LV12888B - 3- (COMPLETED BY NUCLEAR ATOMIC) FENIL-5-BETA-AMIDOMETHYL-OZZOLIDIN-2-ONI - Google Patents

3- (COMPLETED BY NUCLEAR ATOMIC) FENIL-5-BETA-AMIDOMETHYL-OZZOLIDIN-2-ONI Download PDF

Info

Publication number
LV12888B
LV12888B LVP-02-104A LV020104A LV12888B LV 12888 B LV12888 B LV 12888B LV 020104 A LV020104 A LV 020104A LV 12888 B LV12888 B LV 12888B
Authority
LV
Latvia
Prior art keywords
alkyl
defined above
optionally substituted
oxazolidin
taken together
Prior art date
Application number
LVP-02-104A
Other languages
English (en)
Latvian (lv)
Inventor
Steven L. Brickner
Original Assignee
Pharmacia & Upjohn Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Company filed Critical Pharmacia & Upjohn Company
Publication of LV12888B publication Critical patent/LV12888B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
LVP-02-104A 1988-09-15 2002-06-06 3- (COMPLETED BY NUCLEAR ATOMIC) FENIL-5-BETA-AMIDOMETHYL-OZZOLIDIN-2-ONI LV12888B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24498888A 1988-09-15 1988-09-15
US25385088A 1988-10-05 1988-10-05
US32494289A 1989-03-17 1989-03-17

Publications (1)

Publication Number Publication Date
LV12888B true LV12888B (en) 2002-12-20

Family

ID=27399816

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-02-104A LV12888B (en) 1988-09-15 2002-06-06 3- (COMPLETED BY NUCLEAR ATOMIC) FENIL-5-BETA-AMIDOMETHYL-OZZOLIDIN-2-ONI

Country Status (14)

