LV12103B - 5-alfa-reduktāzes inhibitora pielietojums androgēnās alopēcijas ārstēšanai - Google Patents
5-alfa-reduktāzes inhibitora pielietojums androgēnās alopēcijas ārstēšanai Download PDFInfo
- Publication number
- LV12103B LV12103B LVP-98-49A LV980049A LV12103B LV 12103 B LV12103 B LV 12103B LV 980049 A LV980049 A LV 980049A LV 12103 B LV12103 B LV 12103B
- Authority
- LV
- Latvia
- Prior art keywords
- finasteride
- androgenic alopecia
- treatment
- day
- reductase
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
- A61Q7/02—Preparations for inhibiting or slowing hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Birds (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Claims (3)
1 LV 12103 Izgudrojuma formula 1. 17b-(N-t-butilkarbamoil)-4-aza-5-alfaandrost-1-ēn-3-ona pielietojums tāda orāli ievadāma medikamenta ražošanai, kas paredzēts androgēnās alopēcijas ārstēšanai, un satur 0,05 -1 mg aktīvās vielas vienā devā.
2. Pielietojums pēc 1. punkta, kurā deva ir 1,0 mg.
3. Pielietojums pēc 1. vai 2. punkta, kurā ārstējamā alopēcija ir vīriešu alopēcija.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13852093A | 1993-10-15 | 1993-10-15 | |
US08/214,905 US5547957A (en) | 1993-10-15 | 1994-03-17 | Method of treating androgenic alopecia with 5-α reductase inhibitors |
Publications (2)
Publication Number | Publication Date |
---|---|
LV12103A LV12103A (lv) | 1998-08-20 |
LV12103B true LV12103B (lv) | 1998-10-20 |
Family
ID=26836279
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LVP-98-49A LV12103B (lv) | 1993-10-15 | 1998-03-12 | 5-alfa-reduktāzes inhibitora pielietojums androgēnās alopēcijas ārstēšanai |
Country Status (28)
Country | Link |
---|---|
US (3) | US5824686A (lv) |
EP (1) | EP0724444B1 (lv) |
JP (1) | JP3058351B2 (lv) |
CN (1) | CN1096861C (lv) |
AT (1) | ATE156358T1 (lv) |
BG (1) | BG62756B1 (lv) |
BR (1) | BR9407824A (lv) |
CA (1) | CA2173457C (lv) |
CY (1) | CY2071B1 (lv) |
CZ (1) | CZ287104B6 (lv) |
DE (1) | DE69404854T2 (lv) |
DK (1) | DK0724444T3 (lv) |
DZ (1) | DZ1817A1 (lv) |
ES (1) | ES2105774T3 (lv) |
FI (1) | FI961632A (lv) |
GR (1) | GR3024375T3 (lv) |
HR (1) | HRP940673B1 (lv) |
HU (1) | HU227861B1 (lv) |
IL (1) | IL111293A (lv) |
LV (1) | LV12103B (lv) |
MX (1) | MXPA99002296A (lv) |
NO (1) | NO309927B1 (lv) |
NZ (1) | NZ275678A (lv) |
PL (1) | PL184930B1 (lv) |
RO (1) | RO116864B1 (lv) |
SK (1) | SK282352B6 (lv) |
TW (1) | TW382595B (lv) |
WO (1) | WO1995010284A1 (lv) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5547957A (en) * | 1993-10-15 | 1996-08-20 | Merck & Co., Inc. | Method of treating androgenic alopecia with 5-α reductase inhibitors |
NL1005445C2 (nl) * | 1997-03-05 | 1998-09-21 | Gho St Holding B V | Werkwijze voor het vermenigvuldigen van haar. |
US5935968A (en) | 1997-03-17 | 1999-08-10 | Merck & Co., Inc. | Methods for treating polycystic ovary syndrome |
IL134199A0 (en) | 1997-07-29 | 2001-04-30 | Sankyo Co | MEDICAMENTS CONTAINING 5α-ANDROST-1-ENE-17β-CARBOXAMIDE DERIVATIVES |
US6348348B1 (en) * | 1998-04-07 | 2002-02-19 | The Carnegie Institution Of Washington | Human hairless gene and protein |
IL124764A0 (en) * | 1998-06-04 | 1999-01-26 | Univ Ben Gurion | Topical composition for treatment of baldness |
DE69935350T2 (de) | 1998-11-20 | 2007-11-22 | The General Hospital Corp., Boston | Verwendung von pyrethroidverbindungen zur förderung des haarwuchses |
AU6087700A (en) * | 1999-07-15 | 2001-02-05 | Procter & Gamble Company, The | Nitrogen-containing steroid compounds and their use to regulate hair growth |
ES2158828B1 (es) * | 2000-02-22 | 2002-03-16 | Tobajas Maximo Gomez | Metodo cosmetico para estimular el nacimiento y el crecimiento del cabello. |
WO2002019974A1 (fr) * | 2000-09-04 | 2002-03-14 | Ravi Shrivastava | Associations synergiques a base de plantes pour traiter la chute des cheveux |
