MX276941B - Metodo para producir vitamina. - Google Patents

Metodo para producir vitamina.

Info

Publication number
MX276941B
MX276941B MXPA04002408A MX276941B MX 276941 B MX276941 B MX 276941B MX PA04002408 A MXPA04002408 A MX PA04002408A MX 276941 B MX276941 B MX 276941B
Authority
MX
Mexico
Prior art keywords
geranylgeraniol
microorganism
farnesol
vitamin production
phosphate
Prior art date
Application number
Other languages
English (en)
Inventor
Gabriel G Saucy
Original Assignee
Dcv Inc Haciendo Negocios Como
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dcv Inc Haciendo Negocios Como filed Critical Dcv Inc Haciendo Negocios Como
Publication of MX276941B publication Critical patent/MX276941B/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/08Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/24Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/723,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1085Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/06Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P9/00Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01QANTENNAS, i.e. RADIO AERIALS
    • H01Q1/00Details of, or arrangements associated with, antennas
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
MXPA04002408 1998-07-06 1999-07-06 Metodo para producir vitamina. MX276941B (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US9196498P 1998-07-06 1998-07-06
US9198398P 1998-07-06 1998-07-06
US9195198P 1998-07-06 1998-07-06
PCT/US1999/015264 WO2000001650A1 (en) 1998-07-06 1999-07-06 Method of vitamin production

Publications (1)

Publication Number Publication Date
MX276941B true MX276941B (es) 2010-06-28

Family

ID=27377004

Family Applications (2)

Application Number Title Priority Date Filing Date
MXPA04002408 MX276941B (es) 1998-07-06 1999-07-06 Metodo para producir vitamina.
MXPA01000216 MX219130B (es) 1998-07-06 1999-07-06 Metodo para producir vitamina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MXPA01000216 MX219130B (es) 1998-07-06 1999-07-06 Metodo para producir vitamina.

Country Status (11)

