JPS6452776A - Benzothiazolinone derivative - Google Patents
Benzothiazolinone derivativeInfo
- Publication number
- JPS6452776A JPS6452776A JP10956088A JP10956088A JPS6452776A JP S6452776 A JPS6452776 A JP S6452776A JP 10956088 A JP10956088 A JP 10956088A JP 10956088 A JP10956088 A JP 10956088A JP S6452776 A JPS6452776 A JP S6452776A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound expressed
- hydroxy
- halogen
- expressed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A benzothiazolinone derivative expressed by formula I (A is lower alkylene; X is halogen; R<1> is H and R<2> is lower alkoxy or aralkyloxy or R<1> is hydroxy and R<2> is hydroxy or halogen-substituted aryl or R<1> and R<2> together are lower alkylenedioxy). EXAMPLE:5-Chloro-3-(4-methoxypiperidinocarbonylmethyl)benzothiazolin-2 -one. USE:Useful as a medicine for treating bronchial asthma, allergic rhinitis, inflammatory disease, dermatosis and diseases caused by thrombogenesis in a brain, heart, etc., having antiallergic and anti-inflammatory action,. PREPARATION:A compound expressed by formula II is reacted with a compound expressed by formula III in a solvent, such as ethanol, preferably in the presence of a condensing agent to afford the aimed compound expressed by formula I.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10956088A JPS6452776A (en) | 1987-05-18 | 1988-05-02 | Benzothiazolinone derivative |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12078587 | 1987-05-18 | ||
JP10956088A JPS6452776A (en) | 1987-05-18 | 1988-05-02 | Benzothiazolinone derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6452776A true JPS6452776A (en) | 1989-02-28 |
Family
ID=26449298
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10956088A Pending JPS6452776A (en) | 1987-05-18 | 1988-05-02 | Benzothiazolinone derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6452776A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993016081A1 (en) * | 1992-02-13 | 1993-08-19 | Merrell Dow Pharmaceuticals Inc. | Piperidinyl thiacyclic derivatives |
WO1997043282A3 (en) * | 1996-05-10 | 1998-01-29 | Klinge Co Chem Pharm Fab | Benzothiazolinones as anti-asthmatic agents |
-
1988
- 1988-05-02 JP JP10956088A patent/JPS6452776A/en active Pending
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993016081A1 (en) * | 1992-02-13 | 1993-08-19 | Merrell Dow Pharmaceuticals Inc. | Piperidinyl thiacyclic derivatives |
US5371093A (en) * | 1992-02-13 | 1994-12-06 | Merrell Dow Pharmaceuticals Inc. | Piperidinyl thiacyclic derivatives |
US5476861A (en) * | 1992-02-13 | 1995-12-19 | Merrell Dow Pharmaceuricals Inc. | Piperidinyl thiacyclic derivatives |
AU669156B2 (en) * | 1992-02-13 | 1996-05-30 | Merrell Dow Pharmaceuticals Inc. | Piperidinyl thiacyclic derivatives |
US5596003A (en) * | 1992-02-13 | 1997-01-21 | Merrell Pharmaceuticals Inc. | Piperidinyl thiacyclic derivatives |
WO1997043282A3 (en) * | 1996-05-10 | 1998-01-29 | Klinge Co Chem Pharm Fab | Benzothiazolinones as anti-asthmatic agents |
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