MX361128B - Agente terapéutico o agente profiláctico para los trastornos cognitivos. - Google Patents

Agente terapéutico o agente profiláctico para los trastornos cognitivos.

Info

Publication number
MX361128B
MX361128B MX2014014187A MX2014014187A MX361128B MX 361128 B MX361128 B MX 361128B MX 2014014187 A MX2014014187 A MX 2014014187A MX 2014014187 A MX2014014187 A MX 2014014187A MX 361128 B MX361128 B MX 361128B
Authority
MX
Mexico
Prior art keywords
agent
dementia
therapeutic agent
prophylactic
prophylactic agent
Prior art date
Application number
MX2014014187A
Other languages
English (en)
Spanish (es)
Other versions
MX2014014187A (es
Inventor
Mori Hiroshi
Tomiyama Takami
Matsumoto Yoichi
Eguchi Hiroshi
Kunori Yuichi
Original Assignee
Univ Osaka City
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Osaka City filed Critical Univ Osaka City
Publication of MX2014014187A publication Critical patent/MX2014014187A/es
Publication of MX361128B publication Critical patent/MX361128B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
MX2014014187A 2012-05-31 2013-05-30 Agente terapéutico o agente profiláctico para los trastornos cognitivos. MX361128B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012124336 2012-05-31
PCT/JP2013/065090 WO2013180238A1 (ja) 2012-05-31 2013-05-30 認知症治療剤又は予防剤

Publications (2)

Publication Number Publication Date
MX2014014187A MX2014014187A (es) 2015-06-04
MX361128B true MX361128B (es) 2018-11-28

Family

ID=49673425

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014014187A MX361128B (es) 2012-05-31 2013-05-30 Agente terapéutico o agente profiláctico para los trastornos cognitivos.

Country Status (30)