Country Link
EP (3) EP2100963B1 (es)
JP (1) JP4579415B2 (es)
CN (1) CN1330621A (es)
AT (2) ATE490332T1 (es)
AU (1) AU4863099A (es)
CA (2) CA2331343C (es)
DE (1) DE69943009D1 (es)
DK (3) DK2100963T3 (es)
ES (2) ES2534937T3 (es)
MX (2) MX276941B (es)
WO (1) WO2000001650A1 (es)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6531303B1 (en) 1998-07-06 2003-03-11 Arkion Life Sciences Llc Method of producing geranylgeraniol
AU776316B2 (en) 1999-04-15 2004-09-02 Monsanto Company Nucleic acid sequences to proteins involved in tocopherol synthesis
EP1260590B1 (en) * 2000-03-02 2007-02-14 TOUDAI TLO, Ltd. Method of screening substance specifically inhibiting non-mevalonate pathway
US6872815B1 (en) 2000-10-14 2005-03-29 Calgene Llc Nucleic acid sequences to proteins involved in tocopherol synthesis
US20030033626A1 (en) 2000-07-31 2003-02-13 Hahn Frederick M. Manipulation of genes of the mevalonate and isoprenoid pathways to create novel traits in transgenic organisms
AU9052201A (en) 2000-08-07 2002-02-18 Monsanto Technology Llc Methyl-d-erythritol phosphate pathway genes
JP2002253284A (ja) * 2000-12-28 2002-09-10 Toyota Motor Corp 微生物によるゲラニルゲラニオール及びその類縁化合物の製造方法
JP4013535B2 (ja) * 2000-12-28 2007-11-28 トヨタ自動車株式会社 微生物によるプレニルアルコールの高生産方法
JP3894119B2 (ja) * 2000-12-28 2007-03-14 トヨタ自動車株式会社 プレニルアルコールの製造方法
JP3838033B2 (ja) * 2000-12-28 2006-10-25 トヨタ自動車株式会社 プレニルアルコールの製造方法
WO2002053747A1 (en) * 2000-12-28 2002-07-11 Toyota Jidosha Kabushiki Kaisha Process for producing prenyl alcohol
JP2003088368A (ja) * 2001-09-18 2003-03-25 Toyota Motor Corp プレニルアルコールの製造方法
CN1568141B (zh) 2001-05-09 2014-05-07 孟山都技术有限公司 Tyra基因及其应用
US7161061B2 (en) 2001-05-09 2007-01-09 Monsanto Technology Llc Metabolite transporters
ES2311613T3 (es) * 2001-06-06 2009-02-16 Dsm Ip Assets B.V. Produccion mejorada de isoprenoides.
WO2003016482A2 (en) 2001-08-17 2003-02-27 Monsanto Technology Llc Methyltransferase genes and uses thereof
BR0213499A (pt) 2001-10-25 2004-11-03 Monsanto Technology Llc Metiltransferases aromáticas e seu uso
US7172886B2 (en) 2001-12-06 2007-02-06 The Regents Of The University Of California Biosynthesis of isopentenyl pyrophosphate
US7192751B2 (en) 2001-12-06 2007-03-20 The Regents Of The University Of California Biosynthesis of amorpha-4,11-diene
WO2003080647A2 (en) 2002-03-19 2003-10-02 Monsanto Technology, Llc Homogentisate prenyl transferase ('hpt') nucleic acids and polypeptides, and uses thereof
US7687246B2 (en) 2002-06-21 2010-03-30 Dsm Ip Assets B. V. Process for producing carotenoids
US7230165B2 (en) 2002-08-05 2007-06-12 Monsanto Technology Llc Tocopherol biosynthesis related genes and uses thereof
ES2305501T3 (es) * 2002-09-27 2008-11-01 Dsm Ip Assets B.V. Gen escualeno sintasa (sqs).
ATE537269T1 (de) 2004-05-21 2011-12-15 Univ California Verfahren zur verbesserung der herstellung von isoprenoid-zusammensetzungen
US8828684B2 (en) * 2004-07-27 2014-09-09 The Regents Of The University Of California Genetically modified host cells and use of same for producing isoprenoid compounds
AU2006227165B2 (en) 2005-03-18 2011-11-10 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
JP4824985B2 (ja) * 2005-10-13 2011-11-30 株式会社Adeka ファルネシル二リン酸の製造方法
US8691555B2 (en) 2006-09-28 2014-04-08 Dsm Ip Assests B.V. Production of carotenoids in oleaginous yeast and fungi
EP2351845A1 (en) 2007-06-01 2011-08-03 Solazyme, Inc. Renewable chemicals and fuels from oleaginous yeast
