LV12103A - 5-alfa-reduktazes inhibitora pielietojums androgenas alopecijas arstesanai - Google Patents

5-alfa-reduktazes inhibitora pielietojums androgenas alopecijas arstesanai

Info

Publication number
LV12103A
LV12103A LV980049A LV980049A LV12103A LV 12103 A LV12103 A LV 12103A LV 980049 A LV980049 A LV 980049A LV 980049 A LV980049 A LV 980049A LV 12103 A LV12103 A LV 12103A
Authority
LV
Latvia
Prior art keywords
alpha
treatment
reductase inhibitor
androgen alopecia
treating
Prior art date
Application number
LV980049A
Other languages
English (en)
Other versions
LV12103B (lv
Inventor
Glenn J Gormley
Keith D Kaufman
Elizabeth Stoner
Joanne Waldstreicher
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26836279&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LV12103(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/214,905 external-priority patent/US5547957A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of LV12103A publication Critical patent/LV12103A/lv
Publication of LV12103B publication Critical patent/LV12103B/lv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A61Q7/02—Preparations for inhibiting or slowing hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists
LVP-98-49A 1993-10-15 1998-03-12 5-alfa-reduktāzes inhibitora pielietojums androgēnās alopēcijas ārstēšanai LV12103B (lv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13852093A 1993-10-15 1993-10-15
US08/214,905 US5547957A (en) 1993-10-15 1994-03-17 Method of treating androgenic alopecia with 5-α reductase inhibitors

Publications (2)

Publication Number Publication Date
LV12103A true LV12103A (lv) 1998-08-20
LV12103B LV12103B (lv) 1998-10-20

Family

ID=26836279

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-98-49A LV12103B (lv) 1993-10-15 1998-03-12 5-alfa-reduktāzes inhibitora pielietojums androgēnās alopēcijas ārstēšanai

Country Status (28)

Country Link
US (3) US5824686A (lv)
EP (1) EP0724444B1 (lv)
JP (1) JP3058351B2 (lv)
CN (1) CN1096861C (lv)
AT (1) ATE156358T1 (lv)
BG (1) BG62756B1 (lv)
BR (1) BR9407824A (lv)
CA (1) CA2173457C (lv)
CY (1) CY2071B1 (lv)
CZ (1) CZ287104B6 (lv)
DE (1) DE69404854T2 (lv)
DK (1) DK0724444T3 (lv)
DZ (1) DZ1817A1 (lv)
ES (1) ES2105774T3 (lv)
FI (1) FI961632A (lv)
GR (1) GR3024375T3 (lv)
HR (1) HRP940673B1 (lv)
HU (1) HU227861B1 (lv)
IL (1) IL111293A (lv)
LV (1) LV12103B (lv)
MX (1) MXPA99002296A (lv)
NO (1) NO309927B1 (lv)
NZ (1) NZ275678A (lv)
PL (1) PL184930B1 (lv)
RO (1) RO116864B1 (lv)
SK (1) SK282352B6 (lv)
TW (1) TW382595B (lv)
WO (1) WO1995010284A1 (lv)

Families Citing this family (24)

