MA22970A1 - Procede de praparation de nouveaux composes. - Google Patents
Procede de praparation de nouveaux composes.Info
- Publication number
- MA22970A1 MA22970A1 MA23279A MA23279A MA22970A1 MA 22970 A1 MA22970 A1 MA 22970A1 MA 23279 A MA23279 A MA 23279A MA 23279 A MA23279 A MA 23279A MA 22970 A1 MA22970 A1 MA 22970A1
- Authority
- MA
- Morocco
- Prior art keywords
- preparation
- new compounds
- compounds
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Nutrition Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929218830A GB9218830D0 (en) | 1992-09-05 | 1992-09-05 | Novel compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
MA22970A1 true MA22970A1 (fr) | 1994-04-01 |
Family
ID=10721461
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA23279A MA22970A1 (fr) | 1992-09-05 | 1993-09-03 | Procede de praparation de nouveaux composes. |
Country Status (38)
Country | Link |
---|---|
US (1) | US5910592A (fr) |
EP (2) | EP0658161B1 (fr) |
JP (5) | JP2828777B2 (fr) |
KR (3) | KR100371297B1 (fr) |
CN (4) | CN1040323C (fr) |
AP (1) | AP513A (fr) |
AT (1) | ATE182147T1 (fr) |
AU (1) | AU674880B2 (fr) |
BR (1) | BR1100916A (fr) |
CA (2) | CA2273147A1 (fr) |
CY (1) | CY2138B1 (fr) |
CZ (2) | CZ287473B6 (fr) |
DE (2) | DE69325658T2 (fr) |
DK (1) | DK0658161T3 (fr) |
ES (1) | ES2133410T3 (fr) |
FI (2) | FI106263B (fr) |
GB (1) | GB9218830D0 (fr) |
GR (1) | GR3030794T3 (fr) |
HK (1) | HK1012363A1 (fr) |
HU (2) | HU0500355D0 (fr) |
IL (1) | IL106904A (fr) |
LU (1) | LU90712I2 (fr) |
MA (1) | MA22970A1 (fr) |
MX (1) | MX9305397A (fr) |
MY (1) | MY111190A (fr) |
NL (1) | NL300035I2 (fr) |
NO (4) | NO303016B1 (fr) |
NZ (1) | NZ255505A (fr) |
PL (1) | PL173725B1 (fr) |
RU (3) | RU2128179C1 (fr) |
SA (1) | SA93140245B1 (fr) |
SG (2) | SG83747A1 (fr) |
SI (1) | SI9300452B (fr) |
SK (1) | SK280777B6 (fr) |
TW (1) | TW385309B (fr) |
UA (1) | UA41901C2 (fr) |
WO (1) | WO1994005659A1 (fr) |
ZA (1) | ZA936509B (fr) |
Families Citing this family (108)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9308487D0 (en) * | 1993-04-23 | 1993-06-09 | Smithkline Beecham Plc | Novel compounds |
ZA973850B (en) * | 1996-05-06 | 1997-12-02 | Reddy Research Foundation | Novel antidiabetic compounds having hypolipidaemic, anti-hypertensive properties, process for their preparation and pharmaceutical compositions containing them. |
US5801173A (en) * | 1996-05-06 | 1998-09-01 | Dr. Reddy's Research Foundation | Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them |
ZA973848B (en) * | 1996-05-06 | 1997-12-02 | Reddy Research Foundation | Novel heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them. |
US5919782A (en) * | 1996-05-06 | 1999-07-06 | Dr. Reddy's Research Foundation | Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them |
US5885997A (en) * | 1996-07-01 | 1999-03-23 | Dr. Reddy's Research Foundation | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases |
USRE39266E1 (en) * | 1996-07-01 | 2006-09-05 | Dr. Reddy's Laboratories, Limited | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases |
US6114526A (en) * | 1996-07-01 | 2000-09-05 | Dr. Reddy's Research Foundation | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases |
US6372750B2 (en) | 1996-07-01 | 2002-04-16 | Dr. Reddy's Research Foundation | Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases |
US5985884A (en) * | 1996-07-01 | 1999-11-16 | Dr. Reddy's Research Foundation | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases |
TR199900056T2 (xx) * | 1996-07-12 | 1999-04-21 | Smithkline Beecham P.L.C. | Leptin direncinin yeni tedavisi. |
GB9711683D0 (en) * | 1997-06-05 | 1997-08-06 | Smithkline Beecham Plc | Composition |
AU8539298A (en) * | 1997-06-18 | 1999-01-04 | Smithkline Beecham Plc | Treatment of diabetes with thiazolidinedione and sulphonylurea |
AU8539398A (en) * | 1997-06-18 | 1999-01-04 | Smithkline Beecham Plc | Treatment of diabetes with thiazolidinedione and metformin |
GB9715306D0 (en) * | 1997-07-18 | 1997-09-24 | Smithkline Beecham Plc | Novel method of treatment |
GB9721693D0 (en) * | 1997-10-13 | 1997-12-10 | Smithkline Beecham Plc | Novel treatment |
GB9721692D0 (en) * | 1997-10-13 | 1997-12-10 | Smithkline Beecham Plc | Novel treatment |
US20020006939A1 (en) * | 1997-10-13 | 2002-01-17 | Smithkline Beecham P.L.C. | Use of thiazolidinediones for the treatment of hyperglycaemia |
US20010031776A1 (en) * | 1997-10-13 | 2001-10-18 | Smithkline Beecham P.L.C. | Use of thiazolidinediones for the treatment of hyperglycaemia |
US7091359B2 (en) | 1997-11-04 | 2006-08-15 | Smithkline Beecham Plc | Process for the preparation of thiazolidinedione derivatives |
GB9723295D0 (en) | 1997-11-04 | 1998-01-07 | Smithkline Beecham Plc | Novel process |
AU774613B2 (en) * | 1997-12-16 | 2004-07-01 | Smithkline Beecham Plc | Hydrate of 5-(4-(2- (N-methyl-N- (2-pyridil)amino) ethoxy)benzyl) thiazolidine-2,4-dione maleic acid salt |
US20020137940A1 (en) * | 1997-12-16 | 2002-09-26 | Smithkline Beecham P.L.C. | 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical |
GB9726568D0 (en) * | 1997-12-16 | 1998-02-11 | Smithkline Beecham Plc | Novel pharmaceutical |
AU770817B2 (en) * | 1997-12-16 | 2004-03-04 | Smithkline Beecham Plc | 5-(4-(2-(N-methyl-N-(2-pyridyl)amino)ethoxy)benzyl) thiazolidine-2,dione,maleic acid salt, hydrate as pharmaceutical |
GB9726563D0 (en) * | 1997-12-16 | 1998-02-11 | Smithkline Beecham Plc | Novel pharmaceutical |
US6664278B2 (en) | 1997-12-16 | 2003-12-16 | Smithkline Beecham P.L.C. | Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt |
GB9726566D0 (en) * | 1997-12-16 | 1998-02-11 | Smithkline Beecham Plc | Novel pharmaceutical |
DK1098639T3 (da) * | 1998-07-21 | 2005-06-13 | Smithkline Beecham Plc | Anvendelse af glucoseoptagelsesforstærkeren rosiglitazon til reduktion af iskæmiinduceret apoptose af pankreatiske beta-celler, endotelceller og neuronale celler |
MA26662A1 (fr) * | 1998-07-21 | 2004-12-20 | Smithkline Beecham Plc | Derives de thiazolidinedione, compositions pharmaceutiques les contenant et leur utilisation |
