SI2857039T1 - Terapevtsko sredstvo ali profilaktično sredstvo za demenco - Google Patents

Terapevtsko sredstvo ali profilaktično sredstvo za demenco

Info

Publication number
SI2857039T1
SI2857039T1 SI201331636T SI201331636T SI2857039T1 SI 2857039 T1 SI2857039 T1 SI 2857039T1 SI 201331636 T SI201331636 T SI 201331636T SI 201331636 T SI201331636 T SI 201331636T SI 2857039 T1 SI2857039 T1 SI 2857039T1
Authority
SI
Slovenia
Prior art keywords
agent
dementia
prophylactic
therapeutic agent
therapeutic
Prior art date
Application number
SI201331636T
Other languages
English (en)
Slovenian (sl)
Inventor
Hiroshi Mori
Takami Tomiyama
Yoichi Matsumoto
Hiroshi Eguchi
Yuichi Kunori
Original Assignee
Osaka City University
Teijin Pharma Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osaka City University, Teijin Pharma Limited filed Critical Osaka City University
Publication of SI2857039T1 publication Critical patent/SI2857039T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SI201331636T 2012-05-31 2013-05-30 Terapevtsko sredstvo ali profilaktično sredstvo za demenco SI2857039T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012124336 2012-05-31
EP13797290.7A EP2857039B1 (en) 2012-05-31 2013-05-30 Therapeutic agent or prophylactic agent for dementia
PCT/JP2013/065090 WO2013180238A1 (ja) 2012-05-31 2013-05-30 認知症治療剤又は予防剤

Publications (1)

Publication Number Publication Date
SI2857039T1 true SI2857039T1 (sl) 2020-03-31

Family

ID=49673425

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201331636T SI2857039T1 (sl) 2012-05-31 2013-05-30 Terapevtsko sredstvo ali profilaktično sredstvo za demenco

Country Status (30)

