MX2021010320A - Administracion de biomoleculas a celulas mononucleares de sangre periferica (pbmc) para modificar una respuesta inmunitaria. - Google Patents

Administracion de biomoleculas a celulas mononucleares de sangre periferica (pbmc) para modificar una respuesta inmunitaria.

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Publication number
MX2021010320A
MX2021010320A MX2021010320A MX2021010320A MX2021010320A MX 2021010320 A MX2021010320 A MX 2021010320A MX 2021010320 A MX2021010320 A MX 2021010320A MX 2021010320 A MX2021010320 A MX 2021010320A MX 2021010320 A MX2021010320 A MX 2021010320A
Authority
MX
Mexico
Prior art keywords
pbmcs
immune response
biomolecules
modify
delivery
Prior art date
Application number
MX2021010320A
Other languages
English (en)
Spanish (es)
Inventor
Armon R Sharei
Scott Loughhead
Howard Bernstein
Katarina Blagovic
Kelan Hlavaty
Matthew Booty
Defne Yarar
Emrah Ilker Ozay
Carolyne Kelly Smith
Original Assignee
Sqz Biotechnologies Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sqz Biotechnologies Co filed Critical Sqz Biotechnologies Co
Publication of MX2021010320A publication Critical patent/MX2021010320A/es

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0648—Splenocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0331—Animal model for proliferative diseases
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    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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MX2021010320A 2019-02-28 2020-02-27 Administracion de biomoleculas a celulas mononucleares de sangre periferica (pbmc) para modificar una respuesta inmunitaria. MX2021010320A (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962812225P 2019-02-28 2019-02-28
EP19161964 2019-03-11
US201962841089P 2019-04-30 2019-04-30
US201962886799P 2019-08-14 2019-08-14
US201962933304P 2019-11-08 2019-11-08
US201962948732P 2019-12-16 2019-12-16
PCT/US2020/020194 WO2020176789A1 (en) 2019-02-28 2020-02-27 Delivery of biomolecules to pbmcs to modify an immune response

Publications (1)

Publication Number Publication Date
MX2021010320A true MX2021010320A (es) 2021-11-12

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MX2021010320A MX2021010320A (es) 2019-02-28 2020-02-27 Administracion de biomoleculas a celulas mononucleares de sangre periferica (pbmc) para modificar una respuesta inmunitaria.

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US (2) US11692168B2 (enExample)
EP (1) EP3931309A4 (enExample)
JP (1) JP7610773B2 (enExample)
KR (1) KR20210134353A (enExample)
CN (1) CN114127267A (enExample)
AU (1) AU2020228648A1 (enExample)
BR (1) BR112021016903A2 (enExample)
CA (1) CA3131701A1 (enExample)
CL (1) CL2021002258A1 (enExample)
CO (1) CO2021012581A2 (enExample)
CR (1) CR20210493A (enExample)
IL (1) IL285809A (enExample)
MX (1) MX2021010320A (enExample)
PE (1) PE20220379A1 (enExample)
PH (1) PH12021500033A1 (enExample)
SG (1) SG11202109333SA (enExample)
TW (1) TWI904084B (enExample)
WO (1) WO2020176789A1 (enExample)
ZA (1) ZA202106308B (enExample)

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US20220296691A1 (en) * 2020-12-29 2022-09-22 Sqz Biotechnologies Company Methods for treating cancer with activating antigen carriers
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US12150982B2 (en) * 2020-12-29 2024-11-26 Stemcell Technologies Canada Inc. Formulations of PBMCs
EP4271711A1 (en) * 2020-12-29 2023-11-08 SQZ Biotechnologies Company Methods for treating cancers with modified pbmcs
US20240182851A1 (en) * 2021-04-02 2024-06-06 Sqz Biotechnologies Company Reprogramming of cells and uses thereof
JP2024526851A (ja) * 2021-07-19 2024-07-19 ユニバーシティ オブ ピッツバーグ － オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション モノカルボン酸トランスポーター１１の阻害によるがんの細胞治療
US20250327027A1 (en) 2021-07-29 2025-10-23 Stemcell Technologies Canada Inc. Methods to generate enhanced tumor infiltrating lymphocytes through microfluidic delivery
JP2024545582A (ja) 2021-11-11 2024-12-10 ステムセル テクノロジーズ カナダ インコーポレイテッド マイクロ流体送達による増強された腫瘍浸潤リンパ球を作製する方法
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