AU2013268364B2 - Therapeutic agent or prophylactic agent for dementia - Google Patents

Therapeutic agent or prophylactic agent for dementia Download PDF

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Publication number
AU2013268364B2
AU2013268364B2 AU2013268364A AU2013268364A AU2013268364B2 AU 2013268364 B2 AU2013268364 B2 AU 2013268364B2 AU 2013268364 A AU2013268364 A AU 2013268364A AU 2013268364 A AU2013268364 A AU 2013268364A AU 2013268364 B2 AU2013268364 B2 AU 2013268364B2
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AU
Australia
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gly
lys
pro
thr
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AU2013268364A
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English (en)
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AU2013268364A1 (en
Inventor
Hiroshi Eguchi
Yuichi Kunori
Yoichi Matsumoto
Hiroshi Mori
Takami Tomiyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Osaka Metropolitan University
Original Assignee
Osaka University NUC
Osaka City University PUC
Teijin Ltd
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Publication date
Application filed by Osaka University NUC, Osaka City University PUC, Teijin Ltd filed Critical Osaka University NUC
Publication of AU2013268364A1 publication Critical patent/AU2013268364A1/en
Priority to AU2018200413A priority Critical patent/AU2018200413B2/en
Application granted granted Critical
Publication of AU2013268364B2 publication Critical patent/AU2013268364B2/en
Assigned to TEIJIN LIMITED, OSAKA CITY UNIVERSITY reassignment TEIJIN LIMITED Request for Assignment Assignors: OSAKA CITY UNIVERSITY, TEIJIN PHARMA LIMITED
Active legal-status Critical Current
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2013268364A 2012-05-31 2013-05-30 Therapeutic agent or prophylactic agent for dementia Active AU2013268364B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2018200413A AU2018200413B2 (en) 2012-05-31 2018-01-18 Therapeutic agent or prophylactic agent for dementia

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012124336 2012-05-31
JP2012-124336 2012-05-31
PCT/JP2013/065090 WO2013180238A1 (ja) 2012-05-31 2013-05-30 認知症治療剤又は予防剤

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2018200413A Division AU2018200413B2 (en) 2012-05-31 2018-01-18 Therapeutic agent or prophylactic agent for dementia

Publications (2)

Publication Number Publication Date
AU2013268364A1 AU2013268364A1 (en) 2014-12-18
AU2013268364B2 true AU2013268364B2 (en) 2018-02-08

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
AU2013268364A Active AU2013268364B2 (en) 2012-05-31 2013-05-30 Therapeutic agent or prophylactic agent for dementia
AU2018200413A Active AU2018200413B2 (en) 2012-05-31 2018-01-18 Therapeutic agent or prophylactic agent for dementia

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2018200413A Active AU2018200413B2 (en) 2012-05-31 2018-01-18 Therapeutic agent or prophylactic agent for dementia

Country Status (30)

Country Link
US (3) US20150183854A1 (enExample)
EP (2) EP2857039B1 (enExample)
JP (3) JP5971659B2 (enExample)
KR (2) KR102208283B1 (enExample)
CN (1) CN104602708B (enExample)
AR (1) AR091218A1 (enExample)
AU (2) AU2013268364B2 (enExample)
BR (1) BR112014029566A2 (enExample)
CA (1) CA2875205C (enExample)
CY (1) CY1122530T1 (enExample)
DK (1) DK2857039T3 (enExample)
ES (2) ES2973070T3 (enExample)
HR (1) HRP20192267T1 (enExample)
HU (1) HUE046919T2 (enExample)
IL (1) IL235899B (enExample)
LT (1) LT2857039T (enExample)
ME (1) ME03587B (enExample)
MX (1) MX361128B (enExample)
MY (1) MY172458A (enExample)
NZ (1) NZ630536A (enExample)
PH (1) PH12014502669B1 (enExample)
PL (1) PL2857039T3 (enExample)
PT (1) PT2857039T (enExample)
RS (1) RS59802B1 (enExample)
RU (1) RU2657438C2 (enExample)
SG (2) SG11201407878VA (enExample)
SI (1) SI2857039T1 (enExample)
TW (2) TWI777183B (enExample)
WO (1) WO2013180238A1 (enExample)
ZA (1) ZA201409186B (enExample)

