GB2431927A9 - 1,2-Disubstituted indoles & derivatives thereof astherapeutic 5-iipoxygenase-activating protein (fl ap) inhibitors - Google Patents

1,2-Disubstituted indoles & derivatives thereof astherapeutic 5-iipoxygenase-activating protein (fl ap) inhibitors Download PDF

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Publication number
GB2431927A9
GB2431927A9 GB0621651A GB0621651A GB2431927A9 GB 2431927 A9 GB2431927 A9 GB 2431927A9 GB 0621651 A GB0621651 A GB 0621651A GB 0621651 A GB0621651 A GB 0621651A GB 2431927 A9 GB2431927 A9 GB 2431927A9
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United Kingdom
Prior art keywords
astherapeutic
iipoxygenase
inhibitors
derivatives
activating protein
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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GB0621651A
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GB2431927A (en
GB2431927B (en
GB0621651D0 (en
Inventor
John H Hutchinson
Petpiboon Peppi Prasit
Mark Moran
Killian F Evans
Brian Andrew Stearns
Jeffrey Roger Roppe
Yiwei Li
Jasmine Eleanor Zunic
Jeannie M Arrunda
Nicholas Simon Stock
Mustapha Haddach
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Amira Pharmaceuticals Inc
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Amira Pharmaceuticals Inc
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Application filed by Amira Pharmaceuticals Inc filed Critical Amira Pharmaceuticals Inc
Publication of GB0621651D0 publication Critical patent/GB0621651D0/en
Publication of GB2431927A publication Critical patent/GB2431927A/en
Publication of GB2431927A9 publication Critical patent/GB2431927A9/en
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Publication of GB2431927B publication Critical patent/GB2431927B/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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