Country Link
US (3) US20150183854A1 (enExample)
EP (2) EP3662931B1 (enExample)
JP (3) JP5971659B2 (enExample)
KR (2) KR102208283B1 (enExample)
CN (1) CN104602708B (enExample)
AR (1) AR091218A1 (enExample)
AU (2) AU2013268364B2 (enExample)
BR (1) BR112014029566A2 (enExample)
CA (1) CA2875205C (enExample)
CY (1) CY1122530T1 (enExample)
DK (1) DK2857039T3 (enExample)
ES (2) ES2973070T3 (enExample)
HR (1) HRP20192267T1 (enExample)
HU (1) HUE046919T2 (enExample)
IL (1) IL235899B (enExample)
LT (1) LT2857039T (enExample)
ME (1) ME03587B (enExample)
MX (1) MX361128B (enExample)
MY (1) MY172458A (enExample)
NZ (1) NZ630536A (enExample)
PH (1) PH12014502669B1 (enExample)
PL (1) PL2857039T3 (enExample)
PT (1) PT2857039T (enExample)
RS (1) RS59802B1 (enExample)
RU (1) RU2657438C2 (enExample)
SG (2) SG10201805410XA (enExample)
SI (1) SI2857039T1 (enExample)
TW (2) TWI777183B (enExample)
WO (1) WO2013180238A1 (enExample)
ZA (1) ZA201409186B (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
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CA2826286C (en) 2011-01-31 2021-09-21 Intellect Neurosciences Inc. Treatment of tauopathies
US9506051B2 (en) * 2011-05-20 2016-11-29 Oligomerix, Inc. Tau protease compositions and methods of use
BR112014029566A2 (pt) * 2012-05-31 2017-07-25 Univ Osaka City agente terapêutico ou agente profilático para desordens cognitivas, anticorpo monoclonal, anticorpo para proteína tau fosforilada, e, peptídeo
MX359555B (es) 2012-07-03 2018-10-02 Univ Washington Anticuerpos para tau.
TW202136296A (zh) * 2014-06-27 2021-10-01 美商C2N醫療診斷有限責任公司 人類化抗-tau抗體
EP3448875A4 (en) * 2016-04-29 2020-04-08 Voyager Therapeutics, Inc. Compositions for the treatment of disease
CN109791149A (zh) * 2016-09-30 2019-05-21 豪夫迈·罗氏有限公司 用于功能分析多特异性分子的基于spr的双重结合测定法
WO2018152359A1 (en) 2017-02-17 2018-08-23 Denali Therapeutics Inc. Anti-tau antibodies and methods of use thereof
JOP20180014A1 (ar) * 2017-02-27 2019-01-30 Teijin Pharma Ltd جسم مضاد متوافق مع البشر لعلاج أو الوقاية من الاضطرابات الإدراكية، وعملية لإنتاجه، وعامل لعلاج أو الوقاية من الاضطرابات الإدراكية باستخدامه
JP6987136B2 (ja) 2017-05-30 2021-12-22 帝人ファーマ株式会社 抗igf−i受容体抗体
JOP20200130A1 (ar) 2017-10-02 2020-05-28 Merck Sharp & Dohme مركبات كرومان مونوباكتام لعلاج العدوى البكتيرية
TWI853617B (zh) 2017-10-16 2024-08-21 日商衛材R&D企管股份有限公司 抗tau抗體及其用途
CN112368300B (zh) 2018-04-06 2024-10-01 帝人制药株式会社 Spns2中和抗体
US20210230598A1 (en) * 2018-07-04 2021-07-29 National University Corporation Tokai National Higher Education And Research System Oligonucleotides for controlling tau splicing, and uses thereof
CN110028583B (zh) * 2019-05-07 2020-09-11 温州医科大学 抗Tau抗体及其在治疗阿尔茨海默病、创伤性脑损伤中的应用
JP7429404B2 (ja) * 2019-08-06 2024-02-08 慶應義塾 タウ関連疾患モデルの製造方法
JP7718270B2 (ja) 2019-09-30 2025-08-05 ニプロ株式会社 血液試料を検体とするタウタンパク質検出方法
IL296611A (en) * 2020-03-19 2022-11-01 Vascular Biosciences Car peptide for improved coronavirus survival
US11702467B2 (en) * 2020-06-25 2023-07-18 Merck Sharp & Dohme Llc High affinity antibodies targeting tau phosphorylated at serine 413
WO2023092004A1 (en) 2021-11-17 2023-05-25 Voyager Therapeutics, Inc. Compositions and methods for the treatment of tau-related disorders
JP2025535203A (ja) 2022-09-15 2025-10-23 ボイジャー セラピューティクス インコーポレイテッド タウ結合化合物
WO2025122634A1 (en) 2023-12-05 2025-06-12 Voyager Therapeutics, Inc. Compositions and methods for the treatment of tau-related disorders

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS587390B2 (ja) 1975-03-11 1983-02-09 ツキシマキカイ カブシキガイシヤ ア−クヨウセツホウホウ
JP3587390B2 (ja) 1994-03-17 2004-11-10 タカラバイオ株式会社 リン酸化アミノ酸誘導体及びリン酸化ペプチド合成方法
WO1997034145A1 (fr) * 1996-03-13 1997-09-18 Mitsubishi Chemical Corporation Anticorps a proteine tau antiphosphorylee et procede de detection de la maladie d'alzheimer l'utilisant
US20080199471A1 (en) * 2002-03-01 2008-08-21 Bernett Matthew J Optimized cd40 antibodies and methods of using the same
US8012936B2 (en) * 2006-03-29 2011-09-06 New York University Tau fragments for immunotherapy
US20070280935A1 (en) * 2006-04-07 2007-12-06 Bernd Bohrmann Antibody that recognizes phosphorylated peptides
AU2007261584A1 (en) * 2006-06-16 2007-12-27 Envivo Pharmaceutical Inc. Transgenic flies expressing tau and amyloid precursor fragment
UA107571C2 (xx) * 2009-04-03 2015-01-26 Фармацевтична композиція
CA2765099A1 (en) * 2009-06-10 2010-12-16 New York University Phosphorylated tau peptide for use in the treatment of tauopathy
US8609097B2 (en) 2009-06-10 2013-12-17 Hoffmann-La Roche Inc. Use of an anti-Tau pS422 antibody for the treatment of brain diseases
CA2826286C (en) * 2011-01-31 2021-09-21 Intellect Neurosciences Inc. Treatment of tauopathies
TR201102696U (tr) * 2011-05-27 2011-06-21 Turhal Sal�H Bağlantısız hareketli ürün reklam standı.
BR112014029566A2 (pt) * 2012-05-31 2017-07-25 Univ Osaka City agente terapêutico ou agente profilático para desordens cognitivas, anticorpo monoclonal, anticorpo para proteína tau fosforilada, e, peptídeo
JOP20180014A1 (ar) * 2017-02-27 2019-01-30 Teijin Pharma Ltd جسم مضاد متوافق مع البشر لعلاج أو الوقاية من الاضطرابات الإدراكية، وعملية لإنتاجه، وعامل لعلاج أو الوقاية من الاضطرابات الإدراكية باستخدامه