US6613785B2 (en) | 1998-07-21 | 2003-09-02 | Smithkline Beecham Plc | Use of glucose uptake enhancer for reducing post-ischemic injury of the heart |
US20030153607A1 (en) * | 1998-11-12 | 2003-08-14 | Smithkline Beecham P.L.C. | Novel composition and use |
US20040102486A1 (en) * | 1998-11-12 | 2004-05-27 | Smithkline Beecham Corporation | Novel method of treatment |
KR100643833B1 (ko) | 1998-11-12 | 2006-11-10 | 스미스클라인비이참피이엘시이 | 인슐린 감작제 및 다른 항당뇨병 약제의 개선된 방출을위한 제약 조성물 |
GB9824893D0 (en) * | 1998-11-12 | 1999-01-06 | Smithkline Beckman Corp | Novel method of treatment |
AR023700A1 (es) | 1998-11-12 | 2002-09-04 | Smithkline Beecham Plc | Un procedimiento para preparar una composicion farmaceutica que comprende un sensibilizador de insulina |
GB9909041D0 (en) * | 1999-04-20 | 1999-06-16 | Smithkline Beecham Plc | Novel pharmaceutical |
GB9909075D0 (en) * | 1999-04-20 | 1999-06-16 | Smithkline Beecham Plc | Novel pharmaceutical |
PE20010045A1 (es) * | 1999-04-23 | 2001-03-10 | Smithkline Beecham Plc | Polimorfo de sal del acido maleico de 5-[4-[2-(n-metil-n-(2-piridil)amino)etoxi]bencil]-tiazolidin-2,4-diona |
ES2203453T3 (es) * | 1999-04-23 | 2004-04-16 | Smithkline Beecham Plc | Polimorfo de sal del acido maleico de 5-(4-(2-(n-metil-n-(2-piridil)amino)etoxi)bentil)tiazolidina-2,4-diona. |
US20040248945A1 (en) | 1999-04-23 | 2004-12-09 | Smithkline Beecham P.L.C. | Thiazolidinedione derivative and its use as antidiabetic |
OA11871A (en) * | 1999-04-23 | 2006-03-27 | Smithkline Beecham Plc | Novel pharmaceutical. |
BR0013375A (pt) * | 1999-08-17 | 2002-07-23 | Smithkline Beecham Plc | Composições farmacêuticas contendo derivados tiazolidinodiona e processo para sua preparação |
MY125516A (en) * | 1999-11-16 | 2006-08-30 | Smithkline Beecham Plc | Novel composition based on thiazolidinedione and metformin and use |
GB0006133D0 (en) * | 2000-03-14 | 2000-05-03 | Smithkline Beecham Plc | Novel pharmaceutical |
GB0014006D0 (en) * | 2000-06-08 | 2000-08-02 | Smithkline Beecham Plc | Novel pharmaceutical |
GB0014005D0 (en) * | 2000-06-08 | 2000-08-02 | Smithkline Beecham Plc | Novel pharmaceutical |
WO2001095906A1 (fr) * | 2000-06-16 | 2001-12-20 | Smithkline Beecham P.L.C. | Traitement et prevention des etats associes a l'insulino-resistance cardiaque |
GB0014969D0 (en) | 2000-06-19 | 2000-08-09 | Smithkline Beecham Plc | Novel method of treatment |
AU2005229687B2 (en) * | 2000-08-04 | 2008-03-13 | Smithkline Beecham P.L.C. | Tartrate salts of thiazolidinedione derivative |
GB0019224D0 (en) * | 2000-08-04 | 2000-09-27 | Smithkline Beecham Plc | Novel pharmaceutical |
GB0019228D0 (en) * | 2000-08-04 | 2000-09-27 | Smithkline Beecham Plc | Novel pharmaceutical |
GB0019223D0 (en) * | 2000-08-04 | 2000-09-27 | Smithkline Beecham Plc | Novel pharmaceutical |
GB0019226D0 (en) * | 2000-08-04 | 2000-09-27 | Smithkline Beecham Plc | Novel pharmaceutical |
AU2005229688B2 (en) * | 2000-08-04 | 2008-04-03 | Smithkline Beecham P.L.C. | Tartrate salts of thiazolidinedione derivative |