BRPI0816951B1 (pt) 2007-09-20 2023-01-17 Amyris, Inc Método para produzir um composto isoprenóide
JP5174430B2 (ja) * 2007-11-06 2013-04-03 花王株式会社 2−フェニルエチルアルコールの製造方法
SG169614A1 (en) * 2008-09-15 2011-04-29 Goodyear Tire & Rubber Conversion of prenyl derivatives to isoprene
CA2745129C (en) * 2008-11-28 2019-05-07 Solazyme, Inc. Production of tailored oils in heterotrophic microorganisms
AU2011257982B2 (en) 2010-05-28 2017-05-25 Corbion Biotech, Inc. Tailored oils produced from recombinant heterotrophic microorganisms
BR122021005283B1 (pt) 2010-06-02 2022-02-22 Evolva, Inc Hospedeiro recombinante que compreende genes recombinantes para produção deesteviol ou glicosídeo de esteviol, método para produzir esteviol, glicosídeo de esteviol ou composição de glicosídeo de esteviol e método para sintetizar esteviol ou glicosídeo de esteviol
ES2909143T3 (es) 2010-11-03 2022-05-05 Corbion Biotech Inc Microbios de Chlorella o Prototheca modificados genéticamente y aceite producido a partir de estos
KR102117225B1 (ko) 2011-02-02 2020-06-02 테라비아 홀딩스 인코포레이티드 재조합 유지성 미생물로부터 생산된 맞춤 오일
CA2834698A1 (en) 2011-05-06 2012-11-15 Solazyme, Inc. Genetically engineered microorganisms that metabolize xylose
MX2013012871A (es) * 2011-05-09 2014-02-17 Amyris Inc Produccion de compuestos derivados de acetil-coenzima a.
EP3009508B1 (en) 2011-08-08 2020-11-25 Evolva SA Recombinant production of steviol glycosides
CA2870364A1 (en) 2012-04-18 2013-10-24 Solazyme, Inc. Recombinant microbes with modified fatty acid synthetic pathway enzymes and uses thereof
CA2899276C (en) 2013-02-06 2022-11-01 Evolva Sa Methods for improved production of rebaudioside d and rebaudioside m
US10017804B2 (en) 2013-02-11 2018-07-10 Evolva Sa Efficient production of steviol glycosides in recombinant hosts
EP2993993A2 (en) 2013-04-26 2016-03-16 Solazyme, Inc. Low polyunsaturated fatty acid oils and uses thereof
BR112016006839A8 (pt) 2013-10-04 2017-10-03 Solazyme Inc Óleos customizados
CN106574255A (zh) 2014-07-10 2017-04-19 泰拉瑞亚控股公司 酮脂酰acp合酶基因及其用途
JP2017528125A (ja) 2014-08-11 2017-09-28 エヴォルヴァ エスアー.Evolva Sa. 組み換え宿主におけるステビオールグリコシドの産生
JP2017528134A (ja) 2014-09-09 2017-09-28 エヴォルヴァ エスアー.Evolva Sa. 組み換え宿主におけるステビオールグリコシドの生産
SG11201705606PA (en) 2015-01-30 2017-08-30 Evolva Sa Production of steviol glycosides in recombinant hosts
EP3271457B1 (en) 2015-03-16 2021-01-20 DSM IP Assets B.V. Udp-glycosyltransferases
EP3332018B1 (en) 2015-08-07 2022-07-27 Evolva SA Production of steviol glycosides in recombinant hosts
CN105153102A (zh) * 2015-09-30 2015-12-16 宜春大海龟生命科学有限公司 以混合生育酚为原料制备α-生育酚的方法
CN109195457A (zh) 2016-04-13 2019-01-11 埃沃尔瓦公司 在重组宿主中产生甜菊醇糖苷
US10815514B2 (en) 2016-05-16 2020-10-27 Evolva Sa Production of steviol glycosides in recombinant hosts
WO2018083338A1 (en) 2016-11-07 2018-05-11 Evolva Sa Production of steviol glycosides in recombinant hosts
EP3720944A1 (en) 2017-12-07 2020-10-14 Zymergen Inc. Engineered biosynthetic pathways for production of (6e)-8-hydroxygeraniol by fermentation
BR112020012704A8 (pt) 2017-12-21 2022-03-03 Zymergen Inc Nepetalactol oxidorredutases, nepetalactol sintases, e micróbios capazes de produzir nepetalactona
CN109609579B (zh) * 2018-12-31 2022-04-05 陕西师范大学 一种产β-胡萝卜素的基因工程菌及其构建方法
CN109884216A (zh) * 2019-04-10 2019-06-14 西南医科大学 一种高效液相色谱测定载药胶束中法尼醛含量的方法
CN110903190B (zh) * 2019-12-09 2022-07-12 万华化学集团股份有限公司 一种维生素a及维生素a酯的制备方法
