MX2017007243A - Metodos para desarrollo y uso de unidades micro-agregadas de celulas funcionales polarizadas minimamente en aplicaciones en tejidos utilizando celulas troncales epiteliales que expresan lgr4, lgr5 y lgr6. - Google Patents

Metodos para desarrollo y uso de unidades micro-agregadas de celulas funcionales polarizadas minimamente en aplicaciones en tejidos utilizando celulas troncales epiteliales que expresan lgr4, lgr5 y lgr6.

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Publication number
MX2017007243A
MX2017007243A MX2017007243A MX2017007243A MX2017007243A MX 2017007243 A MX2017007243 A MX 2017007243A MX 2017007243 A MX2017007243 A MX 2017007243A MX 2017007243 A MX2017007243 A MX 2017007243A MX 2017007243 A MX2017007243 A MX 2017007243A
Authority
MX
Mexico
Prior art keywords
applications
micro
troncal
epitelial
lgr6
Prior art date
Application number
MX2017007243A
Other languages
English (en)
Spanish (es)
Inventor
M Lough Denver
Original Assignee
Polarityte Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56078499&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2017007243(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Polarityte Inc filed Critical Polarityte Inc
Publication of MX2017007243A publication Critical patent/MX2017007243A/es

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0625Epidermal cells, skin cells; Cells of the oral mucosa
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813Epithelial cells, e.g. keratinocytes, urothelial cells
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/12Chemical aspects of preservation
    • A01N1/122Preservation or perfusion media
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/12Chemical aspects of preservation
    • A01N1/122Preservation or perfusion media
    • A01N1/125Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/362Skin, e.g. dermal papillae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412Tissue-regenerating or healing or proliferative agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2513/003D culture

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Botany (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Developmental Biology & Embryology (AREA)
MX2017007243A 2014-12-02 2015-12-01 Metodos para desarrollo y uso de unidades micro-agregadas de celulas funcionales polarizadas minimamente en aplicaciones en tejidos utilizando celulas troncales epiteliales que expresan lgr4, lgr5 y lgr6. MX2017007243A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462086526P 2014-12-02 2014-12-02
US14/954,335 US10926001B2 (en) 2014-12-02 2015-11-30 Methods related to minimally polarized functional units
PCT/US2015/063114 WO2016089825A1 (en) 2014-12-02 2015-12-01 Methods for development and use of minimally polarized function cell micro-aggregate units in tissue applications using lgr4, lgr5 and lgr6 expressing epithelial stem cells

Publications (1)

Publication Number Publication Date
MX2017007243A true MX2017007243A (es) 2018-01-25

Family

ID=56078499

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2017007243A MX2017007243A (es) 2014-12-02 2015-12-01 Metodos para desarrollo y uso de unidades micro-agregadas de celulas funcionales polarizadas minimamente en aplicaciones en tejidos utilizando celulas troncales epiteliales que expresan lgr4, lgr5 y lgr6.
MX2023001655A MX2023001655A (es) 2014-12-02 2017-06-05 Composiciones que comprenden celulas troncales que expresan lgr y usos de las mismas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2023001655A MX2023001655A (es) 2014-12-02 2017-06-05 Composiciones que comprenden celulas troncales que expresan lgr y usos de las mismas.

Country Status (21)

Country Link
US (7) US10926001B2 (enExample)
EP (2) EP3227431B1 (enExample)
JP (3) JP6791854B2 (enExample)
KR (5) KR20210043024A (enExample)
CN (1) CN107250348B (enExample)
AU (3) AU2015355187C1 (enExample)
BR (1) BR112017011808A2 (enExample)
CA (1) CA2969707C (enExample)
CO (1) CO2017006640A2 (enExample)
CR (1) CR20170296A (enExample)
EA (1) EA201791125A1 (enExample)
GB (2) GB2549872A (enExample)
HK (1) HK1250515A1 (enExample)
IL (2) IL252613B (enExample)
MX (2) MX2017007243A (enExample)
MY (1) MY184931A (enExample)
NZ (2) NZ755260A (enExample)
PH (1) PH12017501009B1 (enExample)
SG (2) SG10201914058QA (enExample)
WO (1) WO2016089825A1 (enExample)
ZA (1) ZA201703907B (enExample)

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* Cited by examiner, † Cited by third party
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EP3595440A2 (en) * 2017-03-14 2020-01-22 Juno Therapeutics, Inc. Methods for cryogenic storage
CR20200366A (es) * 2018-01-26 2020-10-05 Polarityte Inc Sustrato acelarante de biomaterial con interfaz compuesta
AU2019212976A1 (en) * 2018-01-26 2020-07-23 Polarityte, Inc. Complex living interface-coordinated self-assembling materials (CLICSAM)
FR3082123B1 (fr) 2018-06-07 2020-10-16 Urgo Rech Innovation Et Developpement Pansement cellularise et son procede de fabrication
JP2024006681A (ja) * 2022-07-04 2024-01-17 学校法人近畿大学 生体材料
WO2025166131A1 (en) * 2024-02-01 2025-08-07 Board Of Regents, The University Of Texas System Compositions and methods for treating bone and muscle injuries