PT1262177E (pt) * | 2001-05-31 | 2006-12-29 | Pfizer Prod Inc | Utilização medicinal de compostos tiromimético para tratamento da queda de cabelo e composições |
US6645974B2 (en) | 2001-07-31 | 2003-11-11 | Merck & Co., Inc. | Androgen receptor modulators and methods for use thereof |
CA2479992A1 (en) | 2002-04-24 | 2003-11-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical combination for the treatment of benign prostatic hyperplasia or for the long-term prevention of acute urinary retention |
FR2954124B1 (fr) * | 2009-12-18 | 2012-04-06 | Fabre Pierre Dermo Cosmetique | Utilisation du 2,3-dihydroxypropyl dodecanoate pour le traitement de la seborrhee |
EP2600822A2 (en) * | 2010-08-05 | 2013-06-12 | Legacy Healthcare Holding Ltd. | Method for stimulating hair growth |
ES2647680T3 (es) * | 2011-01-21 | 2017-12-26 | Igisu Co., Ltd. | Fármaco terapéutico para la alopecia |
GB201102913D0 (en) | 2011-02-18 | 2011-04-06 | Univ Birmingham | Novel therapeutic |
US9345703B2 (en) | 2011-09-15 | 2016-05-24 | University Of Kansas | Kappa opioid receptor effectors and uses thereof |
EP2703003A1 (en) | 2012-08-31 | 2014-03-05 | Probelte Biotecnologia S.L. | A pomegranate extract and compositions containing pomegranate polyphenols for treating or preventing diseases or physiopathological conditions associated with an excessive gene expression and/or physiological activity of interleukin-6 |
EP3638198B1 (de) * | 2017-06-16 | 2021-08-18 | Capilli Med GmbH | Zusammensetzung zur verhinderung von haarausfall und wachstumsförderung von haaren |
US11331300B2 (en) * | 2017-12-22 | 2022-05-17 | Richard Postrel | Reversing baldness through follicle regeneration |
WO2020263115A1 (ru) | 2019-06-28 | 2020-12-30 | Общество С Ограниченной Ответственностью "Регеус" | Средство для усиления роста волос |
FR3106058B1 (fr) * | 2020-01-09 | 2022-01-07 | Oreal | Procédé de traitement cosmétique |
CN113398263B (zh) * | 2021-08-06 | 2022-11-11 | 广东巧巧生物科技有限公司 | 一种治疗脱发的洗发水 |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU527030B2 (en) * | 1978-04-13 | 1983-02-10 | Merck & Co., Inc. | 4-aza-17-substituted-5a-androstan-3-ones |
US4377584A (en) * | 1978-04-13 | 1983-03-22 | Merck & Co., Inc. | 4-Aza-17β-substituted-5α-androstan-3-one-reductase inhibitors |
US4396615A (en) * | 1981-06-24 | 1983-08-02 | Duke University | Method of treating androgen-related disorders |
US4885289A (en) * | 1983-12-12 | 1989-12-05 | Breuer Miklos M | Alteration of character of male beard growth |
US4760071A (en) * | 1984-02-27 | 1988-07-26 | Merck & Co., Inc. | 17β-N-monosubstituted carbamoyl-4-aza-5α-androst-1-en-3-ones which are active as testosterone 5α-reductase inhibitors |
NZ211145A (en) * | 1984-02-27 | 1988-10-28 | Merck & Co Inc | 4-aza-5-alpha-androst-1-en-3-ones and pharmaceutical compositions |
US5571817A (en) * | 1984-02-27 | 1996-11-05 | Merck & Co., Inc. | Methods of treating androgenic alopecia with finasteride [17β-N-mono-substituted-carbamoyl-4-aza-5-α-androst-1-en-ones] |
ZA851426B (en) | 1984-02-27 | 1986-10-29 | Merck & Co Inc | 17 beta-n-monosubstituted carbamoyl-4-aza-5 alpha-androst-1-en-3-ones as 5 alpha reductase inhibitors |
US4684635A (en) * | 1984-05-11 | 1987-08-04 | Norman Orentreich | Compositions and methods for inhibiting the action of androgens |
US5053403A (en) * | 1984-05-11 | 1991-10-01 | Norman Orentreich | Methods for treatment of male-pattern baldness |
DE3888994T2 (de) * | 1987-04-03 | 1994-11-03 | Merck & Co Inc | Behandlung von androgener Alopecia mit 17-beta-n-mono-substituierten-carbamoyl-4-aza-5-alpha-androst-1-en-3-onen. |
US5228431A (en) * | 1990-04-26 | 1993-07-20 | Giarretto Ralph R | Drug-free method for treatment of the scalp for therapeutic purposes |
JP3004718B2 (ja) * | 1990-08-10 | 2000-01-31 | ファルマシア・アンド・アップジョン・カンパニー | カリウムチャネルオープナーおよび5α―レダクターゼ抑制剤を用いる育毛刺激 |
US5175155A (en) * | 1991-10-07 | 1992-12-29 | Sterling Winthrop Inc. | Win 49596-finasteride method of use and compositions |
