PE20171734A1 - Anticuerpos monoclonales especificos del antigeno m del virus metapneumovirus humano (hmpv) y su uso en un metodo de diagnostico - Google Patents
Anticuerpos monoclonales especificos del antigeno m del virus metapneumovirus humano (hmpv) y su uso en un metodo de diagnosticoInfo
- Publication number
- PE20171734A1 PE20171734A1 PE2017000986A PE2017000986A PE20171734A1 PE 20171734 A1 PE20171734 A1 PE 20171734A1 PE 2017000986 A PE2017000986 A PE 2017000986A PE 2017000986 A PE2017000986 A PE 2017000986A PE 20171734 A1 PE20171734 A1 PE 20171734A1
- Authority
- PE
- Peru
- Prior art keywords
- hmpv
- diagnostic method
- antigen
- monoclonal antibodies
- seq
- Prior art date
Links
- 238000002405 diagnostic procedure Methods 0.000 title abstract 2
- 241000342334 Human metapneumovirus Species 0.000 title 2
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 241000351643 Metapneumovirus Species 0.000 abstract 1
- 241001529936 Murinae Species 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000003550 marker Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/115—Paramyxoviridae, e.g. parainfluenza virus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
SE REFIERE A UN ANTICUERPO MONOCLONAL MURINO O UN FRAGMENTO DEL MISMO QUE SE UNE A LA PROTEINA M DEL VIRUS RESPIRATORIO METAPNEUMOVIRUS HUMANO (hMPV), EL CUAL COMPRENDE i) UNA REGION VARIABLE DE LA CADENA PESADA QUE TIENE UNA SECUENCIA CON 99% DE IDENTIDAD CON LA SEQ ID N°: 1 O 5, Y ii) UNA REGION VARIABLE DE LA CADENA LIGERA QUE TIENE UNA SECUENCIA CON 99% DE IDENTIDAD CON LA SEQ ID N°: 2 O 6; DONDE DICHO ANTICUERPO ES SECRETADO POR LINEAS CELULARES DE HIBRIDOMAS DENOMINADOS 3G8/C11 Y 7G4/A12. TAMBIEN SE REFIERE A UN METODO DE DIAGNOSTICO IN VITRO DE INFECCION POR hMPV EN UNA MUESTRA BIOLOGICA, DONDE EL ANTICUERPO SE ENCUENTRA CONJUGADO CON UN MARCADOR TAL COMO FLUOROFOROS, RADIOISOTOPOS, ENZIMAS, ENTRE OTROS, QUE PERMITEN SU DETECCION
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CL2014003373A CL2014003373A1 (es) | 2014-12-11 | 2014-12-11 | Anticuerpos monoclonales especificos para el antígeno m del virus metapneumovirus humano (hmpv), producidos y secretados por hibridomas celulares , útiles para la deteccion y el diagnostico de la infeccion causada por hmpv. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20171734A1 true PE20171734A1 (es) | 2017-12-04 |
Family
ID=53404103
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2017000986A PE20171734A1 (es) | 2014-12-11 | 2015-02-02 | Anticuerpos monoclonales especificos del antigeno m del virus metapneumovirus humano (hmpv) y su uso en un metodo de diagnostico |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US9995747B2 (es) |
| EP (2) | EP3231815A4 (es) |
| KR (1) | KR102339334B1 (es) |
| CN (1) | CN107207584B (es) |
| AR (1) | AR102966A1 (es) |
| BR (1) | BR112017012511B1 (es) |
| CA (2) | CA2970482A1 (es) |
| CL (1) | CL2014003373A1 (es) |
| CO (1) | CO2017005781A2 (es) |
| DE (1) | DE112015005539T5 (es) |
| GB (2) | GB2568617A (es) |
| MX (1) | MX2017007611A (es) |
| PE (1) | PE20171734A1 (es) |
| RU (1) | RU2698052C2 (es) |
| UY (1) | UY36431A (es) |
| WO (1) | WO2016092380A1 (es) |
| ZA (2) | ZA201704530B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3111336A1 (en) * | 2018-09-03 | 2020-03-12 | Pontificia Universidad Catolica De Chile | Specific monoclonal antibody against the n antigen of human respiratory syncytial virus (hrsv) useful for treating infection, detection thereof and diagnosis |
| JP7274904B2 (ja) * | 2019-03-26 | 2023-05-17 | 田中貴金属工業株式会社 | ヒトメタニューモウイルス検出用試薬 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2494987A1 (en) * | 2003-04-25 | 2012-09-05 | MedImmune Vaccines, Inc. | Metapneumovirus strains and their use in vaccine formulations and as vectors for expression of antigenic sequences and methods for propagating virus |
