BR112014033055A2 - inibidores seletivos de delta pi3k - Google Patents

inibidores seletivos de delta pi3k Download PDF

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Publication number
BR112014033055A2
BR112014033055A2 BR112014033055A BR112014033055A BR112014033055A2 BR 112014033055 A2 BR112014033055 A2 BR 112014033055A2 BR 112014033055 A BR112014033055 A BR 112014033055A BR 112014033055 A BR112014033055 A BR 112014033055A BR 112014033055 A2 BR112014033055 A2 BR 112014033055A2
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BR
Brazil
Prior art keywords
selective inhibitors
pi3k selective
delta pi3k
delta
inhibitors
Prior art date
Application number
BR112014033055A
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English (en)
Other versions
BR112014033055B1 (pt
BR112014033055A8 (pt
Inventor
Nagarathnam Dhanapalan
Muthuppalaniappan Meyyappan
Kumar Venkata Vakkalanka Swaroop
Original Assignee
Rhizen Pharmaceuticals S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54193752&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112014033055(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rhizen Pharmaceuticals S A filed Critical Rhizen Pharmaceuticals S A
Publication of BR112014033055A2 publication Critical patent/BR112014033055A2/pt
Publication of BR112014033055A8 publication Critical patent/BR112014033055A8/pt
Publication of BR112014033055B1 publication Critical patent/BR112014033055B1/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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  • Diabetes (AREA)
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  • Pulmonology (AREA)
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  • Urology & Nephrology (AREA)
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BR112014033055-7A 2012-07-04 2013-07-02 Compostos inibidores seletivos de delta pi3k, composição farmacêutica contendo os mesmos, e uso dos referidos compostos BR112014033055B1 (pt)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
IN2693/CHE/2012 2012-07-04
IN2692CH2012 2012-07-04
IN2692/CHE/2012 2012-07-04
IN2693CH2012 2012-07-04
US201261691586P 2012-08-21 2012-08-21
US201261691561P 2012-08-21 2012-08-21
US61/691,561 2012-08-21
US61/691,586 2012-08-21
PCT/IB2013/055434 WO2014006572A1 (en) 2012-07-04 2013-07-02 Selective pi3k delta inhibitors

Publications (3)

Publication Number Publication Date
BR112014033055A2 true BR112014033055A2 (pt) 2017-06-27
BR112014033055A8 BR112014033055A8 (pt) 2021-09-08
BR112014033055B1 BR112014033055B1 (pt) 2023-01-31

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BR112014033055-7A BR112014033055B1 (pt) 2012-07-04 2013-07-02 Compostos inibidores seletivos de delta pi3k, composição farmacêutica contendo os mesmos, e uso dos referidos compostos

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