UA112155C2 - Розкладаний видалюваний імплантат для безперервного вивільнення активної сполуки - Google Patents

Розкладаний видалюваний імплантат для безперервного вивільнення активної сполуки Download PDF

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Publication number
UA112155C2
UA112155C2 UAA201206035A UAA201206035A UA112155C2 UA 112155 C2 UA112155 C2 UA 112155C2 UA A201206035 A UAA201206035 A UA A201206035A UA A201206035 A UAA201206035 A UA A201206035A UA 112155 C2 UA112155 C2 UA 112155C2
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UA
Ukraine
Prior art keywords
microparticles
tube
polymer
complex
implant according
Prior art date
Application number
UAA201206035A
Other languages
English (en)
Ukrainian (uk)
Inventor
Дебора М. Шачтер
Лівен Ельвір Колетт Берт
Гюнтер Краус
Кьюанг Зханг
Іксоо Чін
Original Assignee
ЯНССЕН САЙЄНСІЗ АЙРЛЕНД ЮСі
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Application filed by ЯНССЕН САЙЄНСІЗ АЙРЛЕНД ЮСі filed Critical ЯНССЕН САЙЄНСІЗ АЙРЛЕНД ЮСі
Publication of UA112155C2 publication Critical patent/UA112155C2/uk

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/146Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148Materials at least partially resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Nanotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • AIDS & HIV (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
UAA201206035A 2009-12-21 2010-12-20 Розкладаний видалюваний імплантат для безперервного вивільнення активної сполуки UA112155C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28837309P 2009-12-21 2009-12-21
PCT/EP2010/070246 WO2011080141A2 (en) 2009-12-21 2010-12-20 Degradable removable implant for the sustained release of an active compound

Publications (1)

Publication Number Publication Date
UA112155C2 true UA112155C2 (uk) 2016-08-10

Family

ID=43743502

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201206035A UA112155C2 (uk) 2009-12-21 2010-12-20 Розкладаний видалюваний імплантат для безперервного вивільнення активної сполуки

Country Status (18)

Country Link
US (3) US8784858B2 (show.php)
EP (1) EP2515877B1 (show.php)
JP (1) JP5950825B2 (show.php)
KR (1) KR101798430B1 (show.php)
CN (1) CN102740837B (show.php)
AU (1) AU2010338425B2 (show.php)
BR (1) BR112012015114B1 (show.php)
CA (1) CA2784530C (show.php)
ES (1) ES2600878T3 (show.php)
IL (1) IL219685B (show.php)
MX (1) MX2012007210A (show.php)
MY (1) MY163383A (show.php)
NZ (1) NZ600156A (show.php)
RU (1) RU2593790C2 (show.php)
SG (1) SG181759A1 (show.php)
UA (1) UA112155C2 (show.php)
WO (1) WO2011080141A2 (show.php)
ZA (1) ZA201204583B (show.php)

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WO2016149561A1 (en) * 2015-03-17 2016-09-22 Oak Crest Institute Of Science Subdermal implants for the sustained delivery of water-soluble drugs
US11779435B2 (en) 2015-08-26 2023-10-10 Flexscrewdriver I.K.E. Dental screwdriver
CN106702597B (zh) * 2016-12-20 2019-06-18 华南理工大学 一种核-壳结构纳米纤维膜及其制备方法和应用
MX2020000376A (es) 2017-07-11 2020-07-14 Sustained Nano Systems Llc Formulaciones farmaceuticas hipercomprimidas.
IL278525B2 (en) 2018-05-09 2024-04-01 Univ Johns Hopkins Nanofiber-hydrogel composites for enhanced soft tissue replacement and regeneration
WO2019217765A1 (en) 2018-05-09 2019-11-14 The Johns Hopkins University Nanofiber-hydrogel composites for cell and tissue delivery
EP3793537A1 (en) * 2018-05-16 2021-03-24 Spirox, Inc. Allergic rhinitis drug delivery implant
CN113260350A (zh) 2018-10-16 2021-08-13 三角研究所 皮下可生物降解储器装置
IL297145A (en) * 2020-04-07 2022-12-01 Res Triangle Inst Multidrug compositions for a biodegradable subcutaneous reservoir device
EP4151673A4 (en) * 2020-05-12 2024-03-20 Laboratorios Farmacéuticos Rovi, S.A. METHOD FOR THE PURIFICATION OF BIODEGRADABLE THERMOPLASTIC POLYMER PARTICLES FOR MEDICAL AND/OR PHARMACEUTICAL USE

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Also Published As

Publication number Publication date
MX2012007210A (es) 2012-07-23
NZ600156A (en) 2015-01-30
SG181759A1 (en) 2012-07-30
EP2515877A2 (en) 2012-10-31
WO2011080141A2 (en) 2011-07-07
IL219685A0 (en) 2012-07-31
US20200330654A1 (en) 2020-10-22
JP5950825B2 (ja) 2016-07-13
WO2011080141A3 (en) 2012-03-08
KR20120101084A (ko) 2012-09-12
BR112012015114A2 (pt) 2020-09-01
RU2593790C2 (ru) 2016-08-10
US11395867B2 (en) 2022-07-26
US20120277690A1 (en) 2012-11-01
US20140296799A1 (en) 2014-10-02
US10744235B2 (en) 2020-08-18
IL219685B (en) 2019-03-31
KR101798430B1 (ko) 2017-11-16
RU2012131282A (ru) 2014-01-27
ZA201204583B (en) 2022-03-30
BR112012015114B1 (pt) 2023-01-10
CA2784530A1 (en) 2011-07-07
ES2600878T3 (es) 2017-02-13
CN102740837A (zh) 2012-10-17
EP2515877B1 (en) 2016-08-10
CN102740837B (zh) 2017-06-06
US8784858B2 (en) 2014-07-22
MY163383A (en) 2017-09-15
JP2013514971A (ja) 2013-05-02
AU2010338425A1 (en) 2012-06-07
AU2010338425B2 (en) 2015-07-23
CA2784530C (en) 2018-05-22

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