LT2857039T - Terapinis agentas arba profilaktinis agentas nuo demencijos - Google Patents

Terapinis agentas arba profilaktinis agentas nuo demencijos

Info

Publication number
LT2857039T
LT2857039T LTEP13797290.7T LT13797290T LT2857039T LT 2857039 T LT2857039 T LT 2857039T LT 13797290 T LT13797290 T LT 13797290T LT 2857039 T LT2857039 T LT 2857039T
Authority
LT
Lithuania
Prior art keywords
agent
dementia
prophylactic
therapeutic agent
therapeutic
Prior art date
Application number
LTEP13797290.7T
Other languages
English (en)
Lithuanian (lt)
Inventor
Hiroshi Mori
Takami Tomiyama
Yoichi Matsumoto
Hiroshi Eguchi
Yuichi Kunori
Original Assignee
Osaka City University
Teijin Pharma Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osaka City University, Teijin Pharma Limited filed Critical Osaka City University
Publication of LT2857039T publication Critical patent/LT2857039T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
LTEP13797290.7T 2012-05-31 2013-05-30 Terapinis agentas arba profilaktinis agentas nuo demencijos LT2857039T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012124336 2012-05-31
PCT/JP2013/065090 WO2013180238A1 (ja) 2012-05-31 2013-05-30 認知症治療剤又は予防剤

Publications (1)

Publication Number Publication Date
LT2857039T true LT2857039T (lt) 2020-03-10

Family

ID=49673425

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP13797290.7T LT2857039T (lt) 2012-05-31 2013-05-30 Terapinis agentas arba profilaktinis agentas nuo demencijos

Country Status (30)

Country Link
US (3) US20150183854A1 (enExample)
EP (2) EP3662931B1 (enExample)
JP (3) JP5971659B2 (enExample)
KR (2) KR102133610B1 (enExample)
CN (1) CN104602708B (enExample)
AR (1) AR091218A1 (enExample)
AU (2) AU2013268364B2 (enExample)
BR (1) BR112014029566A2 (enExample)
CA (1) CA2875205C (enExample)
CY (1) CY1122530T1 (enExample)
DK (1) DK2857039T3 (enExample)
ES (2) ES2763361T3 (enExample)
HR (1) HRP20192267T1 (enExample)
HU (1) HUE046919T2 (enExample)
IL (1) IL235899B (enExample)
LT (1) LT2857039T (enExample)
ME (1) ME03587B (enExample)
MX (1) MX361128B (enExample)
MY (1) MY172458A (enExample)
NZ (1) NZ630536A (enExample)
PH (1) PH12014502669B1 (enExample)
PL (1) PL2857039T3 (enExample)
PT (1) PT2857039T (enExample)
RS (1) RS59802B1 (enExample)
RU (1) RU2657438C2 (enExample)
SG (2) SG11201407878VA (enExample)
SI (1) SI2857039T1 (enExample)
TW (2) TWI777183B (enExample)
WO (1) WO2013180238A1 (enExample)
ZA (1) ZA201409186B (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2670434B1 (en) 2011-01-31 2018-12-26 Tau Bio-Logic Corp. Treatment of tauopathies
US9506051B2 (en) * 2011-05-20 2016-11-29 Oligomerix, Inc. Tau protease compositions and methods of use
RU2657438C2 (ru) * 2012-05-31 2018-06-13 Осака Сити Юниверсити Терапевтическое средство или профилактическое средство против деменции
KR20200013072A (ko) 2012-07-03 2020-02-05 워싱턴 유니버시티 Tau에 대한 항체
TW202136296A (zh) 2014-06-27 2021-10-01 美商C2N醫療診斷有限責任公司 人類化抗-tau抗體
EP3448875A4 (en) * 2016-04-29 2020-04-08 Voyager Therapeutics, Inc. Compositions for the treatment of disease
WO2018060035A1 (en) * 2016-09-30 2018-04-05 F. Hoffmann-La Roche Ag Spr-based dual-binding assay for the functional analysis of multispecific molecules
CN110520440A (zh) 2017-02-17 2019-11-29 戴纳立制药公司 抗τ抗体及其使用方法
JP2018139530A (ja) * 2017-02-27 2018-09-13 帝人ファーマ株式会社 認知症治療又は予防のためのヒト化抗体及びその製造方法、並びにそれを用いた認知症治療剤又は予防剤
MX2019014174A (es) 2017-05-30 2020-01-27 Teijin Pharma Ltd Anticuerpo anti-receptor de igf-i.
MX2020003581A (es) 2017-10-02 2020-07-22 Merck Sharp & Dohme Compuestos monobactamicos cromanos para el tratamiento de infecciones bacterianas.
TWI853617B (zh) 2017-10-16 2024-08-21 日商衛材R&D企管股份有限公司 抗tau抗體及其用途
EP3778631A4 (en) 2018-04-06 2022-01-05 Teijin Pharma Limited Spns2 neutralizing antibody
EP3819378A4 (en) * 2018-07-04 2022-09-14 Aichi Medical University OLIGONUCLEOTIDES FOR CONTROL OF TAU SPLICING AND THEIR USES
CN110028583B (zh) * 2019-05-07 2020-09-11 温州医科大学 抗Tau抗体及其在治疗阿尔茨海默病、创伤性脑损伤中的应用
JP7429404B2 (ja) * 2019-08-06 2024-02-08 慶應義塾 タウ関連疾患モデルの製造方法
WO2021065306A1 (ja) 2019-09-30 2021-04-08 ニプロ株式会社 血液試料を検体とするタウタンパク質検出方法
US20230137434A1 (en) * 2020-03-19 2023-05-04 Vascular Biosciences CAR Peptide for Improved Coronavirus Survival
CN116723856A (zh) * 2020-06-25 2023-09-08 默沙东有限责任公司 靶向丝氨酸413处磷酸化的tau的高亲和力抗体
WO2023092004A1 (en) 2021-11-17 2023-05-25 Voyager Therapeutics, Inc. Compositions and methods for the treatment of tau-related disorders
JP2025535203A (ja) 2022-09-15 2025-10-23 ボイジャー セラピューティクス インコーポレイテッド タウ結合化合物
WO2025122634A1 (en) 2023-12-05 2025-06-12 Voyager Therapeutics, Inc. Compositions and methods for the treatment of tau-related disorders