GB0021784D0 (en) * | 2000-09-05 | 2000-10-18 | Smithkline Beecham Plc | Novel pharmaceutical |
GB0021785D0 (en) * | 2000-09-05 | 2000-10-18 | Smithkline Beecham Plc | Novel Pharmaceutical |
GB0021865D0 (en) * | 2000-09-06 | 2000-10-18 | Smithkline Beecham Plc | Novel pharmaceutical |
GB0021978D0 (en) * | 2000-09-07 | 2000-10-25 | Smithkline Beecham Plc | Novel pharmaceutical |
US7241895B2 (en) | 2000-09-26 | 2007-07-10 | Dr. Reddy's Laboratories Limited | Polymorphic forms of 5-[4-[2-[n-methyl-n-(2-pyridyl)amino[ethoxy]benzyl] thiazolidine-2,4-dione maleate and process for their preparation |
EP1322647A1 (fr) * | 2000-09-26 | 2003-07-02 | Dr. Reddy's Research Foundation | Nouvelles formes polymorphes de 5- 4- 2- n-methyl-n-(2-pyridyl)amino]ethoxy]benzyl] thiazolidine-2,4-dione maleate et procede de preparation associe |
GB0023971D0 (en) * | 2000-09-29 | 2000-11-15 | Smithkline Beecham Plc | Novel pharmaceutical |
ATE337313T1 (de) * | 2000-12-22 | 2006-09-15 | Smithkline Beecham Plc | 5-4'-2'-(n-methyl-n-(2-pyridyl)amino) ethoxy)benzyl)thiazolidin-2,4-dion mesylatsalz |
WO2002051823A1 (fr) | 2000-12-26 | 2002-07-04 | Torrent Pharmaceuticals Ltd | Procede de preparation de maleate de rosiglitazone |
GB0127805D0 (en) | 2001-11-20 | 2002-01-09 | Smithkline Beecham Plc | Pharmaceutical composition |
DE60217168T2 (de) * | 2001-11-21 | 2007-10-04 | Smithkline Beecham Plc, Brentford | 5-(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4-dion-benzolsulfonat; prozess zu seiner herstellung; polymorphe i, ii und iii davon; und seine verwendung als pharmazeutischer wirkstoff |
ES2266593T3 (es) * | 2001-11-21 | 2007-03-01 | Smithkline Beecham Plc | Edisilatos de rosiglitazona y su uso como antidiabeticos. |
WO2003050112A1 (fr) * | 2001-12-13 | 2003-06-19 | Smithkline Beecham Plc | Hydrates de toluenesulfonate d'un derive de thiazolidinedione |
AU2002352391A1 (en) * | 2001-12-13 | 2003-06-23 | Smithkline Beecham Plc | A 5(-4-(2-(n-methyl-n-(2-pyridil)amino)ethoxy)benzyl)thiazolidine-2,4-dione (i) 10-camphorsulphonic acid salt and use against diabetes mellitus |
GB0129876D0 (en) * | 2001-12-13 | 2002-02-06 | Smithkline Beecham Plc | Novel pharmaceutical |
GB0129872D0 (en) * | 2001-12-13 | 2002-02-06 | Smithkline Beecham Plc | Novel pharmaceutical |
GB0129871D0 (en) * | 2001-12-13 | 2002-02-06 | Smithkline Beecham Plc | Novel pharmaceutical |
GB0129851D0 (en) * | 2001-12-13 | 2002-01-30 | Smithkline Beecham Plc | Novel compounds |
GB0130510D0 (en) * | 2001-12-20 | 2002-02-06 | Smithkline Beecham Plc | Novel pharmaceutical |
GB0130511D0 (en) * | 2001-12-20 | 2002-02-06 | Smithkline Beecham Plc | Novel pharmaceutical |
AU2002352479A1 (en) * | 2001-12-20 | 2003-07-09 | Smithkline Beecham Plc | 5- (4- (2- (n-methyl-n- (2-pyridyl) amino) ethoxy) benzyl) thiazolidine-2, 4-dione malic acid salt and use against diabetes mellitus |
GB0130509D0 (en) * | 2001-12-20 | 2002-02-06 | Smithkline Beecham Plc | Novel pharmaceutical |
