MC1882A1 - Composes anti-viraux - Google Patents
Composes anti-virauxInfo
- Publication number
- MC1882A1 MC1882A1 MC871936A MC1936A MC1882A1 MC 1882 A1 MC1882 A1 MC 1882A1 MC 871936 A MC871936 A MC 871936A MC 1936 A MC1936 A MC 1936A MC 1882 A1 MC1882 A1 MC 1882A1
- Authority
- MC
- Monaco
- Prior art keywords
- viral compounds
- cytomegalovirus
- prophylaxis
- pharmaceutically acceptable
- processes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Developing Agents For Electrophotography (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Silicon Polymers (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB868629892A GB8629892D0 (en) | 1986-12-15 | 1986-12-15 | Antiviral compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
MC1882A1 true MC1882A1 (fr) | 1989-01-24 |
Family
ID=10609013
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MC871936A MC1882A1 (fr) | 1986-12-15 | 1987-12-14 | Composes anti-viraux |
Country Status (30)
Country | Link |
---|---|
US (1) | US5079235A (de) |
EP (3) | EP0417560A1 (de) |
JP (2) | JPS63165397A (de) |
KR (1) | KR880007521A (de) |
CN (2) | CN87108265A (de) |
AT (1) | ATE88713T1 (de) |
AU (2) | AU601529B2 (de) |
CA (1) | CA1319143C (de) |
CS (3) | CS275398B2 (de) |
DD (2) | DD264924A5 (de) |
DE (1) | DE3785651T2 (de) |
DK (2) | DK654287A (de) |
ES (1) | ES2054693T3 (de) |
FI (2) | FI875487A (de) |
GB (1) | GB8629892D0 (de) |
HU (4) | HU207735B (de) |
IE (2) | IE930470L (de) |
IL (3) | IL84810A (de) |
LT (1) | LT2064B (de) |
LV (1) | LV5273A3 (de) |
MC (1) | MC1882A1 (de) |
MX (1) | MX9203216A (de) |
NO (1) | NO167576C (de) |
NZ (1) | NZ222898A (de) |
PH (2) | PH24104A (de) |
PL (3) | PL160322B1 (de) |
PT (1) | PT86356B (de) |
RU (1) | RU2036199C1 (de) |
SU (1) | SU1731064A3 (de) |
ZA (1) | ZA879382B (de) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1340032C (en) * | 1987-06-24 | 1998-09-08 | Jim Haralambidis | Lucleoside derivatives |
US4954485A (en) * | 1987-10-20 | 1990-09-04 | Sanyo-Kokusaku Pulp Co., Ltd. | 2',3'-dideoxy-4-thio-uridine derivatives, process for their preparation and antivirus agents using them |
EP0346108A3 (de) * | 1988-06-09 | 1991-04-24 | The Wellcome Foundation Limited | Anti-infektiöse Nukleoside |
US5157114A (en) * | 1988-08-19 | 1992-10-20 | Burroughs Wellcome Co. | 2',3'-dideoxy-3'-fluoro-5-ethyngluridine |
GB8827339D0 (en) * | 1988-11-23 | 1988-12-29 | Wellcome Found | Antiviral compounds |
US5006646A (en) * | 1989-02-22 | 1991-04-09 | Yuki Gosei Kogyo Co., Ltd. | Process for preparing 2'-deoxy-5-trifluoromethyl-beta-uridine |
IE902574A1 (en) * | 1989-07-17 | 1991-02-27 | Univ Birmingham | Antiviral pyrimidine nucleosides |
DD293498A5 (de) * | 1989-07-20 | 1991-09-05 | Zi Fuer Molekularbiologie Der Adw,De | Verfahren zur herstellung eines mittels fuer die behandlung oder prophylaxe von hepatits-infektionen bei mensch und tier |
US6337209B1 (en) | 1992-02-26 | 2002-01-08 | Glaxo Wellcome Inc. | Molecular constructs containing a carcinoembryonic antigen regulatory sequence |
GB8919607D0 (en) | 1989-08-30 | 1989-10-11 | Wellcome Found | Novel entities for cancer therapy |
GB9008696D0 (en) * | 1990-04-18 | 1990-06-13 | Wellcome Found | Anti-viral compounds |
GB9012899D0 (en) * | 1990-06-09 | 1990-08-01 | Wellcome Found | Anti-hbv pyrimidine nucleoside |
GB9014618D0 (en) * | 1990-06-30 | 1990-08-22 | Wellcome Found | Process for the preparation of pyrimidine nucleosides |
EP0711555A2 (de) * | 1990-07-19 | 1996-05-15 | The Wellcome Foundation Limited | Enzyminaktivatoren |
US5643913A (en) * | 1990-07-19 | 1997-07-01 | Glaxo Wellcome Inc. | Pharmaceutical compositions of 5-substituted uracil compounds |
GB9020930D0 (en) * | 1990-09-26 | 1990-11-07 | Wellcome Found | Pharmaceutical combinations |
GB9104165D0 (en) * | 1991-02-27 | 1991-04-17 | Wellcome Found | Novel entities for hiv therapy |
GB9111580D0 (en) * | 1991-05-30 | 1991-07-24 | Wellcome Found | Nucleoside derivative |
US5580858A (en) * | 1991-06-10 | 1996-12-03 | Alberta Research Council | Immunosuppressive and tolerogenic modified Lewisx compounds |
US5646123A (en) * | 1991-06-10 | 1997-07-08 | Alberta Research Council | Time dependent administration of oligosaccharide glycosides related to blood group determinants having a type I or type II core structure in reducing inflammation in a sensitized mammal arising form exposure to an antigen |
HU207524B (en) * | 1991-11-22 | 1993-04-28 | Mta Koezponti Kemiai Kutato In | Industrial process for producing 5-alkyl-2'-deoxy-beta-uridines with stereoselective synthesis |
DE637965T1 (de) * | 1991-11-26 | 1995-12-14 | Gilead Sciences Inc | Gesteigerte bildung von triple- und doppelhelices aus oligomeren mit modifizierten pyrimidinen. |
TW393513B (en) * | 1991-11-26 | 2000-06-11 | Isis Pharmaceuticals Inc | Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines |
US6235887B1 (en) | 1991-11-26 | 2001-05-22 | Isis Pharmaceuticals, Inc. | Enhanced triple-helix and double-helix formation directed by oligonucleotides containing modified pyrimidines |
US5484908A (en) * | 1991-11-26 | 1996-01-16 | Gilead Sciences, Inc. | Oligonucleotides containing 5-propynyl pyrimidines |
JP2823358B2 (ja) * | 1992-05-26 | 1998-11-11 | アルバータ リサーチ カウンスル | 免疫抑制性および寛容原性修飾ルイス▲上c▼およびLacNAc化合物 |
CA2119315A1 (en) * | 1993-03-18 | 1994-09-19 | Tsujiaki Hata | Nucleoside derivatives and anti-herpes composition |
US6432924B1 (en) | 1993-12-26 | 2002-08-13 | East Carolina University | Method of treating disorders characterized by overexpression of cytidine deaminase or deoxycytidine deaminase |
RU98113785A (ru) * | 1995-12-22 | 2000-06-10 | Ист Каролина Юниверсити (US) | Агент и способ лечения заболеваний, связанных с чрезмерной экспрессией цитидиндезаминазы или дезоксицитидинзаминазы |
WO1997027849A1 (fr) * | 1996-02-02 | 1997-08-07 | Showa Shell Sekiyu K.K. | Medicaments pour traiter les infections provoquees par le virus de l'herpes et compositions preventives pour empecher un retour de l'infection, contenant tous les deux des derives triterpeniques comme principe actif |
US6653318B1 (en) | 1999-07-21 | 2003-11-25 | Yale University | 5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use |
US7019129B1 (en) | 2000-05-09 | 2006-03-28 | Biosearch Technologies, Inc. | Dark quenchers for donor-acceptor energy transfer |
WO2003053360A2 (en) | 2001-12-20 | 2003-07-03 | Pharmassett Ltd. | Treatment of ebv and khsv infection and associated abnormal cellular proliferation |
WO2006060697A1 (en) | 2004-12-03 | 2006-06-08 | Adherex Technologies, Inc. | Methods for administering dpd inhibitors in combination with 5-fu and 5-fu prodrugs |
ES2633786T3 (es) | 2008-04-01 | 2017-09-25 | Biosearch Technologies, Inc. | Sondas de fluoróforo atenuadoras oscuras de ácido nucleico estabilizado |
CN101768197A (zh) * | 2008-12-29 | 2010-07-07 | 北京德众万全药物技术开发有限公司 | 一种奈拉滨的制备方法 |
EP2488182B1 (de) | 2009-10-14 | 2017-07-19 | Elion Oncology LLC | Behandlung von Neurotoxizität assoziert mit Kombinationen aus 5-FU oder Prodrugs davon und DPD-Hemmer |
JP6574240B2 (ja) * | 2014-03-30 | 2019-09-11 | セフィエド | 修飾シトシンポリヌクレオチドオリゴマーおよび方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1601020A (en) * | 1978-04-24 | 1981-10-21 | Stichting Grega Vzw | 2'-deoxy-5 (2-halogenovinyl)-uridines |
US4211773A (en) * | 1978-10-02 | 1980-07-08 | Sloan Kettering Institute For Cancer Research | 5-Substituted 1-(2'-Deoxy-2'-substituted-β-D-arabinofuranosyl)pyrimidine nucleosides |
US4267171A (en) * | 1979-07-02 | 1981-05-12 | The Regents Of The University Of California | C-5 Substituted cytosine nucleosides |
US4247544A (en) * | 1979-07-02 | 1981-01-27 | The Regents Of The University Of California | C-5 Substituted uracil nucleosides |
US4274544A (en) * | 1980-03-11 | 1981-06-23 | The Continental Group, Inc. | Single-piece plastic closure having integral seal forming means |
EP0082667A1 (de) * | 1981-12-18 | 1983-06-29 | Beecham Group Plc | Pharmazeutische Zusammensetzungen |
EP0082668A1 (de) * | 1981-12-18 | 1983-06-29 | Beecham Group Plc | 5-(2-Halogenvinyl)-2'-Deoxyuridinderivate, Verfahren zu ihrer Herstellung, die sie enthaltende pharmazeutische Präparate und ihre Verwendung bei der Bekämpfung von viralen Infektionen |
EP0095294A1 (de) * | 1982-05-22 | 1983-11-30 | Beecham Group Plc | Deoxyuridin-Derivate, ihre Herstellungsverfahren und ihre medizinische Anwendung |
EP0097039A1 (de) * | 1982-06-16 | 1983-12-28 | Beecham Group Plc | 5-(E-2-Halovinyl)-2'-deoxyuridin-Derivate, Verfahren zur Herstellung, sie enthaltende pharmazeutische Zusammensetzungen und ihre Anwendung bei der Behandlung von viralen Infektionen |
GB8517402D0 (en) * | 1985-07-10 | 1985-08-14 | Wellcome Found | Treatment of viral infections |
AU595832B2 (en) * | 1985-09-17 | 1990-04-12 | Wellcome Foundation Limited, The | Therapeutic nucleosides |
SE8701605D0 (sv) * | 1987-04-16 | 1987-04-16 | Astra Ab | Novel medicinal compounds |
-
1986
- 1986-12-15 GB GB868629892A patent/GB8629892D0/en active Pending
-
1987
- 1987-12-14 HU HU903829A patent/HU207735B/hu not_active IP Right Cessation
- 1987-12-14 PT PT86356A patent/PT86356B/pt not_active IP Right Cessation
- 1987-12-14 DD DD87310427A patent/DD264924A5/de not_active IP Right Cessation
- 1987-12-14 NO NO875209A patent/NO167576C/no unknown
- 1987-12-14 PL PL1987277927A patent/PL160322B1/pl unknown
- 1987-12-14 IE IE930470A patent/IE930470L/xx unknown
- 1987-12-14 JP JP62315960A patent/JPS63165397A/ja active Granted
- 1987-12-14 KR KR870014274A patent/KR880007521A/ko not_active Application Discontinuation
- 1987-12-14 AT AT87310951T patent/ATE88713T1/de not_active IP Right Cessation
- 1987-12-14 CS CS879161A patent/CS275398B2/cs unknown
- 1987-12-14 CS CS913425A patent/CS342591A3/cs unknown
- 1987-12-14 ZA ZA879382A patent/ZA879382B/xx unknown
- 1987-12-14 EP EP90116634A patent/EP0417560A1/de not_active Withdrawn
- 1987-12-14 CN CN198787108265A patent/CN87108265A/zh active Pending
- 1987-12-14 PH PH36211A patent/PH24104A/en unknown
- 1987-12-14 IL IL84810A patent/IL84810A/xx not_active IP Right Cessation
- 1987-12-14 PL PL1987269462A patent/PL158050B1/pl unknown
- 1987-12-14 SU SU874355176A patent/SU1731064A3/ru active
- 1987-12-14 IE IE930471A patent/IE930471L/xx unknown
- 1987-12-14 NZ NZ222898A patent/NZ222898A/en unknown
- 1987-12-14 CS CS877675A patent/CS275402B6/cs unknown
- 1987-12-14 HU HU893368A patent/HU200932B/hu not_active IP Right Cessation
- 1987-12-14 EP EP19920103712 patent/EP0486477A3/en not_active Withdrawn
- 1987-12-14 DE DE87310951T patent/DE3785651T2/de not_active Expired - Fee Related
- 1987-12-14 EP EP87310951A patent/EP0272065B1/de not_active Expired - Lifetime
- 1987-12-14 DD DD87320503A patent/DD274766A5/de not_active IP Right Cessation
- 1987-12-14 MC MC871936A patent/MC1882A1/xx unknown
- 1987-12-14 DK DK654287A patent/DK654287A/da not_active Application Discontinuation
- 1987-12-14 ES ES87310951T patent/ES2054693T3/es not_active Expired - Lifetime
- 1987-12-14 HU HU893367A patent/HU202112B/hu not_active IP Right Cessation
- 1987-12-14 CA CA000554258A patent/CA1319143C/en not_active Expired - Fee Related
- 1987-12-14 FI FI875487A patent/FI875487A/fi not_active Application Discontinuation
- 1987-12-14 AU AU82521/87A patent/AU601529B2/en not_active Ceased
- 1987-12-14 IL IL95141A patent/IL95141A/xx unknown
- 1987-12-14 HU HU875642A patent/HU199867B/hu not_active IP Right Cessation
- 1987-12-14 PL PL1987277926A patent/PL160321B1/pl unknown
-
1988
- 1988-07-05 PH PH37174A patent/PH24870A/en unknown
-
1989
- 1989-05-26 RU SU894614158A patent/RU2036199C1/ru active
-
1990
- 1990-01-16 US US07/465,552 patent/US5079235A/en not_active Expired - Lifetime
- 1990-07-20 IL IL95141A patent/IL95141A0/xx unknown
- 1990-07-26 AU AU59890/90A patent/AU626041B2/en not_active Ceased
- 1990-10-08 JP JP2270325A patent/JPH03141292A/ja active Pending
-
1991
- 1991-10-04 DK DK169991A patent/DK168323B1/da not_active IP Right Cessation
-
1992
- 1992-06-24 MX MX9203216A patent/MX9203216A/es unknown
- 1992-12-18 LV LV920338A patent/LV5273A3/xx unknown
- 1992-12-30 LT LTRP271A patent/LT2064B/xx unknown
-
1993
- 1993-02-27 CN CN93102155A patent/CN1080292A/zh active Pending
-
1994
- 1994-03-31 FI FI941523A patent/FI941523A/fi not_active Application Discontinuation
Also Published As
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Publication | Publication Date | Title |
---|---|---|
MC1882A1 (fr) | Composes anti-viraux | |
DE3679353D1 (de) | Antivirale verbindungen. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
YP | Annual fee paid |