-08-12
NO942993L NO942993L (no) 1994-08-12
NO305247B1 true NO305247B1 (no) 1999-04-26

Family

ID=25270117

Family Applications (1)

Application Number Title Priority Date Filing Date
NO942993A NO305247B1 (no) 1992-02-13 1994-08-12 Piperidinyltiasykliske derivater

Country Status (17)

Country Link
US (8) US5371093A (no)
EP (1) EP0626968B1 (no)
JP (1) JP3357879B2 (no)
KR (1) KR100269756B1 (no)
AT (1) ATE206119T1 (no)
AU (1) AU669156B2 (no)
CA (1) CA2129995C (no)
DE (1) DE69330823T2 (no)
DK (1) DK0626968T3 (no)
ES (1) ES2163407T3 (no)
FI (1) FI943727A0 (no)
HU (1) HUT71097A (no)
MX (1) MX9300603A (no)
NO (1) NO305247B1 (no)
NZ (1) NZ249286A (no)
PT (1) PT626968E (no)
WO (1) WO1993016081A1 (no)

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US6194406B1 (en) 1995-12-20 2001-02-27 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
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US5932571A (en) * 1996-02-21 1999-08-03 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
US5998439A (en) 1996-02-21 1999-12-07 Hoescht Marion Roussel, Inc. Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
JP2000507269A (ja) * 1996-03-15 2000-06-13 イーライ・リリー・アンド・カンパニー 一般かぜまたはアレルギー性鼻炎の処置方法
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CL2007002689A1 (es) * 2006-09-18 2008-04-18 Vitae Pharmaceuticals Inc Compuestos derivados de piperidin-1-carboxamida, inhibidores de la renina; compuestos intermediarios; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como hipertension, insuficiencia cardiaca, fibrosis cardiaca, entre otras.
EP2167609A1 (en) * 2007-06-20 2010-03-31 Vitae Pharmaceuticals, Inc. Renin inhibitors
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KR101062376B1 (ko) * 2008-04-10 2011-09-06 한국화학연구원 신규 인돌 카르복실산 비스피리딜 카르복사마이드 유도체,이의 제조방법 및 이를 유효성분으로 함유하는 조성물
US20110160300A1 (en) * 2008-06-20 2011-06-30 Marlys Hammond Renin Inhibitors and Methods of Use Thereof
WO2009158377A1 (en) * 2008-06-26 2009-12-30 Smith Kline Beecham Corporation Salts of methyl 2-((r))-(3-chlorophenyl)((r)-1-((s)-2-(methylamino)-3((r)-tetrahydro-2h-pyran-3-yl)propylcarbamoyl)piperidin-3-yl)methoxy)ethylcarbamate
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Also Published As

Publication number Publication date
HU9402352D0 (en) 1994-10-28
US5631268A (en) 1997-05-20
EP0626968A4 (no) 1995-01-04
FI943727A (fi) 1994-08-12
AU3585593A (en) 1993-09-03
NO942993D0 (no) 1994-08-12
US5650416A (en) 1997-07-22
US5541200A (en) 1996-07-30
US5602147A (en) 1997-02-11
US5596003A (en) 1997-01-21
US5371093A (en) 1994-12-06
FI943727A0 (fi) 1994-08-12
KR100269756B1 (ko) 2000-10-16
ES2163407T3 (es) 2002-02-01
CA2129995C (en) 2000-04-11
HUT71097A (en) 1995-11-28
PT626968E (pt) 2002-03-28
WO1993016081A1 (en) 1993-08-19
DE69330823D1 (en) 2001-10-31
EP0626968B1 (en) 2001-09-26
AU669156B2 (en) 1996-05-30
DE69330823T2 (de) 2002-05-02
EP0626968A1 (en) 1994-12-07
JPH07506346A (ja) 1995-07-13
ATE206119T1 (de) 2001-10-15
CA2129995A1 (en) 1993-08-19
KR950700309A (ko) 1995-01-16
NO942993L (no) 1994-08-12
US5739150A (en) 1998-04-14
NZ249286A (en) 1996-02-27
JP3357879B2 (ja) 2002-12-16
US5476861A (en) 1995-12-19
DK0626968T3 (da) 2001-12-31
MX9300603A (es) 1993-09-01

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