CN110950791B (zh) * 2019-12-09 2021-12-14 万华化学集团股份有限公司 一种维生素a及维生素a酯制备方法
EP4081505A1 (en) * 2019-12-23 2022-11-02 DSM IP Assets B.V. Dehydrogenation process
CN113621631A (zh) * 2021-08-11 2021-11-09 昆明理工大学 一种甲羟戊酸激酶基因rkmk及其应用
CN113969288B (zh) * 2021-10-29 2024-09-17 湖北冠众通科技有限公司 一种产法尼醇基因工程菌及其构建方法与应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE810299A (fr) * 1974-01-29 1974-05-16 Procede de fabrication de composes contenant un noyau chromane.
US3917710A (en) 1974-05-23 1975-11-04 Eastman Kodak Co Preparation of phytone via the addition of dimethylketene to 4,8-dimethyl-12-oxotridecanal
US3862988A (en) 1974-05-23 1975-01-28 Eastman Kodak Co 4,8 Dimethyl- 12-oxotridecanal
GB1479272A (en) * 1974-12-23 1977-07-13 Kuraray Co Process for preparing a stereospecific farnesol
US4225734A (en) 1978-08-08 1980-09-30 The Regents Of The University Of California Process for producing symmetrical olefins
US4743546A (en) 1985-02-13 1988-05-10 Biotechnica International, Inc. Controlled gene excision
US4871721A (en) 1988-01-11 1989-10-03 E. R. Squibb & Sons, Inc. Phosphorus-containing squalene synthetase inhibitors
US5589372A (en) 1990-09-26 1996-12-31 E. R. Squibb & Sons, Inc. Squalene synthetase
US5460949A (en) 1990-11-15 1995-10-24 Amoco Corporation Method and composition for increasing the accumulation of squalene and specific sterols in yeast
US5475029A (en) 1993-07-08 1995-12-12 The Board Of Trustees Of The Leland Stanford Junior University Farnesyl compounds as cholesterol lowering agents
JP3657298B2 (ja) 1994-11-08 2005-06-08 株式会社クラレ ゲラニルゲラニオ−ルの製造方法
US5556990A (en) 1994-12-16 1996-09-17 Rhone-Poulenc Rorer Pharmaceuticals Inc. Polyarylcarbamoylaza- and -carbamoylalkanedioic acids
JP3120684B2 (ja) 1995-02-14 2000-12-25 トヨタ自動車株式会社 ゲラニルゲラニル二リン酸を合成する変異型ファルネシル二リン酸合成酵素及びそれをコードするdna
JP3151371B2 (ja) * 1995-03-10 2001-04-03 麒麟麦酒株式会社 カロチノイド生産量の増量に有用なdna鎖
CA2192253A1 (en) 1995-12-07 1997-06-08 Susan Ferro-Novick Geranylgeranyl diphosphate synthase proteins, nucleic acid molecules and uses thereof
ES2229288T3 (es) * 1995-12-22 2005-04-16 Dsm Ip Assets B.V. Metodos mejorados para transformar cepas de phaffia, cepas de phaffia transformadas asi obtenidas y dna recombinante en dichos metodos.
US5744341A (en) * 1996-03-29 1998-04-28 University Of Maryland College Park Genes of carotenoid biosynthesis and metabolism and a system for screening for such genes
EP0955363A3 (en) * 1998-05-06 2004-01-28 F. Hoffmann-La Roche Ag Dna sequences encoding enzymes involved in production of isoprenoids

Also Published As

Publication number Publication date
DE69943009D1 (de) 2011-01-13
CA2331343A1 (en) 2000-01-13
ATE537265T1 (de) 2011-12-15
ATE490332T1 (de) 2010-12-15
CA2831321A1 (en) 2000-01-13
DK1947189T3 (da) 2011-03-14
JP4579415B2 (ja) 2010-11-10
EP1947189A3 (en) 2008-10-08
MX219130B (es) 2004-02-10
CA2331343C (en) 2014-01-14
MXPA01000216A (es) 2002-10-17
EP1947189A2 (en) 2008-07-23
EP2100963A1 (en) 2009-09-16
ES2379212T3 (es) 2012-04-23
DK2305825T3 (en) 2015-03-02
AU4863099A (en) 2000-01-24
EP1095002A1 (en) 2001-05-02
DK2100963T3 (da) 2012-04-02
WO2000001650A1 (en) 2000-01-13
EP1947189B1 (en) 2010-12-01
ES2534937T3 (es) 2015-04-30
CA2831321C (en) 2018-05-15
EP1095002A4 (en) 2005-08-03
JP2002519049A (ja) 2002-07-02
CN1330621A (zh) 2002-01-09
EP2100963B1 (en) 2011-12-14

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