MX2014009172A - Terapia de combinacion que comprende hemifumarato de tenofovir alafenamida y cobicistat para el uso en el tratamiento de infecciones virales. - Google Patents
Terapia de combinacion que comprende hemifumarato de tenofovir alafenamida y cobicistat para el uso en el tratamiento de infecciones virales.Info
- Publication number
- MX2014009172A MX2014009172A MX2014009172A MX2014009172A MX2014009172A MX 2014009172 A MX2014009172 A MX 2014009172A MX 2014009172 A MX2014009172 A MX 2014009172A MX 2014009172 A MX2014009172 A MX 2014009172A MX 2014009172 A MX2014009172 A MX 2014009172A
- Authority
- MX
- Mexico
- Prior art keywords
- cobicistat
- tenofovir alafenamide
- pharmaceutically acceptable
- alafenamide hemifumarate
- acceptable salt
- Prior art date
Links
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| CN110343135A (zh) † | 2011-08-16 | 2019-10-18 | 吉利德科学公司 | 替诺福韦艾拉酚胺(tenofovir alafenamide)半反丁烯二酸盐 |
| CN103665043B (zh) | 2012-08-30 | 2017-11-10 | 江苏豪森药业集团有限公司 | 一种替诺福韦前药及其在医药上的应用 |
| HK1220390A1 (zh) * | 2013-08-29 | 2017-05-05 | Teva Pharmaceutical Industries Ltd. | 包括恩曲他滨，替诺福韦，达芦那韦和利托那韦的单位剂型以及包含达芦那韦和利托那韦的单体片剂 |
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| EP3129009A1 (en) * | 2014-04-08 | 2017-02-15 | Teva Pharmaceutical Industries Ltd | Unit dosage form comprising emtricitabine, tenofovir, darunavir and ritonavir |
| WO2015161781A1 (zh) * | 2014-04-21 | 2015-10-29 | 四川海思科制药有限公司 | 一种核苷类似物及其中间体的制备方法 |
| US10076512B2 (en) | 2014-05-01 | 2018-09-18 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
| US11311519B2 (en) | 2014-05-01 | 2022-04-26 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
| TWI733652B (zh) * | 2014-07-11 | 2021-07-21 | 美商基利科學股份有限公司 | 用於治療ＨＩＶ之ｔｏｌｌ樣受體調節劑 |
| JP2017526730A (ja) | 2014-09-16 | 2017-09-14 | ギリアード サイエンシーズ， インコーポレイテッド | Ｔｏｌｌ様受容体モジュレーターの固体形態 |
| CN105237571B (zh) * | 2014-11-28 | 2018-03-09 | 成都苑东生物制药股份有限公司 | 9‑[(r)‑2‑[[(s)‑[[(s)‑1‑(异丙氧基羰基)乙基]氨基]苯氧基氧膦基]甲氧基]丙基]腺嘌呤的盐 |
| EP3226973A4 (en) * | 2014-12-04 | 2018-05-30 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
| IL296496B2 (en) | 2014-12-26 | 2024-10-01 | Univ Emory | N4-hydroxycytidine and derivatives and anti-viral uses related thereto |
| EP3240793A1 (en) * | 2015-01-03 | 2017-11-08 | Mylan Laboratories Ltd. | Processes for the preparation of amorphous tenofovir alafenamide hemifumarate and a premix thereof |
| US10835496B2 (en) | 2015-04-21 | 2020-11-17 | Eiger Biopharmaceuticals, Inc. | Pharmaceutical compositions comprising lonafarnib and ritonavir |
| CN104817593B (zh) * | 2015-04-27 | 2016-11-16 | 广州同隽医药科技有限公司 | 半富马酸替诺福韦艾拉酚胺关键中间体的合成工艺 |
| CA2921336A1 (en) * | 2015-06-30 | 2016-12-30 | Gilead Sciences, Inc. | Pharmaceutical formulations |
| EA201792592A1 (ru) * | 2015-06-30 | 2018-06-29 | Джилид Сайэнс, Инк. | Фармацевтические препараты, содержащие тенофовир и эмтрицитабин |
| US9598459B2 (en) | 2015-08-03 | 2017-03-21 | Pop Test Oncology Llc | Pharmaceutical compositions and methods |
| CN105153231A (zh) * | 2015-08-28 | 2015-12-16 | 浙江车头制药股份有限公司 | 一种一苯基pmpa的制备方法 |
