MX2015014512A - PHARMACEUTICAL COMPOSITION, METHODS FOR TREATMENT AND ITS USES. - Google Patents

PHARMACEUTICAL COMPOSITION, METHODS FOR TREATMENT AND ITS USES.

Info

Publication number
MX2015014512A
MX2015014512A MX2015014512A MX2015014512A MX2015014512A MX 2015014512 A MX2015014512 A MX 2015014512A MX 2015014512 A MX2015014512 A MX 2015014512A MX 2015014512 A MX2015014512 A MX 2015014512A MX 2015014512 A MX2015014512 A MX 2015014512A
Authority
MX
Mexico
Prior art keywords
treating
methods
pharmaceutical composition
patients
type
Prior art date
Application number
MX2015014512A
Other languages
English (en)
Inventor
Hans-Juergen Woerle
Odd-Erik Johansen
Maximilian Von Eynatten
Eric Williams Mayoux
Uli Christian Broedl
David Cherney
Nima Soleymanlou
Bruce A Perkins
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US201361813223P priority Critical
Priority to US201361823045P priority
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Priority to PCT/EP2014/057754 priority patent/WO2014170383A1/en
Publication of MX2015014512A publication Critical patent/MX2015014512A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • A61K31/522Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

La presente invención también se refiere a determinados inhibidores de SGLT-2 para tratar, prevenir, retrasar y/o brindar protección contra la progresión de la enfermedad renal crónica en pacientes, por ejemplo, pacientes con prediabetes, diabetes mellitus tipo 1 o tipo 2.The present invention also relates to certain SGLT-2 inhibitors for treating, preventing, delaying and / or providing protection against the progression of chronic kidney disease in patients, for example, patients with prediabetes, type 1 or type 2 diabetes mellitus.
MX2015014512A 2013-04-18 2014-04-16 PHARMACEUTICAL COMPOSITION, METHODS FOR TREATMENT AND ITS USES. MX2015014512A (es)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US201361813223P true 2013-04-18 2013-04-18
US201361823045P true 2013-05-14 2013-05-14
PCT/EP2014/057754 WO2014170383A1 (en) 2013-04-18 2014-04-16 Pharmaceutical composition, methods for treating and uses thereof

Publications (1)

Publication Number Publication Date
MX2015014512A true MX2015014512A (es) 2016-02-09

Family

ID=50543578

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015014512A MX2015014512A (es) 2013-04-18 2014-04-16 PHARMACEUTICAL COMPOSITION, METHODS FOR TREATMENT AND ITS USES.

Country Status (13)

Country Link
US (6) US20140315832A1 (es)
EP (1) EP2986304A1 (es)
JP (2) JP2016520564A (es)
KR (1) KR20150144781A (es)
CN (1) CN105377266A (es)
AU (2) AU2014255727B2 (es)
CA (1) CA2909728A1 (es)
CL (1) CL2015003022A1 (es)
EA (1) EA033286B1 (es)
HK (1) HK1215378A1 (es)
MX (1) MX2015014512A (es)
PH (1) PH12015502310A1 (es)
WO (1) WO2014170383A1 (es)

