MX366793B - Metodos para preparar oxazolidinonas y composiciones que las contienen. - Google Patents
Metodos para preparar oxazolidinonas y composiciones que las contienen.Info
- Publication number
- MX366793B MX366793B MX2014004600A MX2014004600A MX366793B MX 366793 B MX366793 B MX 366793B MX 2014004600 A MX2014004600 A MX 2014004600A MX 2014004600 A MX2014004600 A MX 2014004600A MX 366793 B MX366793 B MX 366793B
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- compositions containing
- preparing
- oxazolidinones
- preparing oxazolidinones
- Prior art date
Links
- IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical class O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Vascular Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Se describen métodos para preparar una clase de oxazolidinonas útiles para impedir el crecimiento bacteriano.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10446908P | 2008-10-10 | 2008-10-10 | |
PCT/US2009/060267 WO2010042887A2 (en) | 2008-10-10 | 2009-10-09 | Methods for preparing oxazolidinones and compositions containing them |
Publications (1)
Publication Number | Publication Date |
---|---|
MX366793B true MX366793B (es) | 2019-07-24 |
Family
ID=41382395
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2011003820A MX2011003820A (es) | 2008-10-10 | 2009-10-09 | Metodos para preparar oxazolidinonas y composiciones que las contienen. |
MX2014004600A MX366793B (es) | 2008-10-10 | 2009-10-09 | Metodos para preparar oxazolidinonas y composiciones que las contienen. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2011003820A MX2011003820A (es) | 2008-10-10 | 2009-10-09 | Metodos para preparar oxazolidinonas y composiciones que las contienen. |
Country Status (13)
Country | Link |
---|---|
US (2) | US8604209B2 (es) |
EP (2) | EP2346858B1 (es) |
JP (1) | JP5773875B2 (es) |
KR (1) | KR101674146B1 (es) |
CN (2) | CN106220621B (es) |
AU (1) | AU2009303301B2 (es) |
CA (1) | CA2738671C (es) |
ES (2) | ES2744907T3 (es) |
HK (2) | HK1200169A1 (es) |
MX (2) | MX2011003820A (es) |
RU (2) | RU2659792C1 (es) |
SG (2) | SG195544A1 (es) |
WO (1) | WO2010042887A2 (es) |
Families Citing this family (45)
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KR100854211B1 (ko) * | 2003-12-18 | 2008-08-26 | 동아제약주식회사 | 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물 |
KR101674146B1 (ko) * | 2008-10-10 | 2016-11-08 | 머크 샤프 앤드 돔 코포레이션 | 옥사졸리디논 및 이를 포함하는 조성물을 제조하는 방법 |
CA2751392C (en) | 2009-02-03 | 2017-03-28 | Trius Therapeutics, Inc. | Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate |
US8580767B2 (en) * | 2009-05-28 | 2013-11-12 | Trius Therapeutics, Inc. | Oxazolidinone containing dimer compounds, compositions and methods to make and use |