| SI3346995T1 (sl) * | 2015-11-09 | 2019-11-29 | Gilead Sciences Inc | Terapevtski sestavek za zdravljenje virusa človeške imunske pomanjkljivosti |
| EP3413913B1 (en) * | 2016-02-12 | 2021-11-24 | Cipla Limited | Pharmaceutical compositions comprising an anti-retroviral drug and a pharmacokinetic enhancer |
| CN107179355B (zh) * | 2016-03-11 | 2021-08-10 | 广东东阳光药业有限公司 | 一种分离检测替诺福韦艾拉酚胺及其有关物质的方法 |
| EP3503895B1 (en) * | 2016-08-25 | 2021-09-15 | Merck Sharp & Dohme Corp. | Antiviral prodrugs of tenofovir |
| CN108070003A (zh) * | 2016-12-02 | 2018-05-25 | 上海博志研新药物技术有限公司 | 替诺福韦艾拉酚胺半反丁烯二酸盐晶型及制备方法和应用 |
| RU2659388C1 (ru) | 2017-02-28 | 2018-07-02 | Васильевич Иващенко Александр | Нуклеотиды, включающие N-[(S)-1-циклобутоксикарбонил]фосфорамидатный фрагмент, их аналоги и их применение |
| RU2647576C1 (ru) * | 2017-02-28 | 2018-03-16 | Васильевич Иващенко Александр | Циклобутил (S)-2-[[[(R)-2-(6-аминопурин-9-ил)-1-метил-этокси]метил-фенокси-фосфорил]амино]-пропаноаты, способ их получения и применения |
| CN106928277A (zh) * | 2017-03-16 | 2017-07-07 | 江苏诚信药业有限公司 | 一种替诺福韦艾拉酚胺合成的工艺方法 |
| EP3600332B1 (en) | 2017-03-20 | 2023-12-13 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Hiv post-exposure prophylaxis |
| AU2018255954B2 (en) * | 2017-04-18 | 2024-04-04 | Cipla Limited | Combination therapy for use in treating retroviral infections |
| RU2659693C1 (ru) * | 2017-06-30 | 2018-07-03 | Общество с ограниченной ответственностью "Изварино Фарма" | Фармацевтическая композиция, обладающая активностью против ВИЧ-инфекции |
| US20190151307A1 (en) * | 2017-10-24 | 2019-05-23 | Gilead Sciences, Inc. | Methods of treating patients co-infected with a virus and tuberculosis |
| KR102626210B1 (ko) | 2017-12-07 | 2024-01-18 | 에모리 유니버시티 | N4-하이드록시사이티딘 및 유도체 및 이와 관련된 항-바이러스 용도 |
| CN110305163A (zh) * | 2018-03-27 | 2019-10-08 | 北京济美堂医药研究有限公司 | 替诺福韦艾拉酚胺半富马酸盐的制备方法 |
| CN108484672A (zh) * | 2018-05-23 | 2018-09-04 | 中国药科大学制药有限公司 | 磷丙替诺福韦的手性拆分方法 |
| CN109081853A (zh) * | 2018-09-03 | 2018-12-25 | 南京正大天晴制药有限公司 | 一种磷丙替诺福韦有关物质的制备方法 |
| KR20220011685A (ko) | 2019-05-22 | 2022-01-28 | 길리애드 사이언시즈, 인코포레이티드 | Tlr7 조절 화합물과 hiv 백신의 조합 |
| WO2020258211A1 (en) * | 2019-06-28 | 2020-12-30 | Anhui Ronghang Biotech Development Co., Ltd. | Compositions and methods for treatment of hepatitis b virus infection |
| CA3146263A1 (en) | 2019-07-19 | 2021-01-28 | Jose Gerardo Garcia Lerma | Hiv pre-exposure prophylaxis |
| CN111606949A (zh) * | 2020-03-13 | 2020-09-01 | 浙江车头制药股份有限公司 | 一种磷丙替诺福韦杂质的制备方法 |
| CN111303209A (zh) * | 2020-03-21 | 2020-06-19 | 石家庄龙泽制药股份有限公司 | 一种丙酚替诺福韦降解杂质的制备方法 |
| US20240009214A1 (en) * | 2020-12-02 | 2024-01-11 | Cipla Limited | Method of Treating Viral Infection |
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| EP4640214A1 (en) * | 2024-03-28 | 2025-10-29 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | A tablet comprising tenofovir alafenamide monofumarate |
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| DE10153078A1 (de) | 2001-10-30 | 2003-05-22 | Degussa | Verwendung von Granulaten auf Basis von pyrogen hergestelltem Siliciumdioxid in pharmazeutischen Zusammensetzungen |
