MX357043B - Inhibidores selectivos de pi3k delta. - Google Patents

Inhibidores selectivos de pi3k delta.

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Publication number
MX357043B
MX357043B MX2014015946A MX2014015946A MX357043B MX 357043 B MX357043 B MX 357043B MX 2014015946 A MX2014015946 A MX 2014015946A MX 2014015946 A MX2014015946 A MX 2014015946A MX 357043 B MX357043 B MX 357043B
Authority
MX
Mexico
Prior art keywords
pi3k delta
delta inhibitors
selective pi3k
methods
selective
Prior art date
Application number
MX2014015946A
Other languages
English (en)
Other versions
MX2014015946A (es
Inventor
Muthuppalaniappan Meyyappan
Kumar Venkara Satya Vakkalanka Swaroop
Nagarathnam Dhanapalan
Original Assignee
Rhizen Pharmaceuticals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54193752&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX357043(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rhizen Pharmaceuticals Sa filed Critical Rhizen Pharmaceuticals Sa
Publication of MX2014015946A publication Critical patent/MX2014015946A/es
Publication of MX357043B publication Critical patent/MX357043B/es

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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Abstract

La presente invención se refiere a inhibidores selectivos de proteína cinasas PI3K delta que tienen un sistema de anillo de 1H-pirazolo[3,4-d]pirimidina, métodos para prepararlos, composiciones farmacéuticas que los contienen y métodos para el tratamiento y/o prevención de enfermedades o trastornos mediados por cinasa con los mismos.
MX2014015946A 2012-07-04 2013-07-02 Inhibidores selectivos de pi3k delta. MX357043B (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN2692CH2012 2012-07-04
IN2693CH2012 2012-07-04
US201261691586P 2012-08-21 2012-08-21
US201261691561P 2012-08-21 2012-08-21
PCT/IB2013/055434 WO2014006572A1 (en) 2012-07-04 2013-07-02 Selective pi3k delta inhibitors

Publications (2)

Publication Number Publication Date
MX2014015946A MX2014015946A (es) 2015-07-17
MX357043B true MX357043B (es) 2018-06-25

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ID=54193752

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014015946A MX357043B (es) 2012-07-04 2013-07-02 Inhibidores selectivos de pi3k delta.

Country Status (32)

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US (7) US9150579B2 (es)
EP (2) EP3260455B1 (es)
JP (2) JP6181173B2 (es)
KR (2) KR101988079B1 (es)
CN (2) CN109970742A (es)
AP (1) AP2015008207A0 (es)
AR (1) AR091677A1 (es)
AU (1) AU2013285081B2 (es)
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