US8216609B2 (en) | 2002-08-05 | 2012-07-10 | Torrent Pharmaceuticals Limited | Modified release composition of highly soluble drugs |
US8268352B2 (en) | 2002-08-05 | 2012-09-18 | Torrent Pharmaceuticals Limited | Modified release composition for highly soluble drugs |
US7232828B2 (en) | 2002-08-10 | 2007-06-19 | Bethesda Pharmaceuticals, Inc. | PPAR Ligands that do not cause fluid retention, edema or congestive heart failure |
WO2004062667A1 (fr) * | 2003-01-08 | 2004-07-29 | Dr. Reddy's Laboratories Limited | Forme amorphe du maleate de rosiglitazone et procede de preparation |
GB0307259D0 (en) * | 2003-03-28 | 2003-05-07 | Glaxo Group Ltd | Process |
GB2405403A (en) * | 2003-08-29 | 2005-03-02 | Cipla Ltd | Rosiglitazone maleate of particular polymorphic forms and methods of preparing rosiglitazone free base |
WO2005058813A2 (fr) * | 2003-12-17 | 2005-06-30 | Ranbaxy Laboratories Limited | Agents antidiabetiques |
WO2005065654A2 (fr) * | 2003-12-31 | 2005-07-21 | Alpharma, Inc. | Preparations de rosiglitazone |
EP1709038A2 (fr) * | 2004-01-28 | 2006-10-11 | Usv Limited | Procede de preparation de maleate de 5- 4- 2- n-methyl-n-(2-pyridyl) amino¨ ethoxy¨ phenyl methyl¨ thiazolidine-2, 4-dione |
GB2421240A (en) * | 2004-12-14 | 2006-06-21 | Sandoz Ag | Phosphoric acid salt of rosiglitazone |
GB2410948A (en) * | 2004-02-13 | 2005-08-17 | Sandoz Ag | Novel phosphoric acid salt of rosiglitazone |
AR047541A1 (es) * | 2004-02-13 | 2006-01-25 | Sandoz Ag | Fosfato de 5-[[4-[2-metil-2-piridinil-amino-etoxi]fenil]metil]-2,4 tiazolidinadiona (rosiglitazona) y sus formas polimorficas |
CZ296468B6 (cs) * | 2004-06-10 | 2006-03-15 | Zentiva, A. S. | Sul kyseliny fosforecné s 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidin-2,4-dionema zpusob její prípravy |
CZ2004844A3 (cs) * | 2004-07-27 | 2006-03-15 | Zentiva, A. S | Sul kyseliny stavelové s 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidin-2,4-dionu azpusob její prípravy a její pouzití |
CZ298424B6 (cs) * | 2005-05-24 | 2007-09-26 | Zentiva, A. S. | Zpusob krystalizace rosiglitazonu a jeho derivátuze smesných rozpouštedel |
DE102005034406A1 (de) * | 2005-07-22 | 2007-02-01 | Ratiopharm Gmbh | Neue Salze von Rosiglitazon |
KR100749219B1 (ko) * | 2006-03-15 | 2007-08-13 | 건일제약 주식회사 | 신규한 로지글리타존 옥살산염, 이의 제조방법, 및 이를포함하는 약제학적 조성물 |
US7435741B2 (en) | 2006-05-09 | 2008-10-14 | Teva Pharmaceutical Industries, Ltd. | 2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate |
NZ574710A (en) | 2006-09-07 | 2012-02-24 | Nycomed Gmbh | Combination treatment comprising the PDE4 inhibitor Compound A ((2R,4aR, 10bR)6-(2,6-Dimethoxy-pyridin-3-yl)-9-ethoxy-8-methoxy-1 ,2,3,4,4a,10b-hexahydrophenanthridin-2-ol) for diabetes mellitus |
US7645616B2 (en) * | 2006-10-20 | 2010-01-12 | The University Of Hong Kong | Use of lipocalin-2 as a diagnostic marker and therapeutic target |
EP1967182A1 (fr) * | 2007-03-07 | 2008-09-10 | KRKA, tovarna zdravil, d.d., Novo mesto | Composition pharmaceutique comprenant un sel de rosiglitazone |