Country Link
EP (3) EP0609905B1 (fr)
JP (2) JP2865211B2 (fr)
KR (1) KR0138262B1 (fr)
AT (2) ATE112773T1 (fr)
AU (1) AU617871B2 (fr)
CA (1) CA1335103C (fr)
DE (2) DE68918792T2 (fr)
DK (2) DK175696B1 (fr)
ES (1) ES2157934T3 (fr)
GR (1) GR3036491T3 (fr)
HK (1) HK1002234A1 (fr)
LV (1) LV12888B (fr)
TW (1) TW219936B (fr)
WO (1) WO1990002744A1 (fr)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231188A (en) * 1989-11-17 1993-07-27 The Upjohn Company Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents
CA2064815C (fr) * 1990-06-07 1999-11-16 Alan Duncan Robertson Composes heterocycliques therapeutiques
CA2115029C (fr) * 1991-08-14 2002-03-26 Stanford Salvatore Pelosi, Jr. Urethanes cycliques utilises comme agents antiarythmiques et antifibrillants
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
EP0648119A1 (fr) * 1992-07-08 1995-04-19 The Upjohn Company UTILISATION DE 5'-INDOLINYLOXAZOLIDINONES CONTRE LE $i(MYCOBACTERIUM TUBERCULOSIS)
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
DE4425612A1 (de) * 1994-07-20 1996-04-04 Bayer Ag 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
DE4425609A1 (de) * 1994-07-20 1996-01-25 Bayer Ag Benzofuranyl- und Benzothienyloxazolidinone
DE4425613A1 (de) * 1994-07-20 1996-01-25 Bayer Ag 5-gliedrige Heteroaryl-oxazolidinone
DE19514313A1 (de) * 1994-08-03 1996-02-08 Bayer Ag Benzoxazolyl- und Benzothiazolyloxazolidinone
ATE204277T1 (de) * 1994-10-26 2001-09-15 Upjohn Co Phenyloxazolidinone mit antimikrobieller wirkung
DE69529838T2 (de) * 1994-11-15 2003-11-13 Upjohn Co Antibakterielle bizyklische oxazin und thiazin-oxazolidinone
WO1996023788A1 (fr) * 1995-02-03 1996-08-08 Pharmacia + Upjohn Company Phenyloxazolidinone substituee par un noyau heteroaromatique comme agent antimicrobien
HRP960159A2 (en) * 1995-04-21 1997-08-31 Bayer Ag Benzocyclopentane oxazolidinones containing heteroatoms
NZ306310A (en) * 1995-05-11 2001-05-25 Upjohn Co Spirocyclic and bicyclic diazinyl and carbazinyl oxazolidinones
MX9703040A (es) * 1995-09-12 1997-07-31 Upjohn Co Antimicrobianos de feniloxazolidinona.
ZA968661B (en) * 1995-11-17 1998-04-14 Upjohn Co Oxazolidinone antibacterial agent with tricyclic substituents.
DE19601264A1 (de) * 1996-01-16 1997-07-17 Bayer Ag Pyrido-annellierte Thienyl- und Furanyl-Oxazolidinone
DE19601265A1 (de) 1996-01-16 1997-07-17 Bayer Ag 2-Oxo- und 2-Thio-1,2-dihydrochinolinyl-oxazolidinone
DE19601627A1 (de) * 1996-01-18 1997-07-24 Bayer Ag Heteroatomhaltige Cyclopentanopyridyl-Oxazolidinone
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
HRP970049A2 (en) 1996-02-06 1998-04-30 Bayer Ag New heteroaryl oxazolidinones
DE19604223A1 (de) 1996-02-06 1997-08-07 Bayer Ag Neue substituierte Oxazolidinone
GB9702213D0 (en) * 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
US6255304B1 (en) 1997-05-30 2001-07-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
JP2002501530A (ja) 1997-05-30 2002-01-15 ファルマシア・アンド・アップジョン・カンパニー チオカルボニル官能基を有するオキサゾリジノン抗菌剤
DE19730847A1 (de) * 1997-07-18 1999-01-28 Bayer Ag Tricyclisch substituierte Oxazolidinone
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
US5998406A (en) * 1997-11-12 1999-12-07 Pharmacia & Upjohn Company Oxazolidinone derivatives and pharmaceutical compositions
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
DE19802239A1 (de) * 1998-01-22 1999-07-29 Bayer Ag Neue mit Bicyclen substituierte Oxazolidinone
US6562844B2 (en) 1998-01-23 2003-05-13 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
AU764184B2 (en) * 1998-01-23 2003-08-14 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US7002020B1 (en) 1998-01-23 2006-02-21 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
CA2372233A1 (fr) 1999-05-27 2000-12-07 Pharmacia & Upjohn Company Oxazolidinones bicycliques en tant qu'agents antibacteriens
CN1367780A (zh) * 1999-07-28 2002-09-04 法玛西雅厄普约翰美国公司 噁唑烷酮类化合物、其制备方法及其应用
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
SK1402003A3 (en) 2000-07-17 2003-08-05 Ranbaxy Lab Ltd Oxazolidinone derivatives as antimicrobials
DE60121986T2 (de) 2000-10-02 2007-07-26 Emory University Triptpolidanaloge zur verendung in der behandlung von autoimmunbedingten und entzündlichen erkrankungen
PE20020689A1 (es) 2000-11-17 2002-08-03 Upjohn Co Oxazolidinonas con un heterociclo de 6 o 7 miembros unidos con enlace anular al benceno
US6956040B2 (en) 2001-07-16 2005-10-18 Ranbaxy Laboratories Limited Oxazolidinone piperazinyl derivatives as potential antimicrobials
GB0118407D0 (en) * 2001-07-27 2001-09-19 Cipla Ltd Oxazolidinone derivatives as antibacterial agents
TW200306819A (en) 2002-01-25 2003-12-01 Vertex Pharma Indazole compounds useful as protein kinase inhibitors
US7012088B2 (en) * 2003-02-24 2006-03-14 Pharmacia & Upjohn Company Indolone oxazolidinones and derivatives thereof
US20080262056A1 (en) * 2004-08-06 2008-10-23 Pfizer Inc Oxindole Oxazolidinones as Antibacterial Agents
SE0402763D0 (sv) * 2004-11-11 2004-11-11 Astrazeneca Ab Nitro indazole derivatives
KR20070116989A (ko) * 2005-04-06 2007-12-11 파마시아 앤드 업존 캄파니 엘엘씨 항균제로서의 옥신돌 옥사졸리디논
AU2006231919A1 (en) 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents
US8461388B2 (en) * 2007-12-24 2013-06-11 Cipla Limited Process for the synthesis of propargylated aminoindan derivatives
CA2794153C (fr) 2010-03-25 2018-01-02 Glaxosmithkline Llc Derives d'indoline substitue comme inhibiteurs de perk

