MX2012007210A - Implante removible degradable para la liberacion sostenida de un compuesto activo. - Google Patents

Implante removible degradable para la liberacion sostenida de un compuesto activo.

Info

Publication number
MX2012007210A
MX2012007210A MX2012007210A MX2012007210A MX2012007210A MX 2012007210 A MX2012007210 A MX 2012007210A MX 2012007210 A MX2012007210 A MX 2012007210A MX 2012007210 A MX2012007210 A MX 2012007210A MX 2012007210 A MX2012007210 A MX 2012007210A
Authority
MX
Mexico
Prior art keywords
sustained release
active compound
degradable
removable implant
microparticles
Prior art date
Application number
MX2012007210A
Other languages
English (en)
Spanish (es)
Inventor
Qiang Zhang
Guenter Kraus
Lieven Elvier Colette Baert
Deborah M Schachter
Iksoo Chun
Original Assignee
Janssen R & D Ireland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen R & D Ireland filed Critical Janssen R & D Ireland
Publication of MX2012007210A publication Critical patent/MX2012007210A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/146Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148Materials at least partially resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Nanotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • AIDS & HIV (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MX2012007210A 2009-12-21 2010-12-20 Implante removible degradable para la liberacion sostenida de un compuesto activo. MX2012007210A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28837309P 2009-12-21 2009-12-21
PCT/EP2010/070246 WO2011080141A2 (en) 2009-12-21 2010-12-20 Degradable removable implant for the sustained release of an active compound

Publications (1)

Publication Number Publication Date
MX2012007210A true MX2012007210A (es) 2012-07-23

Family

ID=43743502

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012007210A MX2012007210A (es) 2009-12-21 2010-12-20 Implante removible degradable para la liberacion sostenida de un compuesto activo.

Country Status (18)

Country Link
US (3) US8784858B2 (show.php)
EP (1) EP2515877B1 (show.php)
JP (1) JP5950825B2 (show.php)
KR (1) KR101798430B1 (show.php)
CN (1) CN102740837B (show.php)
AU (1) AU2010338425B2 (show.php)
BR (1) BR112012015114B1 (show.php)
CA (1) CA2784530C (show.php)
ES (1) ES2600878T3 (show.php)
IL (1) IL219685B (show.php)
MX (1) MX2012007210A (show.php)
MY (1) MY163383A (show.php)
NZ (1) NZ600156A (show.php)
RU (1) RU2593790C2 (show.php)
SG (1) SG181759A1 (show.php)
UA (1) UA112155C2 (show.php)
WO (1) WO2011080141A2 (show.php)
ZA (1) ZA201204583B (show.php)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2916425A1 (en) * 2013-06-20 2014-12-24 Mercy Medical Research Institute Extended release drug-delivery contact lenses and methods of making
AU2015301432B2 (en) 2014-08-15 2019-11-21 The Johns Hopkins University Composite material for tissue restoration
WO2016149561A1 (en) * 2015-03-17 2016-09-22 Oak Crest Institute Of Science Subdermal implants for the sustained delivery of water-soluble drugs
US11779435B2 (en) 2015-08-26 2023-10-10 Flexscrewdriver I.K.E. Dental screwdriver
CN106702597B (zh) * 2016-12-20 2019-06-18 华南理工大学 一种核-壳结构纳米纤维膜及其制备方法和应用
MX2020000376A (es) 2017-07-11 2020-07-14 Sustained Nano Systems Llc Formulaciones farmaceuticas hipercomprimidas.
IL278525B2 (en) 2018-05-09 2024-04-01 Univ Johns Hopkins Nanofiber-hydrogel composites for enhanced soft tissue replacement and regeneration
WO2019217765A1 (en) 2018-05-09 2019-11-14 The Johns Hopkins University Nanofiber-hydrogel composites for cell and tissue delivery
EP3793537A1 (en) * 2018-05-16 2021-03-24 Spirox, Inc. Allergic rhinitis drug delivery implant
CN113260350A (zh) 2018-10-16 2021-08-13 三角研究所 皮下可生物降解储器装置
IL297145A (en) * 2020-04-07 2022-12-01 Res Triangle Inst Multidrug compositions for a biodegradable subcutaneous reservoir device
EP4151673A4 (en) * 2020-05-12 2024-03-20 Laboratorios Farmacéuticos Rovi, S.A. METHOD FOR THE PURIFICATION OF BIODEGRADABLE THERMOPLASTIC POLYMER PARTICLES FOR MEDICAL AND/OR PHARMACEUTICAL USE