Also Published As

Publication number Publication date
KR20150027098A (ko) 2015-03-11
EP2857039A4 (en) 2015-08-26
SG10201805410XA (en) 2018-08-30
RU2657438C2 (ru) 2018-06-13
CY1122530T1 (el) 2021-01-27
RU2014153099A (ru) 2016-07-20
AR091218A1 (es) 2015-01-21
HK1210031A1 (en) 2016-04-15
KR20200029619A (ko) 2020-03-18
PH12014502669A1 (en) 2015-02-02
CA2875205C (en) 2021-07-20
TWI700296B (zh) 2020-08-01
HUE046919T2 (hu) 2020-04-28
SG11201407878VA (en) 2015-01-29
EP2857039B1 (en) 2019-11-20
EP2857039A1 (en) 2015-04-08
IL235899B (en) 2019-03-31
AU2018200413B2 (en) 2019-10-17
CN104602708A (zh) 2015-05-06
TWI777183B (zh) 2022-09-11
JP6620829B2 (ja) 2019-12-18
PH12014502669B1 (en) 2020-02-19
TW201410705A (zh) 2014-03-16
ES2763361T3 (es) 2020-05-28
US20220340646A1 (en) 2022-10-27
CA2875205A1 (en) 2013-12-05
EP3662931B1 (en) 2023-12-06
ES2973070T3 (es) 2024-06-18
PL2857039T3 (pl) 2020-05-18
LT2857039T (lt) 2020-03-10
JP2018111716A (ja) 2018-07-19
KR102208283B1 (ko) 2021-01-26
AU2013268364A1 (en) 2014-12-18
JP5971659B2 (ja) 2016-08-17
AU2013268364B2 (en) 2018-02-08
MX2014014187A (es) 2015-06-04
RS59802B1 (sr) 2020-02-28
JP6406678B2 (ja) 2018-10-17
BR112014029566A2 (pt) 2017-07-25
EP3662931A1 (en) 2020-06-10
JP2016147902A (ja) 2016-08-18
IL235899A0 (en) 2015-01-29
ME03587B (me) 2020-07-20
US20150183854A1 (en) 2015-07-02
US20200148753A1 (en) 2020-05-14
TW202041532A (zh) 2020-11-16
NZ630536A (en) 2017-03-31
ZA201409186B (en) 2015-12-23
HRP20192267T1 (hr) 2020-03-20
PT2857039T (pt) 2020-01-07
DK2857039T3 (da) 2019-12-16
MX361128B (es) 2018-11-28
MY172458A (en) 2019-11-26
KR102133610B1 (ko) 2020-07-14
AU2018200413A1 (en) 2018-02-08
WO2013180238A1 (ja) 2013-12-05
JPWO2013180238A1 (ja) 2016-01-21
CN104602708B (zh) 2021-11-30

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