CO7170166A2 - Inhibidores de pi3k delta selectivos - Google Patents
Inhibidores de pi3k delta selectivosInfo
- Publication number
- CO7170166A2 CO7170166A2 CO15007491A CO15007491A CO7170166A2 CO 7170166 A2 CO7170166 A2 CO 7170166A2 CO 15007491 A CO15007491 A CO 15007491A CO 15007491 A CO15007491 A CO 15007491A CO 7170166 A2 CO7170166 A2 CO 7170166A2
- Authority
- CO
- Colombia
- Prior art keywords
- pi3k inhibitors
- selective delta
- delta pi3k
- selective
- kinases
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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- C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
- C12Y207/01137—Phosphatidylinositol 3-kinase (2.7.1.137)
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Abstract
La presente invención se refiere a inhibidores selectivos de proteínas cinasas delta PT3K que tienen un sistema de anillos de 1H-pirazolo[3,4-d]pirimidina, a los métodos para prepararlos, a composiciones farmacéuticas que los contienen y a los métodos de tratamiento y/o prevención de las enfermedades o trastornos mediados por cinasas con estos.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN2693CH2012 | 2012-07-04 | ||
IN2692CH2012 | 2012-07-04 | ||
US201261691561P | 2012-08-21 | 2012-08-21 | |
US201261691586P | 2012-08-21 | 2012-08-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO7170166A2 true CO7170166A2 (es) | 2015-01-28 |
Family
ID=54193752
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO15007491A CO7170166A2 (es) | 2012-07-04 | 2015-01-15 | Inhibidores de pi3k delta selectivos |
Country Status (32)
Country | Link |
---|---|
US (7) | US9150579B2 (es) |
EP (2) | EP2870157B1 (es) |
JP (2) | JP6181173B2 (es) |
KR (2) | KR102216606B1 (es) |
CN (2) | CN109970742A (es) |
AP (1) | AP2015008207A0 (es) |
AR (1) | AR091677A1 (es) |
AU (1) | AU2013285081B2 (es) |
BR (1) | BR112014033055B1 (es) |
CA (1) | CA2876995C (es) |
CL (1) | CL2014003511A1 (es) |
CO (1) | CO7170166A2 (es) |
CY (2) | CY1119588T1 (es) |
DK (2) | DK3260455T3 (es) |
EA (1) | EA028750B1 (es) |
ES (1) | ES2647416T3 (es) |
HK (1) | HK1209737A1 (es) |
HR (1) | HRP20171610T1 (es) |
HU (1) | HUE034591T2 (es) |
IL (1) | IL236351B (es) |
LT (2) | LT2870157T (es) |
MX (1) | MX357043B (es) |
MY (1) | MY169987A (es) |
PH (2) | PH12014502865A1 (es) |
PL (2) | PL3260455T3 (es) |
PT (1) | PT2870157T (es) |
RS (2) | RS56494B1 (es) |
SG (2) | SG11201408821SA (es) |
SI (2) | SI2870157T1 (es) |
TW (1) | TWI598100B (es) |
WO (1) | WO2014006572A1 (es) |
ZA (2) | ZA201409329B (es) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
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AP2012006294A0 (en) | 2009-11-05 | 2012-06-30 | Rhizen Pharmaceuticals Sa | Novel kinase modulators. |
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