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8506659A1 (es) * 1983-06-07 1985-08-01 Du Pont Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno.
CA1260948A (fr) * 1984-12-05 1989-09-26 E. I. Du Pont De Nemours And Company Derives d'aminomethyloxo-oxazolidinylbenzene, agents antibacteriens
US4801600A (en) * 1987-10-09 1989-01-31 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents

Also Published As

Publication number Publication date
AU4195789A (en) 1990-04-02
EP0359418A1 (fr) 1990-03-21
DK175696B1 (da) 2005-01-24
DE68929303T2 (de) 2002-05-02
CA1335103C (fr) 1995-04-04
ATE112773T1 (de) 1994-10-15
EP0609905A1 (fr) 1994-08-10
TW219936B (fr) 1994-02-01
JPH04500665A (ja) 1992-02-06
JPH1180139A (ja) 1999-03-26
DE68918792D1 (de) 1994-11-17
JP3188418B2 (ja) 2001-07-16
ATE201870T1 (de) 2001-06-15
DK45591D0 (da) 1991-03-13
EP0359418B1 (fr) 1994-10-12
GR3036491T3 (en) 2001-11-30
JP2865211B2 (ja) 1999-03-08
EP0609905B1 (fr) 2001-06-06
DE68929303D1 (de) 2001-07-12
EP0434714A1 (fr) 1991-07-03
DK175940B1 (da) 2005-08-01
KR900701780A (ko) 1990-12-04
KR0138262B1 (ko) 1998-05-15
DK200401246A (da) 2004-08-18
AU617871B2 (en) 1991-12-05
HK1002234A1 (en) 1998-08-07
WO1990002744A1 (fr) 1990-03-22
DK45591A (da) 1991-03-13
DE68918792T2 (de) 1995-03-30
ES2157934T3 (es) 2001-09-01

Similar Documents

Publication Publication Date Title
LV12888B (en) 3- (COMPLETED BY NUCLEAR ATOMIC) FENIL-5-BETA-AMIDOMETHYL-OZZOLIDIN-2-ONI
US5164510A (en) 5'Indolinyl-5β-amidomethyloxazolidin-2-ones
EP1497279B1 (fr) Indoles substitues et leur utilisation comme inhibiteurs de recapture 5ht et comme ligands 5ht
US5182403A (en) Substituted 3(5'indazolyl) oxazolidin-2-ones
US5225565A (en) Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones
AU2009330686B2 (en) Compounds for the treatment of cancer
CA2411859A1 (fr) Nouveaux derives oxazolidinone et processus de preparation de ces derives
US11685740B2 (en) Bicyclic nitrogen-containing heterocyclic derivatives and pharmaceutical composition comprising the same
KR20010031953A (ko) 옥사졸리디논 유도체 및 제약 조성물
WO2017209265A1 (fr) Dérivé hétérocyclique bicyclique et composition pharmaceutique comprenant le dérivé hétérocyclique bicyclique
JP5662940B2 (ja) 新規な抗微生物薬
JP2019182865A (ja) 二環性含窒素複素環誘導体を含有する医薬組成物
EP0500686B1 (fr) Agents antibacteriens d'oxazolidinone tricycliques [6,5,5]/[6,6,5]-fusionnes
JP2000229978A (ja) オキサゾリジノン及び抗菌剤としてのそれらの使用
KR101293384B1 (ko) 신규 피리딜 벤조옥사진 유도체, 이를 포함하는 약학 조성물 및 이의 용도
KR20210038632A (ko) 포유류 감염 치료를 위한 신규 화합물
KR100467309B1 (ko) 옥사졸리디논유도체및그의제조방법및항균제조성물
RU2798336C2 (ru) Новые соединения для лечения инфекций млекопитающих
WO2024069378A1 (fr) Nouveaux composés pour le traitement d'infections de mammifères
WO2014195718A1 (fr) Dérivés de 3,4-dihydroxy-pyrroles servant d'agents antibactériens