MX9100312A - Derivados de oxazolilo novedosos - Google Patents

Derivados de oxazolilo novedosos

Info

Publication number
MX9100312A
MX9100312A MX9100312A MX9100312A MX9100312A MX 9100312 A MX9100312 A MX 9100312A MX 9100312 A MX9100312 A MX 9100312A MX 9100312 A MX9100312 A MX 9100312A MX 9100312 A MX9100312 A MX 9100312A
Authority
MX
Mexico
Prior art keywords
noxed
oxazolyl derivatives
oxazolyl
derivatives
noxed oxazolyl
Prior art date
Application number
MX9100312A
Other languages
English (en)
Inventor
Frans Eduard Janssens
Francois Maria Sommen
Ann Christina Joannes Dierckx
Ludwig Paul Cooymans
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of MX9100312A publication Critical patent/MX9100312A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/26Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32Nitrogen atom
    • C07D473/34Nitrogen atom attached in position 6, e.g. adenine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
MX9100312A 1990-07-19 1991-07-19 Derivados de oxazolilo novedosos MX9100312A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55432690A 1990-07-19 1990-07-19

Publications (1)

Publication Number Publication Date
MX9100312A true MX9100312A (es) 1992-02-28

Family

ID=24212929

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9100312A MX9100312A (es) 1990-07-19 1991-07-19 Derivados de oxazolilo novedosos

Country Status (31)

Country Link
EP (1) EP0539421B1 (es)
JP (1) JP3070951B2 (es)
KR (1) KR100190299B1 (es)
CN (1) CN1043640C (es)
AP (1) AP267A (es)
AT (1) ATE171449T1 (es)
AU (1) AU644202B2 (es)
BG (1) BG61342B1 (es)
CA (1) CA2086545A1 (es)
CZ (1) CZ279344B6 (es)
DE (1) DE69130255T2 (es)
ES (1) ES2121784T3 (es)
FI (1) FI930198A0 (es)
HU (1) HUT64340A (es)
IE (1) IE912532A1 (es)
IL (1) IL98864A (es)
MA (1) MA22226A1 (es)
MX (1) MX9100312A (es)
MY (1) MY107973A (es)
NO (1) NO300459B1 (es)
NZ (1) NZ238864A (es)
PL (1) PL169361B1 (es)
PT (1) PT98365B (es)
RO (1) RO111768B1 (es)
RU (1) RU2059636C1 (es)
SK (1) SK278133B6 (es)
TN (1) TNSN91062A1 (es)
TW (1) TW235964B (es)
WO (1) WO1992001687A1 (es)
YU (1) YU126391A (es)
ZA (1) ZA915653B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW222274B (es) * 1992-01-09 1994-04-11 Janssen Pharmaceutica Nv
US6211199B1 (en) 1995-11-17 2001-04-03 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases
US6423704B2 (en) 1995-12-20 2002-07-23 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
US6194406B1 (en) 1995-12-20 2001-02-27 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
US5922737A (en) * 1996-02-21 1999-07-13 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
US5998439A (en) * 1996-02-21 1999-12-07 Hoescht Marion Roussel, Inc. Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
US5932571A (en) * 1996-02-21 1999-08-03 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
JP2003503403A (ja) 1999-06-28 2003-01-28 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 呼吸合胞体ウイルス複製阻害剤
DE60013836T2 (de) 1999-06-28 2006-01-19 Janssen Pharmaceutica N.V. Replikationsinhibitoren des respiratorischen synzytialvirus
TR200103806T2 (tr) 1999-06-28 2002-06-21 Janssen Pharmaceutica N. V. Solunum sistemi sinsitiyal virüsünün replikasyonunu inhibe edici maddeler.
GB0315203D0 (en) * 2003-06-28 2003-08-06 Celltech R&D Ltd Chemical compounds
WO2005058874A1 (en) 2003-12-18 2005-06-30 Tibotec Pharmaceuticals Ltd. 5- or 6-substituted benzimidazole derivatives as inhibitors of respiratory syncytial virus replication
AR046771A1 (es) * 2003-12-18 2005-12-21 Tibotec Pharm Ltd Derivados piperidina-amino-bencimidazol como inhibidores de la replicacion del virus sincitial respiratorio
US8044073B2 (en) 2003-12-18 2011-10-25 Tibotec Pharmaceuticals Aminobenzimidazoles and benzimidazoles as inhibitors of respiratory syncytial virus replication
US7855194B2 (en) 2006-03-27 2010-12-21 Hoffmann-La Roche Inc. Pyrimidine, quinazoline, pteridine and triazine derivatives
TWI377511B (en) 2008-12-05 2012-11-21 Ind Tech Res Inst Flame detecting method and system
CN104098609B (zh) * 2014-07-28 2016-08-17 陕西科技大学 含二茂铁的咪唑并[2,1-b]-1,3,4-噻二唑、制备方法及其应用
EP3233799B1 (en) 2014-12-19 2021-05-19 The Broad Institute, Inc. Dopamine d2 receptor ligands
US10633336B2 (en) 2014-12-19 2020-04-28 The Broad Institute, Inc. Dopamine D2 receptor ligands