EP0649306B1 (en) * | 1992-05-20 | 2001-01-10 | Merck & Co. Inc. | Ester derivatives of 4-aza-steroids |
US5795882A (en) * | 1992-06-22 | 1998-08-18 | Bone Care International, Inc. | Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations |
US5407944A (en) * | 1993-02-19 | 1995-04-18 | Goldman; Boris E. | Compositions and methods for promoting hair growth |
US5438061A (en) * | 1993-07-16 | 1995-08-01 | Merck & Co., Inc. | 7-substituted-δ4-6-azasteroid derivatives as 5α-reductase inhibitors |
TW369521B (en) * | 1993-09-17 | 1999-09-11 | Smithkline Beecham Corp | Androstenone derivative |
US5547957A (en) * | 1993-10-15 | 1996-08-20 | Merck & Co., Inc. | Method of treating androgenic alopecia with 5-α reductase inhibitors |
US5708001A (en) * | 1993-12-17 | 1998-01-13 | Glaxo Wellcome Inc. | Substituted 6-azaandrostenones |
US5525608A (en) * | 1994-04-20 | 1996-06-11 | Merck & Co., Inc. | 17b-aryl-4-aza-steroid derivatives useful as 5-alpha-reductase inhibitors |
US5512555A (en) * | 1994-07-21 | 1996-04-30 | Merck & Co., Inc. | Method of treating sweat-related conditions using finasteride, epristeride and a cholestan-3-one |
US5595996A (en) * | 1994-10-25 | 1997-01-21 | Merck & Co., Inc. | 7-substituted 4-aza cholanic acid derivatives and their use |
US5777134A (en) * | 1995-10-26 | 1998-07-07 | Merck & Co., Inc. | 4-oxa and 4-thia steriods |
US5780437A (en) * | 1995-12-14 | 1998-07-14 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
US5756507A (en) * | 1995-12-14 | 1998-05-26 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
US5849764A (en) * | 1995-12-14 | 1998-12-15 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
-
1994
- 1994-10-07 TW TW083109300A patent/TW382595B/zh not_active IP Right Cessation
- 1994-10-11 HU HU9600976A patent/HU227861B1/hu unknown
- 1994-10-11 CA CA002173457A patent/CA2173457C/en not_active Expired - Lifetime
- 1994-10-11 DK DK94930701.1T patent/DK0724444T3/da active
- 1994-10-11 PL PL94316854A patent/PL184930B1/pl unknown
- 1994-10-11 BR BR9407824A patent/BR9407824A/pt not_active Application Discontinuation
- 1994-10-11 WO PCT/US1994/011507 patent/WO1995010284A1/en active IP Right Grant
- 1994-10-11 CZ CZ19961081A patent/CZ287104B6/cs not_active IP Right Cessation
- 1994-10-11 AT AT94930701T patent/ATE156358T1/de active
- 1994-10-11 EP EP94930701A patent/EP0724444B1/en not_active Expired - Lifetime
- 1994-10-11 NZ NZ275678A patent/NZ275678A/en not_active IP Right Cessation
- 1994-10-11 CN CN94194471A patent/CN1096861C/zh not_active Ceased
- 1994-10-11 SK SK448-96A patent/SK282352B6/sk not_active IP Right Cessation
- 1994-10-11 RO RO96-00793A patent/RO116864B1/ro unknown
- 1994-10-11 DE DE69404854T patent/DE69404854T2/de not_active Expired - Lifetime
- 1994-10-11 US US08/596,339 patent/US5824686A/en not_active Expired - Lifetime
- 1994-10-11 ES ES94930701T patent/ES2105774T3/es not_active Expired - Lifetime
- 1994-10-11 JP JP7511986A patent/JP3058351B2/ja not_active Expired - Lifetime
- 1994-10-12 HR HR08/214,905A patent/HRP940673B1/xx not_active IP Right Cessation
- 1994-10-12 DZ DZ940107A patent/DZ1817A1/fr active
- 1994-10-13 IL IL11129394A patent/IL111293A/en not_active IP Right Cessation
-
1996
- 1996-02-14 US US08/601,497 patent/US5760046A/en not_active Expired - Fee Related
- 1996-04-12 FI FI961632A patent/FI961632A/fi not_active Application Discontinuation
- 1996-04-15 NO NO961497A patent/NO309927B1/no not_active IP Right Cessation
- 1996-04-16 BG BG100510A patent/BG62756B1/bg unknown
-
1997
- 1997-08-07 GR GR970401888T patent/GR3024375T3/el unknown
-
1998
- 1998-03-12 LV LVP-98-49A patent/LV12103B/lv unknown
- 1998-06-22 US US09/102,454 patent/US5981543A/en not_active Expired - Fee Related
- 1998-09-11 CY CY9802071A patent/CY2071B1/xx unknown
-
1999
- 1999-03-09 MX MXPA99002296A patent/MXPA99002296A/es active IP Right Grant
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