MX2022006444A - Linfocitos t activados por bite ex vivo. - Google Patents

Linfocitos t activados por bite ex vivo.

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Publication number
MX2022006444A
MX2022006444A MX2022006444A MX2022006444A MX2022006444A MX 2022006444 A MX2022006444 A MX 2022006444A MX 2022006444 A MX2022006444 A MX 2022006444A MX 2022006444 A MX2022006444 A MX 2022006444A MX 2022006444 A MX2022006444 A MX 2022006444A
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Mexico
Prior art keywords
cells
methods
cancer
killing
cell
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MX2022006444A
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English (en)
Inventor
Nobell Juan Antonio Ballesteros
Ramos Daniel Primo
Guillén Julián Gorrochategui
Mateos Alicia Robles
Campo Pilar Hernández
Teresa Ann Bennet
González Cristina Gómez
López Joaquín Martínez
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Vivia Biotech Sl
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Application filed by Vivia Biotech Sl filed Critical Vivia Biotech Sl
Publication of MX2022006444A publication Critical patent/MX2022006444A/es

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Abstract

La generación y la identificación de células efectoras inmunitarias muy eficaces en términos de actividad de destrucción de células diana se puede potenciar mediante la optimización de la proximidad entre una célula diana y una célula efectora inmunitaria. Los linfocitos T destructores del cáncer descritos en el presente documento pueden proporcionar terapias altamente eficaces para diversos tipos de cáncer, por ejemplo, cánceres sólidos, cánceres hematológicos y formas metastásicas de los mismos. En el presente documento, se proporcionan métodos ex vivo de generación de linfocitos T destructores del cáncer, composiciones que comprenden dichas células inmunitarias; métodos de uso de las células, métodos para seleccionar agentes óptimos para potenciar la actividad de destrucción de las células diana, métodos para seleccionar una célula inmunitaria optimizada y métodos de uso de este enfoque para evaluar la capacidad de respuesta del paciente a otras terapias contra el cáncer.
MX2022006444A 2016-04-13 2018-10-11 Linfocitos t activados por bite ex vivo. MX2022006444A (es)

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US201662321964P 2016-04-13 2016-04-13

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MX2022006444A MX2022006444A (es) 2016-04-13 2018-10-11 Linfocitos t activados por bite ex vivo.

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Country Link
US (1) US20190218515A1 (es)
EP (1) EP3445391A1 (es)
JP (2) JP7038353B2 (es)
KR (1) KR20180133442A (es)
CN (2) CN109789195A (es)
AU (2) AU2017249698B2 (es)
CA (1) CA3020830A1 (es)
IL (2) IL262359B (es)
MX (2) MX2018012488A (es)
SG (1) SG11201808909WA (es)
WO (1) WO2017178572A1 (es)

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