WO2012033952A1 (en) | 2010-09-10 | 2012-03-15 | Micurx Pharmaceuticals, Inc. | 3 - phenyl- 2 -oxo- 1, 3 -oxazolidines for treatment of bacterial infections |
WO2016009401A2 (en) * | 2014-07-18 | 2016-01-21 | Dr. Reddy's Laboratories Limited | Preparation of tedizolid phosphate |
CN105367547B (zh) * | 2014-08-19 | 2019-04-23 | 北京桦冠生物技术有限公司 | 一种噁唑啉酮抗生素的新合成工艺 |
CN104496979A (zh) * | 2014-09-17 | 2015-04-08 | 博瑞生物医药技术(苏州)有限公司 | 一种噁唑烷酮类化合物及其中间体的制备方法 |
WO2016041505A1 (zh) * | 2014-09-17 | 2016-03-24 | 正大天晴药业集团股份有限公司 | 一种磷酸特地唑胺、其中间体以及它们的制备方法 |
CN104327119A (zh) * | 2014-10-17 | 2015-02-04 | 苏州明锐医药科技有限公司 | 磷酸泰地唑胺的制备方法 |
WO2016088102A1 (en) * | 2014-12-05 | 2016-06-09 | Sun Pharmaceutical Industries Limited | Processes for the preparation of tedizolid phosphate and its intermediates |
WO2016088101A1 (en) * | 2014-12-05 | 2016-06-09 | Sun Pharmaceutical Industries Limited | Processes for the preparation of tedizolid phosphate and its intermediates |
WO2016088100A1 (en) * | 2014-12-05 | 2016-06-09 | Sun Pharmaceutical Industries Limited | Processes for the preparation of tedizolid phosphate and its intermediates |
WO2016088103A1 (en) * | 2014-12-05 | 2016-06-09 | Sun Pharmaceutical Industries Limited | A process for the preparation of tedizolid phosphate |
CN104558034A (zh) * | 2015-01-21 | 2015-04-29 | 齐鲁制药有限公司 | 磷酸特地唑胺二钠盐的新晶型及其制备方法 |
CN105837634B (zh) * | 2015-01-30 | 2020-09-04 | 上海创诺制药有限公司 | 一种泰地唑胺磷酸酯结晶体及其制备方法 |
CN104592218B (zh) * | 2015-02-13 | 2015-11-04 | 江苏欧信医药化工有限公司 | 一种泰地唑胺的合成方法 |
CN104892592A (zh) * | 2015-03-30 | 2015-09-09 | 成都惟新医药科技有限公司 | 一种泰地唑胺的制备方法 |
CN106146485B (zh) * | 2015-04-01 | 2021-04-30 | 上海迪赛诺化学制药有限公司 | 一种制备泰地唑胺的方法及其得到的泰地唑胺结晶体 |
CN106279281B (zh) * | 2015-05-15 | 2018-08-03 | 重庆圣华曦药业股份有限公司 | 噁唑烷酮类抗菌素泰地唑胺磷酸酯的精制方法 |
CN106279282B (zh) * | 2015-05-21 | 2019-08-23 | 博瑞生物医药(苏州)股份有限公司 | 一种磷酸特地唑胺的纯化方法 |
CN106317114B (zh) * | 2015-07-02 | 2018-11-20 | 南京优科制药有限公司 | 一种磷酸特地唑胺的制备方法 |
CN105131037B (zh) * | 2015-07-28 | 2017-05-03 | 济南爱思医药科技有限公司 | 一种高纯度泰地唑胺磷酸酯的制备方法 |
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KR101855334B1 (ko) * | 2015-12-11 | 2018-06-08 | 에스티팜 주식회사 | 옥사졸리디논 유도체의 중간체 제조방법 |
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CN106146560B (zh) * | 2016-07-12 | 2019-02-01 | 扬子江药业集团有限公司 | 一种高纯度磷酸特地唑胺的精制方法 |
CN106432182B (zh) * | 2016-09-06 | 2019-04-30 | 铜仁学院 | 特地唑胺中间体的合成方法 |
CN106565680A (zh) * | 2016-10-31 | 2017-04-19 | 瑞阳制药有限公司 | 特地唑胺杂质及其制备方法 |
CN108059624A (zh) * | 2016-11-08 | 2018-05-22 | 上海医药工业研究院 | 用于制备咔哒唑胺关键中间体的制备方法 |
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CN106699730A (zh) * | 2016-12-23 | 2017-05-24 | 山东轩德医药科技有限公司 | 2‑甲基‑5‑(5‑溴吡啶‑2‑基)四氮唑的制备方法 |
