MX2021001284A - Complejos dirigidos al musculo y sus usos para el tratamiento de distrofia muscular facioescapulohumeral. - Google Patents

Complejos dirigidos al musculo y sus usos para el tratamiento de distrofia muscular facioescapulohumeral.

Info

Publication number
MX2021001284A
MX2021001284A MX2021001284A MX2021001284A MX2021001284A MX 2021001284 A MX2021001284 A MX 2021001284A MX 2021001284 A MX2021001284 A MX 2021001284A MX 2021001284 A MX2021001284 A MX 2021001284A MX 2021001284 A MX2021001284 A MX 2021001284A
Authority
MX
Mexico
Prior art keywords
muscle
muscular dystrophy
facioscapulohumeral muscular
muscle targeting
targeting complexes
Prior art date
Application number
MX2021001284A
Other languages
English (en)
Spanish (es)
Inventor
Romesh R Subramanian
Mohammed T Qatanani
Timothy Weeden
Original Assignee
Dyne Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dyne Therapeutics Inc filed Critical Dyne Therapeutics Inc
Publication of MX2021001284A publication Critical patent/MX2021001284A/es

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    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2881—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD71
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
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    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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MX2021001284A 2018-08-02 2019-08-02 Complejos dirigidos al musculo y sus usos para el tratamiento de distrofia muscular facioescapulohumeral. MX2021001284A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862713933P 2018-08-02 2018-08-02
PCT/US2019/044990 WO2020028864A1 (en) 2018-08-02 2019-08-02 Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy

Publications (1)

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MX2021001284A true MX2021001284A (es) 2021-07-15

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MX2021001284A MX2021001284A (es) 2018-08-02 2019-08-02 Complejos dirigidos al musculo y sus usos para el tratamiento de distrofia muscular facioescapulohumeral.

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US (12) US20220193250A1 (OSRAM)
EP (1) EP3830259A4 (OSRAM)
JP (2) JP7856428B2 (OSRAM)
KR (1) KR20210081324A (OSRAM)
CN (1) CN112912499A (OSRAM)
AU (1) AU2019316103B2 (OSRAM)
CA (1) CA3108289A1 (OSRAM)
EA (1) EA202190416A1 (OSRAM)
IL (1) IL280426A (OSRAM)
MX (1) MX2021001284A (OSRAM)
SG (1) SG11202100928QA (OSRAM)
WO (1) WO2020028864A1 (OSRAM)

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