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CA2826286C (en) 2011-01-31 2021-09-21 Intellect Neurosciences Inc. Treatment of tauopathies
EP2709728B1 (en) * 2011-05-20 2019-01-23 Oligomerix, Inc. Tau protease methods of use
MY172458A (en) * 2012-05-31 2019-11-26 Teijin Pharma Ltd Therapeutic agent or prophylactic agent for dementia
MY171473A (en) 2012-07-03 2019-10-15 Univ Washington Antibodies to tau
TW202136296A (zh) 2014-06-27 2021-10-01 美商C2N醫療診斷有限責任公司 人類化抗-tau抗體
US20190224339A1 (en) * 2016-04-29 2019-07-25 Voyager Therapeutics, Inc. Compositions for the treatment of disease
JP6785372B2 (ja) * 2016-09-30 2020-11-18 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 多重特異性分子の機能分析のためのsprに基づく二重結合アッセイ
MA47499A (fr) 2017-02-17 2019-12-25 Denali Therapeutics Inc Anticorps anti-tau et leurs procédés d'utilisation
JOP20180014A1 (ar) * 2017-02-27 2019-01-30 Teijin Pharma Ltd جسم مضاد متوافق مع البشر لعلاج أو الوقاية من الاضطرابات الإدراكية، وعملية لإنتاجه، وعامل لعلاج أو الوقاية من الاضطرابات الإدراكية باستخدامه
CN110691794B (zh) 2017-05-30 2023-10-27 帝人制药株式会社 抗igf-i受体抗体
GEP20227406B (en) 2017-10-02 2022-08-25 Merck Sharp & Dohme Chromane monobactam compounds for the treatment of bacterial infections
WO2019077500A1 (en) 2017-10-16 2019-04-25 Eisai R&D Management Co., Ltd. ANTI-WATER ANTIBODIES AND USES THEREOF
JP7504026B2 (ja) 2018-04-06 2024-06-21 帝人ファーマ株式会社 Spns2中和抗体
JP7340794B2 (ja) * 2018-07-04 2023-09-08 学校法人 愛知医科大学 タウのスプライシングを制御するアンチセンスオリゴヌクレオチド及びその用途
CN110028583B (zh) * 2019-05-07 2020-09-11 温州医科大学 抗Tau抗体及其在治疗阿尔茨海默病、创伤性脑损伤中的应用
JP7429404B2 (ja) * 2019-08-06 2024-02-08 慶應義塾 タウ関連疾患モデルの製造方法
JP7718270B2 (ja) 2019-09-30 2025-08-05 ニプロ株式会社 血液試料を検体とするタウタンパク質検出方法
EP4121071A4 (en) * 2020-03-19 2024-07-24 Vascular Biosciences PEPTIDE CAR FOR IMPROVED CORONAVIRUS SURVIVAL
BR112022026575A2 (pt) 2020-06-25 2023-01-17 Merck Sharp & Dohme Llc Anticorpos de alta afinidade que alvejam tau fosforilado em serina 413
US20250034559A1 (en) 2021-11-17 2025-01-30 Voyager Therapeutics, Inc. Compositions and methods for the treatment of tau-related disorders
AU2023342086A1 (en) 2022-09-15 2025-03-13 Voyager Therapeutics, Inc. Tau binding compounds
WO2025122634A1 (en) 2023-12-05 2025-06-12 Voyager Therapeutics, Inc. Compositions and methods for the treatment of tau-related disorders

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WO2010144711A2 (en) * 2009-06-10 2010-12-16 New York University Immunological targeting of pathological tau proteins