Country Link
US (3) US20150183854A1 (enExample)
EP (2) EP2857039B1 (enExample)
JP (3) JP5971659B2 (enExample)
KR (2) KR102133610B1 (enExample)
CN (1) CN104602708B (enExample)
AR (1) AR091218A1 (enExample)
AU (2) AU2013268364B2 (enExample)
BR (1) BR112014029566A2 (enExample)
CA (1) CA2875205C (enExample)
CY (1) CY1122530T1 (enExample)
DK (1) DK2857039T3 (enExample)
ES (2) ES2763361T3 (enExample)
HR (1) HRP20192267T1 (enExample)
HU (1) HUE046919T2 (enExample)
IL (1) IL235899B (enExample)
LT (1) LT2857039T (enExample)
ME (1) ME03587B (enExample)
MX (1) MX361128B (enExample)
MY (1) MY172458A (enExample)
NZ (1) NZ630536A (enExample)
PH (1) PH12014502669B1 (enExample)
PL (1) PL2857039T3 (enExample)
PT (1) PT2857039T (enExample)
RS (1) RS59802B1 (enExample)
RU (1) RU2657438C2 (enExample)
SG (2) SG10201805410XA (enExample)
SI (1) SI2857039T1 (enExample)
TW (2) TWI700296B (enExample)
WO (1) WO2013180238A1 (enExample)
ZA (1) ZA201409186B (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8703137B2 (en) 2011-01-31 2014-04-22 Intellect Neurosciences Inc. Treatment of tauopathies
EP2709728B1 (en) * 2011-05-20 2019-01-23 Oligomerix, Inc. Tau protease methods of use
BR112014029566A2 (pt) * 2012-05-31 2017-07-25 Univ Osaka City agente terapêutico ou agente profilático para desordens cognitivas, anticorpo monoclonal, anticorpo para proteína tau fosforilada, e, peptídeo
JP6345655B2 (ja) 2012-07-03 2018-06-20 ワシントン・ユニバーシティWashington University タウに対する抗体
TW202136296A (zh) * 2014-06-27 2021-10-01 美商C2N醫療診斷有限責任公司 人類化抗-tau抗體
US20190224339A1 (en) * 2016-04-29 2019-07-25 Voyager Therapeutics, Inc. Compositions for the treatment of disease
CN109791149A (zh) * 2016-09-30 2019-05-21 豪夫迈·罗氏有限公司 用于功能分析多特异性分子的基于spr的双重结合测定法
SG11201907422RA (en) 2017-02-17 2019-09-27 Denali Therapeutics Inc Anti-tau antibodies and methods of use thereof
JP2018139530A (ja) 2017-02-27 2018-09-13 帝人ファーマ株式会社 認知症治療又は予防のためのヒト化抗体及びその製造方法、並びにそれを用いた認知症治療剤又は予防剤
BR112019022789A2 (pt) 2017-05-30 2020-06-09 Teijin Pharma Ltd anticorpo do receptor de anti-igf-i ou fragmento do mesmo ou um derivado do mesmo, molécula de ácido nucleico, vetor de clonagem ou vetor de expressão, célula recombinante, processo de produção de um anticorpo do receptor de anti-igf-i ou fragmento do mesmo ou um derivado do mesmo, composição farmacêutica, medicamento, método para cultivar células derivadas de vertebrados in vitro, e, animal transgênico.
MA50629A (fr) 2017-10-02 2021-03-31 Merck Sharp & Dohme Composés monobactames de chromane pour le traitement d'infections bactériennes
NZ762251A (en) 2017-10-16 2025-12-19 Eisai R&D Man Co Ltd Anti-tau antibodies and uses thereof
US11667707B2 (en) 2018-04-06 2023-06-06 Teijin Pharma Limited SPNS2 neutralizing antibody
CN112469827B (zh) * 2018-07-04 2024-05-24 学校法人爱知医科大学 控制Tau的剪接的反义寡核苷酸及其用途
CN110028583B (zh) * 2019-05-07 2020-09-11 温州医科大学 抗Tau抗体及其在治疗阿尔茨海默病、创伤性脑损伤中的应用
GB2585252A (en) 2019-07-05 2021-01-06 Gen2 Neuroscience Ltd Tau epitope and binding molecules
JP7429404B2 (ja) * 2019-08-06 2024-02-08 慶應義塾 タウ関連疾患モデルの製造方法
EP4040153A4 (en) 2019-09-30 2023-07-26 Nipro Corporation PROCEDURE FOR DETECTING TAU PROTEIN USING A BLOOD SAMPLE AS SAMPLE
JP2023518281A (ja) 2020-03-19 2023-04-28 ヴァスキュラー バイオサイエンスィズ コロナウイルス生存率改善のためのcarペプチド
EP4171633A1 (en) * 2020-06-25 2023-05-03 Merck Sharp & Dohme LLC High affinity antibodies targeting tau phosphorylated at serine 413
US20250034559A1 (en) 2021-11-17 2025-01-30 Voyager Therapeutics, Inc. Compositions and methods for the treatment of tau-related disorders
CN120019071A (zh) 2022-09-15 2025-05-16 沃雅戈治疗公司 Tau结合化合物
WO2025122634A1 (en) 2023-12-05 2025-06-12 Voyager Therapeutics, Inc. Compositions and methods for the treatment of tau-related disorders

