MX2014011115A - Inhibidores de 3,5-diaminopirazol cinasa. - Google Patents

Inhibidores de 3,5-diaminopirazol cinasa.

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Publication number
MX2014011115A
MX2014011115A MX2014011115A MX2014011115A MX2014011115A MX 2014011115 A MX2014011115 A MX 2014011115A MX 2014011115 A MX2014011115 A MX 2014011115A MX 2014011115 A MX2014011115 A MX 2014011115A MX 2014011115 A MX2014011115 A MX 2014011115A
Authority
MX
Mexico
Prior art keywords
kinase inhibitors
diaminopyrazole
diaminopyrazole kinase
kinase
diaminopyrazoles
Prior art date
Application number
MX2014011115A
Other languages
English (en)
Inventor
Erik Dean Raaum
Garrett Thomas Potter
Tai Wei Ly
Original Assignee
Axikin Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axikin Pharmaceuticals Inc filed Critical Axikin Pharmaceuticals Inc
Publication of MX2014011115A publication Critical patent/MX2014011115A/es

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    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds

Abstract

En la presente se proporcionan los 3,5-diaminopirazoles, por ejemplo, compuestos que tienen la fórmula lA, útiles para modular la actividad de la regulada-en--COPD cinasa (RC cinasa), y las composiciones farmacéuticas de estos. También se proporcionan los métodos para su uso en el tratamiento, prevención o mejoría de uno o más síntomas de un trastorno, enfermedad o estado en los que interviene la RC cinasa.
MX2014011115A 2012-03-16 2013-03-14 Inhibidores de 3,5-diaminopirazol cinasa. MX2014011115A (es)

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