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5182111A (en) * 1987-11-17 1993-01-26 Boston University Research Foundation In vivo delivery of active factors by co-cultured cell implants
WO1993009176A2 (en) * 1991-10-29 1993-05-13 Clover Consolidated, Limited Crosslinkable polysaccharides, polycations and lipids useful for encapsulation and drug release
US5645684A (en) 1994-03-07 1997-07-08 The Regents Of The University Of California Multilayer high vertical aspect ratio thin film structures
US5660680A (en) 1994-03-07 1997-08-26 The Regents Of The University Of California Method for fabrication of high vertical aspect ratio thin film structures
JPH09512250A (ja) * 1994-03-07 1997-12-09 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 細胞移植体の隔離に用いる微小加工カプセル
US5798042A (en) 1994-03-07 1998-08-25 Regents Of The University Of California Microfabricated filter with specially constructed channel walls, and containment well and capsule constructed with such filters
US5651900A (en) 1994-03-07 1997-07-29 The Regents Of The University Of California Microfabricated particle filter
CN1378445B (zh) 1999-08-06 2013-02-06 得克萨斯系统大学评议会 药物释放生物可降解纤维植入物
US7033603B2 (en) 1999-08-06 2006-04-25 Board Of Regents The University Of Texas Drug releasing biodegradable fiber for delivery of therapeutics
KR100792391B1 (ko) 1999-10-06 2008-01-08 티보텍 파마슈티칼즈 리미티드 레트로바이러스 프로테아제 저해제로서의헥사하이드로푸로[2,3-b]푸란-3-일-N-[3-[(1,3-벤조디옥솔-5-일설포닐)(이소부틸)아미노]-1-벤질-2-하이드록시프로필]카바메이트
TWI284048B (en) 2000-01-27 2007-07-21 Zentaris Ag Compressed microparticles for dry injection
US20040115268A1 (en) 2000-04-26 2004-06-17 Control Delivery Systems, Inc. Systemic delivery of antiviral agents
DE10050199A1 (de) * 2000-10-11 2002-04-25 Ethicon Gmbh Flächiges Implantat mit im Ultraschall detektierbaren Elementen
WO2002092054A2 (en) * 2001-05-11 2002-11-21 Ortho-Mcneil Pharmaceutical, Inc. Immune modulation device for use in animals
MY169670A (en) 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
US7497855B2 (en) 2002-09-04 2009-03-03 Microchips, Inc. Method and device for the controlled delivery of parathyroid hormone
US20040156878A1 (en) * 2003-02-11 2004-08-12 Alireza Rezania Implantable medical device seeded with mammalian cells and methods of treatment
TWI457136B (zh) * 2005-04-04 2014-10-21 Tibotec Pharm Ltd Hiv-感染之預防
CA2603851A1 (en) 2005-04-11 2006-10-19 The Board Of Trustees Of The Leland Stanford Junior Unversity Multi-layer structure having a predetermined layer pattern including an agent
US20060252049A1 (en) 2005-05-04 2006-11-09 Shuler Richard O Growth-promoting and immunizing subcutaneous implant
US7261529B2 (en) 2005-09-07 2007-08-28 Southwest Research Institute Apparatus for preparing biodegradable microparticle formulations containing pharmaceutically active agents
AR059097A1 (es) * 2006-01-20 2008-03-12 Tibotec Pharm Ltd Tratamiento a largo plazo de la infeccion por vih
WO2008060360A2 (en) * 2006-09-28 2008-05-22 Surmodics, Inc. Implantable medical device with apertures for delivery of bioactive agents
ES2394952T3 (es) * 2007-06-12 2013-02-07 Concert Pharmaceuticals Inc. Derivados de axapéptido como inhibidores de la proteasa VIH
WO2009046299A2 (en) * 2007-10-04 2009-04-09 Boston Scientific Scimed, Inc Implantable drug depot for intrathecal drug delivery system for pain management
WO2010047819A1 (en) * 2008-10-24 2010-04-29 Concert Pharmaceuticals, Inc. Hydroxyethylamino sulfonamide derivatives
KR101726615B1 (ko) 2008-12-24 2017-04-13 얀센 사이언시즈 아일랜드 유씨 Hiv 치료용 체내 임플란트 장치