CN107722056A (zh) * | 2017-10-31 | 2018-02-23 | 重庆华邦胜凯制药有限公司 | 磷酸特地唑胺的制备方法 |
WO2019118311A1 (en) | 2017-12-13 | 2019-06-20 | Merck Sharp & Dohme Corp. | Pharmaceutical compositions of tedizolid phosphate |
CN110804038B (zh) * | 2018-08-06 | 2021-03-05 | 上海博志研新药物技术有限公司 | 磷酸特地唑胺及其中间体的制备方法 |
CN110938058B (zh) * | 2018-09-22 | 2022-04-12 | 南京优科生物医药研究有限公司 | 一种噁唑烷酮类抗生素中间体的制备方法 |
CN111116652A (zh) * | 2019-12-06 | 2020-05-08 | 山东中医药大学 | 一种高纯度磷酸特地唑胺的制备方法 |
CN113121518B (zh) * | 2019-12-31 | 2022-06-28 | 北京福元医药股份有限公司 | 一种特地唑胺杂质的制备方法 |
CN111285848A (zh) * | 2020-04-10 | 2020-06-16 | 苏州敬业医药化工有限公司 | 一种5-溴-2-(2-甲基-2h-四唑-5-基)吡啶的纯化方法 |
KR20230052873A (ko) | 2020-06-18 | 2023-04-20 | 아카제라 메디신즈, 인크. | 옥사졸리디논 화합물, 옥사졸리디논 화합물을 포함하는 리포좀 조성물 및 이의 사용 방법 |
CN114105946A (zh) * | 2020-08-26 | 2022-03-01 | 浙江苏泊尔制药有限公司 | 一种磷酸特地唑胺中间体及其制备方法 |
CN112961186A (zh) * | 2021-02-04 | 2021-06-15 | 海南通用康力制药有限公司 | 一种磷酸特地唑胺的纯化方法 |
CN113488445A (zh) * | 2021-07-05 | 2021-10-08 | 合肥巨一动力系统有限公司 | 一种igbt封装散热结构及其应用的电机控制器 |
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- 2009-10-09 JP JP2011531233A patent/JP5773875B2/ja active Active
- 2009-10-09 RU RU2015122033A patent/RU2659792C1/ru active
- 2009-10-09 EP EP09749235.9A patent/EP2346858B1/en active Active
- 2009-10-09 MX MX2011003820A patent/MX2011003820A/es active IP Right Grant
- 2009-10-09 ES ES14159112T patent/ES2744907T3/es active Active
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Also Published As
Publication number | Publication date |
---|---|
MX2011003820A (es) | 2011-06-16 |
KR101674146B1 (ko) | 2016-11-08 |
CA2738671A1 (en) | 2010-05-15 |
RU2011115109A (ru) | 2012-11-20 |
CN106220621B (zh) | 2019-06-11 |
AU2009303301A1 (en) | 2010-04-15 |
WO2010042887A3 (en) | 2010-06-24 |
US20100093669A1 (en) | 2010-04-15 |
HK1232221A1 (zh) | 2018-01-05 |
RU2659792C1 (ru) | 2018-07-04 |
US9328087B2 (en) | 2016-05-03 |
RU2556234C2 (ru) | 2015-07-10 |
US8604209B2 (en) | 2013-12-10 |
EP2346858A2 (en) | 2011-07-27 |
SG195544A1 (en) | 2013-12-30 |
CN102177156B (zh) | 2016-08-24 |
AU2009303301B2 (en) | 2014-09-11 |
ES2748505T3 (es) | 2020-03-17 |
EP2346858B1 (en) | 2019-08-07 |
US20140206878A1 (en) | 2014-07-24 |
KR20110071107A (ko) | 2011-06-28 |
HK1200169A1 (en) | 2015-07-31 |
JP2012505252A (ja) | 2012-03-01 |
EP2757104A1 (en) | 2014-07-23 |
CN106220621A (zh) | 2016-12-14 |
WO2010042887A2 (en) | 2010-04-15 |
CA2738671C (en) | 2018-05-01 |
CN102177156A (zh) | 2011-09-07 |
ES2744907T3 (es) | 2020-02-26 |
JP5773875B2 (ja) | 2015-09-02 |
SG10201702946RA (en) | 2017-05-30 |
EP2757104B1 (en) | 2019-08-14 |
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