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JPS587390B2 (ja) 1975-03-11 1983-02-09 ツキシマキカイ カブシキガイシヤ ア−クヨウセツホウホウ
JP3587390B2 (ja) 1994-03-17 2004-11-10 タカラバイオ株式会社 リン酸化アミノ酸誘導体及びリン酸化ペプチド合成方法
US20020086009A1 (en) * 1996-03-13 2002-07-04 Koichi Ishiguro Anti-phosphorylated tau protein antibodies and methods for detecting alzheimer`s disease with the use of the same
US20080199471A1 (en) * 2002-03-01 2008-08-21 Bernett Matthew J Optimized cd40 antibodies and methods of using the same
US8012936B2 (en) 2006-03-29 2011-09-06 New York University Tau fragments for immunotherapy
US20070280935A1 (en) * 2006-04-07 2007-12-06 Bernd Bohrmann Antibody that recognizes phosphorylated peptides
EP2028932A4 (en) * 2006-06-16 2011-10-12 Vitruvean Llc TAU AND AMYLOID FOREIGNER FRAGMENT EXPRESSING TRANSGENIC FLY
UA107571C2 (xx) * 2009-04-03 2015-01-26 Фармацевтична композиція
US8609097B2 (en) 2009-06-10 2013-12-17 Hoffmann-La Roche Inc. Use of an anti-Tau pS422 antibody for the treatment of brain diseases
CA2826286C (en) * 2011-01-31 2021-09-21 Intellect Neurosciences Inc. Treatment of tauopathies
TR201102696U (tr) * 2011-05-27 2011-06-21 Turhal Sal�H Bağlantısız hareketli ürün reklam standı.
MY172458A (en) * 2012-05-31 2019-11-26 Teijin Pharma Ltd Therapeutic agent or prophylactic agent for dementia
JOP20180014A1 (ar) * 2017-02-27 2019-01-30 Teijin Pharma Ltd جسم مضاد متوافق مع البشر لعلاج أو الوقاية من الاضطرابات الإدراكية، وعملية لإنتاجه، وعامل لعلاج أو الوقاية من الاضطرابات الإدراكية باستخدامه

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WO2010144711A2 (en) * 2009-06-10 2010-12-16 New York University Immunological targeting of pathological tau proteins

Also Published As

Publication number Publication date
JPWO2013180238A1 (ja) 2016-01-21
AR091218A1 (es) 2015-01-21
AU2018200413B2 (en) 2019-10-17
AU2013268364A1 (en) 2014-12-18
CN104602708A (zh) 2015-05-06
WO2013180238A1 (ja) 2013-12-05
JP6406678B2 (ja) 2018-10-17
HUE046919T2 (hu) 2020-04-28
LT2857039T (lt) 2020-03-10
TWI777183B (zh) 2022-09-11
US20220340646A1 (en) 2022-10-27
RU2014153099A (ru) 2016-07-20
MY172458A (en) 2019-11-26
RU2657438C2 (ru) 2018-06-13
HK1210031A1 (en) 2016-04-15
CY1122530T1 (el) 2021-01-27
EP2857039A4 (en) 2015-08-26
ES2763361T3 (es) 2020-05-28
PH12014502669B1 (en) 2020-02-19
MX361128B (es) 2018-11-28
NZ630536A (en) 2017-03-31
KR102133610B1 (ko) 2020-07-14
CA2875205C (en) 2021-07-20
SG11201407878VA (en) 2015-01-29
US20150183854A1 (en) 2015-07-02
EP3662931B1 (en) 2023-12-06
KR20150027098A (ko) 2015-03-11
TWI700296B (zh) 2020-08-01
PL2857039T3 (pl) 2020-05-18
AU2018200413A1 (en) 2018-02-08
PT2857039T (pt) 2020-01-07
KR102208283B1 (ko) 2021-01-26
US20200148753A1 (en) 2020-05-14
ZA201409186B (en) 2015-12-23
JP2018111716A (ja) 2018-07-19
CA2875205A1 (en) 2013-12-05
TW201410705A (zh) 2014-03-16
MX2014014187A (es) 2015-06-04
RS59802B1 (sr) 2020-02-28
EP2857039B1 (en) 2019-11-20
HRP20192267T1 (hr) 2020-03-20
BR112014029566A2 (pt) 2017-07-25
JP5971659B2 (ja) 2016-08-17
ME03587B (me) 2020-07-20
DK2857039T3 (da) 2019-12-16
KR20200029619A (ko) 2020-03-18
TW202041532A (zh) 2020-11-16
SI2857039T1 (sl) 2020-03-31
IL235899B (en) 2019-03-31
SG10201805410XA (en) 2018-08-30
EP3662931A1 (en) 2020-06-10
IL235899A0 (en) 2015-01-29
EP2857039A1 (en) 2015-04-08
JP2016147902A (ja) 2016-08-18
JP6620829B2 (ja) 2019-12-18
CN104602708B (zh) 2021-11-30
PH12014502669A1 (en) 2015-02-02
ES2973070T3 (es) 2024-06-18

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FGA Letters patent sealed or granted (standard patent)
PC Assignment registered

Owner name: OSAKA CITY UNIVERSITY

Free format text: FORMER OWNER(S): TEIJIN PHARMA LIMITED; OSAKA CITY UNIVERSITY

Owner name: TEIJIN LIMITED

Free format text: FORMER OWNER(S): TEIJIN PHARMA LIMITED; OSAKA CITY UNIVERSITY