| EP1473037A1 (en) * | 2003-05-02 | 2004-11-03 | Vironovative B.V. | Treatment of hPMV infections with Ribavirin |
| WO2007038862A1 (en) * | 2005-10-03 | 2007-04-12 | Seneca College Of Applied Arts & Technology | Nucleic acid immunological composition for human metapneumovirus |
| US8492097B2 (en) | 2006-04-24 | 2013-07-23 | Diagnostic Hybrids, Inc. | Compositions and methods for human metapneumovirus monoclonal antibodies |
| KR20090088871A (ko) * | 2006-10-04 | 2009-08-20 | 더 스크립스 리서치 인스티튜트 | 인간 메타뉴모바이러스를 중화시키는 인간 항체 |
| WO2008148170A1 (en) * | 2007-06-08 | 2008-12-11 | The University Of Queensland | Human metapneumovirus immunogenic peptides, compositions, and methods of use |
| CN102145167A (zh) * | 2010-02-05 | 2011-08-10 | 重庆医科大学附属儿童医院 | 重组人类偏肺病毒疫苗 |
| CL2011003002A1 (es) * | 2011-11-25 | 2012-05-25 | Univ Pontificia Catolica Chile | Anticuerpo monoclonal o un fragmento del mismo que se une a la proteina m2-1 del virus respiratorio sincicial (vrs) humano; secuencias nucleotidicas; composicion farmaceutica; metodo de diagnostico de infeccion producida por vrs; kit; y uso de dicho anticuerpo para preparar un medicamento. |
-
2014
- 2014-12-11 CL CL2014003373A patent/CL2014003373A1/es unknown
-
2015
- 2015-02-02 CN CN201580073977.9A patent/CN107207584B/zh active Active
- 2015-02-02 EP EP15866549.7A patent/EP3231815A4/en active Pending
- 2015-02-02 KR KR1020177019261A patent/KR102339334B1/ko active IP Right Grant
- 2015-02-02 BR BR112017012511-0A patent/BR112017012511B1/pt active IP Right Grant
- 2015-02-02 RU RU2017120228A patent/RU2698052C2/ru active
- 2015-02-02 US US15/535,170 patent/US9995747B2/en active Active
- 2015-02-02 CA CA2970482A patent/CA2970482A1/en active Pending
- 2015-02-02 GB GB1901874.6A patent/GB2568617A/en not_active Withdrawn
- 2015-02-02 MX MX2017007611A patent/MX2017007611A/es unknown
- 2015-02-02 WO PCT/IB2015/050790 patent/WO2016092380A1/es active Application Filing
- 2015-02-02 GB GB1709129.9A patent/GB2547603B/en active Active
- 2015-02-02 PE PE2017000986A patent/PE20171734A1/es unknown
- 2015-02-02 CA CA3168348A patent/CA3168348A1/en active Pending
- 2015-02-02 EP EP18188183.0A patent/EP3495386A1/en active Pending
- 2015-02-02 DE DE112015005539.8T patent/DE112015005539T5/de active Pending
- 2015-12-10 AR ARP150104031A patent/AR102966A1/es unknown
- 2015-12-11 UY UY0001036431A patent/UY36431A/es unknown
-
2017
- 2017-06-12 CO CONC2017/0005781A patent/CO2017005781A2/es unknown
- 2017-07-04 ZA ZA2017/04530A patent/ZA201704530B/en unknown
-
2018
- 2018-07-09 ZA ZA2018/04550A patent/ZA201804550B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB201901874D0 (en) | 2019-04-03 |
| BR112017012511A2 (pt) | 2018-02-27 |
| EP3231815A4 (en) | 2018-02-21 |
| EP3231815A1 (en) | 2017-10-18 |
| UY36431A (es) | 2016-01-29 |
| MX2017007611A (es) | 2017-09-18 |
| CN107207584B (zh) | 2021-01-08 |
| ZA201804550B (en) | 2019-09-25 |
| GB2547603A (en) | 2017-08-23 |
| CA2970482A1 (en) | 2016-06-16 |
| CA3168348A1 (en) | 2016-06-16 |
| GB201709129D0 (en) | 2017-07-26 |
| US9995747B2 (en) | 2018-06-12 |
| CO2017005781A2 (es) | 2017-08-31 |
| KR102339334B1 (ko) | 2021-12-14 |
| RU2698052C2 (ru) | 2019-08-21 |
| ZA201704530B (en) | 2018-11-28 |
| CL2014003373A1 (es) | 2015-04-10 |
| US20170343546A1 (en) | 2017-11-30 |
| BR112017012511B1 (pt) | 2023-12-12 |
| RU2017120228A3 (es) | 2019-01-11 |
| CN107207584A (zh) | 2017-09-26 |
| WO2016092380A1 (es) | 2016-06-16 |
| GB2547603B (en) | 2019-10-30 |
| RU2017120228A (ru) | 2019-01-11 |
| EP3495386A1 (en) | 2019-06-12 |
| KR20170086668A (ko) | 2017-07-26 |
| AR102966A1 (es) | 2017-04-05 |
| DE112015005539T5 (de) | 2017-08-31 |
| GB2568617A (en) | 2019-05-22 |
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