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US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
US7772191B2 (en) 2005-05-10 2010-08-10 Boehringer Ingelheim International Gmbh Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein
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CN102838599A (zh) 2006-05-04 2012-12-26 贝林格尔.英格海姆国际有限公司 多晶型
PE20091730A1 (es) 2008-04-03 2009-12-10 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
KR20190016601A (ko) 2008-08-06 2019-02-18 베링거 인겔하임 인터내셔날 게엠베하 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
PE20120017A1 (es) 2009-02-13 2012-02-12 Boehringer Ingelheim Int PHARMACEUTICAL COMPOSITION INCLUDING A SGLT2 INHIBITOR, OPTIONALLY A DPP-IV INHIBITOR, AN ADDITIONAL ANTIDIABETIC AGENT, AND THEIR USES
SI2486029T1 (sl) 2009-09-30 2015-10-30 Boehringer Ingelheim International Gmbh Methods for the preparation of glucopyranosyl substituted benzyl-benzene derivatives
US10610489B2 (en) 2009-10-02 2020-04-07 Boehringer Ingelheim International Gmbh Pharmaceutical composition, pharmaceutical dosage form, process for their preparation, methods for treating and uses thereof
KR20120107080A (ko) 2009-11-27 2012-09-28 베링거 인겔하임 인터내셔날 게엠베하 리나글립틴과 같은 dpp-iv 억제제를 사용한 유전자형 검사된 당뇨병 환자의 치료
JP6034781B2 (ja) 2010-05-05 2016-11-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Combination therapy
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US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
US9192617B2 (en) 2012-03-20 2015-11-24 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
US20130303462A1 (en) 2012-05-14 2013-11-14 Boehringer Ingelheim International Gmbh Use of a dpp-4 inhibitor in podocytes related disorders and/or nephrotic syndrome
US20140303097A1 (en) 2013-04-05 2014-10-09 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
TR201901110T4 (tr) 2013-04-05 2019-02-21 Boehringer Ingelheim Int Empagliflozinin terapötik kullanımları.
WO2015101916A1 (en) 2013-12-30 2015-07-09 Mylan Laboratories Ltd. Process for the preparation of empagliflozin
US10285973B2 (en) 2014-11-10 2019-05-14 Merck Sharp & Dohme Corp. SGLT-2 inhibitors for treating metabolic disorders in patients with renal impairment or chronic kidney disease
WO2016174155A1 (en) * 2015-04-30 2016-11-03 Boehringer Ingelheim International Gmbh Methods and pharmaceutical compositions comprising a sglt2 inhibitor for treating or improving erectile dysfunction
CN109069525A (zh) * 2016-03-16 2018-12-21 勃林格殷格翰国际有限公司 包含依帕列净的药物组合物及其用途
BR112018072401A2 (pt) 2016-06-10 2019-02-19 Boehringer Ingelheim Int combinações de linagliptina e metformina
WO2018058109A1 (en) * 2016-09-26 2018-03-29 Nusirt Sciences, Inc. Compositions and methods for treating metabolic disorders
CA3039745A1 (en) * 2016-11-10 2018-05-17 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
WO2018096164A1 (en) * 2016-11-28 2018-05-31 Novo Nordisk A/S Insulin degludec for treating diabetes
WO2019244171A1 (en) * 2018-06-20 2019-12-26 Alkem Laboratories Ltd. Stable oral pharmaceutical composition of amorphous empagliflozin and process for preparing thereof
CN109846898A (zh) * 2019-02-01 2019-06-07 同济大学 恩格列净在制备治疗和/或预防心肌梗死的药物中的应用

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AR051446A1 (es) 2004-09-23 2007-01-17 Squibb Bristol Myers Co Glucosidos de c-arilo como inhibidores selectivos de transportadores de glucosa (sglt2)
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US10610489B2 (en) * 2009-10-02 2020-04-07 Boehringer Ingelheim International Gmbh Pharmaceutical composition, pharmaceutical dosage form, process for their preparation, methods for treating and uses thereof
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Also Published As

Publication number Publication date
JP2018027978A (ja) 2018-02-22
AU2019253791A1 (en) 2019-11-14
CA2909728A1 (en) 2014-10-23
US20190134072A1 (en) 2019-05-09
AU2014255727B2 (en) 2019-07-25
EA201501032A1 (ru) 2016-05-31
JP2016520564A (ja) 2016-07-14
US20140315832A1 (en) 2014-10-23
US20200138844A1 (en) 2020-05-07
US20180169126A1 (en) 2018-06-21
WO2014170383A1 (en) 2014-10-23
JP6574231B2 (ja) 2019-09-11
KR20150144781A (ko) 2015-12-28
US20160038525A1 (en) 2016-02-11
US20170333465A1 (en) 2017-11-23
CL2015003022A1 (es) 2016-06-17
EP2986304A1 (en) 2016-02-24
PH12015502310A1 (en) 2016-02-10
CN105377266A (zh) 2016-03-02
AU2014255727A1 (en) 2015-10-01
HK1215378A1 (zh) 2016-08-26
EA033286B1 (ru) 2019-09-30

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