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4556660A (en) * 1982-07-12 1985-12-03 Janssen Pharmaceutica N.V. N-(Bicyclic heterocyclyl)-4-piperidinamines
US4634704A (en) * 1983-10-06 1987-01-06 Janssen Pharmaceutica, N.V. Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines
US4695569A (en) * 1983-11-30 1987-09-22 Janssen Pharmaceutica N.V. Bicyclic heterocyclyl containing N-(bicyclic heterocyclyl)-4-piperidinamines
US4588722A (en) * 1984-01-09 1986-05-13 Janssen Pharmaceutica N.V. N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives
PH23995A (en) * 1984-01-09 1990-02-09 Janssen Pharmaceutica Nv 4((bicycle heterocyclyl)-methyl and hetero)piperidines
KR930005004B1 (ko) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법
GB8515934D0 (en) * 1985-06-24 1985-07-24 Janssen Pharmaceutica Nv (4-piperidinomethyl and-hetero)purines
US4835161A (en) * 1986-02-03 1989-05-30 Janssen Pharmaceutica N.V. Anti-histaminic compositions containing n-heterocyclyl-4-piperidinamines
US4897401A (en) * 1987-06-19 1990-01-30 Janssen Pharmaceutical N.V. N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives useful in treating allergic diseases
CA1317939C (en) * 1987-07-01 1993-05-18 Janssen Pharmaceutica Naamloze Vennootschap ¬(bicyclic heterocyclyl)methyl and -hetero| substituted hexahydro-1h-azepines and pyrrolidines

Also Published As

Publication number Publication date
IE912532A1 (en) 1992-01-29
TNSN91062A1 (fr) 1992-10-25
EP0539421A1 (en) 1993-05-05
FI930198A (fi) 1993-01-18
BG61342B1 (en) 1997-06-30
MY107973A (en) 1996-07-15
KR100190299B1 (ko) 1999-06-01
YU126391A (sh) 1994-06-10
RU2059636C1 (ru) 1996-05-10
NO930156L (no) 1993-01-18
IL98864A (en) 1995-12-08
RO111768B1 (ro) 1997-01-30
PT98365B (pt) 1999-01-29
AP9100298A0 (en) 1991-07-31
NO930156D0 (no) 1993-01-18
DE69130255T2 (de) 1999-04-08
CA2086545A1 (en) 1992-01-20
HUT64340A (en) 1993-12-28
DE69130255D1 (de) 1998-10-29
AU8214191A (en) 1992-02-18
CN1058215A (zh) 1992-01-29
NO300459B1 (no) 1997-06-02
ZA915653B (en) 1993-03-31
ATE171449T1 (de) 1998-10-15
AP267A (en) 1993-06-16
PT98365A (pt) 1992-05-29
SK278133B6 (en) 1996-02-07
AU644202B2 (en) 1993-12-02
JP3070951B2 (ja) 2000-07-31
PL169361B1 (pl) 1996-07-31
HU9300097D0 (en) 1993-04-28
IL98864A0 (en) 1992-07-15
EP0539421B1 (en) 1998-09-23
JPH05508839A (ja) 1993-12-09
FI930198A0 (fi) 1993-01-18
BG97314A (bg) 1994-01-24
CZ279344B6 (cs) 1995-04-12
MA22226A1 (fr) 1992-04-01
TW235964B (es) 1994-12-11
CN1043640C (zh) 1999-06-16
NZ238864A (en) 1993-08-26
CS224091A3 (en) 1992-02-19
ES2121784T3 (es) 1998-12-16
PL297611A1 (es) 1992-07-13
WO1992001687A1 (en) 1992-02-06

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees