MA30331B1 - ANTICORPS à EFGL 7 ET LEURS PROCEDES D'UTILISATION - Google Patents

ANTICORPS à EFGL 7 ET LEURS PROCEDES D'UTILISATION

Info

Publication number
MA30331B1
MA30331B1 MA31284A MA31284A MA30331B1 MA 30331 B1 MA30331 B1 MA 30331B1 MA 31284 A MA31284 A MA 31284A MA 31284 A MA31284 A MA 31284A MA 30331 B1 MA30331 B1 MA 30331B1
Authority
MA
Morocco
Prior art keywords
antibodies
methods
efgl
efgl7
relates
Prior art date
Application number
MA31284A
Other languages
English (en)
Inventor
Weilan Ye
Maike Schmidt
Jo-Anne Hongo
Yan Wu
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MA30331B1 publication Critical patent/MA30331B1/fr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507Comprising a combination of two or more separate antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne des anticorps anti-EFGL7, des compositions contenant de tels anticorps et les procédés d'utilisation de ces anticorps.
MA31284A 2006-03-16 2008-10-13 ANTICORPS à EFGL 7 ET LEURS PROCEDES D'UTILISATION MA30331B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78368606P 2006-03-16 2006-03-16
US81256906P 2006-06-09 2006-06-09

Publications (1)

Publication Number Publication Date
MA30331B1 true MA30331B1 (fr) 2009-04-01

Family

ID=38510306

Family Applications (1)

Application Number Title Priority Date Filing Date
MA31284A MA30331B1 (fr) 2006-03-16 2008-10-13 ANTICORPS à EFGL 7 ET LEURS PROCEDES D'UTILISATION

Country Status (20)

Country Link
US (3) US20100203041A1 (fr)
EP (2) EP1994056B1 (fr)
JP (2) JP5363972B2 (fr)
KR (1) KR101038633B1 (fr)
AR (1) AR059851A1 (fr)
AU (1) AU2007226522B2 (fr)
BR (1) BRPI0707047A2 (fr)
CA (1) CA2646513A1 (fr)
CO (1) CO6180454A2 (fr)
CR (1) CR10280A (fr)
EC (1) ECSP088743A (fr)
IL (3) IL193514A0 (fr)
MA (1) MA30331B1 (fr)
MX (1) MX2008011663A (fr)
NO (1) NO20084320L (fr)
NZ (2) NZ570588A (fr)
PH (1) PH12013502194A1 (fr)
RU (1) RU2415870C2 (fr)
TW (1) TW201446798A (fr)
WO (1) WO2007106915A2 (fr)

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Publication number Priority date Publication date Assignee Title
DE10113776B4 (de) * 2001-03-21 2012-08-09 "Iba Gmbh" Isoliertes streptavidinbindendes, kompetitiv eluierbares Peptid, dieses umfassendes Fusionspeptid, dafür codierende Nukleinsäure, Expressionsvektor, Verfahren zur Herstellung eines rekombinanten Fusionsproteins und Verfahren zum Nachweis und/oder zur Gewinnung des Fusionsproteins
AR059851A1 (es) * 2006-03-16 2008-04-30 Genentech Inc Anticuerpos de la egfl7 y metodos de uso
WO2010034155A1 (fr) * 2008-09-25 2010-04-01 中南大学湘雅医院 Kit de détection d’egfl7 dans des échantillons pour le diagnostic du carcinome hépatocellulaire et son application
RU2011149798A (ru) * 2009-05-08 2013-06-20 Дженентек, Инк. Гуманизированные анти-egfl7-антитела и способы их применения
TWI560199B (en) * 2010-08-31 2016-12-01 Sanofi Sa Peptide or peptide complex binding to α2 integrin and methods and uses involving the same
WO2012106473A2 (fr) * 2011-02-02 2012-08-09 Genentech, Inc. Dosage pour le traitement par des anticorps anti-egfl7
WO2013061112A1 (fr) 2011-10-24 2013-05-02 Centre National De La Recherche Scientifique Utilisation de modulateurs de egfl7 afin de favoriser ou d'inhiber la migration de cellules immunitaires à travers l'endothélium vasculaire
US9789213B2 (en) * 2012-03-27 2017-10-17 London Health Sciences Centre Research Inc. EGFL7 targeting and/or binding polypeptides and methods for inhibiting angiogenesis
WO2017136807A1 (fr) 2016-02-05 2017-08-10 The Board Of Regents Of The University Of Texas System Anticorps monoclonaux spécifiques de egfl6 et procédés pour les utiliser
EP3615075A4 (fr) * 2017-04-24 2021-01-20 Ohio State Innovation Foundation Egfl7 recombinant, anticorps anti-egfl7, et leurs utilisations
WO2025149667A1 (fr) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Conjugués anticorps-médicament et leurs utilisations

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CO6180454A2 (es) 2010-07-19
AU2007226522A1 (en) 2007-09-20
US8398976B2 (en) 2013-03-19
RU2415870C2 (ru) 2011-04-10
NZ570588A (en) 2011-11-25
KR101038633B1 (ko) 2011-06-03
PH12013502194A1 (en) 2015-02-09
CR10280A (es) 2008-11-07
ECSP088743A (es) 2008-10-31
IL232011A0 (en) 2014-05-28
NZ595863A (en) 2013-03-28
IL193514A0 (en) 2011-08-01
JP2009529892A (ja) 2009-08-27
WO2007106915A8 (fr) 2007-11-22
MX2008011663A (es) 2008-09-22
TW201446798A (zh) 2014-12-16
IL223416A0 (en) 2013-02-03
CA2646513A1 (fr) 2007-09-20
AU2007226522B2 (en) 2012-02-16
WO2007106915A3 (fr) 2008-06-05
EP1994056A2 (fr) 2008-11-26
BRPI0707047A2 (pt) 2011-04-12
KR20080099328A (ko) 2008-11-12
EP2468772A3 (fr) 2013-01-23
JP5364137B2 (ja) 2013-12-11
WO2007106915A2 (fr) 2007-09-20
US20110200602A1 (en) 2011-08-18
AU2007226522A8 (en) 2008-10-02
US20100203041A1 (en) 2010-08-12
US20130129735A1 (en) 2013-05-23
JP5363972B2 (ja) 2013-12-11
EP2468772A2 (fr) 2012-06-27
AR059851A1 (es) 2008-04-30
NO20084320L (no) 2008-12-16
RU2008140947A (ru) 2010-04-27
JP2012036205A (ja) 2012-02-23
EP1994056B1 (fr) 2014-05-07

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