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Publication number Priority date Publication date Assignee Title
US5547957A (en) * 1993-10-15 1996-08-20 Merck & Co., Inc. Method of treating androgenic alopecia with 5-α reductase inhibitors
NL1005445C2 (nl) * 1997-03-05 1998-09-21 Gho St Holding B V Werkwijze voor het vermenigvuldigen van haar.
US5935968A (en) 1997-03-17 1999-08-10 Merck & Co., Inc. Methods for treating polycystic ovary syndrome
TR200000263T2 (tr) 1997-07-29 2000-09-21 Sankyo Company Limited Alopesi için ilaç.
US6348348B1 (en) 1998-04-07 2002-02-19 The Carnegie Institution Of Washington Human hairless gene and protein
IL124764A0 (en) * 1998-06-04 1999-01-26 Univ Ben Gurion Topical composition for treatment of baldness
DE69935350T2 (de) 1998-11-20 2007-11-22 The General Hospital Corp., Boston Verwendung von pyrethroidverbindungen zur förderung des haarwuchses
AU6087700A (en) * 1999-07-15 2001-02-05 Procter & Gamble Company, The Nitrogen-containing steroid compounds and their use to regulate hair growth
ES2158828B1 (es) * 2000-02-22 2002-03-16 Tobajas Maximo Gomez Metodo cosmetico para estimular el nacimiento y el crecimiento del cabello.
AU2000272974A1 (en) * 2000-09-04 2002-03-22 Ravi Shrivastava Synergetic combinations based on plants for treating hair loss
DK1262177T3 (da) * 2001-05-31 2006-11-20 Pfizer Prod Inc Medicinsk brug af thyromimetiske forbindelser til behandling af hårtab og kompositioner
US6645974B2 (en) 2001-07-31 2003-11-11 Merck & Co., Inc. Androgen receptor modulators and methods for use thereof
EP1501517B1 (en) 2002-04-24 2007-05-02 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG Pharmaceutical combination for the treatment of benign prostatic hyperplasia or for the long-term prevention of acute urinary retention
FR2954124B1 (fr) * 2009-12-18 2012-04-06 Fabre Pierre Dermo Cosmetique Utilisation du 2,3-dihydroxypropyl dodecanoate pour le traitement de la seborrhee
KR20140003373A (ko) * 2010-08-05 2014-01-09 레가시 헬스케어 홀딩 리미티드 모발 성장 자극 방법
CN110801514A (zh) * 2011-01-21 2020-02-18 Igisu株式会社 秃头症治疗剂
GB201102913D0 (en) 2011-02-18 2011-04-06 Univ Birmingham Novel therapeutic
WO2013040321A1 (en) 2011-09-15 2013-03-21 University Of Kansas Kappa opioid receptor effectors and uses thereof
EP2703003A1 (en) 2012-08-31 2014-03-05 Probelte Biotecnologia S.L. A pomegranate extract and compositions containing pomegranate polyphenols for treating or preventing diseases or physiopathological conditions associated with an excessive gene expression and/or physiological activity of interleukin-6
SI3638198T1 (sl) * 2017-06-16 2022-02-28 Capilli Med Gmbh Sestavek za preprečevanje izgube las in spodbujanje rasti las
US11331300B2 (en) * 2017-12-22 2022-05-17 Richard Postrel Reversing baldness through follicle regeneration
CN114025768B (zh) 2019-06-28 2023-12-22 古鲁生物制药有限公司 促进毛发生长的药品
FR3106058B1 (fr) * 2020-01-09 2022-01-07 Oreal Procédé de traitement cosmétique
CN113398263B (zh) * 2021-08-06 2022-11-11 广东巧巧生物科技有限公司 一种治疗脱发的洗发水

Family Cites Families (28)