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS587390B2 (ja) 1975-03-11 1983-02-09 ツキシマキカイ カブシキガイシヤ ア−クヨウセツホウホウ
JP3587390B2 (ja) 1994-03-17 2004-11-10 タカラバイオ株式会社 リン酸化アミノ酸誘導体及びリン酸化ペプチド合成方法
US20020086009A1 (en) * 1996-03-13 2002-07-04 Koichi Ishiguro Anti-phosphorylated tau protein antibodies and methods for detecting alzheimer`s disease with the use of the same
US20080199471A1 (en) * 2002-03-01 2008-08-21 Bernett Matthew J Optimized cd40 antibodies and methods of using the same
US8012936B2 (en) 2006-03-29 2011-09-06 New York University Tau fragments for immunotherapy
US20070280935A1 (en) * 2006-04-07 2007-12-06 Bernd Bohrmann Antibody that recognizes phosphorylated peptides
CA2655634A1 (en) * 2006-06-16 2007-12-27 Envivo Pharmaceuticals, Inc. Transgenic flies expressing tau and amyloid precursor fragment
UA107571C2 (xx) * 2009-04-03 2015-01-26 Фармацевтична композиція
CA3239368A1 (en) 2009-06-10 2010-12-16 New York University Immunological targeting of pathological tau proteins
US8609097B2 (en) 2009-06-10 2013-12-17 Hoffmann-La Roche Inc. Use of an anti-Tau pS422 antibody for the treatment of brain diseases
US8703137B2 (en) * 2011-01-31 2014-04-22 Intellect Neurosciences Inc. Treatment of tauopathies
TR201102696U (tr) * 2011-05-27 2011-06-21 Turhal Sal�H Bağlantısız hareketli ürün reklam standı.
BR112014029566A2 (pt) * 2012-05-31 2017-07-25 Univ Osaka City agente terapêutico ou agente profilático para desordens cognitivas, anticorpo monoclonal, anticorpo para proteína tau fosforilada, e, peptídeo
JP2018139530A (ja) * 2017-02-27 2018-09-13 帝人ファーマ株式会社 認知症治療又は予防のためのヒト化抗体及びその製造方法、並びにそれを用いた認知症治療剤又は予防剤

Also Published As

Publication number Publication date
AU2018200413A1 (en) 2018-02-08
AU2013268364B2 (en) 2018-02-08
ES2973070T3 (es) 2024-06-18
JP6620829B2 (ja) 2019-12-18
TW201410705A (zh) 2014-03-16
HUE046919T2 (hu) 2020-04-28
SG10201805410XA (en) 2018-08-30
SI2857039T1 (sl) 2020-03-31
EP3662931A1 (en) 2020-06-10
WO2013180238A1 (ja) 2013-12-05
RU2014153099A (ru) 2016-07-20
EP2857039A4 (en) 2015-08-26
US20200148753A1 (en) 2020-05-14
TWI777183B (zh) 2022-09-11
HRP20192267T1 (hr) 2020-03-20
EP2857039A1 (en) 2015-04-08
MX2014014187A (es) 2015-06-04
RS59802B1 (sr) 2020-02-28
IL235899B (en) 2019-03-31
KR102208283B1 (ko) 2021-01-26
KR20200029619A (ko) 2020-03-18
CY1122530T1 (el) 2021-01-27
DK2857039T3 (da) 2019-12-16
JPWO2013180238A1 (ja) 2016-01-21
LT2857039T (lt) 2020-03-10
ZA201409186B (en) 2015-12-23
TWI700296B (zh) 2020-08-01
AU2013268364A1 (en) 2014-12-18
PT2857039T (pt) 2020-01-07
AU2018200413B2 (en) 2019-10-17
CA2875205C (en) 2021-07-20
EP2857039B1 (en) 2019-11-20
TW202041532A (zh) 2020-11-16
HK1210031A1 (en) 2016-04-15
JP2016147902A (ja) 2016-08-18
JP5971659B2 (ja) 2016-08-17
KR20150027098A (ko) 2015-03-11
PH12014502669A1 (en) 2015-02-02
PH12014502669B1 (en) 2020-02-19
RU2657438C2 (ru) 2018-06-13
CA2875205A1 (en) 2013-12-05
CN104602708B (zh) 2021-11-30
JP2018111716A (ja) 2018-07-19
SG11201407878VA (en) 2015-01-29
IL235899A0 (en) 2015-01-29
AR091218A1 (es) 2015-01-21
BR112014029566A2 (pt) 2017-07-25
CN104602708A (zh) 2015-05-06
US20150183854A1 (en) 2015-07-02
KR102133610B1 (ko) 2020-07-14
JP6406678B2 (ja) 2018-10-17
ME03587B (me) 2020-07-20
US20220340646A1 (en) 2022-10-27
MY172458A (en) 2019-11-26
ES2763361T3 (es) 2020-05-28
NZ630536A (en) 2017-03-31
EP3662931B1 (en) 2023-12-06
PL2857039T3 (pl) 2020-05-18

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