CA2690004C (fr) | 2007-06-04 | 2018-01-23 | Ben-Gurion University Of The Negev Research And Development Authority | Composes triaryles et compositions les comprenant |
CN101167726B (zh) * | 2007-10-16 | 2011-05-18 | 宁夏康亚药业有限公司 | 马来酸罗格列酮分散片及其制备方法 |
PL384446A1 (pl) * | 2008-02-12 | 2009-08-17 | Adamed Spółka Z Ograniczoną Odpowiedzialnością | Sól 5-[[4-[2-(metylo-2-pirydynyloamino)etoksy]fenylo]metylo]-2,4-tiazolidynodionu z kwasem malonowym i sposób jej wytwarzania |
EP2184055A1 (fr) | 2008-11-07 | 2010-05-12 | LEK Pharmaceuticals d.d. | Procédé de préparation de formes galéniques solides de maléate de rosiglitazone |
DE102009053562A1 (de) | 2009-11-18 | 2011-05-19 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Rosiglitazonsuccinat enthaltende pharmazeutische Zusammensetzung |
US20120094959A1 (en) | 2010-10-19 | 2012-04-19 | Bonnie Blazer-Yost | Treatment of cystic diseases |
CN102532122B (zh) * | 2010-12-29 | 2015-12-02 | 开封制药(集团)有限公司 | 酒石酸罗格列酮的制备方法 |
KR20160094956A (ko) | 2013-11-05 | 2016-08-10 | 벤-구리온 유니버시티 오브 더 네게브 리서치 앤드 디벨럽먼트 어쏘러티 | 당뇨병 및 당뇨병으로부터 발생하는 합병증 질환의 치료를 위한 화합물 |
WO2016071727A1 (fr) | 2014-11-04 | 2016-05-12 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Méthodes pour la prévention et le traitement de la glomérulonéphrite rapidement progressive |
IT201800002630A1 (it) * | 2018-02-13 | 2019-08-13 | Giuliani Spa | Composizione per la prevenzione e il trattamento dei disturbi della crescita dei capelli |
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US4197297A (en) * | 1976-11-17 | 1980-04-08 | Smithkline Corporation | 6-Halo-7,8-dihydroxy-1-(hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepines |
US4405211A (en) * | 1980-07-29 | 1983-09-20 | The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland | Liquid crystal compositions with pleochroic anthraquinone dyes |
AR240698A1 (es) * | 1985-01-19 | 1990-09-28 | Takeda Chemical Industries Ltd | Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales |
US5039687A (en) * | 1985-12-04 | 1991-08-13 | Hoechst-Roussel Pharmaceuticals Inc. | N-(pyrrol-1-yl)pyridinamine compounds having enhancing activity |
EP0842925A1 (fr) * | 1987-09-04 | 1998-05-20 | Beecham Group Plc | Thiazolidinédiones substituées |
US5232925A (en) * | 1987-09-04 | 1993-08-03 | Beecham Group P.L.C. | Compounds |
GB8919434D0 (en) * | 1989-08-25 | 1989-10-11 | Beecham Group Plc | Novel compounds |
GB8919417D0 (en) * | 1989-08-25 | 1989-10-11 | Beecham Group Plc | Novel compounds |
GB9023583D0 (en) * | 1990-10-30 | 1990-12-12 | Beecham Group Plc | Novel compounds |
-
1992
- 1992-09-05 GB GB929218830A patent/GB9218830D0/en active Pending
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1993
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- 1993-09-01 JP JP6506983A patent/JP2828777B2/ja not_active Expired - Lifetime
- 1993-09-01 CA CA002273147A patent/CA2273147A1/fr not_active Abandoned
- 1993-09-01 WO PCT/GB1993/001853 patent/WO1994005659A1/fr active Application Filing
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