Also Published As

Publication number Publication date
NZ600156A (en) 2015-01-30
SG181759A1 (en) 2012-07-30
EP2515877A2 (en) 2012-10-31
WO2011080141A2 (en) 2011-07-07
IL219685A0 (en) 2012-07-31
US20200330654A1 (en) 2020-10-22
JP5950825B2 (ja) 2016-07-13
WO2011080141A3 (en) 2012-03-08
KR20120101084A (ko) 2012-09-12
BR112012015114A2 (pt) 2020-09-01
RU2593790C2 (ru) 2016-08-10
US11395867B2 (en) 2022-07-26
US20120277690A1 (en) 2012-11-01
US20140296799A1 (en) 2014-10-02
US10744235B2 (en) 2020-08-18
IL219685B (en) 2019-03-31
KR101798430B1 (ko) 2017-11-16
UA112155C2 (uk) 2016-08-10
RU2012131282A (ru) 2014-01-27
ZA201204583B (en) 2022-03-30
BR112012015114B1 (pt) 2023-01-10
CA2784530A1 (en) 2011-07-07
ES2600878T3 (es) 2017-02-13
CN102740837A (zh) 2012-10-17
EP2515877B1 (en) 2016-08-10
CN102740837B (zh) 2017-06-06
US8784858B2 (en) 2014-07-22
MY163383A (en) 2017-09-15
JP2013514971A (ja) 2013-05-02
AU2010338425A1 (en) 2012-06-07
AU2010338425B2 (en) 2015-07-23
CA2784530C (en) 2018-05-22

Similar Documents

Publication Publication Date Title
MY163383A (en) Degradable removable implant for the sustained release of an active compound
MX2015003665A (es) Microcapsulas biodegradables que contienen material de relleno.
WO2012034049A3 (en) Implantable medical devices having double walled microspheres
FR2949062B1 (fr) Nouvelles formulations pharmaceutiques contre le mesusage des medicaments
IL219395A0 (en) Biodegradable implantable medical devices formed from super-pure magnesium-based material
BRPI1014139A2 (pt) sistema de liberação de fármacos compreendendo polioxazolina e um agente biotivo.
NZ706725A (en) Drug-eluting self-retaining sutures and methods relating thereto
CY1119829T1 (el) Βιοαποικοδομησιμες συνθεσεις απελευθερωσης φαρμακου
CA2873879A1 (en) Vascular occlusion and drug delivery devices, systems, and methods
WO2009002641A3 (en) Nanobead releasing medical devices
CL2013000423A1 (es) Forma de dosificacion farmaceutica con resistencia a rompimiento de al menos 500 n, que contiene un ingrediente activo, un polisacarido anionico y un oxido de polialquileno, en donde el ingrediente activo esta presente en una matriz de liberacion controlada comprendiendo el polisacarido anionico y el oxido de polialquileno.
CR10349A (es) Tabletas de paracetamol de liberacion rapida
WO2008024511A3 (en) Medical devices for the release of therapeutic agents
WO2010099292A3 (en) Biodegradable drug or other active delivery system
PL2194784T3 (pl) Kombinacje substancji czynnych o właściwościach owadobójczych i roztoczobójczych
BR112012027794A2 (pt) tablete entérico
PA8802901A1 (es) Recubrimiento mejorado de tableta
WO2009107136A3 (en) Drug delivery device, system and method
JO3587B1 (ar) أشكال جرعات بينداموستين عن طريق الفم
WO2014060443A3 (en) A composite scaffold for use as a tissue engineering implant
BR112012027782A2 (pt) tablete entérico
EP2424556A4 (en) EXTENDED RELEASE FORMULATIONS OF PEPTIDOMIMETIC MEDICAMENTS AND USES THEREOF
GEP20115158B (en) Use of ivabradine for obtaining medicaments intended for the treatment of endothelial dysfunction
MX2021002459A (es) Formas de dosificacion en capsula disuasorias del abuso de liberacion inmediata.
EP2540324A3 (en) Biodegradable materials for orthopedic devices based on polymer stereocomplexes

Legal Events

Date Code Title Description
FG Grant or registration