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Publication number Priority date Publication date Assignee Title
AU527030B2 (en) * 1978-04-13 1983-02-10 Merck & Co., Inc. 4-aza-17-substituted-5a-androstan-3-ones
US4377584A (en) * 1978-04-13 1983-03-22 Merck & Co., Inc. 4-Aza-17β-substituted-5α-androstan-3-one-reductase inhibitors
US4396615A (en) * 1981-06-24 1983-08-02 Duke University Method of treating androgen-related disorders
US4885289A (en) * 1983-12-12 1989-12-05 Breuer Miklos M Alteration of character of male beard growth
ZA851426B (en) 1984-02-27 1986-10-29 Merck & Co Inc 17 beta-n-monosubstituted carbamoyl-4-aza-5 alpha-androst-1-en-3-ones as 5 alpha reductase inhibitors
US4760071A (en) * 1984-02-27 1988-07-26 Merck & Co., Inc. 17β-N-monosubstituted carbamoyl-4-aza-5α-androst-1-en-3-ones which are active as testosterone 5α-reductase inhibitors
NZ211145A (en) * 1984-02-27 1988-10-28 Merck & Co Inc 4-aza-5-alpha-androst-1-en-3-ones and pharmaceutical compositions
US5571817A (en) * 1984-02-27 1996-11-05 Merck & Co., Inc. Methods of treating androgenic alopecia with finasteride [17β-N-mono-substituted-carbamoyl-4-aza-5-α-androst-1-en-ones]
US4684635A (en) * 1984-05-11 1987-08-04 Norman Orentreich Compositions and methods for inhibiting the action of androgens
US5053403A (en) * 1984-05-11 1991-10-01 Norman Orentreich Methods for treatment of male-pattern baldness
EP0285382B1 (en) * 1987-04-03 1994-04-13 Merck & Co. Inc. Treatment of androgenic alopecia with 17beta-n-monosubstituted-carbamoyl-4-aza-5alpha-androst-1-en-3-ones
US5228431A (en) * 1990-04-26 1993-07-20 Giarretto Ralph R Drug-free method for treatment of the scalp for therapeutic purposes
KR100192734B1 (ko) * 1990-08-10 1999-06-15 로버트 에이. 아미테이지 칼륨 통로 개방제 및 5알파-환원효소 억제제를 사용하는 모발 성장의 자극 방법
US5175155A (en) * 1991-10-07 1992-12-29 Sterling Winthrop Inc. Win 49596-finasteride method of use and compositions
ATE198601T1 (de) * 1992-05-20 2001-01-15 Merck & Co Inc Ester derivate von 4-aza-steroiden
US5795882A (en) * 1992-06-22 1998-08-18 Bone Care International, Inc. Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations
US5407944A (en) * 1993-02-19 1995-04-18 Goldman; Boris E. Compositions and methods for promoting hair growth
US5438061A (en) * 1993-07-16 1995-08-01 Merck & Co., Inc. 7-substituted-δ4-6-azasteroid derivatives as 5α-reductase inhibitors
TW369521B (en) * 1993-09-17 1999-09-11 Smithkline Beecham Corp Androstenone derivative
US5547957A (en) * 1993-10-15 1996-08-20 Merck & Co., Inc. Method of treating androgenic alopecia with 5-α reductase inhibitors
US5708001A (en) * 1993-12-17 1998-01-13 Glaxo Wellcome Inc. Substituted 6-azaandrostenones
US5525608A (en) * 1994-04-20 1996-06-11 Merck & Co., Inc. 17b-aryl-4-aza-steroid derivatives useful as 5-alpha-reductase inhibitors
US5512555A (en) * 1994-07-21 1996-04-30 Merck & Co., Inc. Method of treating sweat-related conditions using finasteride, epristeride and a cholestan-3-one
US5595996A (en) * 1994-10-25 1997-01-21 Merck & Co., Inc. 7-substituted 4-aza cholanic acid derivatives and their use
US5777134A (en) * 1995-10-26 1998-07-07 Merck & Co., Inc. 4-oxa and 4-thia steriods
US5849764A (en) * 1995-12-14 1998-12-15 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US5780437A (en) * 1995-12-14 1998-07-14 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US5756507A (en) * 1995-12-14 1998-05-26 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone

Also Published As

Publication number Publication date
DE69404854T2 (de) 1998-02-19
NZ275678A (en) 1999-09-29
HUT74426A (en) 1996-12-30
DZ1817A1 (fr) 2002-02-17
WO1995010284A1 (en) 1995-04-20
RO116864B1 (ro) 2001-07-30
US5981543A (en) 1999-11-09
IL111293A0 (en) 1994-12-29
US5760046A (en) 1998-06-02
SK282352B6 (sk) 2002-01-07
HU227861B1 (en) 2012-05-02
FI961632A0 (fi) 1996-04-12
IL111293A (en) 1998-08-16
HRP940673B1 (en) 2000-02-29
CZ108196A3 (en) 1996-08-14
PL316854A1 (en) 1997-02-17
EP0724444B1 (en) 1997-08-06
TW382595B (en) 2000-02-21
GR3024375T3 (en) 1997-11-28
DK0724444T3 (da) 1997-09-15
MXPA99002296A (es) 2004-08-27
BG62756B1 (bg) 2000-07-31
BG100510A (en) 1996-11-29
CA2173457C (en) 1999-03-23
JP3058351B2 (ja) 2000-07-04
NO961497L (no) 1996-04-15
BR9407824A (pt) 1997-05-06
CZ287104B6 (en) 2000-09-13
CA2173457A1 (en) 1995-04-20
ES2105774T3 (es) 1997-10-16
NO309927B1 (no) 2001-04-23
JPH09505034A (ja) 1997-05-20
DE69404854D1 (de) 1997-09-11
NO961497D0 (no) 1996-04-15
EP0724444A1 (en) 1996-08-07
SK44896A3 (en) 1997-03-05
ATE156358T1 (de) 1997-08-15
US5824686A (en) 1998-10-20
HRP940673A2 (en) 1997-02-28
PL184930B1 (pl) 2003-01-31
CN1137237A (zh) 1996-12-04
AU688395B2 (en) 1998-03-12
CY2071B1 (en) 1998-09-11
LV12103B (lv) 1998-10-20
AU7974294A (en) 1995-05-04
CN1096861C (zh) 2002-12-25
FI961632A (fi) 1996-04-12
HU9600976D0 (en) 1996-06-28

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