| EA015145B1 (ru) | 2003-01-14 | 2011-06-30 | Джилид Сайэнс, Инк. | Фармацевтическая композиция и пероральная фармацевтическая дозированная форма (варианты), проявляющие активность в отношении вич-инфекций, лечебный набор и таблетка и способ лечения или предотвращения симптомов или эффектов вич-инфекции |
| EP4403221A3 (en) * | 2007-02-23 | 2024-10-09 | Gilead Sciences, Inc. | Modulators of pharmacokinetic properties of therapeutics |
| KR20100041798A (ko) | 2007-06-29 | 2010-04-22 | 한국화학연구원 | 신규 ｈｉｖ 역전사효소 억제제 |
| CN102307573B (zh) * | 2009-02-06 | 2013-09-11 | 吉里德科学公司 | 用于联合治疗的片剂 |
| CN110343135A (zh) * | 2011-08-16 | 2019-10-18 | 吉利德科学公司 | 替诺福韦艾拉酚胺(tenofovir alafenamide)半反丁烯二酸盐 |
-
2013
- 2013-02-01 MD MDA20140091A patent/MD20140091A2/ro not_active Application Discontinuation
- 2013-02-01 JP JP2014555783A patent/JP6059255B2/ja active Active
- 2013-02-01 HK HK15103394.9A patent/HK1202801A1/xx unknown
- 2013-02-01 CN CN201380007670.XA patent/CN104105484A/zh active Pending
- 2013-02-01 KR KR20147024291A patent/KR20140119177A/ko not_active Withdrawn
- 2013-02-01 BR BR112014018918A patent/BR112014018918A8/pt not_active IP Right Cessation
- 2013-02-01 WO PCT/US2013/024451 patent/WO2013116730A1/en not_active Ceased
- 2013-02-01 HK HK15105031.3A patent/HK1204914A1/xx unknown
- 2013-02-01 CA CA 2863662 patent/CA2863662A1/en not_active Abandoned
- 2013-02-01 MX MX2014009172A patent/MX2014009172A/es unknown
- 2013-02-01 NZ NZ629896A patent/NZ629896A/en unknown
- 2013-02-01 AU AU2013204727A patent/AU2013204727A1/en not_active Abandoned
- 2013-02-01 WO PCT/US2013/024438 patent/WO2013116720A1/en not_active Ceased
- 2013-02-01 EA EA201491287A patent/EA026138B1/ru unknown
- 2013-02-01 AU AU2013204731A patent/AU2013204731C1/en active Active
- 2013-02-01 EP EP13704863.3A patent/EP2809323A1/en not_active Withdrawn
- 2013-02-01 US US14/376,116 patent/US20150105350A1/en not_active Abandoned
-
2014
- 2014-07-30 IL IL233874A patent/IL233874A0/en unknown
-
2016
- 2016-06-02 AU AU2016203666A patent/AU2016203666A1/en not_active Abandoned
- 2016-10-03 US US15/284,105 patent/US20170056423A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20150105350A1 (en) | 2015-04-16 |
| EA201491287A1 (ru) | 2015-04-30 |
| MD20140091A2 (ro) | 2015-01-31 |
| US20170056423A1 (en) | 2017-03-02 |
| JP6059255B2 (ja) | 2017-01-11 |
| IL233874A0 (en) | 2014-09-30 |
| WO2013116730A1 (en) | 2013-08-08 |
| AU2013204727A1 (en) | 2013-08-22 |
| EP2809323A1 (en) | 2014-12-10 |
| AU2013204731B2 (en) | 2016-03-03 |
| BR112014018918A8 (pt) | 2017-07-11 |
| BR112014018918A2 (enExample) | 2017-06-20 |
| AU2013204731C1 (en) | 2017-08-31 |
| JP2015505565A (ja) | 2015-02-23 |
| WO2013116720A1 (en) | 2013-08-08 |
| AU2016203666A1 (en) | 2016-06-23 |
| HK1204914A1 (en) | 2015-12-11 |
| HK1202801A1 (en) | 2015-10-09 |
| KR20140119177A (ko) | 2014-10-08 |
| CN104105484A (zh) | 2014-10-15 |
| CA2863662A1 (en) | 2013-08-08 |
| NZ629896A (en) | 2016-03-31 |
| AU2013204731A1 (en) | 2013-08-22 |
| EA026138B1 (ru) | 2017-03-31 |
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