FR2569477B1 - Appareil et procede pour la determination de la deformabilite des globules rouges du sang - Google Patents

Appareil et procede pour la determination de la deformabilite des globules rouges du sang

Info

Publication number
FR2569477B1
FR2569477B1 FR8413171A FR8413171A FR2569477B1 FR 2569477 B1 FR2569477 B1 FR 2569477B1 FR 8413171 A FR8413171 A FR 8413171A FR 8413171 A FR8413171 A FR 8413171A FR 2569477 B1 FR2569477 B1 FR 2569477B1
Authority
FR
France
Prior art keywords
deformability
determining
blood cells
red blood
red
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8413171A
Other languages
English (en)
Other versions
FR2569477A1 (fr
Inventor
Maxime Francois Hanss
Jean Roger Guillet
Didier Philibert Vassaux
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite Paris 5 Rene Descartes
Original Assignee
Universite Paris 5 Rene Descartes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite Paris 5 Rene Descartes filed Critical Universite Paris 5 Rene Descartes
Priority to FR8413171A priority Critical patent/FR2569477B1/fr
Priority to DE3529792A priority patent/DE3529792C2/de
Priority to GB08521029A priority patent/GB2163555B/en
Publication of FR2569477A1 publication Critical patent/FR2569477A1/fr
Application granted granted Critical
Publication of FR2569477B1 publication Critical patent/FR2569477B1/fr
Priority to US07/136,532 priority patent/US4835457A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
    • G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
    • G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
    • G01N15/13—Details pertaining to apertures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
    • G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
    • G01N15/134—Devices using two or more apertures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
FR8413171A 1984-08-24 1984-08-24 Appareil et procede pour la determination de la deformabilite des globules rouges du sang Expired FR2569477B1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
FR8413171A FR2569477B1 (fr) 1984-08-24 1984-08-24 Appareil et procede pour la determination de la deformabilite des globules rouges du sang
DE3529792A DE3529792C2 (de) 1984-08-24 1985-08-20 Verfahren und Vorrichtung zum Bestimmen der Verformbarkeit von roten Blutkörperchen
GB08521029A GB2163555B (en) 1984-08-24 1985-08-22 Apparatus and process for determining the deformability of the red corpuscles in the blood
US07/136,532 US4835457A (en) 1984-08-24 1987-12-22 Apparatus and process for determining the deformability of the red corpuscles in the blood

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8413171A FR2569477B1 (fr) 1984-08-24 1984-08-24 Appareil et procede pour la determination de la deformabilite des globules rouges du sang

Publications (2)

Publication Number Publication Date
FR2569477A1 FR2569477A1 (fr) 1986-02-28
FR2569477B1 true FR2569477B1 (fr) 1987-01-02

Family

ID=9307201

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8413171A Expired FR2569477B1 (fr) 1984-08-24 1984-08-24 Appareil et procede pour la determination de la deformabilite des globules rouges du sang

Country Status (4)

Country Link
US (1) US4835457A (fr)
DE (1) DE3529792C2 (fr)
FR (1) FR2569477B1 (fr)
GB (1) GB2163555B (fr)