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US20040126881A1 (en) * 2002-09-06 2004-07-01 Vincent Ronfard Fibrin cell supports and methods of use thereof
WO2006008009A2 (en) 2004-07-23 2006-01-26 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with leucine-rich repeat-containing gpcr 6 (lgr6)
US20060154365A1 (en) 2004-08-30 2006-07-13 Anthony Ratcliffe Cultured three dimensional tissues and uses thereof
EP1942957B1 (en) * 2005-10-27 2012-07-11 Coloplast A/S Biodegradable scaffold with ecm material
WO2008008009A1 (en) 2006-07-13 2008-01-17 St. Jude Medical Ab Medical information management in a patient information hub system
US8366723B2 (en) 2006-08-03 2013-02-05 Rassman Licensing, Llc Hair harvesting device and method with localized subsurface dermal fluid insertion
US7998737B2 (en) 2006-09-12 2011-08-16 Deutsches Krebsforschungszentrum Cell culture of keratinocytes under non-differentiating conditions
GB201111244D0 (en) 2011-06-30 2011-08-17 Konink Nl Akademie Van Wetenschappen Knaw Culture media for stem cells
US9752124B2 (en) 2009-02-03 2017-09-05 Koninklijke Nederlandse Akademie Van Wetenschappen Culture medium for epithelial stem cells and organoids comprising the stem cells
EP2412800A1 (en) 2010-07-29 2012-02-01 Koninklijke Nederlandse Akademie van Wetenschappen Liver organoid, uses thereof and culture method for obtaining them
FI20095355A0 (fi) 2009-04-01 2009-04-01 Helsingin Yliopisto Regeneroituva aktiivinen matriisi ja sen käytöt
US20110076303A1 (en) 2009-06-25 2011-03-31 Tokuro Iwabuchi Methods for Screening for Anti-Graying Agents on the Basis of AFF-4
US20110130711A1 (en) 2009-11-19 2011-06-02 Follica, Inc. Hair growth treatment
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Also Published As

Publication number Publication date
AU2019240603A1 (en) 2019-10-17
IL287488A (en) 2021-12-01
MX2023001655A (es) 2023-04-24
ZA201703907B (en) 2023-03-29
CO2017006640A2 (es) 2017-11-21
CR20170296A (es) 2018-01-25
EP3227431A4 (en) 2019-01-02
JP6791854B2 (ja) 2020-11-25
AU2023202857A1 (en) 2023-05-25
US10926001B2 (en) 2021-02-23
AU2015355187B2 (en) 2019-10-03
EP4438128A2 (en) 2024-10-02
CA2969707A1 (en) 2016-06-09
IL252613A0 (en) 2017-07-31
GB201902819D0 (en) 2019-04-17
NZ733433A (en) 2019-08-30
US20220241464A1 (en) 2022-08-04
US20180154043A1 (en) 2018-06-07
GB201710646D0 (en) 2017-08-16
KR20180136588A (ko) 2018-12-24
AU2015355187C1 (en) 2020-02-20
US20190046691A1 (en) 2019-02-14
AU2015355187A1 (en) 2017-06-29
SG10201914058QA (en) 2020-03-30
US11596714B2 (en) 2023-03-07
KR20210043024A (ko) 2021-04-20
SG11201704502RA (en) 2017-06-29
GB2569056B (en) 2020-01-01
CN107250348A (zh) 2017-10-13
IL252613B (en) 2021-12-01
EP4438128A3 (en) 2024-11-13
US12465669B2 (en) 2025-11-11
WO2016089825A1 (en) 2016-06-09
CA2969707C (en) 2019-08-20
US20160151540A1 (en) 2016-06-02
US11266765B2 (en) 2022-03-08
EP3227431A1 (en) 2017-10-11
KR20190111167A (ko) 2019-10-01
EP3227431C0 (en) 2025-01-29
PH12017501009B1 (en) 2022-01-21
JP2020182880A (ja) 2020-11-12
US20230181797A1 (en) 2023-06-15
IL287488B2 (en) 2023-06-01
EA201791125A1 (ru) 2018-06-29
AU2019240603B2 (en) 2023-02-09
MY184931A (en) 2021-04-30
HK1245327A1 (zh) 2018-08-24
US20210322643A1 (en) 2021-10-21
HK1250515A1 (zh) 2018-12-21
US11000629B2 (en) 2021-05-11
KR20170098844A (ko) 2017-08-30
NZ755260A (en) 2021-12-24
US20180154044A1 (en) 2018-06-07
GB2549872A (en) 2017-11-01
JP2017538411A (ja) 2017-12-28
GB2569056A (en) 2019-06-05
BR112017011808A2 (pt) 2018-02-27
CN107250348B (zh) 2021-09-03
JP2019088299A (ja) 2019-06-13
EP3227431B1 (en) 2025-01-29
PH12017501009A1 (en) 2017-12-11
US11338060B2 (en) 2022-05-24
KR20180136587A (ko) 2018-12-24

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