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS587390B2 (ja) 1975-03-11 1983-02-09 ツキシマキカイ カブシキガイシヤ ア−クヨウセツホウホウ
JP3587390B2 (ja) 1994-03-17 2004-11-10 タカラバイオ株式会社 リン酸化アミノ酸誘導体及びリン酸化ペプチド合成方法
WO1997034145A1 (fr) 1996-03-13 1997-09-18 Mitsubishi Chemical Corporation Anticorps a proteine tau antiphosphorylee et procede de detection de la maladie d'alzheimer l'utilisant
US20080199471A1 (en) * 2002-03-01 2008-08-21 Bernett Matthew J Optimized cd40 antibodies and methods of using the same
US8012936B2 (en) 2006-03-29 2011-09-06 New York University Tau fragments for immunotherapy
US20070280935A1 (en) * 2006-04-07 2007-12-06 Bernd Bohrmann Antibody that recognizes phosphorylated peptides
EP2028932A4 (en) * 2006-06-16 2011-10-12 Vitruvean Llc TAU AND AMYLOID FOREIGNER FRAGMENT EXPRESSING TRANSGENIC FLY
UA107571C2 (xx) * 2009-04-03 2015-01-26 Фармацевтична композиція
JP5917394B2 (ja) * 2009-06-10 2016-05-11 ニューヨーク・ユニバーシティ 病理学的タウタンパク質の免疫学的標的化方法
US8609097B2 (en) 2009-06-10 2013-12-17 Hoffmann-La Roche Inc. Use of an anti-Tau pS422 antibody for the treatment of brain diseases
EP2670434B1 (en) * 2011-01-31 2018-12-26 Tau Bio-Logic Corp. Treatment of tauopathies
TR201102696U (tr) * 2011-05-27 2011-06-21 Turhal Sal�H Bağlantısız hareketli ürün reklam standı.
RU2657438C2 (ru) * 2012-05-31 2018-06-13 Осака Сити Юниверсити Терапевтическое средство или профилактическое средство против деменции
JP2018139530A (ja) * 2017-02-27 2018-09-13 帝人ファーマ株式会社 認知症治療又は予防のためのヒト化抗体及びその製造方法、並びにそれを用いた認知症治療剤又は予防剤

Also Published As

Publication number Publication date
US20150183854A1 (en) 2015-07-02
PT2857039T (pt) 2020-01-07
SG11201407878VA (en) 2015-01-29
ES2973070T3 (es) 2024-06-18
KR102133610B1 (ko) 2020-07-14
TW201410705A (zh) 2014-03-16
JPWO2013180238A1 (ja) 2016-01-21
PL2857039T3 (pl) 2020-05-18
PH12014502669B1 (en) 2020-02-19
SI2857039T1 (sl) 2020-03-31
CN104602708B (zh) 2021-11-30
MX2014014187A (es) 2015-06-04
RS59802B1 (sr) 2020-02-28
IL235899B (en) 2019-03-31
RU2014153099A (ru) 2016-07-20
MY172458A (en) 2019-11-26
DK2857039T3 (da) 2019-12-16
HK1210031A1 (en) 2016-04-15
KR20150027098A (ko) 2015-03-11
CN104602708A (zh) 2015-05-06
HRP20192267T1 (hr) 2020-03-20
NZ630536A (en) 2017-03-31
US20200148753A1 (en) 2020-05-14
EP2857039B1 (en) 2019-11-20
WO2013180238A1 (ja) 2013-12-05
CA2875205A1 (en) 2013-12-05
CY1122530T1 (el) 2021-01-27
JP6620829B2 (ja) 2019-12-18
ME03587B (me) 2020-07-20
AU2013268364B2 (en) 2018-02-08
EP2857039A4 (en) 2015-08-26
IL235899A0 (en) 2015-01-29
CA2875205C (en) 2021-07-20
EP2857039A1 (en) 2015-04-08
JP2018111716A (ja) 2018-07-19
AR091218A1 (es) 2015-01-21
KR20200029619A (ko) 2020-03-18
SG10201805410XA (en) 2018-08-30
AU2018200413B2 (en) 2019-10-17
TWI777183B (zh) 2022-09-11
AU2013268364A1 (en) 2014-12-18
JP6406678B2 (ja) 2018-10-17
JP5971659B2 (ja) 2016-08-17
MX361128B (es) 2018-11-28
EP3662931A1 (en) 2020-06-10
PH12014502669A1 (en) 2015-02-02
EP3662931B1 (en) 2023-12-06
JP2016147902A (ja) 2016-08-18
TW202041532A (zh) 2020-11-16
AU2018200413A1 (en) 2018-02-08
RU2657438C2 (ru) 2018-06-13
KR102208283B1 (ko) 2021-01-26
BR112014029566A2 (pt) 2017-07-25
US20220340646A1 (en) 2022-10-27
TWI700296B (zh) 2020-08-01
ES2763361T3 (es) 2020-05-28
ZA201409186B (en) 2015-12-23
HUE046919T2 (hu) 2020-04-28

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