JPS6452776A - Benzothiazolinone derivative - Google Patents

Benzothiazolinone derivative

Info

Publication number
JPS6452776A
JPS6452776A JP10956088A JP10956088A JPS6452776A JP S6452776 A JPS6452776 A JP S6452776A JP 10956088 A JP10956088 A JP 10956088A JP 10956088 A JP10956088 A JP 10956088A JP S6452776 A JPS6452776 A JP S6452776A
Authority
JP
Japan
Prior art keywords
formula
compound expressed
hydroxy
halogen
expressed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10956088A
Other languages
Japanese (ja)
Inventor
Suminori Kaio
Shizuo Ozasa
Takahiro Yabuuchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HOE YAKUKOU KK
Research Institute for Production Development
Original Assignee
HOE YAKUKOU KK
Research Institute for Production Development
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HOE YAKUKOU KK, Research Institute for Production Development filed Critical HOE YAKUKOU KK
Priority to JP10956088A priority Critical patent/JPS6452776A/en
Publication of JPS6452776A publication Critical patent/JPS6452776A/en
Pending legal-status Critical Current

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A benzothiazolinone derivative expressed by formula I (A is lower alkylene; X is halogen; R<1> is H and R<2> is lower alkoxy or aralkyloxy or R<1> is hydroxy and R<2> is hydroxy or halogen-substituted aryl or R<1> and R<2> together are lower alkylenedioxy). EXAMPLE:5-Chloro-3-(4-methoxypiperidinocarbonylmethyl)benzothiazolin-2 -one. USE:Useful as a medicine for treating bronchial asthma, allergic rhinitis, inflammatory disease, dermatosis and diseases caused by thrombogenesis in a brain, heart, etc., having antiallergic and anti-inflammatory action,. PREPARATION:A compound expressed by formula II is reacted with a compound expressed by formula III in a solvent, such as ethanol, preferably in the presence of a condensing agent to afford the aimed compound expressed by formula I.
JP10956088A 1987-05-18 1988-05-02 Benzothiazolinone derivative Pending JPS6452776A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10956088A JPS6452776A (en) 1987-05-18 1988-05-02 Benzothiazolinone derivative

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP12078587 1987-05-18
JP10956088A JPS6452776A (en) 1987-05-18 1988-05-02 Benzothiazolinone derivative

Publications (1)

Publication Number Publication Date
JPS6452776A true JPS6452776A (en) 1989-02-28

Family

ID=26449298

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10956088A Pending JPS6452776A (en) 1987-05-18 1988-05-02 Benzothiazolinone derivative

Country Status (1)

Country Link
JP (1) JPS6452776A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993016081A1 (en) * 1992-02-13 1993-08-19 Merrell Dow Pharmaceuticals Inc. Piperidinyl thiacyclic derivatives
WO1997043282A3 (en) * 1996-05-10 1998-01-29 Klinge Co Chem Pharm Fab Benzothiazolinones as anti-asthmatic agents

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993016081A1 (en) * 1992-02-13 1993-08-19 Merrell Dow Pharmaceuticals Inc. Piperidinyl thiacyclic derivatives
US5371093A (en) * 1992-02-13 1994-12-06 Merrell Dow Pharmaceuticals Inc. Piperidinyl thiacyclic derivatives
US5476861A (en) * 1992-02-13 1995-12-19 Merrell Dow Pharmaceuricals Inc. Piperidinyl thiacyclic derivatives
AU669156B2 (en) * 1992-02-13 1996-05-30 Merrell Dow Pharmaceuticals Inc. Piperidinyl thiacyclic derivatives
US5596003A (en) * 1992-02-13 1997-01-21 Merrell Pharmaceuticals Inc. Piperidinyl thiacyclic derivatives
WO1997043282A3 (en) * 1996-05-10 1998-01-29 Klinge Co Chem Pharm Fab Benzothiazolinones as anti-asthmatic agents

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