BR112014033055A2 - inibidores seletivos de delta pi3k - Google Patents
inibidores seletivos de delta pi3k Download PDFInfo
- Publication number
- BR112014033055A2 BR112014033055A2 BR112014033055A BR112014033055A BR112014033055A2 BR 112014033055 A2 BR112014033055 A2 BR 112014033055A2 BR 112014033055 A BR112014033055 A BR 112014033055A BR 112014033055 A BR112014033055 A BR 112014033055A BR 112014033055 A2 BR112014033055 A2 BR 112014033055A2
- Authority
- BR
- Brazil
- Prior art keywords
- selective inhibitors
- pi3k selective
- delta pi3k
- delta
- inhibitors
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
- C12Y207/01137—Phosphatidylinositol 3-kinase (2.7.1.137)
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pulmonology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
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Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN2693/CHE/2012 | 2012-07-04 | ||
IN2692CH2012 | 2012-07-04 | ||
IN2692/CHE/2012 | 2012-07-04 | ||
IN2693CH2012 | 2012-07-04 | ||
US201261691586P | 2012-08-21 | 2012-08-21 | |
US201261691561P | 2012-08-21 | 2012-08-21 | |
US61/691,561 | 2012-08-21 | ||
US61/691,586 | 2012-08-21 | ||
PCT/IB2013/055434 WO2014006572A1 (en) | 2012-07-04 | 2013-07-02 | Selective pi3k delta inhibitors |
Publications (3)
Publication Number | Publication Date |
---|---|
BR112014033055A2 true BR112014033055A2 (pt) | 2017-06-27 |
BR112014033055A8 BR112014033055A8 (pt) | 2021-09-08 |
BR112014033055B1 BR112014033055B1 (pt) | 2023-01-31 |
Family
ID=54193752
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014033055-7A BR112014033055B1 (pt) | 2012-07-04 | 2013-07-02 | Compostos inibidores seletivos de delta pi3k, composição farmacêutica contendo os mesmos, e uso dos referidos compostos |
Country Status (32)
Country | Link |
---|---|
US (7) | US9150579B2 (pt) |
EP (2) | EP2870157B1 (pt) |
JP (2) | JP6181173B2 (pt) |
KR (2) | KR102216606B1 (pt) |
CN (2) | CN104470923B (pt) |
AP (1) | AP2015008207A0 (pt) |
AR (1) | AR091677A1 (pt) |
AU (1) | AU2013285081B2 (pt) |
BR (1) | BR112014033055B1 (pt) |
CA (1) | CA2876995C (pt) |
CL (1) | CL2014003511A1 (pt) |
CO (1) | CO7170166A2 (pt) |
CY (2) | CY1119588T1 (pt) |
DK (2) | DK2870157T3 (pt) |
EA (1) | EA028750B1 (pt) |
ES (1) | ES2647416T3 (pt) |
HK (1) | HK1209737A1 (pt) |
HR (1) | HRP20171610T1 (pt) |
HU (1) | HUE034591T2 (pt) |
IL (1) | IL236351B (pt) |
LT (2) | LT2870157T (pt) |
MX (1) | MX357043B (pt) |
MY (1) | MY169987A (pt) |
PH (2) | PH12014502865B1 (pt) |
PL (2) | PL3260455T3 (pt) |
PT (1) | PT2870157T (pt) |
RS (2) | RS58793B1 (pt) |
SG (2) | SG11201408821SA (pt) |
SI (2) | SI3260455T1 (pt) |
TW (1) | TWI598100B (pt) |
WO (1) | WO2014006572A1 (pt) |
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