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DE3802221C2 (de) * 1988-01-26 1996-08-01 Stephan Prof Dr Rer Nat Nees Verfahren zur Messung der Volumenflußrate von Zellen einer Zellsuspension, von Vollblut-Zellen oder von Komponenten des Blutplasmas
GB2232769B (en) * 1989-06-13 1994-06-22 Timothy Charles Fisher Counting and volume measurement of particles and biological cells,and determination of their deformability
US5376878A (en) * 1991-12-12 1994-12-27 Fisher; Timothy C. Multiple-aperture particle counting sizing and deformability-measuring apparatus
US5532139A (en) * 1992-10-30 1996-07-02 Micro-Med, Inc. Micro lysis-analysis process to measure cell characteristics and diagnose diseases
US5955295A (en) * 1992-10-30 1999-09-21 Micro-Med, Inc. Micro lysis-analysis process to measure cell characteristics and diagnose diseases
US5610027A (en) * 1992-10-30 1997-03-11 Micro-Med, Inc. Microphoto lysis-anlaysis process to measure cell characteristics
DE4344986A1 (de) * 1993-12-30 1995-07-06 Richard Dr Knedla Ein Verfahren sowie die technische Lösung und Vorrichtung zur Durchführung einer medizinischen Elektrotherapie sowie Schnelldiagnostik bei der Behandlung von schweren Krankheiten, wie AIDS, Krebs, Tbc, Neurofibromatose etc.
DE19610146C1 (de) * 1996-03-15 1997-06-12 Wolf Prof Dr Bertling Vorrichtung zur Untersuchung von biologischen und medizinischen Proben
GB9624096D0 (en) * 1996-11-20 1997-01-08 Microbial Systems Ltd Apparatus and method of use thereof
GB2337598B (en) * 1996-11-20 2000-08-16 Microbial Systems Ltd Particle sizing apparatus
US6418802B1 (en) * 1996-11-21 2002-07-16 Michael Anthony Wood Particle sizing apparatus and method of use thereof
GB9930718D0 (en) * 1999-12-24 2000-02-16 Central Research Lab Ltd Apparatus for and method of making electrical measurements on objects
GB9930719D0 (en) * 1999-12-24 2000-02-16 Central Research Lab Ltd Apparatus for and method of making electrical measurements on an object in a m edium
EP1540324A2 (fr) * 2002-06-07 2005-06-15 Picosep A/S Procede et systeme pour focalisation ipoeletrique en plusieures etapes
EP1530710B1 (fr) * 2002-06-11 2017-08-09 Koninklijke Philips N.V. Cartouche jetable permettant de caracteriser des particules en suspension dans un liquide
JP5096170B2 (ja) 2005-02-10 2012-12-12 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ デュアルサンプルカートリッジ及び液体中の粒子を特徴付ける方法
CA2855108A1 (fr) * 2005-02-10 2006-08-17 Koninklijke Philips Electronics N.V. Cartouche echantillon double et procede de caracterisation d'une particule dans un liquide
KR100760309B1 (ko) 2005-07-06 2007-10-05 한국과학기술원 미소필터를 이용한 미소입자 변형성 분석기
BRPI0715801A2 (pt) * 2006-08-22 2013-07-16 Koninkl Philips Electronics Nv sistema e mÉtodo para determinar propriedades de partÍculas, sistema de processamento para executar um mÉtodo, produto de programa de computador, dispositivo de armazenamento de dados de legÍvel por mÁquina, e, transmissço dos produtos de programa de computador
CA2852672C (fr) 2011-10-17 2021-07-20 Massachusetts Institute Of Technology Systeme microfluidique et procede d'alimentation de charge utile a une cellule par la creation de perturbations dans une membrane de la cellule
JP6502940B2 (ja) 2013-08-16 2019-04-17 マサチューセッツ インスティテュート オブ テクノロジー 細胞への物質の選択的送達
KR20170074235A (ko) 2014-10-31 2017-06-29 메사추세츠 인스티튜트 오브 테크놀로지 면역 세포로의 생체분자의 전달
CN113897285A (zh) 2014-11-14 2022-01-07 麻省理工学院 化合物和组合物向细胞中的破坏和场实现的递送
CN107250373A (zh) 2015-01-12 2017-10-13 麻省理工学院 通过微流体递送实现的基因编辑
EP4257675A3 (fr) 2015-07-09 2024-01-03 Massachusetts Institute of Technology Administration de substances à des cellules anucléées
US11613759B2 (en) 2015-09-04 2023-03-28 Sqz Biotechnologies Company Intracellular delivery of biomolecules to cells comprising a cell wall
CN109799181A (zh) * 2019-01-29 2019-05-24 桂林优利特医疗电子有限公司 一种基于额定数量的血细胞计数装置和方法
SG11202109333SA (en) 2019-02-28 2021-09-29 Sqz Biotechnologies Co Delivery of biomolecules to pbmcs to modify an immune response
CA3136296A1 (fr) 2019-04-08 2020-10-15 Sqz Biotechnologies Company Cartouche destinee a etre utilisee dans un systeme de livraison d'une charge utile dans une cellule
CN113866240B (zh) * 2021-09-27 2024-05-28 四川成电医联科技咨询有限公司 基于测量电阻抗修正的白细胞检测电极结构和方法
JP2024081540A (ja) * 2022-12-06 2024-06-18 株式会社アドバンテスト ポアチップおよび微粒子測定システム

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE8313231U1 (de) * 1983-11-10 Phywe AG, 3400 Göttingen Vorrichtung zum Zählen von Blutkörperchen
US3815024A (en) * 1970-02-20 1974-06-04 Gen Electric Particle analyzer
US3791933A (en) * 1971-02-25 1974-02-12 Geomet Rapid methods for assay of enzyme substrates and metabolites
US3815022A (en) * 1972-10-04 1974-06-04 Gen Electric Method and apparatus for measuring small aspherical particles
DE2502621C3 (de) * 1975-01-23 1978-09-14 Kernforschungsanlage Juelich Gmbh, 5170 Juelich Messung elastischer und dielektrischer Eigenschaften der Membran lebender Zellen
FR2463927A1 (fr) * 1979-08-17 1981-02-27 Hanss Maxime Appareil et procede pour la determination des proprietes rheologiques des fluides biologiques
DE3215719C2 (de) * 1982-04-28 1984-01-26 Holger Dr. 5100 Aachen Kiesewetter Meßeinrichtung zur Messung des Verformungsvermögens von roten Blutkörperchen

Also Published As

Publication number Publication date
GB2163555A (en) 1986-02-26
DE3529792C2 (de) 1994-02-17
GB2163555B (en) 1989-04-26
GB8521029D0 (en) 1985-09-25
DE3529792A1 (de) 1986-02-27
FR2569477A1 (fr) 1986-02-28
US4835457A (en) 1989-05-30

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