MA29932B1 - Inhibiteurs de la proteine d'activation de la 5-lipoxygenase (flap) - Google Patents
Inhibiteurs de la proteine d'activation de la 5-lipoxygenase (flap)Info
- Publication number
- MA29932B1 MA29932B1 MA30901A MA30901A MA29932B1 MA 29932 B1 MA29932 B1 MA 29932B1 MA 30901 A MA30901 A MA 30901A MA 30901 A MA30901 A MA 30901A MA 29932 B1 MA29932 B1 MA 29932B1
- Authority
- MA
- Morocco
- Prior art keywords
- flap
- activation protein
- inhibitors
- lipoxygenase
- compounds
- Prior art date
Links
- 102000001381 Arachidonate 5-Lipoxygenase Human genes 0.000 title abstract 3
- 108010093579 Arachidonate 5-lipoxygenase Proteins 0.000 title abstract 3
- 230000004913 activation Effects 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000002617 leukotrienes Chemical class 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000002526 effect on cardiovascular system Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 208000023504 respiratory system disease Diseases 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
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- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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Abstract
L'INVENTION CONCERNE DES COMPOSÉS ET DES COMPOSITIONS PHARMACEUTIQUES CONTENANT DE TELS COMPOSÉS QUI MODULENT L'ACTIVITÉ DE LA PROTÉINE D'ACTIVATION DE LA 5-LIPOXYGÉNASE (FLAP). CETTE INVENTION A AUSSI POUR OBJET DES MÉTHODES D'UTILISATION DE TELS MODULATEURS DE LA PROTÉINE D'ACTIVATION DE LA 5-LIPOXYGÉNASE (FLAP), SEULS OU COMBINÉS AVEC D'AUTRES COMPOSÉS, DANS LE TRAITEMENT DE TROUBLES OU DE MALADIES RESPIRATOIRES, CARDIO-VASCULAIRES ET AUTRES DÉPENDANTS DU LEUKOTRIÈNE OU MÉDIÉS PAR LE LEUKOTRIÈNE.
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US73403005P | 2005-11-04 | 2005-11-04 | |
US74717406P | 2006-05-12 | 2006-05-12 | |
US82334406P | 2006-08-23 | 2006-08-23 |
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MA29932B1 true MA29932B1 (fr) | 2008-11-03 |
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MA30901A MA29932B1 (fr) | 2005-11-04 | 2008-05-05 | Inhibiteurs de la proteine d'activation de la 5-lipoxygenase (flap) |
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US (3) | US8841295B2 (fr) |
EP (2) | EP1942896A4 (fr) |
JP (2) | JP2009514959A (fr) |
KR (1) | KR20080066989A (fr) |
AR (3) | AR057872A1 (fr) |
AU (2) | AU2006311804A1 (fr) |
BR (1) | BRPI0618047A2 (fr) |
CA (2) | CA2628233A1 (fr) |
CR (1) | CR9949A (fr) |
EA (1) | EA200801164A3 (fr) |
GB (1) | GB2431927B (fr) |
IL (1) | IL190872A0 (fr) |
MA (1) | MA29932B1 (fr) |
NO (1) | NO20081839L (fr) |
SG (1) | SG165387A1 (fr) |
TW (4) | TW200804276A (fr) |
WO (2) | WO2007056228A2 (fr) |
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2006
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- 2006-11-03 EP EP06827508A patent/EP1942896A4/fr not_active Withdrawn
- 2006-11-03 SG SG201006712-2A patent/SG165387A1/en unknown
- 2006-11-03 TW TW095140880A patent/TW200804276A/zh unknown
- 2006-11-03 US US12/089,706 patent/US8841295B2/en not_active Expired - Fee Related
- 2006-11-03 WO PCT/US2006/043108 patent/WO2007056228A2/fr active Application Filing
- 2006-11-03 EP EP06836946A patent/EP1943266A4/fr not_active Withdrawn
- 2006-11-03 WO PCT/US2006/043095 patent/WO2007056220A2/fr active Application Filing
- 2006-11-03 EA EA200801164A patent/EA200801164A3/ru unknown
- 2006-11-03 TW TW102131359A patent/TW201402562A/zh unknown
- 2006-11-03 TW TW095140834A patent/TW200804334A/zh unknown
- 2006-11-03 KR KR1020087013546A patent/KR20080066989A/ko not_active Application Discontinuation
- 2006-11-03 AU AU2006311804A patent/AU2006311804A1/en not_active Abandoned
- 2006-11-03 JP JP2008540097A patent/JP2009514959A/ja active Pending
- 2006-11-03 AR ARP060104837A patent/AR057872A1/es not_active Application Discontinuation
- 2006-11-03 BR BRPI0618047-7A patent/BRPI0618047A2/pt not_active IP Right Cessation
- 2006-11-03 CA CA002628233A patent/CA2628233A1/fr not_active Abandoned
- 2006-11-03 AU AU2006311796A patent/AU2006311796A1/en not_active Abandoned
- 2006-11-03 JP JP2008539090A patent/JP5320590B2/ja not_active Expired - Fee Related
- 2006-11-03 AR ARP060104838A patent/AR056214A1/es not_active Application Discontinuation
- 2006-11-03 CA CA002628467A patent/CA2628467A1/fr not_active Abandoned
- 2006-11-06 AR ARP060104861A patent/AR056215A1/es not_active Application Discontinuation
- 2006-11-06 TW TW095141065A patent/TW200804277A/zh unknown
-
2007
- 2007-10-27 US US11/925,841 patent/US7834037B2/en not_active Expired - Fee Related
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2008
- 2008-04-15 IL IL190872A patent/IL190872A0/en unknown
- 2008-04-16 NO NO20081839A patent/NO20081839L/no not_active Application Discontinuation
- 2008-04-30 CR CR9949A patent/CR9949A/es not_active Application Discontinuation
- 2008-05-05 MA MA30901A patent/MA29932B1/fr unknown
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2010
- 2010-10-18 US US12/906,325 patent/US20110034514A1/en not_active Abandoned
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